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6TL9

CRYSTAL STRUCTURE OF LECTIN-LIKE OX-LDL RECEPTOR 1 IN COMPLEX WITH BI-0115

Summary for 6TL9
Entry DOI10.2210/pdb6tl9/pdb
DescriptorOxidized low-density lipoprotein receptor 1, GLYCEROL, 9-chloranyl-5-propyl-11~{H}-pyrido[2,3-b][1,4]benzodiazepin-6-one, ... (4 entities in total)
Functional Keywordslox-1, olr1, ctld, c-type lectin like domain, scavenger receptor, oxldl binding, ppi stabilization, inhibitor, lipid binding protein
Biological sourceHomo sapiens (Human)
Total number of polymer chains8
Total formula weight124278.68
Authors
Nar, H.,Fiegen, D.,Schnapp, G. (deposition date: 2019-12-02, release date: 2020-07-22, Last modification date: 2024-10-16)
Primary citationNar, H.,Fiegen, D.,Schnapp, G.
A small-molecule inhibitor of lectin-like oxidized LDL receptor-1 acts by stabilizing an inactive receptor tetramer state
Commun Chem, 2020
Cited by
DOI: 10.1038/s42004-020-0321-2
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.734 Å)
Structure validation

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