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1MPU
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Crystal Structure of the free human NKG2D immunoreceptor
分子名称: NKG2-D type II integral membrane protein, PHOSPHATE ION
著者McFarland, B.J, Kortemme, T, Baker, D, Strong, R.K.
登録日2002-09-12
公開日2003-04-15
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Symmetry Recognizing Asymmetry: Analysis of the Interactions between the C-Type Lectin-like Immunoreceptor NKG2D and MHC Class I-like Ligands
Structure, 11, 2003
7ODU
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Natural killer cell receptor NKR-P1B from Rattus norvegicus in complex with its cognate ligand Clr-11
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, C-type lectin domain family 2 member D11, ...
著者Skalova, T, Blaha, J, Kalouskova, B, Skorepa, O, Vanek, O, Dohnalek, J.
登録日2021-04-30
公開日2022-06-01
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Natural killer cell receptor NKR-P1B from Rattus norvegicus in complex with its cognate ligand Clr-11
To Be Published
5J2S
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NKR-P1B from Rattus norvegicus
分子名称: Killer cell lectin-like receptor subfamily B member 1B allele A, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose
著者Skalova, T, Vanek, O, Blaha, J, Duskova, J, Hasek, J, Koval, T, Dohnalek, J.
登録日2016-03-30
公開日2017-10-11
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structure of NKR-P1B from Rattus norvegicus
To Be Published
1FIH
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N-ACETYLGALACTOSAMINE BINDING MUTANT OF MANNOSE-BINDING PROTEIN A (QPDWG-HDRPY), COMPLEX WITH N-ACETYLGALACTOSAMINE
分子名称: 2-acetamido-2-deoxy-beta-D-galactopyranose, CALCIUM ION, CHLORIDE ION, ...
著者Feinberg, H, Torgerson, D, Drickamer, K, Weis, W.I.
登録日2000-08-03
公開日2000-08-23
最終更新日2021-11-03
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Mechanism of pH-dependent N-acetylgalactosamine binding by a functional mimic of the hepatocyte asialoglycoprotein receptor.
J.Biol.Chem., 275, 2000
7YTQ
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Human langerin carbohydrate recognition domain in complex with an alpha-mannoside ligand
分子名称: CALCIUM ION, CD207 molecule, CHLORIDE ION, ...
著者Wangkanont, K.
登録日2022-08-16
公開日2022-09-07
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Human langerin carbohydrate recognition domain in complex with an alpha-mannoside ligand
To Be Published
6W12
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Crystal Structure of the Carbohydrate Recognition Domain of the Human Macrophage Galactose C-Type Lectin Bound to the Tumor-Associated Tn Antigen
分子名称: 2-acetamido-2-deoxy-alpha-D-galactopyranose, C-type lectin domain family 10 member A, CALCIUM ION, ...
著者Birrane, G, Murphy, P.V, Gabba, A, Luz, J.G.
登録日2020-03-03
公開日2021-03-10
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal Structure of the Carbohydrate Recognition Domain of the Human Macrophage Galactose C-Type Lectin Bound to GalNAc and the Tumor-Associated Tn Antigen.
Biochemistry, 60, 2021
4UWW
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Crystallographic Structure of the Intramineral Protein Struthicalcin from Struthio camelus Eggshell
分子名称: STRUTHIOCALCIN-1
著者Ruiz, R.R, Moreno, A, Romero, A.
登録日2014-08-14
公開日2015-04-08
最終更新日2015-04-22
実験手法X-RAY DIFFRACTION (1.44 Å)
主引用文献Crystal Structure of Struthiocalcin-1, an Intramineral Protein from Struthio Camelus Eggshell, in Two Different Crystal Forms.
Acta Crystallogr.,Sect.D, 71, 2015
8A59
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C-type lectin-like domain (CTLD) and Sushi-like domain of human CD93
分子名称: Complement component C1q receptor, GLYCEROL, SULFATE ION
著者Tassone, G, Barbera, S, Raucci, L, Orlandini, M, Pozzi, C.
登録日2022-06-14
公開日2022-11-02
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (1.92 Å)
主引用文献Dimerization of the C-type lectin-like receptor CD93 promotes its binding to Multimerin-2 in endothelial cells.
Int.J.Biol.Macromol., 224, 2023
6LFJ
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Crystal structure of mouse DCAR2 CRD domain complex with IPM2
分子名称: 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, C-type lectin domain family 4, member b1, ...
著者Omahdi, Z, Horikawa, Y, Toyonaga, K, Kakuta, Y, Yamasaki, S.
登録日2019-12-03
公開日2020-03-25
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.84 Å)
主引用文献Structural insight into the recognition of pathogen-derived phosphoglycolipids by C-type lectin receptor DCAR.
J.Biol.Chem., 295, 2020
3KQG
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Trimeric Structure of Langerin
分子名称: C-type lectin domain family 4 member K, CALCIUM ION
著者Feinberg, H, Powlesland, A.S, Taylor, M.E, Weis, W.I.
登録日2009-11-17
公開日2010-02-23
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Trimeric structure of langerin.
J.Biol.Chem., 285, 2010
3KMB
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COMPLEX OF 3'-SULFO-LEWIS-X WITH A SELECTIN-LIKE MUTANT OF MANNOSE-BINDING PROTEIN A
分子名称: CALCIUM ION, CHLORIDE ION, MANNOSE-BINDING PROTEIN-A, ...
著者Ng, K.K.-S, Weis, W.I.
登録日1996-11-07
公開日1997-02-12
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Structure of a selectin-like mutant of mannose-binding protein complexed with sialylated and sulfated Lewis(x) oligosaccharides.
Biochemistry, 36, 1997
8W9J
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Crystal structure of human CLEC12A ectodomain complexed with 50C1 Fab
分子名称: Anti-human CLEC12A antibody 50C1 heavy chain, Anti-human CLEC12A antibody 50C1 light chain, C-type lectin domain family 12 member A
著者Mori, S, Nagae, M, Yamasaki, S.
登録日2023-09-05
公開日2024-03-06
最終更新日2024-05-15
実験手法X-RAY DIFFRACTION (3.5 Å)
主引用文献Crystal structure of the complex of CLEC12A and an antibody that interferes with binding of diverse ligands.
Int.Immunol., 36, 2024
8W8T
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Crystal structure of human CLEC12A CRD
分子名称: C-type lectin domain family 12 member A, SULFATE ION
著者Mori, S, Nagae, M, Yamasaki, S.
登録日2023-09-04
公開日2024-03-06
最終更新日2024-05-15
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal structure of the complex of CLEC12A and an antibody that interferes with binding of diverse ligands.
Int.Immunol., 36, 2024
5G6U
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Crystal structure of langerin carbohydrate recognition domain with GlcNS6S
分子名称: 2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose, CALCIUM ION, CHLORIDE ION, ...
著者Porkolab, V, Chabrol, E, Varga, N, Ordanini, S, Sutkeviciute, I, Thepaut, M, Bernardi, A, Fieschi, F.
登録日2016-07-21
公開日2018-02-21
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.844 Å)
主引用文献Rational-Differential Design of Highly Specific Glycomimetic Ligands: Targeting DC-SIGN and Excluding Langerin Recognition.
ACS Chem. Biol., 13, 2018
6LKR
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Crystal structure of mouse DCAR2 CRD domain complex
分子名称: 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, C-type lectin domain family 4, member b1, ...
著者Omahdi, Z, Horikawa, Y, Toyonaga, K, Kakuta, Y, Yamasaki, S.
登録日2019-12-20
公開日2020-03-25
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.84 Å)
主引用文献Structural insight into the recognition of pathogen-derived phosphoglycolipids by C-type lectin receptor DCAR.
J.Biol.Chem., 295, 2020
7NL7
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Crystal Structure of DC-SIGN in complex with a triazole-based glycomimetic ligand
分子名称: 3-Aminopropyl 2-deoxy-2-(4-phenyl-1,2,3-triazol-1-yl)-alpha-D-mannopyranoside, CALCIUM ION, DC-SIGN, ...
著者Jakob, R.P, Cramer, J, Lakkaichi, A, Aliu, B, Cattaneo, I, Klein, S, Jiang, X, Rabbani, S, Schwardt, O, Ernst, B, Maier, T.
登録日2021-02-22
公開日2021-10-27
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Sweet Drugs for Bad Bugs: A Glycomimetic Strategy against the DC-SIGN-Mediated Dissemination of SARS-CoV-2.
J.Am.Chem.Soc., 143, 2021
7NL6
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Crystal Structure of DC-SIGN in complex with a triazole-based glycomimetic ligand
分子名称: CALCIUM ION, DC-SIGN, CRD domain, ...
著者Jakob, R.P, Cramer, J, Lakkaichi, A, Aliu, B, Cattaneo, I, Klein, S, Jiang, X, Rabbani, S, Schwardt, O, Ernst, B, Maier, T.
登録日2021-02-22
公開日2021-10-27
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Sweet Drugs for Bad Bugs: A Glycomimetic Strategy against the DC-SIGN-Mediated Dissemination of SARS-CoV-2.
J.Am.Chem.Soc., 143, 2021
5FFT
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Crystal Structure of Surfactant Protein-A Y221A Mutant
分子名称: CALCIUM ION, Pulmonary surfactant-associated protein A
著者Goh, B.C, Wu, H, Rynkiewicz, M.J, Schulten, K, Seaton, B.A, McCormack, F.X.
登録日2015-12-18
公開日2016-07-06
最終更新日2019-12-11
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Elucidation of Lipid Binding Sites on Lung Surfactant Protein A Using X-ray Crystallography, Mutagenesis, and Molecular Dynamics Simulations.
Biochemistry, 55, 2016
5FFR
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Crystal Structure of Surfactant Protein-A complexed with phosphocholine
分子名称: CALCIUM ION, PHOSPHOCHOLINE, Pulmonary surfactant-associated protein A, ...
著者Goh, B.C, Wu, H, Rynkiewicz, M.J, Schulten, K, Seaton, B.A, McCormack, F.X.
登録日2015-12-18
公開日2016-07-06
最終更新日2019-12-11
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Elucidation of Lipid Binding Sites on Lung Surfactant Protein A Using X-ray Crystallography, Mutagenesis, and Molecular Dynamics Simulations.
Biochemistry, 55, 2016
5FFS
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Crystal Structure of Surfactant Protein-A Y164A Mutant
分子名称: CALCIUM ION, Pulmonary surfactant-associated protein A
著者Goh, B.C, Wu, H, Rynkiewicz, M.J, Schulten, K, Seaton, B.A, McCormack, F.X.
登録日2015-12-18
公開日2016-07-06
最終更新日2019-12-11
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Elucidation of Lipid Binding Sites on Lung Surfactant Protein A Using X-ray Crystallography, Mutagenesis, and Molecular Dynamics Simulations.
Biochemistry, 55, 2016
8JAH
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Crystal structure of human CLEC12A C-type lectin domain
分子名称: C-type lectin domain family 12 member A, POTASSIUM ION, SULFATE ION
著者Lei, Q, Tang, H, Dong, X.
登録日2023-05-06
公開日2024-03-13
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.58 Å)
主引用文献Mechanistic insights into the C-type lectin receptor CLEC12A-mediated immune recognition of monosodium urate crystal.
J.Biol.Chem., 300, 2024
7QAJ
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ZK002 with Anti-angiogenic and Anti-inflamamtory Properties
分子名称: SULFATE ION, Snaclec clone 2100755 alpha, Snaclec clone 2100755 beta
著者Wong, W.Y, Chan, B.D, Muk Lan Lee, M, Dai, X, Tsim, K.W.K, Hsiao, W.L.W, Li, M, Li, X.Y, Tai, W.C.S.
登録日2021-11-17
公開日2023-06-14
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Isolation and characterization of ZK002, a novel dual function snake venom protein from Deinagkistrodon acutus with anti-angiogenic and anti-inflammatory properties.
Front Pharmacol, 14, 2023
7R8U
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LOX-1 - Structural and Functional Studies of a Receptor Implicated in Atherosclerosis
分子名称: Antibody light chain, kappa, Antigen binding fragment, ...
著者Oganesyan, V, van Dyk, N.
登録日2021-06-27
公開日2022-06-01
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.901 Å)
主引用文献Structural and functional studies of a monoclonal antibody blocking LOX-1
Commun Med, 2023
8OUQ
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Clr-11 from Rattus norvegicus
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, C-type lectin domain family 2 member D11
著者Skalova, T, Blaha, J, Kalouskova, B, Skorepa, O, Vanek, O, Dohnalek, J.
登録日2023-04-24
公開日2024-05-01
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Clr-11 from Rattus norvegicus
To Be Published
5VYB
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Structure of the carbohydrate recognition domain of Dectin-2 complexed with a mammalian-type high mannose Man9GlcNAc2 oligosaccharide
分子名称: C-type lectin domain family 6 member A, CALCIUM ION, DI(HYDROXYETHYL)ETHER, ...
著者Feinberg, H, Jegouzo, S.A.F, Rex, M.J, Drickamer, K, Taylor, M.E, Weis, W.I.
登録日2017-05-24
公開日2017-07-05
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Mechanism of pathogen recognition by human dectin-2.
J. Biol. Chem., 292, 2017

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