6CME

Structure of wild-type ISL2-LID in complex with LHX4-LIM1+2

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	LIM/homeobox protein Lhx4,Insulin gene enhancer protein ISL-2	polymer	169	18749.4	2	UniProt (P53776) UniProt (Q9CXV0) Pfam (PF00412)	Mus musculus (Mouse)	LIM homeobox protein 4,Islet-2
2	C, D, E, F, G... (A, B)	ZINC ION	non-polymer		65.4	8	Chemie (ZN)
3	K, L (A, B)	water	water		18.0	210	Chemie (HOH)

Sequence modifications

A, B: 24 - 260 (UniProt: P53776)

PDB	External Database	Details
Gly 22	-	expression tag
Ser 23	-	expression tag
Gly 261	-	linker
Gly 262	-	linker
Ser 263	-	linker
Gly 264	-	linker
Gly 265	-	linker
His 266	-	linker
Met 267	-	linker
Gly 268	-	linker
Ser 269	-	linker
Gly 270	-	linker
Gly 271	-	linker

A, B: 272 - 301 (UniProt: Q9CXV0)

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	37498.8
Non-Polymers*	Number of molecules	8
	Total formula weight	523.3
All*	Total formula weight	38022.1

*Water molecules are not included.