PDB: 166 件ウェブページステータス検索Chemie searchBIRD

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7RY3	Multidrug Efflux pump AdeJ with TP-6076 bound 分子名称: (4S,4aS,5aR,12aS)-4-(diethylamino)-3,10,12,12a-tetrahydroxy-1,11-dioxo-8-[(2S)-pyrrolidin-2-yl]-7-(trifluoromethyl)-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide, Efflux pump membrane transporter 著者 Zhang, Z. 登録日 2021-08-24 公開日 2022-02-02 最終更新日 2024-06-05 実験手法 ELECTRON MICROSCOPY (2.91 Å) 主引用文献 An Analysis of the Novel Fluorocycline TP-6076 Bound to Both the Ribosome and Multidrug Efflux Pump AdeJ from Acinetobacter baumannii. Mbio, 13, 2022
3D9B	Symmetric structure of E. coli AcrB 分子名称: Acriflavine resistance protein B, NICKEL (II) ION 著者 Veesler, D, Blangy, S, Cambillau, C, Sciara, G. 登録日 2008-05-27 公開日 2008-07-01 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (3.42 Å) 主引用文献 There is a baby in the bath water: AcrB contamination is a major problem in membrane-protein crystallization. Acta Crystallogr.,Sect.F, 64, 2008
5JMN	Fusidic acid bound AcrB 分子名称: 2-{2-[2-2-(METHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, 3,6,9,12,15-PENTAOXAHEPTADECANE, DARPin, ... 著者 Oswald, C, Tam, H.K, Pos, K.M. 登録日 2016-04-29 公開日 2016-12-21 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Transport of lipophilic carboxylates is mediated by transmembrane helix 2 in multidrug transporter AcrB. Nat Commun, 7, 2016
1IWG	Crystal structure of Bacterial Multidrug Efflux transporter AcrB 分子名称: AcrB 著者 Murakami, S, Nakashima, R, Yamashita, E, Yamaguchi, A. 登録日 2002-05-15 公開日 2002-10-23 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (3.5 Å) 主引用文献 Crystal structure of bacterial multidrug efflux transporter AcrB NATURE, 419, 2002
2GIF	Asymmetric structure of trimeric AcrB from Escherichia coli 分子名称: Acriflavine resistance protein B, CITRATE ANION 著者 Seeger, M.A, Schiefner, A, Eicher, T, Verrey, F, Diederichs, K, Pos, K.M. 登録日 2006-03-28 公開日 2006-09-12 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Structural Asymmetry of AcrB Trimer Suggests a Peristaltic Pump Mechanism. Science, 313, 2006
5YIL	Hoisting-loop in bacterial multidrug exporter AcrB is a highly flexible hinge that enables the large motion of the subdomains 分子名称: Multidrug efflux pump subunit AcrB 著者 Zwama, M, Sakurai, K, Hayashi, K, Nakashima, R, Kitagawa, K, Nishino, K, Yamaguchi, A. 登録日 2017-10-05 公開日 2017-11-15 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Hoisting-Loop in Bacterial Multidrug Exporter AcrB Is a Highly Flexible Hinge That Enables the Large Motion of the Subdomains. Front Microbiol, 8, 2017
6Z12	Salmonella AcrB solubilised in the SMA copolymer 分子名称: Efflux pump membrane transporter 著者 Muench, s.p, Johnson, R.M. 登録日 2020-05-11 公開日 2020-07-22 最終更新日 2024-05-15 実験手法 ELECTRON MICROSCOPY (4.6 Å) 主引用文献 Cryo-EM Structure and Molecular Dynamics Analysis of the Fluoroquinolone Resistant Mutant of the AcrB Transporter fromSalmonella. Microorganisms, 8, 2020
6NZI	Low resolution crystal structure of the bacterial multidrug efflux transporter AcrB in the presence of cadmium 分子名称: CADMIUM ION, Efflux pump membrane transporter 著者 Smith, A.T, Rosenzweig, A.C. 登録日 2019-02-13 公開日 2019-02-27 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (4.44 Å) 主引用文献 Low resolution crystal structure of the bacterial multidrug efflux transporter AcrB in the presence of cadmium To Be Published
5LQ3	Structures and transport dynamics of the Campylobacter jejuni multidrug efflux pump CmeB 分子名称: CmeB 著者 Su, C.C. 登録日 2016-08-15 公開日 2017-08-09 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (3.55 Å) 主引用文献 Structures and transport dynamics of a Campylobacter jejuni multidrug efflux pump. Nat Commun, 8, 2017
5T0O	Crystal Structure of a membrane protein 分子名称: CmeB 著者 Su, C.-C, Yu, E.W. 登録日 2016-08-16 公開日 2017-09-06 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (3.15 Å) 主引用文献 Structures and transport dynamics of a Campylobacter jejuni multidrug efflux pump. Nat Commun, 8, 2017
3KSO	Structure and Mechanism of the Heavy Metal Transporter CusA 分子名称: Cation efflux system protein cusA, SILVER ION 著者 Su, C.-C. 登録日 2009-11-23 公開日 2010-09-22 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (4.367 Å) 主引用文献 Crystal structures of the CusA efflux pump suggest methionine-mediated metal transport. Nature, 467, 2010
6BAJ	Cryo-EM structure of lipid bilayer in the native cell membrane nanoparticles of AcrB 分子名称: DODECANE, Multidrug efflux pump subunit AcrB, PHOSPHATIDYLETHANOLAMINE 著者 Qiu, W, Fu, Z, Guo, Y. 登録日 2017-10-13 公開日 2018-12-19 最終更新日 2024-03-13 実験手法 ELECTRON MICROSCOPY (3.2 Å) 主引用文献 Structure and activity of lipid bilayer within a membrane-protein transporter. Proc.Natl.Acad.Sci.USA, 115, 2018
3KSS	Structure and Mechanism of the Heavy Metal Transporter CusA 分子名称: COPPER (I) ION, Cation efflux system protein cusA 著者 Su, C.-C. 登録日 2009-11-23 公開日 2010-09-22 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (3.88 Å) 主引用文献 Crystal structures of the CusA efflux pump suggest methionine-mediated metal transport. Nature, 467, 2010
7WLV	Crystal Structure of the Multidrug effulx transporter BpeF from Burkholderia pseudomallei. 分子名称: DODECYL-BETA-D-MALTOSIDE, Efflux pump membrane transporter 著者 Kato, T, Hung, L.-W, Yamashita, E, Okada, U, Terwilliger, T.C, Murakami, S. 登録日 2022-01-13 公開日 2023-07-19 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Crystal structures of multidrug efflux transporters from Burkholderia pseudomallei suggest details of transport mechanism. Proc.Natl.Acad.Sci.USA, 120, 2023
2W1B	The structure of the efflux pump AcrB in complex with bile acid 分子名称: (3ALPHA,5BETA,12ALPHA)-3,12-DIHYDROXYCHOLAN-24-OIC ACID, ACRIFLAVIN RESISTANCE PROTEIN B 著者 Drew, D, Klepsch, M.M, Newstead, S, Flaig, R, De Gier, J.W, Iwata, S, Beis, K. 登録日 2008-10-17 公開日 2008-12-09 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (3.85 Å) 主引用文献 The Structure of the Efflux Pump Acrb in Complex with Bile Acid. Mol.Membr.Biol., 25, 2008
7M4P	Multidrug Efflux pump AdeJ with Eravacycline bound 分子名称: 1,2-Distearoyl-sn-glycerophosphoethanolamine, Efflux pump membrane transporter, Eravacycline 著者 Zhang, Z. 登録日 2021-03-22 公開日 2021-05-19 最終更新日 2024-05-29 実験手法 ELECTRON MICROSCOPY (2.86 Å) 主引用文献 Cryo-EM Determination of Eravacycline-Bound Structures of the Ribosome and the Multidrug Efflux Pump AdeJ of Acinetobacter baumannii. Mbio, 12, 2021
7M4Q	Multidrug Efflux pump AdeJ 分子名称: 1,2-Distearoyl-sn-glycerophosphoethanolamine, Efflux pump membrane transporter 著者 Zhang, Z. 登録日 2021-03-22 公開日 2021-05-19 最終更新日 2024-05-29 実験手法 ELECTRON MICROSCOPY (2.87 Å) 主引用文献 Cryo-EM Determination of Eravacycline-Bound Structures of the Ribosome and the Multidrug Efflux Pump AdeJ of Acinetobacter baumannii. Mbio, 12, 2021
7WLS	Crystal structure of the multidrug efflux transporter BpeB from Burkholderia pseudomallei 分子名称: Efflux pump membrane transporter, TETRAETHYLENE GLYCOL, UNDECYL-MALTOSIDE 著者 Kato, T, Hung, L.-W, Yamashita, E, Okada, U, Terwilliger, T.C, Murakami, S. 登録日 2022-01-13 公開日 2023-07-19 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.94 Å) 主引用文献 Crystal structures of multidrug efflux transporters from Burkholderia pseudomallei suggest details of transport mechanism. Proc.Natl.Acad.Sci.USA, 120, 2023
8PX7	Structure of Bacterial Multidrug Efflux transporter AcrB, solved at wavelength 3.02 A 分子名称: Multidrug efflux pump subunit AcrB 著者 El Omari, K, Duman, R, Mykhaylyk, V, Orr, C, Qu, F, Beis, K, Wagner, A. 登録日 2023-07-22 公開日 2023-10-25 実験手法 X-RAY DIFFRACTION (3.4 Å) 主引用文献 Experimental phasing opportunities for macromolecular crystallography at very long wavelengths. Commun Chem, 6, 2023
3K0I	Crystal structure of Cu(I)CusA 分子名称: COPPER (I) ION, Cation efflux system protein cusA 著者 Su, C.-C. 登録日 2009-09-24 公開日 2010-10-13 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (4.116 Å) 主引用文献 Crystal structure of CusA To be Published
6CSX	Single particles Cryo-EM structure of AcrB D407A associated with lipid bilayer at 3.0 Angstrom 分子名称: DODECANE, Multidrug efflux pump subunit AcrB, PHOSPHATIDYLETHANOLAMINE 著者 Qiu, W, Fu, Z, Guo, Y. 登録日 2018-03-21 公開日 2018-12-05 最終更新日 2024-03-13 実験手法 ELECTRON MICROSCOPY (3 Å) 主引用文献 Structure and activity of lipid bilayer within a membrane-protein transporter. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
8P1I	Single particle cryo-EM co-structure of Klebsiella pneumoniae AcrB with the BDM91288 efflux pump inhibitor at 2.97 Angstrom resolution 分子名称: 1,2-DIOCTANOYL-SN-GLYCERO-3-[PHOSPHO-RAC-(1-GLYCEROL), 3-chloranyl-2,6-di(piperazin-4-ium-1-yl)quinoline, Efflux pump membrane transporter, ... 著者 Boernsen, C, Mueller, R.T, Pos, K.M, Frangakis, A.S. 登録日 2023-05-12 公開日 2024-01-17 最終更新日 2024-01-31 実験手法 ELECTRON MICROSCOPY (2.97 Å) 主引用文献 Pyridylpiperazine efflux pump inhibitor boosts in vivo antibiotic efficacy against K. pneumoniae. Embo Mol Med, 16, 2024
2V50	The Missing Part of the Bacterial MexAB-OprM System: Structural determination of the Multidrug Exporter MexB 分子名称: DODECYL-BETA-D-MALTOSIDE, MULTIDRUG RESISTANCE PROTEIN MEXB 著者 Sennhauser, G, Bukowska, M.A, Gruetter, M.G. 登録日 2008-10-01 公開日 2009-05-19 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Crystal Structure of the Multidrug Exporter Mexb from Pseudomonas Aeruginosa. J.Mol.Biol., 389, 2009
3K07	Crystal structure of CusA 分子名称: Cation efflux system protein cusA 著者 Su, C.-C. 登録日 2009-09-24 公開日 2010-09-22 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (3.521 Å) 主引用文献 Crystal structures of the CusA efflux pump suggest methionine-mediated metal transport. Nature, 467, 2010
4K0E	X-ray crystal structure of a heavy metal efflux pump, crystal form II 分子名称: Heavy metal cation tricomponent efflux pump ZneA(CzcA-like), ZINC ION 著者 Pak, J.E, Ngonlong Ekende, E, Vandenbussche, G, Stroud, R.M, Center for Structures of Membrane Proteins (CSMP) 登録日 2013-04-03 公開日 2013-10-16 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (3.713 Å) 主引用文献 Structures of intermediate transport states of ZneA, a Zn(II)/proton antiporter. Proc.Natl.Acad.Sci.USA, 110, 2013

 

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