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1TYN
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ATOMIC STRUCTURE OF THE TRYPSIN-CYCLOTHEONAMIDE A COMPLEX: LESSONS FOR THE DESIGN OF SERINE PROTEASE INHIBITORS
分子名称: BETA-TRYPSIN, CYCLOTHEONAMIDE A
著者Lee, A.Y, Hagihara, M, Karmacharya, R, Albers, M.W, Schreiber, S.L, Clardy, J.
登録日1994-09-19
公開日1995-01-26
最終更新日2024-06-05
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Atomic Structure of the Trypsin-Cyclotheonamide a Complex: Lessons for the Design of Serine Protease Inhibitors
J.Am.Chem.Soc., 115, 1993
2KLI
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Structural Basis for the Photoconversion of A Phytochrome to the Activated FAR-RED LIGHT-ABSORBING Form
分子名称: PHYCOCYANOBILIN, Sensor protein
著者Cornilescu, C.C, Cornilescu, G, Ulijasz, A.T, Zhang, J, Rivera, M, Vierstra, R.D, Markley, J.L, Center for Eukaryotic Structural Genomics (CESG)
登録日2009-07-03
公開日2009-11-03
最終更新日2022-03-16
実験手法SOLUTION NMR
主引用文献Structural basis for the photoconversion of a phytochrome to the activated Pfr form
Nature, 463, 2010
2CE2
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CRYSTAL STRUCTURE ANALYSIS OF A FLUORESCENT FORM OF H-RAS P21 IN COMPLEX WITH GDP
分子名称: GTPASE HRAS, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ...
著者Klink, B.U, Goody, R.S, Scheidig, A.J.
登録日2006-02-02
公開日2006-08-23
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1 Å)
主引用文献A Newly Designed Microspectrofluorometer for Kinetic Studies on Protein Crystals in Combination with X-Ray Diffraction
Biophys.J., 91, 2006
2E2R
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Crystal structure of human estrogen-related receptor gamma ligand binding domain complex with bisphenol A
分子名称: 4,4'-PROPANE-2,2-DIYLDIPHENOL, Estrogen-related receptor gamma, GLYCEROL
著者Matsushima, A, Kakuta, Y, Teramoto, T, Koshiba, T, Kimura, M, Shimohigashi, Y.
登録日2006-11-16
公開日2007-09-11
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Structural Evidence for Endocrine Disruptor Bisphenol A Binding to Human Nuclear Receptor ERR{gamma}
J.Biochem.(Tokyo), 142, 2007
1JEG
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Solution structure of the SH3 domain from C-terminal Src Kinase complexed with a peptide from the tyrosine phosphatase PEP
分子名称: HEMATOPOIETIC CELL PROTEIN-TYROSINE PHOSPHATASE 70Z-PEP, TYROSINE-PROTEIN KINASE CSK
著者Ghose, R, Shekhtman, A, Goger, M.J, Ji, H, Cowburn, D.
登録日2001-06-17
公開日2001-10-31
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献A novel, specific interaction involving the Csk SH3 domain and its natural ligand.
Nat.Struct.Biol., 8, 2001
2B58
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SSAT with coa_sp, spermine disordered, K26R mutant
分子名称: COENZYME A, Diamine acetyltransferase 1
著者Bewley, M.C, Graziano, V, Jiang, J.S, Matz, E, Studier, F.W, Pegg, A.P, Coleman, C.S, Flanagan, J.M, Burley, S.K, New York SGX Research Center for Structural Genomics (NYSGXRC)
登録日2005-09-27
公開日2006-01-24
最終更新日2021-02-03
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Structures of wild-type and mutant human spermidine/spermine N1-acetyltransferase, a potential therapeutic drug target
Proc.Natl.Acad.Sci.Usa, 103, 2006
2B4D
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SSAT+COA+SP- SP disordered
分子名称: COENZYME A, Diamine acetyltransferase 1
著者Bewley, M.C, Graziano, V, Jiang, J.S, Matz, E, Studier, F.W, Pegg, A.P, Coleman, C.S, Flanagan, J.M, Burley, S.K, New York SGX Research Center for Structural Genomics (NYSGXRC)
登録日2005-09-23
公開日2006-01-17
最終更新日2021-02-03
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structures of wild-type and mutant human spermidine/spermine N1-acetyltransferase, a potential therapeutic drug target
Proc.Natl.Acad.Sci.Usa, 103, 2006
2B3V
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Spermine spermidine acetyltransferase in complex with acetylcoa, K26R mutant
分子名称: ACETYL COENZYME *A, Diamine acetyltransferase 1
著者Bewley, M.C, Graziano, V, Jiang, J.S, Matz, E, Studier, F.W, Pegg, A.P, Coleman, C.S, Flanagan, J.M, Burley, S.K, New York SGX Research Center for Structural Genomics (NYSGXRC)
登録日2005-09-21
公開日2006-01-17
最終更新日2021-02-03
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Structures of wild-type and mutant human spermidine/spermine N1-acetyltransferase, a potential therapeutic drug target.
Proc.Natl.Acad.Sci.USA, 103, 2006
2B4B
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SSAT+COA+BE-3-3-3, K26R mutant
分子名称: COENZYME A, Diamine acetyltransferase 1, N-ETHYL-N-[3-(PROPYLAMINO)PROPYL]PROPANE-1,3-DIAMINE
著者Bewley, M.C, Graziano, V, Jiang, J.S, Matz, E, Studier, F.W, Pegg, A.P, Coleman, C.S, Flanagan, J.M, Burley, S.K, New York SGX Research Center for Structural Genomics (NYSGXRC)
登録日2005-09-23
公開日2006-01-17
最終更新日2023-05-24
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structures of wild-type and mutant human spermidine/spermine N1-acetyltransferase, a potential therapeutic drug target
Proc.Natl.Acad.Sci.Usa, 103, 2006
2CS7
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1.2 A Crystal structure of the S. pneumoniae PhtA histidine triad domain a novel zinc binding fold
分子名称: ZINC ION, pneumococcal histidine triad A protein
著者Riboldi-Tunnicliffe, A, Isaacs, N.W, Mitchell, T.J.
登録日2005-05-20
公開日2006-02-14
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.2 Å)
主引用文献1.2 Angstroms crystal structure of the S. pneumoniae PhtA histidine triad domain a novel zinc binding fold.
Febs Lett., 579, 2005
2LB5
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Refined Structural Basis for the Photoconversion of A Phytochrome to the Activated FAR-RED LIGHT-ABSORBING Form
分子名称: PHYCOCYANOBILIN, Sensor histidine kinase
著者Cornilescu, C.C, Cornilescu, G, Ulijasz, A.T, Vierstra, R.D, Markley, J.L.
登録日2011-03-23
公開日2011-06-29
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Structural basis for the photoconversion of a phytochrome to the activated Pfr form.
Nature, 463, 2010
3U6T
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Crystal structure of the complex of type I Ribosome inactivating protein in complex with Kanamycin at 1.85 A
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, KANAMYCIN A, ...
著者Yamini, S, Pandey, S, Kushwaha, G.S, Sinha, M, Bhushan, A, Kaur, P, Sharma, S, Singh, T.P.
登録日2011-10-13
公開日2011-11-16
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Crystal structure of the complex of type I Ribosome inactivating protein in complex with Kanamycin at 1.85 A
To be Published
2EZV
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Crystal structure of tetrameric restriction endonuclease SfiI bound to cognate DNA.
分子名称: 5'-D(*AP*GP*GP*CP*CP*TP*TP*GP*TP*TP*GP*GP*CP*CP*A)-3', 5'-D(*TP*GP*GP*CP*CP*AP*AP*CP*AP*AP*GP*GP*CP*CP*T)-3', CALCIUM ION, ...
著者Aggarwal, A.K, Vanamee, E.S, Viadiu, H.
登録日2005-11-10
公開日2006-01-24
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献A view of consecutive binding events from structures of tetrameric endonuclease SfiI bound to DNA
Embo J., 24, 2005
2EWJ
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Escherichia Coli Replication Terminator Protein (Tus) Complexed With DNA- Locked form
分子名称: 5'-D(*T*TP*AP*GP*TP*TP*AP*CP*AP*AP*CP*AP*TP*AP*CP*T)-3', 5'-D(*TP*G*AP*TP*AP*TP*GP*TP*TP*GP*TP*AP*AP*CP*TP*A)-3', DNA replication terminus site-binding protein, ...
著者Oakley, A.J, Mulcair, M.D, Schaeffer, P.M, Dixon, N.E.
登録日2005-11-03
公開日2006-05-03
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献A molecular mousetrap determines polarity of termination of DNA replication in E. coli.
Cell(Cambridge,Mass.), 125, 2006
2CTB
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THE HIGH RESOLUTION CRYSTAL STRUCTURE OF THE COMPLEX BETWEEN CARBOXYPEPTIDASE A AND L-PHENYL LACTATE
分子名称: CARBOXYPEPTIDASE A, ZINC ION
著者Teplyakov, A, Wilson, K.S, Orioli, P, Mangani, S.
登録日1993-04-02
公開日1994-01-31
最終更新日2017-11-29
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献High-resolution structure of the complex between carboxypeptidase A and L-phenyl lactate.
Acta Crystallogr.,Sect.D, 49, 1993
2OVM
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Progesterone Receptor with Bound Asoprisnil and a Peptide from the Co-Repressor NCoR
分子名称: 4-[(11BETA,17BETA)-17-METHOXY-17-(METHOXYMETHYL)-3-OXOESTRA-4,9-DIEN-11-YL]BENZALDEHYDE OXIME, NCoR, Progesterone receptor
著者Madauss, K.P, Deng, S.-J, Short, S.A, Stewart, E.L, Williams, S.P.
登録日2007-02-14
公開日2007-03-20
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献A structural and in vitro characterization of asoprisnil: a selective progesterone receptor modulator.
Mol.Endocrinol., 21, 2007
2N70
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Two-fold symmetric structure of the 18-60 construct of S31N M2 from Influenza A in lipid bilayers
分子名称: Matrix protein 2
著者Andreas, L.B, Reese, M, Eddy, M.T, Gelev, V, Ni, Q, Miller, E.A, Emsley, L, Pintacuda, G, Chou, J.J, Griffin, R.G.
登録日2015-09-01
公開日2015-09-23
最終更新日2024-05-15
実験手法SOLID-STATE NMR
主引用文献Structure and Mechanism of the Influenza A M218-60 Dimer of Dimers.
J.Am.Chem.Soc., 137, 2015
2CTC
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THE HIGH RESOLUTION CRYSTAL STRUCTURE OF THE COMPLEX BETWEEN CARBOXYPEPTIDASE A AND L-PHENYL LACTATE
分子名称: ALPHA-HYDROXY-BETA-PHENYL-PROPIONIC ACID, CARBOXYPEPTIDASE A, ZINC ION
著者Teplyakov, A, Wilson, K.S, Orioli, P, Mangani, S.
登録日1993-04-02
公開日1994-01-31
最終更新日2017-11-29
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献High-resolution structure of the complex between carboxypeptidase A and L-phenyl lactate.
Acta Crystallogr.,Sect.D, 49, 1993
2N17
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NMR structure of a Kazal-type serine protease inhibitor from the subterranean termite defense gland of Coptotermes formosanus Shiraki soldiers
分子名称: Lysozyme-Protease Inhibitor Protein
著者Negulescu, H, Guo, Y, Garner, T.P, Goodwin, O.Y, Henderson, G, Laine, R.A, Macnaughtan, M.A.
登録日2015-03-23
公開日2015-05-06
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献A Kazal-Type Serine Protease Inhibitor from the Defense Gland Secretion of the Subterranean Termite Coptotermes formosanus Shiraki.
Plos One, 10, 2015
2HWN
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Crystal Structure of RII alpha Dimerization/Docking domain of PKA bound to the D-AKAP2 peptide
分子名称: A Kinase binding peptide, GLYCEROL, cAMP-dependent protein kinase type II-alpha regulatory subunit
著者Kinderman, F, Kim, C.
登録日2006-08-01
公開日2006-11-21
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献A Dynamic Mechanism for AKAP Binding to RII Isoforms of cAMP-Dependent Protein Kinase.
Mol.Cell, 24, 2006
2H67
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NMR structure of human insulin mutant HIS-B5-ALA, HIS-B10-ASP PRO-B28-LYS, LYS-B29-PRO, 20 structures
分子名称: Insulin A chain, Insulin B chain
著者Hua, Q.X, Liu, M, Hu, S.Q, Jia, W, Arvan, P, Weiss, M.A.
登録日2006-05-30
公開日2006-07-18
最終更新日2021-10-20
実験手法SOLUTION NMR
主引用文献A Conserved Histidine in Insulin Is Required for the Foldability of Human Proinsulin: Structure and function of an Alab5 analog.
J.Biol.Chem., 281, 2006
1N33
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Structure of the Thermus thermophilus 30S ribosomal subunit bound to codon and near-cognate transfer rna anticodon stem-loop mismatched at the second codon position at the a site with paromomycin
分子名称: 16S RIBOSOMAL RNA, 30S RIBOSOMAL PROTEIN S10, 30S RIBOSOMAL PROTEIN S11, ...
著者Ogle, J.M, Murphy IV, F.V, Tarry, M.J, Ramakrishnan, V.
登録日2002-10-25
公開日2002-11-29
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (3.35 Å)
主引用文献Selection of tRNA by the Ribosome Requires a Transition from an Open to a Closed Form
Cell(Cambridge,Mass.), 111, 2002
1VZK
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A Thiophene Based Diamidine Forms a "Super" AT Binding Minor Groove Agent
分子名称: 2-(5-{4-[AMINO(IMINO)METHYL]PHENYL}-2-THIENYL)-1H-BENZIMIDAZOLE-6- CARBOXIMIDAMIDE DIHYDROCHLORIDE, 5'-D(*CP*GP*CP*GP*AP*AP*TP*TP*CP*GP *CP*G)-3', MAGNESIUM ION
著者Mallena, S, Lee, M.P.H, Bailly, C, Neidle, S, Kumar, A, Boykin, D.W, Wilson, W.D.
登録日2004-05-20
公開日2004-10-25
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.77 Å)
主引用文献Thiophene-Based Diamidine Forms a "Super" at Binding Minor Groove Agent
J.Am.Chem.Soc., 142, 2004
1E8L
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NMR solution structure of hen lysozyme
分子名称: LYSOZYME
著者Schwalbe, H, Grimshaw, S.B, Spencer, A, Buck, M, Boyd, J, Dobson, C.M, Redfield, C, Smith, L.J.
登録日2000-09-27
公開日2000-10-09
最終更新日2018-01-24
実験手法SOLUTION NMR
主引用文献A refined solution structure of hen lysozyme determined using residual dipolar coupling data.
Protein Sci., 10, 2001
1N49
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Viability of a Drug-Resistant HIV-1 Protease Variant: Structural Insights for Better Anti-Viral Therapy
分子名称: Protease, RITONAVIR
著者Prabu-Jeyabalan, M, Nalivaika, E.A, King, N.M, Schiffer, C.A.
登録日2002-10-30
公開日2003-01-07
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Viability of a Drug-Resistant Human Immunodeficiency Virus Type 1 Protease Variant: Structural Insights for Better Antiviral Therapy
J.VIROL., 77, 2003

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