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6ZR1
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BU of 6zr1 by Molmil
Racemic compound of RNA duplexes.
分子名称: RNA (5'-R(*(0C)P*(0C)P*(0G)P*(0C)P*(0C)P*(0U)P*(0G)P*(0G))-3'), RNA (5'-R(*(0C)P*(0U)P*(0G)P*(0G)P*(0G)P*(0C)P*(0G)P*(0G))-3'), RNA (5'-R(*CP*CP*GP*CP*CP*UP*GP*G)-3'), ...
著者Rypniewski, W.
登録日2020-07-10
公開日2021-05-26
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.528 Å)
主引用文献Broken symmetry between RNA enantiomers in a crystal lattice.
Nucleic Acids Res., 49, 2021
6M9M
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BU of 6m9m by Molmil
Streptococcus mutans AlkD2 bound to inosine-5'-monophosphate
分子名称: AlkD2, CHLORIDE ION, INOSINIC ACID
著者Eichman, B.F, Shi, R.
登録日2018-08-23
公開日2018-10-10
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.401 Å)
主引用文献Structural Biology of the HEAT-Like Repeat Family of DNA Glycosylases.
Bioessays, 40, 2018
7M76
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BU of 7m76 by Molmil
Room Temperature XFEL Crystallography reveals asymmetry in the vicinity of the two phylloquinones in Photosystem I
分子名称: 1,2-DIPALMITOYL-PHOSPHATIDYL-GLYCEROLE, 1,2-DISTEAROYL-MONOGALACTOSYL-DIGLYCERIDE, BETA-CAROTENE, ...
著者Keable, S.M, Simon, P.S, Kolsch, A, Kern, J, Yachandra, V.K, Zouni, A, Yano, J.
登録日2021-03-26
公開日2021-11-24
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Room temperature XFEL crystallography reveals asymmetry in the vicinity of the two phylloquinones in photosystem I.
Sci Rep, 11, 2021
6ZX5
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BU of 6zx5 by Molmil
Racemic compound of RNA duplexes.
分子名称: RNA (5'-R(*(0C)P*(0C)P*(0G)P*(0C)P*(0C)P*(0U)P*(0G)P*(0G))-3'), RNA (5'-R(*(0C)P*(0U)P*(0G)P*(0G)P*(0G)P*(0C)P*(0G)P*(0G))-3'), RNA (5'-R(*CP*CP*GP*CP*CP*UP*GP*G)-3'), ...
著者Rypniewski, W.
登録日2020-07-29
公開日2021-05-26
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.523 Å)
主引用文献Broken symmetry between RNA enantiomers in a crystal lattice.
Nucleic Acids Res., 49, 2021
6PCO
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BU of 6pco by Molmil
Mechanism for regulation of DNA binding of Bordetella bronchiseptica BpsR by 6-hydroxynicotinic acid
分子名称: 1,4-BUTANEDIOL, MarR-family transcriptional regulator
著者Booth, W.T, Davis, R.R, Deora, R, Hollis, T.
登録日2019-06-17
公開日2019-11-06
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.75 Å)
主引用文献Structural mechanism for regulation of DNA binding of BpsR, a Bordetella regulator of biofilm formation, by 6-hydroxynicotinic acid.
Plos One, 14, 2019
6MDM
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BU of 6mdm by Molmil
The 20S supercomplex engaging the SNAP-25 N-terminus (class 1)
分子名称: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Alpha-soluble NSF attachment protein, ...
著者White, K.I, Zhao, M, Brunger, A.T.
登録日2018-09-04
公開日2018-09-19
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (4.4 Å)
主引用文献Structural principles of SNARE complex recognition by the AAA+ protein NSF.
Elife, 7, 2018
6TXK
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BU of 6txk by Molmil
Crystal structure of thermotoga maritima E65K Ferritin
分子名称: EICOSANE, FE (III) ION, Ferritin, ...
著者Wilk, P, Grudnik, P, Kumar, M, Heddle, J, Chakraborti, S.
登録日2020-01-14
公開日2021-07-28
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.359 Å)
主引用文献A single residue can modulate nanocage assembly in salt dependent ferritin.
Nanoscale, 13, 2021
8DKK
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BU of 8dkk by Molmil
Polymorphism in SARS-CoV-2 Nsp5 main protease reveals differences in cleavage of viral and host substrates
分子名称: 3C-like proteinase nsp5
著者Lu, J, Khan, M.B, Young, H.S, Lemieux, M.J.
登録日2022-07-05
公開日2023-05-03
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献SARS-CoV-2 M pro Protease Variants of Concern Display Altered Viral Substrate and Cell Host Target Galectin-8 Processing but Retain Sensitivity toward Antivirals.
Acs Cent.Sci., 9, 2023
6MA4
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BU of 6ma4 by Molmil
Crystal structure of human O-GlcNAc transferase bound to a peptide from HCF-1 pro-repeat 2 (11-26) and inhibitor 3a
分子名称: 5-{2-[(1R)-2-{(carboxymethyl)[(thiophen-2-yl)methyl]amino}-2-oxo-1-{[(2-oxo-1,2-dihydroquinolin-6-yl)sulfonyl]amino}ethyl]phenoxy}pentanoic acid, Host Cell Factor 1 peptide, UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit
著者Martin, S.E.S, Lazarus, M.B, Walker, S.
登録日2018-08-25
公開日2018-10-17
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structure-Based Evolution of Low Nanomolar O-GlcNAc Transferase Inhibitors.
J. Am. Chem. Soc., 140, 2018
7A0N
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BU of 7a0n by Molmil
Structure of TSC1 NTD and linker domain
分子名称: Uncharacterized protein,Uncharacterized protein
著者Fitzian, K, Kuemmel, D.
登録日2020-08-10
公開日2021-05-26
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (4.3 Å)
主引用文献TSC1 binding to lysosomal PIPs is required for TSC complex translocation and mTORC1 regulation.
Mol.Cell, 81, 2021
7M3T
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BU of 7m3t by Molmil
Crystallographic structure of a cubic crystal of STMV (80.7 degree rotation about 111) grown from chloride
分子名称: CHLORIDE ION, Coat protein, MAGNESIUM ION, ...
著者McPherson, A.
登録日2021-03-19
公開日2021-12-15
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Structures of additional crystal forms of Satellite tobacco mosaic virus grown from a variety of salts.
Acta Crystallogr.,Sect.F, 77, 2021
6PCW
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BU of 6pcw by Molmil
Human PIM1 bound to benzothiophene inhibitor 213
分子名称: 4-[5-(cyclopropylcarbamoyl)thiophen-2-yl]-1-benzothiophene-2-carboxamide, GLYCEROL, Peptide, ...
著者Godoi, P.H.C, Santiago, A.S, Fala, A.M, Ramos, P.Z, Sriranganadane, D, Mascarello, A, Segretti, N, Azevedo, H, Guimaraes, C.R.W, Arruda, P, Elkins, J.M, Counago, R.M, Structural Genomics Consortium (SGC)
登録日2019-06-18
公開日2019-07-24
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献PIM1 bound to benzothiophene inhibitor
To Be Published
6TXI
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BU of 6txi by Molmil
Crystal structure of thermotoga maritima E65A Ferritin
分子名称: EICOSANE, FE (III) ION, Ferritin, ...
著者Wilk, P, Grudnik, P, Kumar, M, Heddle, J, Chakraborti, S.
登録日2020-01-14
公開日2021-07-28
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.759 Å)
主引用文献A single residue can modulate nanocage assembly in salt dependent ferritin.
Nanoscale, 13, 2021
8E5S
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BU of 8e5s by Molmil
X-ray structure of the Deinococcus radiodurans Nramp/MntH divalent transition metal transporter WT in an occluded state
分子名称: (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ...
著者Ray, S, Gaudet, R.
登録日2022-08-22
公開日2023-05-03
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.38 Å)
主引用文献High-resolution structures with bound Mn 2+ and Cd 2+ map the metal import pathway in an Nramp transporter.
Elife, 12, 2023
6MAQ
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BU of 6maq by Molmil
F9 Pilus Adhesin FmlH Lectin Domain from E. coli UTI89 in Complex with Galactoside 2'-{[(2S,3R,4R,5R,6R)-3-acetamido-4,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}-5-nitro-[1,1'-biphenyl]-3-carboxylic acid
分子名称: 2'-{[2-(acetylamino)-2-deoxy-beta-D-galactopyranosyl]oxy}-5-nitro[1,1'-biphenyl]-3-carboxylic acid, Fimbrial adhesin FmlD, GLYCEROL
著者Klein, R.D, Hultgren, S.J.
登録日2018-08-28
公開日2019-09-04
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.31 Å)
主引用文献Biphenyl Gal and GalNAc FmlH Lectin Antagonists of Uropathogenic E. coli (UPEC): Optimization through Iterative Rational Drug Design.
J.Med.Chem., 62, 2019
6PCZ
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BU of 6pcz by Molmil
Crystal structure of the bacterial cellulose synthase subunit G (BcsG) catalytic domain from Escherichia coli, selenomethionine variant
分子名称: Cellulose biosynthesis protein BcsG, MAGNESIUM ION, ZINC ION
著者Anderson, A.C, Brenner, T, Weadge, J.T.
登録日2019-06-18
公開日2020-03-18
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (1.44 Å)
主引用文献TheEscherichia colicellulose synthase subunit G (BcsG) is a Zn2+-dependent phosphoethanolamine transferase.
J.Biol.Chem., 295, 2020
6U46
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BU of 6u46 by Molmil
Solution Structure of a Heat-Resistant Long-Acting Insulin Analog
分子名称: Insulin
著者Yang, Y, Weiss, M.A.
登録日2019-08-23
公開日2020-08-26
最終更新日2024-10-23
実験手法SOLUTION NMR
主引用文献Solution Structure of a Heat-Resistant Long-Acting Insulin Analog
To Be Published
6ZRL
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BU of 6zrl by Molmil
Racemic compound of RNA duplexes.
分子名称: RNA (5'-R(*(0C)P*(0C)P*(0G)P*(0C)P*(0C)P*(0U)P*(0G)P*(0G))-3'), RNA (5'-R(*(0C)P*(0U)P*(0G)P*(0G)P*(0G)P*(0C)P*(0G)P*(0G))-3'), RNA (5'-R(*CP*CP*GP*CP*CP*UP*GP*G)-3'), ...
著者Rypniewski, W.
登録日2020-07-13
公開日2021-05-26
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.53 Å)
主引用文献Broken symmetry between RNA enantiomers in a crystal lattice.
Nucleic Acids Res., 49, 2021
7M54
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BU of 7m54 by Molmil
Crystallographic structure of a cubic crystal form of STMV grown from bromide
分子名称: BROMIDE ION, CALCIUM ION, CHLORIDE ION, ...
著者McPherson, A.
登録日2021-03-22
公開日2021-12-15
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (3.8 Å)
主引用文献Structures of additional crystal forms of Satellite tobacco mosaic virus grown from a variety of salts.
Acta Crystallogr.,Sect.F, 77, 2021
6MAY
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BU of 6may by Molmil
Crystal structure of N-myristoyl transferase (NMT) G386E mutant from Plasmodium vivax
分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, Glycylpeptide N-tetradecanoyltransferase, ...
著者Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2018-08-29
公開日2019-06-05
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Structure-Guided Identification of Resistance Breaking Antimalarial N‐Myristoyltransferase Inhibitors.
Cell Chem Biol, 26, 2019
6PPN
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BU of 6ppn by Molmil
Structure of S. pombe Lsm2-8 with unprocessed U6 snRNA
分子名称: Mimic of unprocessed U6 snRNA, Probable U6 snRNA-associated Sm-like protein LSm3, Probable U6 snRNA-associated Sm-like protein LSm4, ...
著者Montemayor, E.J, Butcher, S.E.
登録日2019-07-08
公開日2020-06-17
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.91 Å)
主引用文献Molecular basis for the distinct cellular functions of the Lsm1-7 and Lsm2-8 complexes.
Rna, 26, 2020
6ZY5
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BU of 6zy5 by Molmil
Cryo-EM structure of the Human topoisomerase II alpha DNA-binding/cleavage domain in State 1
分子名称: (5S,5aR,8aR,9R)-9-(4-hydroxy-3,5-dimethoxyphenyl)-8-oxo-5,5a,6,8,8a,9-hexahydrofuro[3',4':6,7]naphtho[2,3-d][1,3]dioxol -5-yl 4,6-O-[(1R)-ethylidene]-beta-D-glucopyranoside, DNA (5'-D(*CP*GP*CP*GP*CP*AP*TP*CP*GP*TP*CP*AP*TP*CP*CP*TP*C)-3'), DNA (5'-D(*GP*AP*GP*GP*AP*TP*GP*AP*CP*GP*AP*TP*G)-3'), ...
著者Vanden Broeck, A, Lamour, V.
登録日2020-07-30
公開日2021-05-26
最終更新日2024-05-01
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Structural basis for allosteric regulation of Human Topoisomerase II alpha.
Nat Commun, 12, 2021
6UCO
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BU of 6uco by Molmil
Backbone-modified variant of zinc finger 2 from the transcription factor Sp1 DNA binding domain: BTD in the metal-binding turn
分子名称: Transcription factor Sp1, ZINC ION
著者Rao, S.R, Horne, W.S.
登録日2019-09-17
公開日2020-06-24
最終更新日2024-10-16
実験手法SOLUTION NMR
主引用文献Proteomimetic Zinc Finger Domains with Modified Metal-binding beta-Turns.
Pept Sci (Hoboken), 112, 2020
8E7A
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BU of 8e7a by Molmil
Crystal structure of the p53 (Y107H) core domain orthorhombic P form
分子名称: Cellular tumor antigen p53, ZINC ION
著者Lovell, S, Liu, L, Battaile, K.P, Miller, S, Karanicolas, J.
登録日2022-08-23
公開日2023-05-17
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.3 Å)
主引用文献An African-Specific Variant of TP53 Reveals PADI4 as a Regulator of p53-Mediated Tumor Suppression.
Cancer Discov, 13, 2023
7M50
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BU of 7m50 by Molmil
Crystallographic structure of a cubic crystal form of STMV grown from ammonium sulfate
分子名称: CHLORIDE ION, Coat protein, MAGNESIUM ION, ...
著者McPherson, A.
登録日2021-03-22
公開日2021-12-15
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.31 Å)
主引用文献Structures of additional crystal forms of Satellite tobacco mosaic virus grown from a variety of salts.
Acta Crystallogr.,Sect.F, 77, 2021

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件を2024-10-30に公開中

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