6TL9

CRYSTAL STRUCTURE OF LECTIN-LIKE OX-LDL RECEPTOR 1 IN COMPLEX WITH BI-0115

Summary for 6TL9

Entry DOI	10.2210/pdb6tl9/pdb
Descriptor	Oxidized low-density lipoprotein receptor 1, GLYCEROL, 9-chloranyl-5-propyl-11~{H}-pyrido[2,3-b][1,4]benzodiazepin-6-one, ... (4 entities in total)
Functional Keywords	lox-1, olr1, ctld, c-type lectin like domain, scavenger receptor, oxldl binding, ppi stabilization, inhibitor, lipid binding protein
Biological source	Homo sapiens (Human)
Total number of polymer chains	8
Total formula weight	124278.68
Authors	Nar, H.,Fiegen, D.,Schnapp, G. (deposition date: 2019-12-02, release date: 2020-07-22, Last modification date: 2024-10-16)
Primary citation	Nar, H.,Fiegen, D.,Schnapp, G. A small-molecule inhibitor of lectin-like oxidized LDL receptor-1 acts by stabilizing an inactive receptor tetramer state Commun Chem, 2020 Cited by DOI: 10.1038/s42004-020-0321-2 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.734 Å)

Structure validation