PDB: 46200 件ウェブページステータス検索Chemie searchBIRD

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7TVB	Stat5A Core in Complex with AK305 分子名称: GLYCEROL, N-{5-[difluoro(phosphono)methyl]-1-benzothiophene-2-carbonyl}-3-methyl-L-valyl-L-prolyl-N,N-dimethyl-N~3~-[4-(1,3-thiazol-2-yl)phenyl]-beta-alaninamide, Signal transducer and activator of transcription 5A 著者 Meagher, J.L, Stuckey, J.A. 登録日 2022-02-04 公開日 2023-02-15 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.653 Å) 主引用文献 A selective small-molecule STAT5 PROTAC degrader capable of achieving tumor regression in vivo. Nat.Chem.Biol., 19, 2023
6LZ3	Structure of cryptochrome in active conformation 分子名称: Cryptochrome2, FLAVIN-ADENINE DINUCLEOTIDE 著者 Shao, K, Zhang, X, Zhang, P. 登録日 2020-02-18 公開日 2020-04-29 最終更新日 2020-11-11 実験手法 ELECTRON MICROSCOPY (3.2 Å) 主引用文献 The oligomeric structures of plant cryptochromes. Nat.Struct.Mol.Biol., 27, 2020
5B7A	SOLUTION STRUCTURE OF LYS37 ACETYLATED HUMAN SUMO1 分子名称: Small ubiquitin-related modifier 1 著者 Naik, M.T, Naik, N, Shih, H, Huang, T. 登録日 2016-06-05 公開日 2017-06-07 最終更新日 2023-11-15 実験手法 SOLUTION NMR 主引用文献 Structures Of Human Sumo To Be Published
8HJB	Crystal structure of Pseudomonas aeruginosa PvrA with coenzyme A 分子名称: COENZYME A, TetR family transcriptional regulator 著者 Liang, H, Bartlam, M. 登録日 2022-11-23 公開日 2023-02-08 最終更新日 2024-05-29 実験手法 X-RAY DIFFRACTION (2.65 Å) 主引用文献 Regulatory and structural mechanisms of PvrA-mediated regulation of the PQS quorum-sensing system and PHA biosynthesis in Pseudomonas aeruginosa. Nucleic Acids Res., 51, 2023
2MGN	Solution structure of a G-quadruplex bound to the bisquinolinium compound Phen-DC3 分子名称: 5'-D(*TP*GP*AP*GP*GP*GP*TP*GP*GP*TP*GP*AP*GP*GP*GP*TP*GP*GP*GP*GP*AP*AP*GP*G)-3', N2,N9-bis(1-methylquinolin-3-yl)-1,10-phenanthroline-2,9-dicarboxamide 著者 Chung, W.J, Heddi, B, Hamon, F, Teulade-Fichou, M.P, Phan, A.T. 登録日 2013-11-01 公開日 2014-01-22 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 Solution Structure of a G-quadruplex Bound to the Bisquinolinium Compound Phen-DC3. Angew.Chem.Int.Ed.Engl., 53, 2014
1RPW	Crystal Structure Of The Multidrug Binding Protein Qacr Bound To The Diamidine Hexamidine 分子名称: 4,4'[1,6-HEXANEDIYLBIS(OXY)]BISBENZENECARBOXIMIDAMIDE, SULFATE ION, Transcriptional regulator qacR 著者 Murray, D.S, Schumacher, M.A, Brennan, R.G. 登録日 2003-12-03 公開日 2004-06-01 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Crystal structures of QacR-diamidine complexes reveal additional multidrug-binding modes and a novel mechanism of drug charge neutralization. J.Biol.Chem., 279, 2004
7MYB	Structure of proline utilization A with tetrahydrothiophene-2-carboxylate bound in the proline dehydrogenase active site 分子名称: (2R)-thiolane-2-carboxylic acid, (2S)-thiolane-2-carboxylic acid, Bifunctional protein PutA, ... 著者 Tanner, J.J, Campbell, A.C. 登録日 2021-05-20 公開日 2021-09-29 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.52 Å) 主引用文献 Photoinduced Covalent Irreversible Inactivation of Proline Dehydrogenase by S-Heterocycles. Acs Chem.Biol., 16, 2021
7MY9	Structure of proline utilization A with 1,3-dithiolane-2-carboxylate bound in the proline dehydrogenase active site 分子名称: 1,3-dithiolane-2-carboxylic acid, Bifunctional protein PutA, DI(HYDROXYETHYL)ETHER, ... 著者 Tanner, J.J, Campbell, A.C. 登録日 2021-05-20 公開日 2021-09-29 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.628 Å) 主引用文献 Photoinduced Covalent Irreversible Inactivation of Proline Dehydrogenase by S-Heterocycles. Acs Chem.Biol., 16, 2021
7MYA	Structure of proline utilization A with the FAD covalently-modified by 1,3-dithiolane 分子名称: Bifunctional protein PutA, DI(HYDROXYETHYL)ETHER, MAGNESIUM ION, ... 著者 Tanner, J.J, Campbell, A.C. 登録日 2021-05-20 公開日 2021-09-29 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.56 Å) 主引用文献 Photoinduced Covalent Irreversible Inactivation of Proline Dehydrogenase by S-Heterocycles. Acs Chem.Biol., 16, 2021
7MYC	Structure of proline utilization A with the FAD covalently modified by tetrahydrothiophene 分子名称: 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, Bifunctional protein PutA, DI(HYDROXYETHYL)ETHER, ... 著者 Tanner, J.J, Campbell, A.C. 登録日 2021-05-20 公開日 2021-09-29 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Photoinduced Covalent Irreversible Inactivation of Proline Dehydrogenase by S-Heterocycles. Acs Chem.Biol., 16, 2021
1RKW	CRYSTAL STRUCTURE OF THE MULTIDRUG BINDING TRANSCRIPTIONAL REPRESSOR QACR BOUND TO PENTAMADINE 分子名称: 1,5-BIS(4-AMIDINOPHENOXY)PENTANE, SULFATE ION, Transcriptional regulator qacR 著者 Murray, D.S, Schumacher, M.A, Brennan, R.G. 登録日 2003-11-23 公開日 2004-06-01 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (2.62 Å) 主引用文献 Crystal structures of QacR-diamidine complexes reveal additional multidrug-binding modes and a novel mechanism of drug charge neutralization. J.Biol.Chem., 279, 2004
7NAU	Bacterial 30S ribosomal subunit assembly complex state C (Consensus Refinement) 分子名称: 16S rRNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ... 著者 Schedlbauer, A, Iturrioz, I, Ochoa-Lizarralde, B, Diercks, T, Kaminishi, T, Capuni, R, Astigarraga, E, Gil-Carton, D, Fucini, P, Connell, S. 登録日 2021-01-25 公開日 2021-12-08 最終更新日 2024-04-24 実験手法 ELECTRON MICROSCOPY (3.78 Å) 主引用文献 A conserved rRNA switch is central to decoding site maturation on the small ribosomal subunit. Sci Adv, 7, 2021
7NAT	Bacterial 30S ribosomal subunit assembly complex state A (Consensus refinement) 分子名称: 16S rRNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ... 著者 Schedlbauer, A, Iturrioz, I, Ochoa-Lizarralde, B, Diercks, T, Kaminishi, T, Capuni, R, Astigarraga, E, Gil-Carton, D, Fucini, P, Connell, S. 登録日 2021-01-25 公開日 2021-12-08 最終更新日 2024-04-24 実験手法 ELECTRON MICROSCOPY (3.59 Å) 主引用文献 A conserved rRNA switch is central to decoding site maturation on the small ribosomal subunit. Sci Adv, 7, 2021
7NAX	Complete Bacterial 30S ribosomal subunit assembly complex state I (Consensus Refinement) 分子名称: 16S rRNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ... 著者 Schedlbauer, A, Iturrioz, I, Ochoa-Lizarralde, B, Diercks, T, Lopez-Alonso, J, Kaminishi, T, Capuni, R, Astigarraga, E, Gil-Carton, D, Fucini, P, Connell, S. 登録日 2021-01-25 公開日 2021-12-08 最終更新日 2024-04-24 実験手法 ELECTRON MICROSCOPY (2.96 Å) 主引用文献 A conserved rRNA switch is central to decoding site maturation on the small ribosomal subunit. Sci Adv, 7, 2021
8BYA	Cryo-EM structure of SKP1-SKP2-CKS1-CDK2-CyclinA-p27KIP1 Complex 分子名称: Cyclin-A2, Cyclin-dependent kinase 2, Cyclin-dependent kinase inhibitor 1B, ... 著者 Rowland, R.J, Salamina, M, Endicott, J.A, Noble, M.E. 登録日 2022-12-12 公開日 2023-06-28 最終更新日 2023-07-19 実験手法 ELECTRON MICROSCOPY (3.38 Å) 主引用文献 Cryo-EM structure of SKP1-SKP2-CKS1 in complex with CDK2-cyclin A-p27KIP1. Sci Rep, 13, 2023
7NAR	Complete Bacterial 30S ribosomal subunit assembly complex state F (+RsgA)(Consensus Refinement) 分子名称: 16S rRNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ... 著者 Schedlbauer, A, Iturrioz, I, Ochoa-Lizarralde, B, Diercks, T, Kaminishi, T, Capuni, R, Astigarraga, E, Gil-Carton, D, Fucini, P, Connell, S. 登録日 2021-01-25 公開日 2021-12-08 最終更新日 2024-04-24 実験手法 ELECTRON MICROSCOPY (3 Å) 主引用文献 A conserved rRNA switch is central to decoding site maturation on the small ribosomal subunit. Sci Adv, 7, 2021
5QUE	HumRadA1.2 soaked with napht-2,3-diol for 10 minutes at 20 mM 分子名称: PHOSPHATE ION, RadA, naphthalene-2,3-diol 著者 Marsh, M, Hyvonen, M. 登録日 2020-01-27 公開日 2021-03-03 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (1.3 Å) 主引用文献 Optimisation of crystal forms for structure-guided drug discovery To be published
5QUH	HumRadA1.2 soaked with napht-2,3-diol overnight at 2 mM 分子名称: PHOSPHATE ION, RadA, naphthalene-2,3-diol 著者 Marsh, M, Hyvonen, M. 登録日 2020-01-27 公開日 2021-03-03 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (1.38 Å) 主引用文献 Optimisation of crystal forms for structure-guided drug discovery To be published
5QUF	HumRadA1.2 soaked with napht-2,3-diol overnight at 20 mM 分子名称: PHOSPHATE ION, RadA, naphthalene-2,3-diol 著者 Marsh, M, Hyvonen, M. 登録日 2020-01-27 公開日 2021-03-03 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (1.35 Å) 主引用文献 Optimisation of crystal forms for structure-guided drug discovery To be published
5QUD	HumRadA1.2 soaked with napht-2,3-diol for 5 minutes at 20 mM 分子名称: PHOSPHATE ION, RadA, naphthalene-2,3-diol 著者 Marsh, M, Hyvonen, M. 登録日 2020-01-27 公開日 2021-03-03 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (1.3 Å) 主引用文献 Optimisation of crystal forms for structure-guided drug discovery To be published
5QUB	HumRadA1.2 soaked with napht-2,3-diol for 30 seconds at 20 mM 分子名称: PHOSPHATE ION, RadA, naphthalene-2,3-diol 著者 Marsh, M, Hyvonen, M. 登録日 2020-01-27 公開日 2021-03-03 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (1.35 Å) 主引用文献 Optimisation of crystal forms for structure-guided drug discovery To be published
5QUG	HumRadA1.2 soaked with napht-2,3-diol overnight at 1 mM 分子名称: PHOSPHATE ION, RadA, naphthalene-2,3-diol 著者 Marsh, M, Hyvonen, M. 登録日 2020-01-27 公開日 2021-03-03 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (1.48 Å) 主引用文献 Optimisation of crystal forms for structure-guided drug discovery To be published
5QUO	HumRadA1 soaked with 0.2 mM indazole in 10% DMSO 分子名称: PHOSPHATE ION, RadA 著者 Marsh, M, Hyvonen, M. 登録日 2020-01-27 公開日 2021-03-03 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (1.342 Å) 主引用文献 Optimisation of crystal forms for structure-guided drug discovery To be published
5QUC	HumRadA1.2 soaked with napht-2,3-diol for 60 seconds at 20 mM 分子名称: PHOSPHATE ION, RadA, naphthalene-2,3-diol 著者 Marsh, M, Hyvonen, M. 登録日 2020-01-27 公開日 2021-03-03 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (1.43 Å) 主引用文献 Optimisation of crystal forms for structure-guided drug discovery To be published
5QUI	HumRadA1.2 soaked with napht-2,3-diol overnight at 5 mM 分子名称: PHOSPHATE ION, RadA, naphthalene-2,3-diol 著者 Marsh, M, Hyvonen, M. 登録日 2020-01-27 公開日 2021-03-03 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 Optimisation of crystal forms for structure-guided drug discovery To be published

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