1M3V
 
 | | FLIN4: Fusion of the LIM binding domain of Ldb1 and the N-terminal LIM domain of LMO4 | | 分子名称: | ZINC ION, fusion of the LIM interacting domain of ldb1 and the N-terminal LIM domain of LMO4 | | 著者 | Deane, J.E, Mackay, J.P, Kwan, A.H.Y, Sum, E.Y, Visvader, J.E, Matthews, J.M. | | 登録日 | 2002-06-30 | | 公開日 | 2003-05-13 | | 最終更新日 | 2024-05-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structural basis for the recognition of ldb1 by the N-terminal LIM domains of LMO2 and LMO4
EMBO J., 22, 2003
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1RUT
 | | Complex of LMO4 LIM domains 1 and 2 with the ldb1 LID domain | | 分子名称: | Fusion protein of Lmo4 protein and LIM domain-binding protein 1, ZINC ION | | 著者 | Deane, J.E, Ryan, D.P, Maher, M.J, Kwan, A.H.Y, Bacca, M, Mackay, J.P, Guss, J.M, Visvader, J.E, Matthews, J.M. | | 登録日 | 2003-12-11 | | 公開日 | 2004-10-12 | | 最終更新日 | 2024-05-29 | | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | | 主引用文献 | Tandem LIM domains provide synergistic binding in the LMO4:Ldb1 complex
Embo J., 23, 2004
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1J2O
 | | Structure of FLIN2, a complex containing the N-terminal LIM domain of LMO2 and ldb1-LID | | 分子名称: | Fusion of Rhombotin-2 and LIM domain-binding protein 1, ZINC ION | | 著者 | Deane, J.E, Mackay, J.P, Kwan, A.H, Sum, E.Y, Visvader, J.E, Matthews, J.M. | | 登録日 | 2003-01-08 | | 公開日 | 2003-05-13 | | 最終更新日 | 2023-12-27 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structural basis for the recognition of ldb1 by the N-terminal LIM domains of LMO2 and LMO4
EMBO J., 22, 2003
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6TYD
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2LXD
 | | Backbone 1H, 13C, and 15N Chemical Shift Assignments for LMO2(LIM2)-Ldb1(LID) | | 分子名称: | Rhombotin-2,LIM domain-binding protein 1, ZINC ION | | 著者 | Dastmalchi, S, Wilkinson-White, L, Kwan, A.H, Gamsjaeger, R, Mackay, J.P, Matthews, J.M. | | 登録日 | 2012-08-20 | | 公開日 | 2012-09-12 | | 最終更新日 | 2024-05-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structure of a tethered Lmo2(LIM2) /Ldb1(LID) complex.
Protein Sci., 21, 2012
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6PTL
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8HIB
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7OB5
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7OB8
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2JTN
 | | NMR Solution Structure of a ldb1-LID:Lhx3-LIM complex | | 分子名称: | LIM domain-binding protein 1, LIM/homeobox protein Lhx3, ZINC ION | | 著者 | Lee, C, Nancarrow, A.L, Mackay, J.P, Matthews, J.M. | | 登録日 | 2007-08-03 | | 公開日 | 2008-06-17 | | 最終更新日 | 2024-05-29 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Implementing the LIM code: the structural basis for cell type-specific assembly of LIM-homeodomain complexes
Embo J., 27, 2008
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2XJZ
 | | Crystal structure of the LMO2:LDB1-LID complex, C2 crystal form | | 分子名称: | CHLORIDE ION, LIM DOMAIN-BINDING PROTEIN 1, RHOMBOTIN-2, ... | | 著者 | El Omari, K, Karia, D, Porcher, C, Mancini, E.J. | | 登録日 | 2010-07-06 | | 公開日 | 2010-07-21 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Structure of the Leukemia Oncogene Lmo2: Implications for the Assembly of a Hematopoietic Transcription Factor Complex.
Blood, 117, 2011
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2XJY
 | | Crystal structure of the LMO2:LDB1-LID complex, P21 crystal form | | 分子名称: | LIM DOMAIN-BINDING PROTEIN 1, RHOMBOTIN-2, ZINC ION | | 著者 | El Omari, K, Karia, D, Porcher, C, Mancini, E.J. | | 登録日 | 2010-07-06 | | 公開日 | 2010-07-21 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Structure of the Leukemia Oncogene Lmo2: Implications for the Assembly of a Hematopoietic Transcription Factor Complex.
Blood, 117, 2011
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2YPA
 | | Structure of the SCL:E47:LMO2:LDB1 complex bound to DNA | | 分子名称: | EBOX FORWARD, EBOX REVERSE, LIM DOMAIN-BINDING PROTEIN 1, ... | | 著者 | El Omari, K, Hoosdally, S.J, Tuladhar, K, Karia, D, Ponsele, E, Platonova, O, Vyas, P, Patient, R, Porcher, C, Mancini, E.J. | | 登録日 | 2012-10-30 | | 公開日 | 2013-07-31 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Structural Basis for Lmo2-Driven Recruitment of the Scl:E47bHLH Heterodimer to Hematopoietic-Specific Transcriptional Targets.
Cell Rep., 4, 2013
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4JCJ
 | | Crystal structure of Isl1 LIM domains with Ldb1 LIM-interaction domain | | 分子名称: | Insulin gene enhancer protein ISL-1,LIM domain-binding protein 1, ZINC ION | | 著者 | Gadd, M.S, Jacques, D.A, Guss, J.M, Matthews, J.M. | | 登録日 | 2013-02-21 | | 公開日 | 2013-06-19 | | 最終更新日 | 2017-11-15 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | A structural basis for the regulation of the LIM-homeodomain protein islet 1 (Isl1) by intra- and intermolecular interactions.
J.Biol.Chem., 288, 2013
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6S9T
 | | Dimerization domain of Xenopus laevis LDB1 in complex with darpin 3 | | 分子名称: | Darpin 3, LIM domain-binding protein 1, TETRAETHYLENE GLYCOL | | 著者 | Renko, M, Schaefer, J.V, Pluckthun, A, Bienz, M. | | 登録日 | 2019-07-15 | | 公開日 | 2019-10-09 | | 最終更新日 | 2019-10-23 | | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | | 主引用文献 | Rotational symmetry of the structured Chip/LDB-SSDP core module of the Wnt enhanceosome.
Proc.Natl.Acad.Sci.USA, 116, 2019
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6S9S
 | | Dimerization domain of Xenopus laevis LDB1 in complex with darpin 10 | | 分子名称: | Darpin 10, LIM domain-binding protein 1 | | 著者 | Renko, M, Schaefer, J.V, Pluckthun, A, Bienz, M. | | 登録日 | 2019-07-15 | | 公開日 | 2019-10-09 | | 最終更新日 | 2019-10-23 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Rotational symmetry of the structured Chip/LDB-SSDP core module of the Wnt enhanceosome.
Proc.Natl.Acad.Sci.USA, 116, 2019
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2DFY
 | | Crystal structure of a cyclized protein fusion of LMO4 LIM domains 1 and 2 with the LIM interacting domain of LDB1 | | 分子名称: | GLYCEROL, ZINC ION, fusion protein of LIM domain transcription factor LMO4 and LIM domain-binding protein 1 | | 著者 | Jeffries, C.M.J, Graham, S.C, Collyer, C.A, Guss, J.M, Matthews, J.M. | | 登録日 | 2006-03-06 | | 公開日 | 2006-10-31 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | | 主引用文献 | Stabilization of a binary protein complex by intein-mediated cyclization
Protein Sci., 15, 2006
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2L6Z
 | | haddock model of GATA1NF:Lmo2LIM2-Ldb1LID with FOG | | 分子名称: | Erythroid transcription factor, LIM domain only 2, linker, ... | | 著者 | Wilkinson-White, L, Gamsjaeger, R, Dastmalchi, S, Wienert, B, Stokes, P.H, Crossley, M, Mackay, J.P, Matthews, J.M. | | 登録日 | 2010-12-01 | | 公開日 | 2011-08-31 | | 最終更新日 | 2024-05-01 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structural basis of simultaneous recruitment of the transcriptional regulators LMO2 and FOG1/ZFPM1 by the transcription factor GATA1
Proc.Natl.Acad.Sci.USA, 108, 2011
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2L6Y
 | | haddock model of GATA1NF:Lmo2LIM2-Ldb1LID | | 分子名称: | Erythroid transcription factor, LIM domain only 2, linker, ... | | 著者 | Wilkinson-White, L, Gamsjaeger, R, Dastmalchi, S, Wienert, B, Stokes, P.H, Crossley, M, Mackay, J.P, Matthews, J.M. | | 登録日 | 2010-12-01 | | 公開日 | 2011-08-31 | | 最終更新日 | 2024-05-01 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structural basis of simultaneous recruitment of the transcriptional regulators LMO2 and FOG1/ZFPM1 by the transcription factor GATA1
Proc.Natl.Acad.Sci.USA, 108, 2011
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8SSU
 | | ZnFs 3-11 of CCCTC-binding factor (CTCF) Complexed with 19mer DNA | | 分子名称: | 1,2-ETHANEDIOL, DNA (19-MER) Strand I, DNA (19-MER) Strand II, ... | | 著者 | Horton, J.R, Yang, J, Cheng, X. | | 登録日 | 2023-05-08 | | 公開日 | 2023-08-02 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.89 Å) | | 主引用文献 | Structures of CTCF-DNA complexes including all 11 zinc fingers.
Nucleic Acids Res., 51, 2023
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2YPB
 | | Structure of the SCL:E47 complex bound to DNA | | 分子名称: | EBOX FORWARD, EBOX REVERSE, T-CELL ACUTE LYMPHOCYTIC LEUKEMIA PROTEIN 1, ... | | 著者 | El Omari, K, Hoosdally, S.J, Tuladhar, K, Karia, D, Ponsele, E, Platonova, O, Vyas, P, Patient, R, Porcher, C, Mancini, E.J. | | 登録日 | 2012-10-30 | | 公開日 | 2013-07-31 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2.87 Å) | | 主引用文献 | Structural Basis for Lmo2-Driven Recruitment of the Scl:E47bHLH Heterodimer to Hematopoietic-Specific Transcriptional Targets.
Cell Rep., 4, 2013
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2RGT
 | | Crystal Structure of Lhx3 LIM domains 1 and 2 with the binding domain of Isl1 | | 分子名称: | Fusion of LIM/homeobox protein Lhx3, linker, Insulin gene enhancer protein ISL-1, ... | | 著者 | Bhati, M, Lee, M, Guss, J.M, Matthews, J.M. | | 登録日 | 2007-10-05 | | 公開日 | 2008-08-12 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | | 主引用文献 | Implementing the LIM code: the structural basis for cell type-specific assembly of LIM-homeodomain complexes.
Embo J., 27, 2008
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6CME
 | | Structure of wild-type ISL2-LID in complex with LHX4-LIM1+2 | | 分子名称: | LIM/homeobox protein Lhx4,Insulin gene enhancer protein ISL-2, ZINC ION | | 著者 | Stokes, P.H, Silva, A, Guss, J.M, Matthews, J.M. | | 登録日 | 2018-03-04 | | 公開日 | 2019-04-10 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (1.92 Å) | | 主引用文献 | Mutation in a flexible linker modulates binding affinity for modular complexes.
Proteins, 87, 2019
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3VD6
 | | Both Zn Fingers of GATA1 Bound to Palindromic DNA Recognition Site, P21 Crystal Form | | 分子名称: | ACETATE ION, DNA (5'-D(*AP*AP*GP*AP*GP*TP*CP*CP*AP*TP*CP*TP*GP*AP*TP*AP*AP*GP*AP*C)-3'), DNA (5'-D(*TP*TP*GP*TP*CP*TP*TP*AP*TP*CP*AP*GP*AP*TP*GP*GP*AP*CP*TP*C)-3'), ... | | 著者 | Jacques, D.A, Ripin, N, Wilkinson-White, L.E, Guss, J.M, Matthews, J.M. | | 登録日 | 2012-01-04 | | 公開日 | 2013-01-16 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.98 Å) | | 主引用文献 | GATA1 directly mediates interactions with closely spaced pseudopalindromic but not distantly spaced double GATA sites on DNA.
Protein Sci., 24, 2015
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3VEK
 | | Both Zn Fingers of GATA1 Bound to Palindromic DNA Recognition Site, P1 Crystal Form | | 分子名称: | DNA (5'-D(*AP*AP*GP*AP*GP*TP*CP*CP*AP*TP*CP*TP*GP*AP*TP*AP*AP*GP*AP*C)-3'), DNA (5'-D(*TP*TP*GP*TP*CP*TP*TP*AP*TP*CP*AP*GP*AP*TP*GP*GP*AP*CP*TP*C)-3'), Erythroid transcription factor, ... | | 著者 | Jacques, D.A, Ripin, N, Wilkinson-White, L.E, Guss, J.M, Matthews, J.M. | | 登録日 | 2012-01-09 | | 公開日 | 2013-01-16 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.63 Å) | | 主引用文献 | GATA1 directly mediates interactions with closely spaced pseudopalindromic but not distantly spaced double GATA sites on DNA.
Protein Sci., 24, 2015
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