PDB: 150 件ウェブページステータス検索Chemie searchBIRD

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2FGF	THREE-DIMENSIONAL STRUCTURE OF HUMAN BASIC FIBROBLAST GROWTH FACTOR, A STRUCTURAL HOMOLOG OF INTERLEUKIN 1BETA 分子名称: HEPARIN-BINDING GROWTH FACTOR 2 PRECURSOR, SULFATE ION 著者 Zhang, J, Sprang, S.R. 登録日 1991-02-19 公開日 1992-01-15 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (1.77 Å) 主引用文献 Three-dimensional structure of human basic fibroblast growth factor, a structural homolog of interleukin 1 beta. Proc.Natl.Acad.Sci.USA, 88, 1991
3UD7	Crystal Structure Analysis of FGF1-Disaccharide(NI21) complexes 分子名称: 2-deoxy-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-1-O-methyl-2-O-sulfo-alpha-L-idopyranuronic acid, Heparin-binding growth factor 1, PHOSPHATE ION 著者 Hung, S.-C, Shi, Z. 登録日 2011-10-27 公開日 2012-11-28 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Divergent synthesis of 48 heparan sulfate-based disaccharides and probing the specific sugar-fibroblast growth factor-1 interaction J.Am.Chem.Soc., 134, 2012
5X1O	PI(4,5)P2 lipid binding induced a reorientation of FGF2 molecules near membrane surface to facilitate the unconventional oligomerization-dependent secretion process as revealed by a combined FTIR/NMR/X-ray study 分子名称: D-MYO-INOSITOL-1,4,5-TRIPHOSPHATE, Fibroblast growth factor 2 著者 Tsao, Y.H. 登録日 2017-01-26 公開日 2018-03-07 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 PI(4,5)P2 lipid binding induced a reorientation of FGF2 molecules near membrane surface to facilitate the unconventional oligomerization-dependent secretion process as revealed by a combined FTIR/NMR/X-ray study To Be Published
4XKI	Human Fibroblast Growth Factor - 1 (FGF-1) mutant S116R 分子名称: Fibroblast growth factor 1, GLYCEROL, NONAETHYLENE GLYCOL, ... 著者 Xia, X. 登録日 2015-01-12 公開日 2016-01-20 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Biophysical characterizations of Fibroblast Growth Factor - 1 mutant with increased heparin binding affinity To Be Published
1FGA	REFINEMENT OF THE STRUCTURE OF HUMAN BASIC FIBROBLAST GROWTH FACTOR AT 1.6 ANGSTROMS RESOLUTION AND ANALYSIS OF PRESUMED HEPARIN BINDING SITES BY SELENATE SUBSTITUTION 分子名称: BASIC FIBROBLAST GROWTH FACTOR, BETA-MERCAPTOETHANOL, SELENATE ION 著者 Eriksson, A.E, Matthews, B.W. 登録日 1993-02-26 公開日 1993-07-15 最終更新日 2020-07-22 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Refinement of the structure of human basic fibroblast growth factor at 1.6 A resolution and analysis of presumed heparin binding sites by selenate substitution. Protein Sci., 2, 1993
8OM6	Crystal structure of FGF2-STAB, a stable variant of human fibroblast growth factor 2 分子名称: Fibroblast growth factor 2 著者 Marek, M, Chaloupkova, R, de La Bourdonnaye, G. 登録日 2023-03-31 公開日 2024-03-06 実験手法 X-RAY DIFFRACTION (1.31 Å) 主引用文献 Crystal structure of FGF2-STAB, a stable variant of human fibroblast growth factor 2 To Be Published
4YOL	Human fibroblast growth factor-1 C16S/A66C/C117A/P134A 分子名称: CITRATE ANION, Fibroblast growth factor 1, IMIDAZOLE 著者 Xia, X, Blaber, M. 登録日 2015-03-11 公開日 2016-03-16 最終更新日 2019-02-13 実験手法 X-RAY DIFFRACTION (1.97 Å) 主引用文献 Engineering a Cysteine-Free Form of Human Fibroblast Growth Factor-1 for "Second Generation" Therapeutic Application. J.Pharm.Sci., 105, 2016
4FGF	REFINEMENT OF THE STRUCTURE OF HUMAN BASIC FIBROBLAST GROWTH FACTOR AT 1.6 ANGSTROMS RESOLUTION AND ANALYSIS OF PRESUMED HEPARIN BINDING SITES BY SELENATE SUBSTITUTION 分子名称: BASIC FIBROBLAST GROWTH FACTOR, BETA-MERCAPTOETHANOL, SULFATE ION 著者 Eriksson, A.E, Matthews, B.W. 登録日 1993-02-26 公開日 1993-07-15 最終更新日 2017-11-29 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Refinement of the structure of human basic fibroblast growth factor at 1.6 A resolution and analysis of presumed heparin binding sites by selenate substitution. Protein Sci., 2, 1993
6KTR	Crystal structure of fibroblast growth factor 19 in complex with Fab 分子名称: Fibroblast growth factor 19, G1A8-Fab-HC, G1A8-Fab-LC, ... 著者 Liu, H, Zheng, S, Hou, X, Liu, X, Lv, X, Li, Y, Li, W, Sui, J. 登録日 2019-08-28 公開日 2020-07-08 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.59775758 Å) 主引用文献 Novel Abs targeting the N-terminus of fibroblast growth factor 19 inhibit hepatocellular carcinoma growth without bile-acid-related side-effects. Cancer Sci., 111, 2020
6M6F	Solution structure of disulfide bond mutaion of the core domain of Fibroblast growth factor 21 (FGF21) 分子名称: Fibroblast growth factor 21 著者 Zhu, L, Zhao, H, Wang, J. 登録日 2020-03-14 公開日 2021-01-20 最終更新日 2023-06-14 実験手法 SOLUTION NMR 主引用文献 Dynamic folding modulation generates FGF21 variant against diabetes. Embo Rep., 22, 2021
6M6E	Solution structure of the core domain of Fibroblast growth factor 21 (FGF21) 分子名称: Fibroblast growth factor 21 著者 Zhu, L, Zhao, H, Wang, J. 登録日 2020-03-14 公開日 2021-01-20 最終更新日 2023-06-14 実験手法 SOLUTION NMR 主引用文献 Dynamic folding modulation generates FGF21 variant against diabetes. Embo Rep., 22, 2021
2RQ9	Solution structure of human acidic fibroblast growth factor (aFGF) in the presence of a protein stabilizer NDSB-new 分子名称: Heparin-binding growth factor 1 著者 Enomoto, M, Xiang, L, Ishii, T, Tochio, N, Hosoda, K, Inoue, Y, Nameki, N, Wakamatsu, K. 登録日 2009-03-12 公開日 2010-03-16 最終更新日 2024-05-29 実験手法 SOLUTION NMR 主引用文献 Solution structure of human acidic fibroblast growth factor (aFGF) in the presence of a protein stabilizer NDSB-new To be Published
4CJM	Crystal structure of human FGF18 分子名称: FIBROBLAST GROWTH FACTOR 18, SULFATE ION 著者 Brown, A, Adam, L.E, Blundell, T.L. 登録日 2013-12-21 公開日 2014-04-09 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 The Crystal Structure of Fibroblast Growth Factor 18 (Fgf18) Protein Cell, 5, 2014
2UUS	Crystal structure of the rat FGF1-sucrose octasulfate (SOS) complex. 分子名称: 1,3,4,6-tetra-O-sulfo-beta-D-fructofuranose-(2-1)-2,3,4,6-tetra-O-sulfonato-alpha-D-glucopyranose, HEPARIN-BINDING GROWTH FACTOR 1 著者 Kulahin, N, Kiselyov, V, Kochoyan, A, Kristensen, O, Berezin, V, Bock, E, Gajhede, M. 登録日 2007-03-07 公開日 2008-05-13 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Dimerization Effect of Sucrose Octasulfate on Rat Fgf1. Acta Crystallogr.,Sect.F, 64, 2008
1FMM	SOLUTION STRUCTURE OF NFGF-1 分子名称: ACIDIC FIBROBLAST GROWTH FACTOR 著者 Arunkumar, A.I, Srisailam, S, Kumar, T.K.S, Chiu, I.M, Yu, C. 登録日 2000-08-18 公開日 2001-08-18 最終更新日 2024-05-22 実験手法 SOLUTION NMR 主引用文献 Structure and stability of an acidic fibroblast growth factor from Notophthalmus viridescens. J.Biol.Chem., 277, 2002
3UD8	Crystal Structure Analysis of FGF1-Disaccharide(NI22) complex 分子名称: 2-deoxy-3-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-1-O-methyl-2-O-sulfo-alpha-L-idopyranuronic acid, Heparin-binding growth factor 1, PHOSPHATE ION 著者 Hung, S.-C, Shi, Z. 登録日 2011-10-27 公開日 2012-11-28 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.37 Å) 主引用文献 Divergent synthesis of 48 heparan sulfate-based disaccharides and probing the specific sugar-fibroblast growth factor-1 interaction J.Am.Chem.Soc., 134, 2012
3UDA	Crystal Structure Analysis of FGF1-Disaccharide(NI24) complex 分子名称: 2-deoxy-3,6-di-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-1-O-methyl-2-O-sulfo-alpha-L-idopyranuronic acid, Heparin-binding growth factor 1, PHOSPHATE ION 著者 Hung, S.-C, Shi, Z. 登録日 2011-10-27 公開日 2012-11-28 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (2.51 Å) 主引用文献 Divergent synthesis of 48 heparan sulfate-based disaccharides and probing the specific sugar-fibroblast growth factor-1 interaction J.Am.Chem.Soc., 134, 2012
3UD9	Crystal Structure Analysis of FGF1-Disaccharide(NI23) complex 分子名称: 2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-1-O-methyl-2-O-sulfo-alpha-L-idopyranuronic acid, Heparin-binding growth factor 1, PHOSPHATE ION 著者 Hung, S.-C, Shi, Z. 登録日 2011-10-27 公開日 2012-11-28 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.34 Å) 主引用文献 Divergent synthesis of 48 heparan sulfate-based disaccharides and probing the specific sugar-fibroblast growth factor-1 interaction J.Am.Chem.Soc., 134, 2012
1G82	STRUCTURE OF FIBROBLAST GROWTH FACTOR 9 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, FIBROBLAST GROWTH FACTOR 9, ... 著者 Hecht, H.J, Adar, R, Hofmann, B, Bogin, O, Weich, H, Yayon, A. 登録日 2000-11-16 公開日 2001-03-07 最終更新日 2023-08-09 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Structure of fibroblast growth factor 9 shows a symmetric dimer with unique receptor- and heparin-binding interfaces. Acta Crystallogr.,Sect.D, 57, 2001
1RG8	Human Acidic Fibroblast Growth Factor (haFGF-1) at 1.10 angstrom resolution (140 amino acid form) 分子名称: FORMIC ACID, Heparin-binding growth factor 1 著者 Bernett, M.J, Somasundaram, T, Blaber, M. 登録日 2003-11-11 公開日 2004-10-05 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (1.1 Å) 主引用文献 An atomic resolution structure for human fibroblast growth factor 1. Proteins, 57, 2004
1RML	NMR STUDY OF ACID FIBROBLAST GROWTH FACTOR BOUND TO 1,3,6-NAPHTHALENE TRISULPHONATE, 26 STRUCTURES 分子名称: ACIDIC FIBROBLAST GROWTH FACTOR, NAPHTHALENE TRISULFONATE 著者 Lozano, R.M, Jimenez, M.A, Santoro, J, Rico, M, Gimenez-Gallego, G. 登録日 1998-05-21 公開日 1998-11-11 最終更新日 2024-05-22 実験手法 SOLUTION NMR 主引用文献 Solution structure of acidic fibroblast growth factor bound to 1,3, 6-naphthalenetrisulfonate: a minimal model for the anti-tumoral action of suramins and suradistas. J.Mol.Biol., 281, 1998
2BFH	CRYSTAL STRUCTURE OF BASIC FIBROBLAST GROWTH FACTOR AT 1.6 ANGSTROMS RESOLUTION 分子名称: BASIC FIBROBLAST GROWTH FACTOR 著者 Kitagawa, Y, Ago, H, Katsube, Y, Fujishima, A, Matsuura, Y. 登録日 1993-08-31 公開日 1994-01-31 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Crystal structure of basic fibroblast growth factor at 1.6 A resolution. J.Biochem.(Tokyo), 110, 1991
3O3Q	Crystal structure of "L44F/M67I/L73V/A103G/deletion 104-106/F108Y/V109L/L111I/C117V/R119G/deletion 120-122" mutant form of Human acidic fibroblast growth factor 分子名称: GLYCEROL, Heparin-binding growth factor 1 著者 Lee, J, Blaber, M. 登録日 2010-07-25 公開日 2011-02-23 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 A polypeptide "building block"top-down symmetric deconstruction". J.Mol.Biol., 407, 2011
2AQZ	Crystal structure of FGF-1, S17T/N18T/G19 deletion mutant 分子名称: Heparin-binding growth factor 1, SULFATE ION 著者 Lee, J, Blaber, M. 登録日 2005-08-18 公開日 2006-02-07 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Conversion of type I 4:6 to 3:5 beta-turn types in human acidic fibroblast growth factor: Effects upon structure, stability, folding, and mitogenic function. Proteins, 62, 2006
2ERM	Solution structure of a biologically active human FGF-1 monomer, complexed to a hexasaccharide heparin-analogue 分子名称: 2-deoxy-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-acetamido-2-deoxy-6-O-sulfo-alpha-D-glucopyranose-(1-4)-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid, Heparin-binding growth factor 1, ISOPROPYL ALCOHOL 著者 Canales, A, Lozano, R, Nieto, P.M, Martin-Lomas, M, Gimenez-Gallego, G, Jimenez-Barbero, J. 登録日 2005-10-25 公開日 2006-10-03 最終更新日 2024-05-01 実験手法 SOLUTION NMR 主引用文献 Solution NMR structure of a human FGF-1 monomer, activated by a hexasaccharide heparin-analogue. Febs J., 273, 2006

 

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