Importance of Hydrophobic Cavities in Allosteric Regulation of Formylglycinamide Synthetase: Insight from Xenon Trapping and Statistical Coupling Analysis

Summary for 4LGY

Related1T3T 3UMM 4L78 4MGH
DescriptorPhosphoribosylformylglycinamidine synthase, ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... (8 entities in total)
Functional Keywordsamido transferase, ligase
Biological sourceSalmonella typhimurium
Cellular locationCytoplasm (By similarity) P74881
Total number of polymer chains1
Total molecular weight145958.35
Tanwar, A.S.,Goyal, V.D.,Choudhary, D.,Panjikar, S.,Anand, R. (deposition date: 2013-06-30, release date: 2013-12-11)
Primary citation
Tanwar, A.S.,Goyal, V.D.,Choudhary, D.,Panjikar, S.,Anand, R.
Importance of hydrophobic cavities in allosteric regulation of formylglycinamide synthetase: insight from xenon trapping and statistical coupling analysis
Plos One, 8:e77781-e77781, 2013
PubMed: 24223728 (PDB entries with the same primary citation)
DOI: 10.1371/journal.pone.0077781
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.163100.2%1.7%2.5%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation reportDownload
PDB entries from 2020-07-29