2RQ1
 
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3U7D
 | | Crystal structure of the KRIT1/CCM1 FERM domain in complex with the heart of glass (HEG1) cytoplasmic tail | | 分子名称: | Krev interaction trapped protein 1, Protein HEG homolog 1 | | 著者 | Gingras, A.R, Liu, J.J, Ginsberg, M.H, Assembly, Dynamics and Evolution of Cell-Cell and Cell-Matrix Adhesions (CELLMAT) | | 登録日 | 2011-10-13 | | 公開日 | 2012-09-12 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.49 Å) | | 主引用文献 | Structural basis of the junctional anchorage of the cerebral cavernous malformations complex.
J.Cell Biol., 199, 2012
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2HRJ
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1SGH
 | | Moesin FERM domain bound to EBP50 C-terminal peptide | | 分子名称: | Ezrin-radixin-moesin binding phosphoprotein 50, Moesin | | 著者 | Finnerty, C.M, Chambers, D, Ingraffea, J, Faber, H.R, Karplus, P.A, Bretscher, A. | | 登録日 | 2004-02-23 | | 公開日 | 2004-06-29 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (3.5 Å) | | 主引用文献 | The EBP50-moesin interaction involves a binding site regulated by direct masking on the FERM domain
J.Cell.Sci., 117, 2004
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8Y8Y
 | | Crystal structure of the PTPN21 FERM domain | | 分子名称: | CHLORIDE ION, Tyrosine-protein phosphatase non-receptor type 21 | | 著者 | Lee, H.S, Ku, B. | | 登録日 | 2024-02-06 | | 公開日 | 2024-07-10 | | 実験手法 | X-RAY DIFFRACTION (2.099 Å) | | 主引用文献 | Structural analysis of the FERM domain of human protein tyrosine phosphatase non-receptor type 21.
Acta Crystallogr.,Sect.F, 80, 2024
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1J19
 | | Crystal structure of the radxin FERM domain complexed with the ICAM-2 cytoplasmic peptide | | 分子名称: | 16-mer peptide from Intercellular adhesion molecule-2, radixin | | 著者 | Hamada, K, Shimizu, T, Yonemura, S, Tsukita, S, Tsukita, S, Hakoshima, T. | | 登録日 | 2002-12-02 | | 公開日 | 2003-03-11 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Structural basis of adhesion-molecule recognition by ERM proteins revealed by the crystal structure of the radixin-ICAM-2 complex
EMBO J., 22, 2003
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3IVF
 | | Crystal structure of the talin head FERM domain | | 分子名称: | Talin-1 | | 著者 | Elliott, P.R, Goult, B.T, Bate, N, Grossmann, J.G, Roberts, G.C.K, Critchley, D.R, Barsukov, I.L. | | 登録日 | 2009-09-01 | | 公開日 | 2010-08-18 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (1.94 Å) | | 主引用文献 | The Structure of the talin head reveals a novel extended conformation of the FERM domain
Structure, 18, 2010
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6IBE
 | | The FERM domain of Human EPB41L3 | | 分子名称: | 1,2-ETHANEDIOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Band 4.1-like protein 3 | | 著者 | Bradshaw, W.J, Katis, V.L, Newman, J.A, Fernandez-Cid, A, Burgess-Brown, N, von Delft, F, Arrowsmith, C.H, Edwards, A, Bountra, C, Gileadi, O. | | 登録日 | 2018-11-29 | | 公開日 | 2018-12-19 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | | 主引用文献 | The FERM domain of Human EPB41L3
To Be Published
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3G9W
 | | Crystal Structure of Talin2 F2-F3 in Complex with the Integrin Beta1D Cytoplasmic Tail | | 分子名称: | DI(HYDROXYETHYL)ETHER, GLYCEROL, Integrin beta-1D, ... | | 著者 | Anthis, N.J, Wegener, K.L, Ye, F, Kim, C, Lowe, E.D, Vakonakis, I, Bate, N, Critchley, D.R, Ginsberg, M.H, Campbell, I.D. | | 登録日 | 2009-02-15 | | 公開日 | 2009-10-20 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.165 Å) | | 主引用文献 | The structure of an integrin/talin complex reveals the basis of inside-out signal transduction
Embo J., 28, 2009
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6MFS
 | | Mouse talin1 residues 1-138 fused to residues 169-400 in complex with phosphatidylinositol 4,5-bisphosphate (PIP2) | | 分子名称: | PHOSPHATE ION, Talin-1 fusion, [(2R)-2-octanoyloxy-3-[oxidanyl-[(1R,2R,3S,4R,5R,6S)-2,3,6-tris(oxidanyl)-4,5-diphosphonooxy-cyclohexyl]oxy-phosphoryl]oxy-propyl] octanoate | | 著者 | Izard, T, Chinthalapudi, K, Rangarajan, E.S. | | 登録日 | 2018-09-12 | | 公開日 | 2018-09-26 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (2.85 Å) | | 主引用文献 | The interaction of talin with the cell membrane is essential for integrin activation and focal adhesion formation.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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7LWH
 | | Human neurofibromin 2/merlin residues 1-339 in complex with LATS1 | | 分子名称: | GLYCEROL, IMIDAZOLE, Merlin, ... | | 著者 | Primi, M.C, Rangarajan, E.S, Izard, T. | | 登録日 | 2021-03-01 | | 公開日 | 2021-08-11 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (1.606 Å) | | 主引用文献 | Conformational flexibility determines the Nf2/merlin tumor suppressor functions.
Matrix Biol Plus, 12, 2021
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6XTJ
 | | The high resolution structure of the FERM domain of human FERMT2 | | 分子名称: | CITRIC ACID, Fermitin family homolog 2,Fermitin family homolog 2,Fermitin family homolog 2 | | 著者 | Bradshaw, W.J, Katis, V.L, Newman, J.A, von Delft, F, Arrowsmith, C.H, Edwards, A, Bountra, C, Gileadi, O. | | 登録日 | 2020-01-16 | | 公開日 | 2020-02-12 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | The high resolution structure of the FERM domain of human FERMT2
To Be Published
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4NY0
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3PZD
 | | Structure of the myosin X MyTH4-FERM/DCC complex | | 分子名称: | GLYCEROL, Myosin-X, Netrin receptor DCC | | 著者 | Wei, Z, Yan, J, Pan, L, Zhang, M. | | 登録日 | 2010-12-14 | | 公開日 | 2011-02-23 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Cargo recognition mechanism of myosin X revealed by the structure of its tail MyTH4-FERM tandem in complex with the DCC P3 domain
Proc.Natl.Acad.Sci.USA, 108, 2011
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2YVC
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7BYJ
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6QLY
 | | IDOL FERM domain | | 分子名称: | 1,2-ETHANEDIOL, E3 ubiquitin-protein ligase MYLIP, SULFATE ION | | 著者 | Martinelli, L, Sixma, T.K. | | 登録日 | 2019-02-01 | | 公開日 | 2020-02-19 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Structural analysis of the LDL receptor-interacting FERM domain in the E3 ubiquitin ligase IDOL reveals an obscured substrate-binding site.
J.Biol.Chem., 295, 2020
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8FSE
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8FTB
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8GVL
 | | PTPN21 FERM | | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, Tyrosine-protein phosphatase non-receptor type 21 | | 著者 | Chen, L, Zheng, Y.Y, Zhou, C. | | 登録日 | 2022-09-15 | | 公開日 | 2023-09-20 | | 最終更新日 | 2024-04-17 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Structural analysis of PTPN21 reveals a dominant-negative effect of the FERM domain on its phosphatase activity.
Sci Adv, 10, 2024
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2AEH
 | | Focal adhesion kinase 1 | | 分子名称: | Focal adhesion kinase 1 | | 著者 | Ceccarelli, D.F, Song, H.K, Poy, F, Schaller, M.D, Eck, M.J. | | 登録日 | 2005-07-22 | | 公開日 | 2005-10-18 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.53 Å) | | 主引用文献 | Crystal Structure of the FERM Domain of Focal Adhesion Kinase
J.Biol.Chem., 281, 2006
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6R9T
 | | Cryo-EM structure of autoinhibited human talin-1 | | 分子名称: | Talin-1 | | 著者 | Dedden, D, Schumacher, S, Zacharias, M, Biertumpfel, C, Mizuno, N. | | 登録日 | 2019-04-04 | | 公開日 | 2019-10-16 | | 最終更新日 | 2024-05-22 | | 実験手法 | ELECTRON MICROSCOPY (6.2 Å) | | 主引用文献 | The Architecture of Talin1 Reveals an Autoinhibition Mechanism.
Cell, 179, 2019
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1Y19
 | | Structural basis for phosphatidylinositol phosphate kinase type I-gamma binding to talin at focal adhesions | | 分子名称: | Phosphatidylinositol-4-phosphate 5-kinase, type 1 gamma, Talin 1 | | 著者 | de Pereda, J.M, Wegener, K, Santelli, E, Bate, N, Ginsberg, M.H, Critchley, D.R, Campbell, I.D, Liddington, R.C. | | 登録日 | 2004-11-17 | | 公開日 | 2005-01-04 | | 最終更新日 | 2016-11-30 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Structural bases for phosphatidylinositol phosphate kinase type I-gamma binding to talin at focal adhesions
J.Biol.Chem., 280, 2005
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7EDR
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2AL6
 | | FERM domain of Focal Adhesion Kinase | | 分子名称: | Focal adhesion kinase 1 | | 著者 | Ceccarelli, D.F, Song, H.K, Poy, F, Schaller, M.D, Eck, M.J. | | 登録日 | 2005-08-04 | | 公開日 | 2005-10-18 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | | 主引用文献 | Crystal Structure of the FERM Domain of Focal Adhesion Kinase
J.Biol.Chem., 281, 2006
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