6B8E
 
 | | Multiconformer model of apo WT PTP1B with glycerol at 180 K | | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, GLYCEROL, Tyrosine-protein phosphatase non-receptor type 1 | | 著者 | Keedy, D.A, Hill, Z.B, Biel, J.T, Kang, E, Rettenmaier, T.J, Brandao-Neto, J, von Delft, F, Wells, J.A, Fraser, J.S. | | 登録日 | 2017-10-06 | | 公開日 | 2018-06-20 | | 最終更新日 | 2024-05-22 | | 実験手法 | X-RAY DIFFRACTION (1.82 Å) | | 主引用文献 | An expanded allosteric network in PTP1B by multitemperature crystallography, fragment screening, and covalent tethering.
Elife, 7, 2018
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1F9I
 | | CRYSTAL STRUCTURE OF THE PHOTOACTIVE YELLOW PROTEIN MUTANT Y42F | | 分子名称: | 4'-HYDROXYCINNAMIC ACID, PHOTOACTIVE YELLOW PROTEIN | | 著者 | Brudler, R, Meyer, T.E, Genick, U.K, Tollin, G, Getzoff, E.D. | | 登録日 | 2000-07-10 | | 公開日 | 2000-07-21 | | 最終更新日 | 2021-11-03 | | 実験手法 | X-RAY DIFFRACTION (1.1 Å) | | 主引用文献 | Coupling of hydrogen bonding to chromophore conformation and function in photoactive yellow protein.
Biochemistry, 39, 2000
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4LS8
 | | Crystal structure of Bacillus subtilis beta-ketoacyl-ACP synthase II (FabF) in a covalent complex with cerulenin | | 分子名称: | (3R,7E,10E)-3-hydroxy-4-oxododeca-7,10-dienamide, 1,2-ETHANEDIOL, 3-oxoacyl-[acyl-carrier-protein] synthase 2, ... | | 著者 | Trajtenberg, F, Larrieux, N, Buschiazzo, A. | | 登録日 | 2013-07-22 | | 公開日 | 2014-04-02 | | 最終更新日 | 2014-06-04 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Structural insights into bacterial resistance to cerulenin.
Febs J., 281, 2014
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1RCV
 | | Cholera Toxin B-Pentamer Complexed With Bivalent Nitrophenol-Galactoside Ligand BV1 | | 分子名称: | [3-(4-{3-[3-NITRO-5-(GALACTOPYRANOSYLOXY)-BENZOYLAMINO]-PROPYL}-PIPERAZIN-1-YL)-PROPYLAMINO] -2-(3-{4-[3-(3-NITRO-5-[GALACTOPYRANOSYLOXY]-BENZOYLAMINO)-PROPYL]-PIPERAZIN-1-YL} -PROPYL-AMINO)-3,4-DIOXO-CYCLOBUTENE, cholera toxin B protein (CTB) | | 著者 | Pickens, J.C, Mitchell, D.D, Liu, J, Tan, X, Zhang, Z, Verlinde, C.L, Hol, W.G, Fan, E. | | 登録日 | 2003-11-04 | | 公開日 | 2004-10-26 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Nonspanning bivalent ligands as improved surface receptor binding inhibitors of the cholera toxin B pentamer.
Chem.Biol., 11, 2004
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5FA0
 | | The structure of the beta-3-deoxy-D-manno-oct-2-ulosonic acid transferase domain from WbbB | | 分子名称: | CHLORIDE ION, Putative N-acetyl glucosaminyl transferase | | 著者 | Mallette, E, Ovchinnikova, O.G, Whitfield, C, Kimber, M.S. | | 登録日 | 2015-12-10 | | 公開日 | 2016-05-18 | | 最終更新日 | 2018-04-25 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Bacterial beta-Kdo glycosyltransferases represent a new glycosyltransferase family (GT99).
Proc. Natl. Acad. Sci. U.S.A., 113, 2016
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1P2R
 | | T4 LYSOZYME CORE REPACKING MUTANT I78V/TA | | 分子名称: | 2-HYDROXYETHYL DISULFIDE, CHLORIDE ION, LYSOZYME, ... | | 著者 | Mooers, B.H, Datta, D, Baase, W.A, Zollars, E.S, Mayo, S.L, Matthews, B.W. | | 登録日 | 2003-04-15 | | 公開日 | 2003-10-07 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (1.58 Å) | | 主引用文献 | Repacking the Core of T4 lysozyme by automated design
J.Mol.Biol., 332, 2003
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1RF8
 | | Solution structure of the yeast translation initiation factor eIF4E in complex with m7GDP and eIF4GI residues 393 to 490 | | 分子名称: | 7N-METHYL-8-HYDROGUANOSINE-5'-DIPHOSPHATE, Eukaryotic initiation factor 4F subunit p150, Eukaryotic translation initiation factor 4E, ... | | 著者 | Gross, J.D, Moerke, N.J, von der Haar, T, Lugovskoy, A.A, Sachs, A.B, McCarthy, J.E.G, Wagner, G. | | 登録日 | 2003-11-07 | | 公開日 | 2003-12-23 | | 最終更新日 | 2024-03-06 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Ribosome loading onto the mRNA cap is driven by conformational coupling between eIF4G and eIF4E.
Cell(Cambridge,Mass.), 115, 2003
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1BVA
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7F4B
 | | The crystal structure of the immature apo-enzyme of homoserine dehydrogenase from the hyperthermophilic archaeon Sulfurisphaera tokodaii. | | 分子名称: | MAGNESIUM ION, homoserine dehydrogenase | | 著者 | Kurihara, E, Kubota, T, Watanabe, K, Ogata, K, Kaneko, R, Oshima, T, Yoshimune, K, Goto, M. | | 登録日 | 2021-06-18 | | 公開日 | 2022-06-22 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | | 主引用文献 | Conformational changes in the catalytic region are responsible for heat-induced activation of hyperthermophilic homoserine dehydrogenase.
Commun Biol, 5, 2022
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1RD9
 | | Cholera Toxin B-Pentamer Complexed With Bivalent Nitrophenol-Galactoside Ligand BV2 | | 分子名称: | 1,3-BIS-([3-(4-{3-[3-NITRO-5-(GALACTOPYRANOSYLOXY)-BENZOYLAMINO]-PROPYL}-PIPERAZIN-1-YL)-PROPYL-AMINO]-CARBONYLOXY)-2-AMINO-PROPANE, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, HEXAETHYLENE GLYCOL, ... | | 著者 | Pickens, J.C, Mitchell, D.D, Liu, J, Tan, X, Zhang, Z, Verlinde, C.L, Hol, W.G, Fan, E. | | 登録日 | 2003-11-05 | | 公開日 | 2004-10-26 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (1.44 Å) | | 主引用文献 | Nonspanning bivalent ligands as improved surface receptor binding inhibitors of the cholera toxin B pentamer.
Chem.Biol., 11, 2004
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4LYL
 | | Crystal structure of uracil-DNA glycosylase from cod (Gadus morhua) in complex with the proteinaceous inhibitor UGI | | 分子名称: | Uracil-DNA glycosylase, Uracil-DNA glycosylase inhibitor | | 著者 | Assefa, N.G, Niiranen, L.M.K, Johnson, K.A, Leiros, H.-K.S, Smalas, A.O, Willassen, N.P, Moe, E. | | 登録日 | 2013-07-31 | | 公開日 | 2014-08-13 | | 実験手法 | X-RAY DIFFRACTION (1.93 Å) | | 主引用文献 | Structural and biophysical analysis of interactions between cod and human uracil-DNA N-glycosylase (UNG) and UNG inhibitor (Ugi).
Acta Crystallogr.,Sect.D, 70, 2014
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1BSQ
 | | STRUCTURAL AND FUNCTIONAL CONSEQUENCES OF POINT MUTATIONS OF VARIANTS A AND B OF BOVINE BETA-LACTOGLOBULIN | | 分子名称: | PROTEIN (BETA-LACTOGLOBULIN) | | 著者 | Qin, B.Y, Creamer, L.K, Bewley, M.C, Baker, E.N, Jameson, G.B. | | 登録日 | 1998-08-29 | | 公開日 | 1998-09-02 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2.22 Å) | | 主引用文献 | Functional implications of structural differences between variants A and B of bovine beta-lactoglobulin.
Protein Sci., 8, 1999
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2HYQ
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3NG9
 | | Structure to Function Correlations for Adeno-associated Virus Serotype 1 | | 分子名称: | 6-AMINOPYRIMIDIN-2(1H)-ONE, ADENINE, Capsid protein | | 著者 | Govindasamy, L, Miller, E.B, Gurda, B, McKenna, R, Zolotukhin, S, Muzyczka, N, Agbandje-McKenna, M. | | 登録日 | 2010-06-11 | | 公開日 | 2011-12-21 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Structure to Function Correlations for Adeno-Associated Virus serotype 1
To be Published
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4M0R
 | | Trianthranilate-like analogue bound to anthranilate phosphoribosyltransferase (AnPRT; TrpD). | | 分子名称: | 2,6-bis[(2-carboxyphenyl)amino]benzoic acid, Anthranilate phosphoribosyltransferase, DIMETHYL SULFOXIDE, ... | | 著者 | Evans, G.L, Baker, E.N, Lott, J.S, TB Structural Genomics Consortium (TBSGC) | | 登録日 | 2013-08-02 | | 公開日 | 2014-05-21 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (1.96 Å) | | 主引用文献 | Repurposing the Chemical Scaffold of the Anti-Arthritic Drug Lobenzarit to Target Tryptophan Biosynthesis in Mycobacterium tuberculosis.
Chembiochem, 15, 2014
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5FFN
 | | Complex of subtilase SubTY from Bacillus sp. TY145 with chymotrypsin inhibitor CI2A | | 分子名称: | CALCIUM ION, Enzyme subtilase SubTY from Bacillus sp. TY145, SODIUM ION, ... | | 著者 | McAuley, K.E, Svendsen, A, Oestergaard, P.R, Dohnalek, J, Wilson, K.S. | | 登録日 | 2015-12-18 | | 公開日 | 2016-05-18 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Stabilization of Enzymes by Metal Binding: Structures of Two Alkalophilic Bacillus Subtilases and Analysis of the Second Metal-Binding Site of the Subtilase Family
Book, 2016
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3NJO
 | | X-ray crystal structure of the Pyr1-pyrabactin A complex | | 分子名称: | 4-bromo-N-(pyridin-2-ylmethyl)naphthalene-1-sulfonamide, Abscisic acid receptor PYR1, CHLORIDE ION, ... | | 著者 | Burgie, E.S, Bingman, C.A, Phillips Jr, G.N, Peterson, F.C, Volkman, B.F, Cutler, S.R, Jensen, D.R, Center for Eukaryotic Structural Genomics (CESG) | | 登録日 | 2010-06-17 | | 公開日 | 2010-08-18 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2.473 Å) | | 主引用文献 | Structural basis for selective activation of ABA receptors.
Nat.Struct.Mol.Biol., 17, 2010
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3T3Z
 | | Human Cytochrome P450 2E1 in complex with pilocarpine | | 分子名称: | (3S,4R)-3-ethyl-4-[(1-methyl-1H-imidazol-5-yl)methyl]dihydrofuran-2(3H)-one, Cytochrome P450 2E1, PROTOPORPHYRIN IX CONTAINING FE, ... | | 著者 | Meneely, K.M, DeVore, N.M, Scott, E.E. | | 登録日 | 2011-07-25 | | 公開日 | 2011-12-07 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | | 主引用文献 | Structural comparison of cytochromes P450 2A6, 2A13, and 2E1 with pilocarpine.
Febs J., 279, 2012
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7JZJ
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1W8H
 | | structure of pseudomonas aeruginosa lectin II (PA-IIL)complexed with lewisA trisaccharide | | 分子名称: | CALCIUM ION, GLYCEROL, PSEUDOMONAS AERUGINOSA LECTIN II, ... | | 著者 | Perret, S, Sabin, C, Dumon, C, Budova, M, Gautier, C, Galanina, O, Ilia, S, Bovin, N, Nicaise, M, Desmadril, M, Gilboa-Garber, N, Wimmerova, M, Mitchell, E.P, Imberty, A. | | 登録日 | 2004-09-21 | | 公開日 | 2005-03-31 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | | 主引用文献 | Structural Basis for the Interaction between Human Milk Oligosaccharides and the Bacterial Lectin Pa-Iil of Pseudomonas Aeruginosa.
Biochem.J., 389, 2005
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1BVJ
 | | HIV-1 RNA A-RICH HAIRPIN LOOP | | 分子名称: | RNA (5'-R(P*GP*GP*CP*GP*AP*CP*GP*GP*UP*GP*UP*AP*AP*AP*AP*AP*UP*CP*UP*CP*GP*CP* C)-3') | | 著者 | Puglisi, E.V, Puglisi, J.D. | | 登録日 | 1998-08-31 | | 公開日 | 1998-12-09 | | 最終更新日 | 2024-05-22 | | 実験手法 | SOLUTION NMR | | 主引用文献 | HIV-1 A-rich RNA loop mimics the tRNA anticodon structure.
Nat.Struct.Biol., 5, 1998
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5WPN
 | | Zn-bound Structure of Chaetopterus variopedatus Ferritin | | 分子名称: | 1,2-ETHANEDIOL, CALCIUM ION, CHLORIDE ION, ... | | 著者 | De Meulenaere, E, Bailey, J.B, Tezcan, F.A, Deheyn, D. | | 登録日 | 2017-08-05 | | 公開日 | 2017-12-06 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (1.57 Å) | | 主引用文献 | First biochemical and crystallographic characterization of a fast-performing ferritin from a marine invertebrate.
Biochem. J., 474, 2017
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5T0O
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5FT6
 | | Crystal structure of the cysteine desulfurase CsdA (S-sulfonic acid) from Escherichia coli at 2.050 Angstroem resolution | | 分子名称: | CYSTEINE DESULFURASE CSDA, DI(HYDROXYETHYL)ETHER, GLYCEROL, ... | | 著者 | Fernandez, F.J, Arda, A, Lopez-Estepa, M, Aranda, J, Penya-Soler, E, Garces, F, Round, A, Campos-Oliva, R, Bruix, M, Coll, M, Tunon, I, Jimenez-Barbero, J, Vega, M.C. | | 登録日 | 2016-01-11 | | 公開日 | 2016-11-23 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2.049 Å) | | 主引用文献 | Mechanism of Sulfur Transfer Across Protein-Protein Interfaces: The Cysteine Desulfurase Model System
Acs Catalysis, 6, 2016
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7F4X
 | | Joint neutron and X-ray crystal structure of the nucleotide-binding domain of Hsp72 in complex with ADP | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Heat shock 70 kDa protein 1B, MAGNESIUM ION, ... | | 著者 | Yokoyama, T, Ostermann, A, Schrader, T.E. | | 登録日 | 2021-06-21 | | 公開日 | 2022-06-29 | | 最終更新日 | 2024-04-03 | | 実験手法 | NEUTRON DIFFRACTION (1.6 Å), X-RAY DIFFRACTION | | 主引用文献 | Neutron crystallographic analysis of the nucleotide-binding domain of Hsp72 in complex with ADP.
Iucrj, 9, 2022
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