PDB: 66324 件ウェブページステータス検索Chemie searchBIRD

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4GEO	P38a MAP kinase DEF-pocket penta mutant (M194A, L195A, H228A, I229A, Y258A) 分子名称: Mitogen-activated protein kinase 14, octyl beta-D-glucopyranoside 著者 Livnah, O, Tzarum, N. 登録日 2012-08-02 公開日 2013-05-22 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.66 Å) 主引用文献 P38a MAP kinase DEF-pocket penta mutant (M194A, L195A, H228A, I229A, Y258A) To be Published
5LRC	Crystal structure of Glycogen Phosphorylase in complex with KS114 分子名称: (1S)-1,5-anhydro-1-(5-phenyl-4H-1,2,4-triazol-3-yl)-D-glucitol, Glycogen phosphorylase, muscle form, ... 著者 Kantsadi, A.L, Stravodimos, G.A, Chatzileontiadou, D.S.M, Leonidas, D.D. 登録日 2016-08-18 公開日 2017-06-14 最終更新日 2020-08-05 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 van der Waals interactions govern C-beta-d-glucopyranosyl triazoles' nM inhibitory potency in human liver glycogen phosphorylase. J. Struct. Biol., 199, 2017
3D83	Crystal structure of P38 kinase in complex with a biphenyl amide inhibitor 分子名称: GLYCEROL, Mitogen-activated protein kinase 14, N-{4'-[(cyclopropylmethyl)carbamoyl]-6-methylbiphenyl-3-yl}-2-morpholin-4-ylpyridine-4-carboxamide 著者 Somers, D.O. 登録日 2008-05-22 公開日 2008-07-22 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Biphenyl amide p38 kinase inhibitors 4: DFG-in and DFG-out binding modes. Bioorg.Med.Chem.Lett., 18, 2008
7B24	DtxR-like iron-dependent regulator IdeR (P39G variant) complexed with cobalt and its consensus DNA-binding sequence 分子名称: COBALT (II) ION, DtxR family iron (Metal) dependent repressor, consensus DNA-binding sequence 著者 Maurer, D, Marcos-Torres, F.J, Griese, J.J. 登録日 2020-11-26 公開日 2021-03-03 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 The bacterial iron sensor IdeR recognizes its DNA targets by indirect readout. Nucleic Acids Res., 49, 2021
7B1Y	DtxR-like iron-dependent regulator IdeR complexed with cobalt and its consensus DNA-binding sequence 分子名称: COBALT (II) ION, DtxR family iron (Metal) dependent repressor, consensus DNA-binding sequence 著者 Maurer, D, Marcos-Torres, F.J, Griese, J.J. 登録日 2020-11-25 公開日 2021-03-03 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.12 Å) 主引用文献 The bacterial iron sensor IdeR recognizes its DNA targets by indirect readout. Nucleic Acids Res., 49, 2021
7B23	DtxR-like iron-dependent regulator IdeR complexed with cobalt and the SACE_2689 promoter DNA-binding sequence 分子名称: COBALT (II) ION, DtxR family iron (Metal) dependent repressor, SACE_2689 promoter DNA-binding sequence 著者 Maurer, D, Marcos-Torres, F.J, Griese, J.J. 登録日 2020-11-26 公開日 2021-03-03 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.15 Å) 主引用文献 The bacterial iron sensor IdeR recognizes its DNA targets by indirect readout. Nucleic Acids Res., 49, 2021
7B20	DtxR-like iron-dependent regulator IdeR complexed with iron and its consensus DNA-binding sequence 分子名称: DtxR family iron (Metal) dependent repressor, FE (II) ION, consensus DNA-binding sequence 著者 Maurer, D, Marcos-Torres, F.J, Griese, J.J. 登録日 2020-11-25 公開日 2021-03-03 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.18 Å) 主引用文献 The bacterial iron sensor IdeR recognizes its DNA targets by indirect readout. Nucleic Acids Res., 49, 2021
7B25	DtxR-like iron-dependent regulator IdeR (Q43A variant) complexed with cobalt and its consensus DNA-binding sequence 分子名称: COBALT (II) ION, DtxR family iron (Metal) dependent repressor, consensus DNA-binding sequence 著者 Maurer, D, Marcos-Torres, F.J, Griese, J.J. 登録日 2020-11-26 公開日 2021-03-03 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.34 Å) 主引用文献 The bacterial iron sensor IdeR recognizes its DNA targets by indirect readout. Nucleic Acids Res., 49, 2021
3DFC	Crystal structure of a glycine-rich loop mutant of the death associated protein kinase catalytic domain with AMPPNP 分子名称: Death-associated protein kinase 1, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER 著者 McNamara, L.K, Schavocky, J.P, Watterson, D.M, Brunzelle, J.S. 登録日 2008-06-11 公開日 2009-05-26 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 High resolution crystal structures of the death associated protein kinase catalytic domain with a key point mutation in the glycine-rich loop To be Published
5MXW	Crystal structure of yellow lupin LLPR-10.2B protein in complex with melatonin and trans-zeatin. 分子名称: (2E)-2-methyl-4-(9H-purin-6-ylamino)but-2-en-1-ol, Class 10 plant pathogenesis-related protein, N-[2-(5-methoxy-1H-indol-3-yl)ethyl]acetamide, ... 著者 Sliwiak, J, Sikorski, M, Jaskolski, M. 登録日 2017-01-25 公開日 2018-04-18 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.57 Å) 主引用文献 PR-10 proteins as potential mediators of melatonin-cytokinin cross-talk in plants: crystallographic studies of LlPR-10.2B isoform from yellow lupine. FEBS J., 285, 2018
5N04	X-ray crystal structure of an LPMO 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Auxiliary activity 9, CHLORIDE ION, ... 著者 Frandsen, K.E.H, Poulsen, J.-C.N, Lo Leggio, L. 登録日 2017-02-02 公開日 2017-03-29 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.76 Å) 主引用文献 Unliganded and substrate bound structures of the cellooligosaccharide active lytic polysaccharide monooxygenase LsAA9A at low pH. Carbohydr. Res., 448, 2017
7BBN	Crystal structure of an ancient sequence-reconstructed Elongation Factor Tu (node 317) 分子名称: Elongation Factor Tu, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION 著者 Majumdar, S, Bergfors, T, Sanyal, S. 登録日 2020-12-18 公開日 2022-01-19 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.68 Å) 主引用文献 Crystal structure of an ancient sequence-reconstructed Elongation factor Tu (node 317) To be published
7BN3	Crystal structure of C-terminal domain of PABPC1 in complex with Nucleoprotein from Human Coronavirus 229E 分子名称: GLYCEROL, Isoform 2 of Polyadenylate-binding protein 1, Nucleoprotein from Human Coronavirus 229E, ... 著者 Badgujar, D.C, Dobritzsch, D. 登録日 2021-01-21 公開日 2022-03-02 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.93 Å) 主引用文献 Large-scale phage-based screening reveals extensive pan-viral mimicry of host short linear motifs Nat Commun, 14, 2023
7BFC	Circular permutant of ribosomal protein S6, P54-55 truncated, 分子名称: 30S ribosomal protein S6,30S ribosomal protein S6 著者 Wang, H, Logan, D.T, Oliveberg, M. 登録日 2021-01-02 公開日 2022-07-13 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.13 Å) 主引用文献 Circular permutant of ribosomal protein S6 To Be Published
7BFD	Circular permutant of ribosomal protein S6, P54-55 truncated, Y4A mutant. 分子名称: 30S ribosomal protein S6,30S ribosomal protein S6 著者 Wang, H, Logan, D.T, Oliveberg, M. 登録日 2021-01-02 公開日 2022-07-13 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.57 Å) 主引用文献 Circular permutant of ribosomal protein S6 To Be Published
5LK6	Crystal structure of a lipase carboxylesterase from Sulfolobus islandicus 分子名称: Alpha/beta hydrolase fold-3 domain protein, SULFATE ION 著者 Schwarz-Linnet, T, Teilum, K, Olsen, J.G. 登録日 2016-07-21 公開日 2017-08-02 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 EstA from Sufolobus islandicus is stabilized by mono-methylation of lysine residues To Be Published
8HLK	Structure of McyB-C1A1 complexed with L-Leu and AMP 分子名称: ADENOSINE MONOPHOSPHATE, LEUCINE, Microcystin synthetase B (Fragment) 著者 Peng, Y.J. 登録日 2022-11-30 公開日 2023-12-13 最終更新日 2024-07-03 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Modular catalytic activity of nonribosomal peptide synthetases depends on the dynamic interaction between adenylation and condensation domains. Structure, 32, 2024
5LRF	Crystal structure of Glycogen Phosphorylase b in complex with KS389 分子名称: (2~{R},3~{S},4~{R},5~{R},6~{S})-2-(hydroxymethyl)-6-(3-naphthalen-2-yl-1~{H}-1,2,4-triazol-5-yl)oxane-3,4,5-triol, DIMETHYL SULFOXIDE, Glycogen phosphorylase, ... 著者 Kantsadi, A.L, Leonidas, D.D. 登録日 2016-08-18 公開日 2017-06-14 最終更新日 2019-02-20 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 van der Waals interactions govern C-beta-d-glucopyranosyl triazoles' nM inhibitory potency in human liver glycogen phosphorylase. J. Struct. Biol., 199, 2017
5LRE	Crystal structure of Glycogen Phosphorylase b in complex with KS382 分子名称: (2~{R},3~{S},4~{R},5~{R},6~{S})-2-(hydroxymethyl)-6-(3-naphthalen-2-yl-1~{H}-1,2,4-triazol-5-yl)oxane-3,4,5-triol, DIMETHYL SULFOXIDE, Glycogen phosphorylase, ... 著者 Kantsadi, A.L, Stravodimos, G.A, Kyriakis, E, Chatzileontiadou, D.S.M, Leonidas, D.D. 登録日 2016-08-18 公開日 2017-05-31 最終更新日 2018-01-17 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Synthetic, enzyme kinetic, and protein crystallographic studies of C-beta-d-glucopyranosyl pyrroles and imidazoles reveal and explain low nanomolar inhibition of human liver glycogen phosphorylase. Eur J Med Chem, 123, 2016
5NNS	Crystal structure of HiLPMO9B 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, ACRYLIC ACID, COPPER (II) ION, ... 著者 Dimarogona, M, Sandgren, M. 登録日 2017-04-10 公開日 2018-05-16 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Structural and molecular dynamics studies of a C1-oxidizing lytic polysaccharide monooxygenase from Heterobasidion irregulare reveal amino acids important for substrate recognition. FEBS J., 285, 2018
5LRD	Crystal structure of Glycogen Phosphorylase b in complex with KS242 分子名称: (2~{R},3~{S},4~{R},5~{R},6~{S})-2-(hydroxymethyl)-6-[5-(4-methylphenyl)-4~{H}-1,2,4-triazol-3-yl]oxane-3,4,5-triol, DIMETHYL SULFOXIDE, Glycogen phosphorylase, ... 著者 Kantsadi, A.L, Leonidas, D.D. 登録日 2016-08-18 公開日 2017-06-14 最終更新日 2017-06-28 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 van der Waals interactions govern C-beta-d-glucopyranosyl triazoles' nM inhibitory potency in human liver glycogen phosphorylase. J. Struct. Biol., 199, 2017
6ZRB	Crystal structure of SMYD3 conjugate with piperidine-based covalent inhibitor EM127 分子名称: ACETATE ION, Histone-lysine N-methyltransferase SMYD3, N-[1-(2-Chloroacetyl)piperidin-4-yl]-5-cyclopropyl-1,2-oxazole-3-carboxamide, ... 著者 Talibov, V.O, Eriksson, D. 登録日 2020-07-13 公開日 2022-07-27 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.55 Å) 主引用文献 Discovery of the 4-aminopiperidine-based compound EM127 for the site-specific covalent inhibition of SMYD3 Eur.J.Med.Chem., 2022
7A10	LppS with covalent adduct derived from 1g 分子名称: 4-methoxycyclohexa-2,5-diene-1-thione, L,D-transpeptidase 2 著者 Schnell, R, Steiner, E.M. 登録日 2020-08-11 公開日 2021-04-21 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 N-Thio-beta-lactams targeting L,D-transpeptidase-2, with activity against drug-resistant strains of Mycobacterium tuberculosis. Cell Chem Biol, 28, 2021
7A1E	LppS with covalent adduct derived from 1c 分子名称: ACETATE ION, L,D-transpeptidase 2, phenylmethanethiol 著者 Schnell, R, Steiner, E.M. 登録日 2020-08-12 公開日 2021-04-21 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.77 Å) 主引用文献 N-Thio-beta-lactams targeting L,D-transpeptidase-2, with activity against drug-resistant strains of Mycobacterium tuberculosis. Cell Chem Biol, 28, 2021
7A0Z	LppS with covalent adduct derived from 1b 分子名称: L,D-transpeptidase 2, TRIS(HYDROXYETHYL)AMINOMETHANE, benzenethiol 著者 Schnell, R, Steiner, E.M. 登録日 2020-08-11 公開日 2021-04-21 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.45 Å) 主引用文献 N-Thio-beta-lactams targeting L,D-transpeptidase-2, with activity against drug-resistant strains of Mycobacterium tuberculosis. Cell Chem Biol, 28, 2021

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