PDB: 513 件ウェブページステータス検索Chemie searchBIRD

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7SZP	Crystal Structure of Histidinol-phosphate aminotransferase from Klebsiella pneumoniae subsp. pneumoniae (strain HS11286) 分子名称: 1,2-ETHANEDIOL, ACETATE ION, CALCIUM ION, ... 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2021-11-29 公開日 2021-12-15 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Crystal Structure of Histidinol-phosphate aminotransferase from Klebsiella pneumoniae subsp. pneumoniae (strain HS11286) to be published
9AAT	X-RAY STRUCTURE REFINEMENT AND COMPARISON OF THREE FORMS OF MITOCHONDRIAL ASPARTATE AMINOTRANSFERASE 分子名称: 4'-DEOXY-4'-AMINOPYRIDOXAL-5'-PHOSPHATE, ASPARTATE AMINOTRANSFERASE 著者 Mcphalen, C.A, Vincent, M.G, Jansonius, J.N. 登録日 1991-12-02 公開日 1993-10-31 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 X-ray structure refinement and comparison of three forms of mitochondrial aspartate aminotransferase. J.Mol.Biol., 225, 1992
6ONN	Crystal structure of 8-amino-7-oxononanoate synthase from Burkholderia phymatum 分子名称: 8-amino-7-oxononanoate synthase 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2019-04-22 公開日 2019-05-01 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Crystal structure of 8-amino-7-oxononanoate synthase from Burkholderia phymatum To be published
6UXZ	(S)-4-Amino-5-phenoxypentanoate as a Selective Agonist of the Transcription Factor GabR 分子名称: (4S)-4-[(E)-({3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methylidene)amino]-5-phenoxypentanoic acid, HTH-type transcriptional regulatory protein GabR, SULFATE ION 著者 Catlin, D.S, Liu, D. 登録日 2019-11-09 公開日 2020-10-07 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 (S)-4-Amino-5-phenoxypentanoate designed as a potential selective agonist of the bacterial transcription factor GabR. Protein Sci., 29, 2020
7N79	O2-, PLP-dependent desaturase Plu4 holo-enzyme 分子名称: 1,2-ETHANEDIOL, 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ACETATE ION, ... 著者 Hoffarth, E.R, Ryan, K.S. 登録日 2021-06-09 公開日 2021-10-06 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (1.98 Å) 主引用文献 A shared mechanistic pathway for pyridoxal phosphate-dependent arginine oxidases. Proc.Natl.Acad.Sci.USA, 118, 2021
8SKR	human liver mitochondrial Aspartate aminotransferase 分子名称: Aspartate aminotransferase, mitochondrial, PYRIDOXAL-5'-PHOSPHATE 著者 Zhang, Z, Tringides, M. 登録日 2023-04-20 公開日 2024-02-21 実験手法 ELECTRON MICROSCOPY (2.99 Å) 主引用文献 High-Resolution Structural Proteomics of Mitochondria Using the 'Build and Retrieve' Methodology. Mol.Cell Proteomics, 22, 2023
5JAY	Crystal Structure of an 8-amino-7-oxononanoate Synthase from Burkholderia xenovorans 分子名称: 8-amino-7-oxononanoate synthase 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2016-04-12 公開日 2016-04-20 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Crystal Structure of an 8-amino-7-oxononanoate Synthase from Burkholderia xenovorans to be published
4M2M	Crystal structure of PLP-dependent cyclase OrfR in complex with PLP-L-Arg 分子名称: ARGININE, Aminotransferase, PYRIDOXAL-5'-PHOSPHATE 著者 Chang, C.Y, Liu, Y.C, Lyu, S.Y, Wu, C.C, Li, T.L. 登録日 2013-08-05 公開日 2014-06-18 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.58 Å) 主引用文献 Biosynthesis of streptolidine involved two unexpected intermediates produced by a dihydroxylase and a cyclase through unusual mechanisms. Angew.Chem.Int.Ed.Engl., 53, 2014
4CVQ	CRYSTAL STRUCTURE OF AN AMINOTRANSFERASE FROM ESCHERICHIA COLI AT 2. 11 ANGSTROEM RESOLUTION 分子名称: ACETATE ION, GLUTAMATE-PYRUVATE AMINOTRANSFERASE ALAA, GLYCEROL, ... 著者 Penya-Soler, E, Fernandez, F.J, Lopez-Estepa, M, Garces, F, Richardson, A.J, Rudd, K.E, Coll, M, Vega, M.C. 登録日 2014-03-28 公開日 2014-07-23 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.11 Å) 主引用文献 Structural analysis and mutant growth properties reveal distinctive enzymatic and cellular roles for the three major L-alanine transaminases of Escherichia coli. PLoS ONE, 9, 2014
4WB0	Crystal structure of the broad specificity aminotransferase from Leishmania mexicana 分子名称: Broad specificity aminotransferase, CACODYLATE ION 著者 Wen, J, Nowicki, C, Blankenfeldt, W. 登録日 2014-09-02 公開日 2015-09-09 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.91 Å) 主引用文献 Structural basis for the relaxed substrate selectivity of Leishmania mexicana broad specificity aminotransferase. Mol.Biochem.Parasitol., 202, 2015
6QP3	Crystal structure of the PLP-bound C-S lyase from Bacillus subtilis (strain 168) 分子名称: ACETATE ION, Cystathionine beta-lyase PatB, PYRIDOXAL-5'-PHOSPHATE 著者 Herman, R, Rudden, M, Wilkinson, A.J, Hanai, S, Thomas, G.H. 登録日 2019-02-13 公開日 2020-03-04 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 The molecular basis of thioalcohol production in human body odour. Sci Rep, 10, 2020
4W5K	Structure of a mitochondrial aspartate aminotransferase from Trypanosoma brucei, K237A mutant 分子名称: 1,2-ETHANEDIOL, Aspartate aminotransferase, mitochondrial, ... 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2014-08-18 公開日 2014-09-24 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Structures of aspartate aminotransferases from Trypanosoma brucei, Leishmania major and Giardia lamblia. Acta Crystallogr.,Sect.F, 71, 2015
5VWQ	E.coli Aspartate aminotransferase-(1R,3S,4S)-3-amino-4-fluorocyclopentane-1-carboxylic acid (FCP) 分子名称: 4'-DEOXY-4'-AMINOPYRIDOXAL-5'-PHOSPHATE, Aspartate aminotransferase 著者 Mascarenhas, R, Lehrer, H, Liu, D, Ringe, D. 登録日 2017-05-22 公開日 2017-08-30 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Selective Targeting by a Mechanism-Based Inactivator against Pyridoxal 5'-Phosphate-Dependent Enzymes: Mechanisms of Inactivation and Alternative Turnover. Biochemistry, 56, 2017
5VNX	Crystal structure of an 8-amino-7-oxononanoate synthase from Burkholderia multivorans with a potential glycine-PLP-Lys242 cyclized intermediate or byproduct 分子名称: 1,2-ETHANEDIOL, 8-amino-7-oxononanoate synthase, BENZAMIDINE, ... 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2017-05-01 公開日 2017-05-17 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 Crystal structure of a 8-amino-7-oxononanoate synthase from Burkholderia multivorans with a potential glycine-PLP-Lys242 cyclized intermediate or byproduct to be published
4DBC	Substrate Activation in Aspartate Aminotransferase 分子名称: (E)-N-{2-hydroxy-3-methyl-6-[(phosphonooxy)methyl]benzylidene}-L-aspartic acid, 1,2-ETHANEDIOL, Aspartate aminotransferase, ... 著者 Toney, M.D, Fisher, A.J, Griswold, W.R. 登録日 2012-01-14 公開日 2012-12-05 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Ground-state electronic destabilization via hyperconjugation in aspartate aminotransferase. J.Am.Chem.Soc., 134, 2012
1YIY	Aedes aegypti kynurenine aminotransferase 分子名称: 4'-DEOXY-4'-AMINOPYRIDOXAL-5'-PHOSPHATE, BROMIDE ION, kynurenine aminotransferase; glutamine transaminase K 著者 Han, Q, Gao, Y.G, Robinson, H, Ding, H, Wilson, S, Li, J. 登録日 2005-01-13 公開日 2005-05-10 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Crystal structures of Aedes aegypti kynurenine aminotransferase. FEBS J., 272, 2005
1YIZ	Aedes aegypti kynurenine aminotrasferase 分子名称: BROMIDE ION, kynurenine aminotransferase; glutamine transaminase 著者 Han, Q, Gao, Y.G, Robinson, H, Ding, H, Wilson, S, Li, J. 登録日 2005-01-13 公開日 2005-05-10 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.55 Å) 主引用文献 Crystal structures of Aedes aegypti kynurenine aminotransferase. FEBS J., 272, 2005
6S8W	Aromatic aminotransferase AroH (Aro8) form Aspergillus fumigatus in complex with PLP (internal aldimine) 分子名称: Aromatic aminotransferase Aro8, putative, FORMIC ACID, ... 著者 Giardina, G, Mirco, D, Spizzichino, S, Zelante, T, Cutruzzola, F, Romani, L, Cellini, B. 登録日 2019-07-10 公開日 2020-08-26 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Crystal structure of Aspergillus fumigatus AroH, an aromatic amino acid aminotransferase Proteins, 2021
5EAA	ASPARTATE AMINOTRANSFERASE FROM E. COLI, C191S MUTATION 分子名称: ASPARTATE AMINOTRANSFERASE, PYRIDOXAL-5'-PHOSPHATE 著者 Jeffery, C.J, Gloss, L.M, Petsko, G.A, Ringe, D. 登録日 1998-12-29 公開日 2000-10-27 最終更新日 2023-08-09 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 The role of residues outside the active site: structural basis for function of C191 mutants of Escherichia coli aspartate aminotransferase. Protein Eng., 13, 2000
5EFS	The crystal structure of human kynurenine aminotransferase II 分子名称: Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial 著者 Nematollahi, A, Sun, G, Kwan, A, Harrop, S.J, Hanrahan, J.R, Nadvi, N.A, Church, W.B. 登録日 2015-10-26 公開日 2015-11-11 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (1.82503 Å) 主引用文献 The crystal structure of human kynurenine aminotransferase II To Be Published
6T8P	HKATII IN COMPLEX WITH LIGAND (2R)-N-benzyl-1-[6-methyl-5-(oxan-4-yl)-7-oxo-6H,7H-[1,3]thiazolo[5,4-d]pyrimidin-2-yl]pyrrolidine-2-carboxamide 分子名称: 1,2-ETHANEDIOL, 3,5-bis(fluoranyl)-~{N}-[5-[(2~{R})-2-(3-fluorophenyl)-3-methyl-butyl]-1,3,4-thiadiazol-2-yl]benzenesulfonamide, IODIDE ION, ... 著者 Blaesse, M, Venalainen, J. 登録日 2019-10-24 公開日 2020-03-04 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.02 Å) 主引用文献 Discovery of sulfonamides and 9-oxo-2,8-diazaspiro[5,5]undecane-2-carboxamides as human kynurenine aminotransferase 2 (KAT2) inhibitors. Bioorg.Med.Chem.Lett., 30, 2020
6T3V	Psychrophilic aromatic amino acids aminotransferase from Psychrobacter sp. B6 cocrystalized with substrate analog - malic acid 分子名称: (2S)-2-hydroxybutanedioic acid, Aminotransferase, PYRIDOXAL-5'-PHOSPHATE 著者 Rutkiewicz, M, Bujacz, A, Rum, J, Bujacz, G. 登録日 2019-10-11 公開日 2020-11-18 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.62 Å) 主引用文献 Structural Evidence of Active Site Adaptability towards Different Sized Substrates of Aromatic Amino Acid Aminotransferase from Psychrobacter Sp. B6. Materials, 14, 2021
6T8Q	HKATII IN COMPLEX WITH LIGAND (2R)-N-benzyl-1-[6-methyl-5-(oxan-4-yl)-7-oxo-6H,7H-[1,3]thiazolo[5,4-d]pyrimidin-2-yl]pyrrolidine-2-carboxamide 分子名称: (2~{R})-1-[6-methyl-5-(oxan-4-yl)-7-oxidanylidene-[1,3]thiazolo[5,4-d]pyrimidin-2-yl]-~{N}-(phenylmethyl)pyrrolidine-2-carboxamide, ACETATE ION, CADMIUM ION, ... 著者 Blaesse, M, Venalainen, J. 登録日 2019-10-24 公開日 2020-03-04 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.51 Å) 主引用文献 Discovery of sulfonamides and 9-oxo-2,8-diazaspiro[5,5]undecane-2-carboxamides as human kynurenine aminotransferase 2 (KAT2) inhibitors. Bioorg.Med.Chem.Lett., 30, 2020
5EUN	The Crystal Structure of Human Kynurenine Aminotransferase II, PLP-bound form, at 1.83 A 分子名称: Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial 著者 Nematollahi, A, Sun, G, Kwan, A, Jeffries, C.M, Harrop, S.J, Hanrahan, J.R, Nadvi, N.A, Church, W.B. 登録日 2015-11-18 公開日 2015-12-16 最終更新日 2016-08-10 実験手法 X-RAY DIFFRACTION (1.825 Å) 主引用文献 Structure of the PLP-Form of the Human Kynurenine Aminotransferase II in a Novel Spacegroup at 1.83 angstrom Resolution. Int J Mol Sci, 17, 2016
4M2J	Crystal structure of PLP-dependent cyclase OrfR in complex with Au 分子名称: Aminotransferase, GOLD ION, PYRIDOXAL-5'-PHOSPHATE 著者 Chang, C.Y, Liu, Y.C, Lyu, S.Y, Wu, C.C, Li, T.L. 登録日 2013-08-05 公開日 2014-06-18 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (2.95 Å) 主引用文献 Biosynthesis of streptolidine involved two unexpected intermediates produced by a dihydroxylase and a cyclase through unusual mechanisms. Angew.Chem.Int.Ed.Engl., 53, 2014

 

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