PDB: 5653 件ウェブページステータス検索Chemie searchBIRD

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4B8Z	Crystal structure of human GDP-L-fucose synthase with bound NADP and GDP, rhombohedral crystal form 分子名称: GDP-L-FUCOSE SYNTHASE, GUANOSINE-5'-DIPHOSPHATE, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE 著者 Vollmar, M, Krojer, T, Shafqat, N, Rojkova, A, Bunkoczi, G, Yue, W.W, Kavanagh, K, von Delft, F, Weigelt, J, Arrowsmith, C.H, Bountra, C, Edwards, A, Oppermann, U. 登録日 2012-08-31 公開日 2013-02-06 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.75 Å) 主引用文献 Crystal Structure of Human Gdp-L-Fucose Synthase with Bound Nadp and Gdp, Rhombohedral Crystal Form To be Published
6AQY	Crystal structure of a gdp-l-fucose synthetase from Naegleria fowleri 分子名称: CHLORIDE ION, SULFATE ION, gdp-l-fucose synthetase 著者 Seattle Structural Genomics Center for Infectious Disease, Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2017-08-21 公開日 2017-08-30 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.55 Å) 主引用文献 Crystal structure of a gdp-l-fucose synthetase from Naegleria fowleri To Be Published
6D61	Crystal structure of 3-hydroxyanthranilate-3,4-dioxygenase I142P from Cupriavidus metallidurans in complex with 4-Cl-3-HAA 分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 3-hydroxyanthranilate 3,4-dioxygenase, 4-CHLORO-3-HYDROXYANTHRANILIC ACID, ... 著者 Yang, Y, Liu, F, Liu, A. 登録日 2018-04-19 公開日 2018-06-06 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.74 Å) 主引用文献 Adapting to oxygen: 3-Hydroxyanthrinilate 3,4-dioxygenase employs loop dynamics to accommodate two substrates with disparate polarities. J. Biol. Chem., 293, 2018
6DPR	Mapping the binding trajectory of a suicide inhibitor in human indoleamine 2,3-dioxygenase 1 分子名称: (2R)-N-(4-chlorophenyl)-2-[cis-4-(6-fluoroquinolin-4-yl)cyclohexyl]propanamide, 1,2-ETHANEDIOL, Indoleamine 2,3-dioxygenase 1, ... 著者 Pham, K.N, Yeh, S.R. 登録日 2018-06-09 公開日 2018-11-07 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 Mapping the Binding Trajectory of a Suicide Inhibitor in Human Indoleamine 2,3-Dioxygenase 1. J. Am. Chem. Soc., 140, 2018
6D6S	Solution structure of Trigger Factor dimer 分子名称: Trigger factor 著者 Saio, T, Kawagoe, S, Ishimori, K, Kalodimos, C.G. 登録日 2018-04-22 公開日 2018-06-13 最終更新日 2024-05-01 実験手法 SOLUTION NMR 主引用文献 Oligomerization of a molecular chaperone modulates its activity. Elife, 7, 2018
4B4K	Crystal structure of Bacillus anthracis PurE 分子名称: N5-CARBOXYAMINOIMIDAZOLE RIBONUCLEOTIDE MUTASE 著者 Oliete, R, Pous, J, Rodriguez-Puente, S, Abad-Zapatero, C, Guasch, A. 登録日 2012-07-31 公開日 2012-08-08 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Elastic and Inelastic Diffraction Changes Upon Variation of the Relative Humidity Environment of Pure Crystals Acta Crystallogr.,Sect.D, 69, 2013
4BKP	Crystal structure of human GDP-L-fucose synthase with bound NADP 分子名称: 1,2-ETHANEDIOL, CITRATE ANION, GDP-L-FUCOSE SYNTHASE, ... 著者 Vollmar, M, Shafqat, N, Rojkova, A, Krojer, T, Bradley, A, Raynor, J.W, Kavanagh, K, von Delft, F, Arrowsmith, C.H, Bountra, C, Edwards, A, Oppermann, U, Yue, W.W. 登録日 2013-04-29 公開日 2013-06-12 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Crystal Structure of Human Gdp-L-Fucose Synthase with Bound Nadp To be Published
5ILN	Crystal structure of Aspartate Transcarbamoylase from Plasmodium falciparum (PfATC) with bound citrate 分子名称: Aspartate carbamoyltransferase, CITRATE ANION, GLYCEROL, ... 著者 Lunev, S, Bosch, S.S, Batista, F.D.A, Wrenger, C, Groves, M.R. 登録日 2016-03-04 公開日 2017-03-29 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (2.21 Å) 主引用文献 Crystal structure of truncated Aspartate Transcarbamoylase from Plasmodium falciparum To be published
6X5Y	IDO1 in complex with compound 4 分子名称: 4-fluoro-N-{1-[5-(2-methylpyrimidin-4-yl)-5,6,7,8-tetrahydro-1,5-naphthyridin-2-yl]cyclopropyl}benzamide, Indoleamine 2,3-dioxygenase 1 著者 Lesburg, C.A, Lammens, A. 登録日 2020-05-27 公開日 2021-06-02 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.65 Å) 主引用文献 Utilization of MetID and Structural Data to Guide Placement of Spiro and Fused Cyclopropyl Groups for the Synthesis of Low Dose IDO1 Inhibitors To Be Published
5OWJ	The dynamic dimer structure of the chaperone Trigger Factor (conformer 2) 分子名称: Trigger factor 著者 Morgado, L, Burmann, B.M, Sharpe, T, Mazur, A, Hiller, S. 登録日 2017-09-01 公開日 2017-11-29 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 The dynamic dimer structure of the chaperone Trigger Factor. Nat Commun, 8, 2017
4M0G	The crystal structure of an adenylosuccinate synthetase from Bacillus anthracis str. Ames Ancestor. 分子名称: Adenylosuccinate synthetase, CHLORIDE ION 著者 Tan, K, Zhou, M, Zhang, R, Kwon, K, Anderson, W.F, Joachimiak, A, Midwest Center for Structural Genomics (MCSG), Center for Structural Genomics of Infectious Diseases (CSGID) 登録日 2013-08-01 公開日 2013-08-14 実験手法 X-RAY DIFFRACTION (2.152 Å) 主引用文献 The crystal structure of an adenylosuccinate synthetase from Bacillus anthracis str. Ames Ancestor. To be Published
4M3P	Betaine-Homocysteine S-Methyltransferase from Homo sapiens complexed with Homocysteine 分子名称: 2-AMINO-4-MERCAPTO-BUTYRIC ACID, Betaine--homocysteine S-methyltransferase 1, POTASSIUM ION, ... 著者 Koutmos, M, Yamada, K, Mladkova, J, Paterova, J, Diamond, C.E, Tryon, K, Jungwirth, P, Garrow, T.A, Jiracek, J. 登録日 2013-08-06 公開日 2014-06-18 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.895 Å) 主引用文献 Specific potassium ion interactions facilitate homocysteine binding to betaine-homocysteine S-methyltransferase. Proteins, 82, 2014
6SB2	cryo-EM structure of mTORC1 bound to active RagA/C GTPases 分子名称: GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, Ras-related GTP-binding protein A, ... 著者 Anandapadamanaban, M, Berndt, A, Masson, G.R, Perisic, O, Williams, R.L. 登録日 2019-07-18 公開日 2019-10-16 最終更新日 2024-05-22 実験手法 ELECTRON MICROSCOPY (6.2 Å) 主引用文献 Architecture of human Rag GTPase heterodimers and their complex with mTORC1. Science, 366, 2019
5IN5	Crystal Structure of GDP-mannose 4,6 dehydratase in complex with natural inhibitor GDP-Fucose 分子名称: GDP-mannose 4,6 dehydratase, GLYCEROL, GUANOSINE-5'-DIPHOSPHATE, ... 著者 Sickmier, E.A. 登録日 2016-03-07 公開日 2016-08-17 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Facile Modulation of Antibody Fucosylation with Small Molecule Fucostatin Inhibitors and Cocrystal Structure with GDP-Mannose 4,6-Dehydratase. Acs Chem.Biol., 11, 2016
4LGY	Importance of Hydrophobic Cavities in Allosteric Regulation of Formylglycinamide Synthetase: Insight from Xenon Trapping and Statistical Coupling Analysis 分子名称: ACETATE ION, ADENOSINE-5'-DIPHOSPHATE, CHLORIDE ION, ... 著者 Tanwar, A.S, Goyal, V.D, Choudhary, D, Panjikar, S, Anand, R. 登録日 2013-06-30 公開日 2013-12-11 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.48 Å) 主引用文献 Importance of hydrophobic cavities in allosteric regulation of formylglycinamide synthetase: insight from xenon trapping and statistical coupling analysis Plos One, 8, 2013
4L6O	Crystal structure of the Candida albicans Methionine Synthase in complex with Glutamine 分子名称: 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase, GLUTAMINE, ZINC ION 著者 Ubhi, D, Robertus, J.D. 登録日 2013-06-12 公開日 2014-03-05 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.88 Å) 主引用文献 Structural analysis of a fungal methionine synthase with substrates and inhibitors. J.Mol.Biol., 426, 2014
4L2N	Understanding Extradiol Dioxygenase Mechanism in NAD+ Biosynthesis by Viewing Catalytic Intermediates - ligand-free structure 分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 3-hydroxyanthranilate 3,4-dioxygenase, CHLORIDE ION, ... 著者 Liu, F, Liu, A. 登録日 2013-06-04 公開日 2015-05-06 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.74 Å) 主引用文献 An Iron Reservoir to the Catalytic Metal: THE RUBREDOXIN IRON IN AN EXTRADIOL DIOXYGENASE. J.Biol.Chem., 290, 2015
4L64	Crystal structure of the Candida albicans Methionine Synthase in complex with 5-Methyl-Tetrahydrofolate 分子名称: 5-METHYL-5,6,7,8-TETRAHYDROFOLIC ACID, 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase, ZINC ION 著者 Ubhi, D, Robertus, J.D. 登録日 2013-06-11 公開日 2014-03-05 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.18 Å) 主引用文献 Structural analysis of a fungal methionine synthase with substrates and inhibitors. J.Mol.Biol., 426, 2014
5TK5	Crystal structure of human 3HAO with iron bound in the active site 分子名称: 3-hydroxyanthranilate 3,4-dioxygenase, FE (III) ION, SULFATE ION 著者 Pidugu, L.S, Toth, E.A. 登録日 2016-10-06 公開日 2017-04-12 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.88 Å) 主引用文献 Crystal structures of human 3-hydroxyanthranilate 3,4-dioxygenase with native and non-native metals bound in the active site. Acta Crystallogr D Struct Biol, 73, 2017
6SB0	cryo-EM structure of mTORC1 bound to PRAS40-fused active RagA/C GTPases 分子名称: GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, Proline-rich AKT1 substrate 1, ... 著者 Anandapadamanaban, M, Berndt, A, Masson, G.R, Perisic, O, Williams, R.L. 登録日 2019-07-18 公開日 2019-10-16 最終更新日 2024-05-22 実験手法 ELECTRON MICROSCOPY (5.5 Å) 主引用文献 Architecture of human Rag GTPase heterodimers and their complex with mTORC1. Science, 366, 2019
7PVO	Adenylosuccinate Synthetase from H. pylori in complex with IMP 分子名称: Adenylosuccinate synthetase, INOSINIC ACID, SULFATE ION 著者 Narczyk, M, Bzowska, A, Maksymiuk, W. 登録日 2021-10-05 公開日 2022-11-16 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 The pursuit of new alternative ways to eradicate Helicobacter pylori continues: Detailed characterization of interactions in the adenylosuccinate synthetase active site. Int.J.Biol.Macromol., 226, 2023
5TKV	X-RAY CRYSTAL STRUCTURE OF THE "CLOSED" CONFORMATION OF CTP-INHIBITED E. COLI CYTIDINE TRIPHOSPHATE (CTP) SYNTHETASE 分子名称: (4R)-2-METHYLPENTANE-2,4-DIOL, (4S)-2-METHYL-2,4-PENTANEDIOL, CTP synthase, ... 著者 Baldwin, E.P, Endrizzi, J.A. 登録日 2016-10-07 公開日 2017-04-26 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Human CTP synthase filament structure reveals the active enzyme conformation. Nat. Struct. Mol. Biol., 24, 2017
5U3C	CryoEM structure of the CTP synthase filament at 4.6 Angstrom resolution 分子名称: ADENOSINE-5'-DIPHOSPHATE, CTP synthase, CYTIDINE-5'-TRIPHOSPHATE 著者 Kollman, J.M, Lynch, E.M. 登録日 2016-12-01 公開日 2017-04-26 最終更新日 2017-06-21 実験手法 ELECTRON MICROSCOPY (4.6 Å) 主引用文献 Human CTP synthase filament structure reveals the active enzyme conformation. Nat. Struct. Mol. Biol., 24, 2017
7L7S	Human mitochondrial chaperonin mHsp60 分子名称: 60 kDa heat shock protein, mitochondrial 著者 Chen, L, Wang, J.C.Y. 登録日 2020-12-30 公開日 2021-08-25 最終更新日 2024-05-29 実験手法 ELECTRON MICROSCOPY (3.5 Å) 主引用文献 Structural basis for the structural dynamics of human mitochondrial chaperonin mHsp60. Sci Rep, 11, 2021
4L6H	Crystal structure of the Candida albicans Methionine Synthase in complex with Methotrexate and Homocysteine 分子名称: 2-AMINO-4-MERCAPTO-BUTYRIC ACID, 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase, METHOTREXATE, ... 著者 Ubhi, D, Robertus, J.D. 登録日 2013-06-12 公開日 2014-03-05 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Structural analysis of a fungal methionine synthase with substrates and inhibitors. J.Mol.Biol., 426, 2014

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