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9EY5
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Crystal structure of human tyrosinase-related protein 1 (TYRP1) in complex with (S)-2,4-dihydroxyphenylalanine
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-hydroxy-L-tyrosine, ...
著者Ng, Y.M, Soler-Lopez, M.
登録日2024-04-09
公開日2024-05-22
最終更新日2024-07-03
実験手法X-RAY DIFFRACTION (2.61 Å)
主引用文献Interactions of Phenylalanine Derivatives with Human Tyrosinase: Lessons from Experimental and Theoretical tudies.
Chembiochem, 25, 2024
9EY6
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BU of 9ey6 by Molmil
Crystal structure of human tyrosinase-related protein 1 (TYRP1)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, 5,6-dihydroxyindole-2-carboxylic acid oxidase, ...
著者Ng, Y.M, Soler-Lopez, M.
登録日2024-04-09
公開日2024-05-22
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (2.228 Å)
主引用文献Interactions of Phenylalanine Derivatives with Human Tyrosinase: Lessons from Experimental and Theoretical tudies.
Chembiochem, 25, 2024
9EY7
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BU of 9ey7 by Molmil
Crystal structure of human tyrosinase-related protein 1 (TYRP1) in complex with (R)-2,4-dihydroxyphenylalanine
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-hydroxy-L-tyrosine, ...
著者Ng, Y.M, Soler-Lopez, M.
登録日2024-04-09
公開日2024-05-22
最終更新日2024-07-03
実験手法X-RAY DIFFRACTION (2.61 Å)
主引用文献Interactions of Phenylalanine Derivatives with Human Tyrosinase: Lessons from Experimental and Theoretical tudies.
Chembiochem, 25, 2024
9EY8
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BU of 9ey8 by Molmil
Crystal structure of human tyrosinase-related protein 1 (TYRP1) in complex with (s)-amino-L-tyrosine
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Ng, Y.M, Soler-Lopez, M.
登録日2024-04-09
公開日2024-05-01
最終更新日2024-07-03
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Interactions of Phenylalanine Derivatives with Human Tyrosinase: Lessons from Experimental and Theoretical tudies.
Chembiochem, 25, 2024
8HPI
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BU of 8hpi by Molmil
Crystal structure of Tyrosinase from Priestia megaterium
分子名称: 1,2-ETHANEDIOL, Tyrosinase, ZINC ION
著者Huang, Y, Song, W.
登録日2022-12-12
公開日2023-12-13
実験手法X-RAY DIFFRACTION (2.54 Å)
主引用文献Crystal structure of Tyrosinase from Priestia megaterium
To Be Published
8B74
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BU of 8b74 by Molmil
Tyrosinase from halophilic bacterium Hahella sp. CCB MM4
分子名称: Oxidoreductase
著者Rohr, A.K, Santos, G.A, Englund, A.N.
登録日2022-09-28
公開日2023-10-11
実験手法X-RAY DIFFRACTION (1.965 Å)
主引用文献Tyrosinase from halophilic bacterium Hahella sp. CCB MM4
To Be Published
7XIO
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BU of 7xio by Molmil
Crystal structure of TYR from Ralstonia
分子名称: PHOSPHATE ION, Polyphenol oxidase
著者Sun, D.Y, Cui, P.P, Liao, L.J, Liu, X.K, Liu, B, Guo, Y, Feng, Z, Zhang, J, Li, X, Zeng, Z.X.
登録日2022-04-13
公開日2023-04-19
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.64 Å)
主引用文献Crystal structure of TYR from Ralstonia
To Be Published
7CIT
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BU of 7cit by Molmil
Crystal structure of tyrosinase from Streptomyces castaneoglobisporus in complex with the caddie protein obtained by soaking in the solution containing Cu(II) and hydroxylamine for 24 h
分子名称: COPPER (II) ION, HYDROGEN PEROXIDE, MelC, ...
著者Oda, K, Matoba, Y.
登録日2020-07-08
公開日2021-06-16
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献The basicity of an active-site water molecule discriminates between tyrosinase and catechol oxidase activity.
Int.J.Biol.Macromol., 183, 2021
7CIY
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BU of 7ciy by Molmil
Crystal structure of N191G-mutated tyrosinase from Streptomyces castaneoglobisporus in complex with the caddie protein obtained by soaking in the solution containing Cu(II) and hydroxylamine for 24 h
分子名称: COPPER (II) ION, HYDROGEN PEROXIDE, MelC, ...
著者Oda, K, Matoba, Y.
登録日2020-07-08
公開日2021-06-16
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.47 Å)
主引用文献The basicity of an active-site water molecule discriminates between tyrosinase and catechol oxidase activity.
Int.J.Biol.Macromol., 183, 2021
6Z1S
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BU of 6z1s by Molmil
Structure of Polyphenol Oxidase (mutant G292N) from Thermothelomyces thermophila
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Dimarogona, M, Nikolaivits, E, Valmas, A, Topakas, E.
登録日2020-05-14
公開日2021-03-24
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.53 Å)
主引用文献Considerations Regarding Activity Determinants of Fungal Polyphenol Oxidases Based on Mutational and Structural Studies.
Appl.Environ.Microbiol., 87, 2021
6JUD
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BU of 6jud by Molmil
Radiation damage in Aspergillus oryzae pro-tyrosinase oxygen-bound C92A/H103F mutant
分子名称: COPPER (II) ION, PEROXIDE ION, Tyrosinase
著者Fujieda, N, Umakoshi, K, Nishikawa, Y, Kurisu, G, Itoh, S.
登録日2019-04-13
公開日2020-05-13
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.56 Å)
主引用文献Copper-Oxygen Dynamics in the Tyrosinase Mechanism.
Angew.Chem.Int.Ed.Engl., 59, 2020
6JU6
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BU of 6ju6 by Molmil
Aspergillus oryzae active-tyrosinase copper-depleted C92A mutant
分子名称: NITRATE ION, Tyrosinase
著者Fujieda, N, Umakoshi, K, Nishikawa, Y, Kurisu, G, Itoh, S.
登録日2019-04-13
公開日2020-05-13
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Copper-Oxygen Dynamics in the Tyrosinase Mechanism.
Angew.Chem.Int.Ed.Engl., 59, 2020
6JUC
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BU of 6juc by Molmil
Aspergillus oryzae pro-tyrosinase oxygen-bound C92A/H103F mutant
分子名称: COPPER (II) ION, PEROXIDE ION, Tyrosinase
著者Fujieda, N, Umakoshi, K, Nishikawa, Y, Kurisu, G, Itoh, S.
登録日2019-04-13
公開日2020-05-13
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.44 Å)
主引用文献Copper-Oxygen Dynamics in the Tyrosinase Mechanism.
Angew.Chem.Int.Ed.Engl., 59, 2020
6JU5
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BU of 6ju5 by Molmil
Aspergillus oryzae pro-tyrosinase C92A/F513Y mutant
分子名称: COPPER (II) ION, Tyrosinase
著者Fujieda, N, Umakoshi, K, Nishikawa, Y, Kurisu, G, Itoh, S.
登録日2019-04-13
公開日2020-05-13
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.34 Å)
主引用文献Copper-Oxygen Dynamics in the Tyrosinase Mechanism.
Angew.Chem.Int.Ed.Engl., 59, 2020
6JU9
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BU of 6ju9 by Molmil
Aspergillus oryzae active-tyrosinase copper-bound C92A mutant complexed with L-tyrosine
分子名称: 3,4-DIHYDROXYPHENYLALANINE, COPPER (II) ION, NITRATE ION, ...
著者Fujieda, N, Umakoshi, K, Nishikawa, Y, Kurisu, G, Itoh, S.
登録日2019-04-13
公開日2020-05-13
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.42 Å)
主引用文献Copper-Oxygen Dynamics in the Tyrosinase Mechanism.
Angew.Chem.Int.Ed.Engl., 59, 2020
6JU7
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BU of 6ju7 by Molmil
Aspergillus oryzae active-tyrosinase copper-depleted C92A mutant complexed with L-tyrosine
分子名称: NITRATE ION, TYROSINE, Tyrosinase
著者Fujieda, N, Umakoshi, K, Nishikawa, Y, Kurisu, G, Itoh, S.
登録日2019-04-13
公開日2020-05-13
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.42 Å)
主引用文献Copper-Oxygen Dynamics in the Tyrosinase Mechanism.
Angew.Chem.Int.Ed.Engl., 59, 2020
6JUA
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BU of 6jua by Molmil
Aspergillus oryzae pro-tyrosinase oxygen-bound C92A mutant
分子名称: COPPER (II) ION, PEROXIDE ION, Tyrosinase
著者Fujieda, N, Umakoshi, K, Nishikawa, Y, Kurisu, G, Itoh, S.
登録日2019-04-13
公開日2020-05-13
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.45 Å)
主引用文献Copper-Oxygen Dynamics in the Tyrosinase Mechanism.
Angew.Chem.Int.Ed.Engl., 59, 2020
6JU4
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BU of 6ju4 by Molmil
Aspergillus oryzae pro-tyrosinase F513Y mutant
分子名称: COPPER (II) ION, Tyrosinase
著者Fujieda, N, Umakoshi, K, Nishikawa, Y, Kurisu, G, Itoh, S.
登録日2019-04-13
公開日2020-05-13
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.35 Å)
主引用文献Copper-Oxygen Dynamics in the Tyrosinase Mechanism.
Angew.Chem.Int.Ed.Engl., 59, 2020
6JU8
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BU of 6ju8 by Molmil
Aspergillus oryzae active-tyrosinase copper-bound C92A mutant
分子名称: COPPER (II) ION, NITRATE ION, Tyrosinase
著者Fujieda, N, Umakoshi, K, Nishikawa, Y, Kurisu, G, Itoh, S.
登録日2019-04-13
公開日2020-05-13
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.27 Å)
主引用文献Copper-Oxygen Dynamics in the Tyrosinase Mechanism.
Angew.Chem.Int.Ed.Engl., 59, 2020
6JUB
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BU of 6jub by Molmil
Radiation damage in Aspergillus oryzae pro-tyrosinase oxygen-bound C92A mutant
分子名称: COPPER (II) ION, PEROXIDE ION, Tyrosinase
著者Fujieda, N, Umakoshi, K, Nishikawa, Y, Kurisu, G, Itoh, S.
登録日2019-04-13
公開日2020-05-13
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.54 Å)
主引用文献Copper-Oxygen Dynamics in the Tyrosinase Mechanism.
Angew.Chem.Int.Ed.Engl., 59, 2020
6J2U
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BU of 6j2u by Molmil
Crystal structure of Tyrosinase caddy protein(MelC1)with Tyrosinase (MelC2)from Streptomyces avermitilis in complex with Zinc ion
分子名称: Tyrosinase, Tyrosinase co-factor protein, ZINC ION
著者Lee, S.-H, Hong, H, Kim, K.-J.
登録日2019-01-03
公開日2020-02-12
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.3 Å)
主引用文献Crystal structure of Tyrosinase caddy protein(MelC1)with tyrosinase (MelC2)from Streptomyces avermitilis in complex with Zinc ion
To Be Published
6QXD
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BU of 6qxd by Molmil
Crystal Structure of tyrosinase from Bacillus megaterium with JKB inhibitor in the active site.
分子名称: (2,4-dinitrophenyl)-[4-[(4-fluorophenyl)methyl]piperazin-1-yl]methanone, COPPER (II) ION, Tyrosinase
著者Deri Zenaty, B, Gitto, R, Pazy, Y, Fishman, A.
登録日2019-03-07
公開日2019-06-19
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.317 Å)
主引用文献Exploiting the 1-(4-fluorobenzyl)piperazine fragment for the development of novel tyrosinase inhibitors as anti-melanogenic agents: Design, synthesis, structural insights and biological profile.
Eur.J.Med.Chem., 178, 2019
6R83
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BU of 6r83 by Molmil
CryoEM structure and molecular model of squid hemocyanin (Todarodes pacificus , TpH)
分子名称: Hemocyanin subunit 1
著者Tanaka, Y, Kato, S, Stabrin, M, Raunser, S, Matsui, T, Gatsogiannis, C.
登録日2019-03-31
公開日2019-05-08
最終更新日2024-05-22
実験手法ELECTRON MICROSCOPY (5.1 Å)
主引用文献Cryo-EM reveals the asymmetric assembly of squid hemocyanin.
Iucrj, 6, 2019
6ELS
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BU of 6els by Molmil
Structure of latent apple tyrosinase (MdPPO1)
分子名称: COPPER (II) ION, OXYGEN ATOM, Polyphenol oxidase, ...
著者Kampatsikas, I, Bijelic, A, Pretzler, M, Rompel, A.
登録日2017-09-29
公開日2019-03-20
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (1.346 Å)
主引用文献A Peptide-Induced Self-Cleavage Reaction Initiates the Activation of Tyrosinase.
Angew.Chem.Int.Ed.Engl., 58, 2019
6HQJ
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BU of 6hqj by Molmil
apo-form of polyphenol oxidase from Solanum lycopersicum
分子名称: Polyphenol oxidase A, chloroplastic
著者Kampatsikas, I, Bijelic, A, Rompel, A.
登録日2018-09-25
公開日2019-03-20
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (1.802 Å)
主引用文献Biochemical and structural characterization of tomato polyphenol oxidases provide novel insights into their substrate specificity.
Sci Rep, 9, 2019

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件を2024-10-16に公開中

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