6CME
Structure of wild-type ISL2-LID in complex with LHX4-LIM1+2
Summary for 6CME
Entry DOI | 10.2210/pdb6cme/pdb |
Related | 2JTN 2rgt 3mmk |
Descriptor | LIM/homeobox protein Lhx4,Insulin gene enhancer protein ISL-2, ZINC ION (3 entities in total) |
Functional Keywords | lim-homeodomain, cell-type specification, neural development, transcription |
Biological source | Mus musculus (Mouse) More |
Total number of polymer chains | 2 |
Total formula weight | 38022.08 |
Authors | Stokes, P.H.,Silva, A.,Guss, J.M.,Matthews, J.M. (deposition date: 2018-03-04, release date: 2019-04-10, Last modification date: 2023-10-04) |
Primary citation | Stokes, P.H.,Robertson, N.O.,Silva, A.P.G.,Estephan, T.,Trewhella, J.,Guss, J.M.,Matthews, J.M. Mutation in a flexible linker modulates binding affinity for modular complexes. Proteins, 87:425-429, 2019 Cited by PubMed: 30788856DOI: 10.1002/prot.25675 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.92 Å) |
Structure validation
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