PDB: 37722 件ウェブページステータス検索Chemie searchBIRD

---

4ZS3	Structural complex of 5-aminofluorescein bound to the FTO protein 分子名称: 2-OXOGLUTARIC ACID, 5-amino-2-(6-hydroxy-3-oxo-3H-xanthen-9-yl)benzoic acid, Alpha-ketoglutarate-dependent dioxygenase FTO, ... 著者 Wang, T, Hong, T, Huang, Y, Yang, C.G, Zhou, X. 登録日 2015-05-13 公開日 2015-11-04 最終更新日 2024-11-06 実験手法 X-RAY DIFFRACTION (2.45 Å) 主引用文献 Fluorescein Derivatives as Bifunctional Molecules for the Simultaneous Inhibiting and Labeling of FTO Protein J.Am.Chem.Soc., 137, 2015
3RJG	Binary complex of DNA Polymerase Beta with a gapped DNA containing 8odG:dA base-pair at primer Terminus 分子名称: DNA (5'-D(*CP*CP*GP*AP*CP*GP*(8OG)P*CP*GP*CP*AP*TP*CP*AP*GP*C)-3'), DNA (5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*A)-3'), DNA (5'-D(P*GP*TP*CP*GP*G)-3'), ... 著者 Batra, V.K, Beard, W.A, Wilson, S.H. 登録日 2011-04-15 公開日 2012-01-18 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Binary complex crystal structure of DNA polymerase beta reveals multiple conformations of the templating 8-oxoguanine lesion Proc.Natl.Acad.Sci.USA, 109, 2012
8CZH	Human BAK in complex with the dM2 peptide 分子名称: Bcl-2 homologous antagonist/killer, DM2 peptide 著者 Aguilar, F, Keating, A.E. 登録日 2022-05-24 公開日 2023-01-11 最終更新日 2024-10-09 実験手法 X-RAY DIFFRACTION (1.3 Å) 主引用文献 Peptides from human BNIP5 and PXT1 and non-native binders of pro-apoptotic BAK can directly activate or inhibit BAK-mediated membrane permeabilization. Structure, 31, 2023
5A52	The crystal structure of Arabidopsis thaliana CAR1 in complex with one calcium ion 分子名称: CALCIUM ION, CALCIUM-DEPENDENT LIPID-BINDING DOMAIN-CONTAINING PROTEIN, GLYCEROL, ... 著者 Fernandez, D, Marquez, J.A. 登録日 2015-06-16 公開日 2016-03-02 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 Calcium-Dependent Oligomerization of Car Proteins at Cell Membrane Modulates Aba Signaling. Proc.Natl.Acad.Sci.USA, 113, 2016
8WXQ	Structure of WDR5 in complex with WIN motif containing MBD3C 分子名称: GLY-ALA-ALA-ARG-CYS-ARG-VAL-PHE-SER-PRO, WD repeat-containing protein 5 著者 Xu, L, Yang, Y. 登録日 2023-10-30 公開日 2024-06-26 最終更新日 2024-07-17 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Structural studies of WDR5 in complex with MBD3C WIN motif reveal a unique binding mode. J.Biol.Chem., 300, 2024
8CZF	Human BAK in complex with the dF2 peptide 分子名称: Bcl-2 homologous antagonist/killer, DF2 peptide 著者 Aguilar, F, Keating, A.E. 登録日 2022-05-24 公開日 2023-01-11 最終更新日 2024-10-23 実験手法 X-RAY DIFFRACTION (1.3 Å) 主引用文献 Peptides from human BNIP5 and PXT1 and non-native binders of pro-apoptotic BAK can directly activate or inhibit BAK-mediated membrane permeabilization. Structure, 31, 2023
8D4U	Crystal Structure of Neutrophil Elastase Inhibited by Eap2 from S. aureus 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Extracellular Adherence Protein, ... 著者 Gido, C.D, Herdendorf, T.J, Geisbrecht, B.V. 登録日 2022-06-02 公開日 2022-12-21 最終更新日 2024-11-13 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Characterization of two distinct neutrophil serine protease-binding modes within a Staphylococcus aureus innate immune evasion protein family. J.Biol.Chem., 299, 2023
7L92	C1B domain of Protein kinase C in complex with diacylglycerol and dodecyl 2-(trimethylammonio)ethyl phosphate 分子名称: DIACYL GLYCEROL, ETHANOL, Protein kinase C delta type, ... 著者 Katti, S.S, Krieger, I.V. 登録日 2021-01-01 公開日 2022-05-04 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Structural anatomy of Protein Kinase C C1 domain interactions with diacylglycerol and other agonists. Nat Commun, 13, 2022
4MDD	Crystal Structure of the Glucocorticoid Receptor Bound to a Non-steroidal Antagonist Reveals Repositioning and Partial Disordering of Activation Function Helix 12 分子名称: Glucocorticoid receptor, N-[2-{[benzyl(methyl)amino]methyl}-3-(4-fluoro-2-methoxyphenyl)-5-(propan-2-yl)-1H-indol-7-yl]methanesulfonamide, Nuclear receptor corepressor 1 著者 Coghlan, M.J, Luz, J.G. 登録日 2013-08-22 公開日 2014-12-03 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Crystal Structure of the Glucocorticoid Receptor Bound to a Non-steroidal Antagonist Reveals Repositioning and Partial Disordering of Activation Function Helix 12 To be Published
7LEO	C1B domain of Protein kinase C in complex with diacylglycerol-lactone (AJH-836) and 1,2-diheptanoyl-sn-glycero-3-phosphocholine 分子名称: (4S,7R)-7-(heptanoyloxy)-4-hydroxy-N,N,N-trimethyl-10-oxo-3,5,9-trioxa-4-phosphahexadecan-1-aminium 4-oxide, Protein kinase C delta type, ZINC ION, ... 著者 Katti, S.S, Krieger, I. 登録日 2021-01-14 公開日 2022-05-04 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 Structural anatomy of Protein Kinase C C1 domain interactions with diacylglycerol and other agonists. Nat Commun, 13, 2022
7LCB	C1B domain of Protein kinase C in complex with prostratin and phosphatidylcholine 分子名称: (4S,7R)-7-(heptanoyloxy)-4-hydroxy-N,N,N-trimethyl-10-oxo-3,5,9-trioxa-4-phosphahexadecan-1-aminium 4-oxide, Protein kinase C delta type, ZINC ION, ... 著者 Katti, S.S, Krieger, I.V. 登録日 2021-01-10 公開日 2022-05-04 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Structural anatomy of Protein Kinase C C1 domain interactions with diacylglycerol and other agonists. Nat Commun, 13, 2022
1YSM	NMR Structure of N-terminal domain (Residues 1-77) of Siah-Interacting Protein. 分子名称: Calcyclin-binding protein 著者 Bhattacharya, S, Lee, Y.T, Michowski, W, Jastrzebska, B, Filipek, A, Kuznicki, J, Chazin, W.J. 登録日 2005-02-08 公開日 2005-07-26 最終更新日 2024-05-22 実験手法 SOLUTION NMR 主引用文献 The Modular Structure of SIP Facilitates Its Role in Stabilizing Multiprotein Assemblies. Biochemistry, 44, 2005
7LF3	C1B domain of Protein kinase C in complex with diacylglycerol-lactone AJH-836 分子名称: (4S,7R)-7-(heptanoyloxy)-4-hydroxy-N,N,N-trimethyl-10-oxo-3,5,9-trioxa-4-phosphahexadecan-1-aminium 4-oxide, Protein kinase C delta type, ZINC ION, ... 著者 Katti, S.S, Krieger, I.V. 登録日 2021-01-15 公開日 2022-05-04 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.13 Å) 主引用文献 Structural anatomy of Protein Kinase C C1 domain interactions with diacylglycerol and other agonists. Nat Commun, 13, 2022
3RGE	Crystal structure of the W5H mutant of human carbonic anhydrase II 分子名称: Carbonic anhydrase 2, ZINC ION 著者 Domsic, J.F, Robbins, A.H, McKenna, R. 登録日 2011-04-08 公開日 2012-02-22 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.096 Å) 主引用文献 Structure and catalysis by carbonic anhydrase II: role of active-site tryptophan 5. Arch.Biochem.Biophys., 516, 2011
4ZS2	Structural complex of FTO/fluorescein 分子名称: 2-(6-HYDROXY-3-OXO-3H-XANTHEN-9-YL)-BENZOIC ACID, 2-OXOGLUTARIC ACID, Alpha-ketoglutarate-dependent dioxygenase FTO, ... 著者 Wang, T, Hong, T, Huang, Y, Yang, C.G, Zhou, X. 登録日 2015-05-13 公開日 2015-11-04 最終更新日 2024-10-30 実験手法 X-RAY DIFFRACTION (2.16 Å) 主引用文献 Fluorescein Derivatives as Bifunctional Molecules for the Simultaneous Inhibiting and Labeling of FTO Protein J.Am.Chem.Soc., 137, 2015
8CZG	Human BAK in complex with the dF3 peptide 分子名称: Bcl-2 homologous antagonist/killer, dF3 peptide 著者 Aguilar, F, Keating, A.E. 登録日 2022-05-24 公開日 2023-01-11 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.99 Å) 主引用文献 Peptides from human BNIP5 and PXT1 and non-native binders of pro-apoptotic BAK can directly activate or inhibit BAK-mediated membrane permeabilization. Structure, 31, 2023
8WXU	Structure of WDR5 in complex with WIN motif containing MBD3C C44S/R45E/V46G 分子名称: MBD3C, WD repeat-containing protein 5 著者 Xu, L, Yang, Y. 登録日 2023-10-30 公開日 2024-06-26 最終更新日 2024-07-17 実験手法 X-RAY DIFFRACTION (2.37 Å) 主引用文献 Structural studies of WDR5 in complex with MBD3C WIN motif reveal a unique binding mode. J.Biol.Chem., 300, 2024
4HIR	SOLUTION STRUCTURE OF RECOMBINANT HIRUDIN AND THE LYS-47 (RIGHT ARROW) GLU MUTANT. A NUCLEAR MAGNETIC RESONANCE AND HYBRID DISTANCE GEOMETRY-DYNAMICAL SIMULATED ANNEALING STUDY 分子名称: HIRUDIN VARIANT-1 著者 Clore, G.M, Gronenborn, A.M. 登録日 1988-12-19 公開日 1990-01-15 最終更新日 2024-11-06 実験手法 SOLUTION NMR 主引用文献 Solution structure of recombinant hirudin and the Lys-47----Glu mutant: a nuclear magnetic resonance and hybrid distance geometry-dynamical simulated annealing study. Biochemistry, 28, 1989
8D4Q	Crystal Structure of Neutrophil Elastase Inhibited by Eap1 from S. aureus 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Extracellular Adherence Protein, Neutrophil elastase 著者 Gido, C.D, Herdendorf, T.J, Geisbrecht, B.V. 登録日 2022-06-02 公開日 2022-12-21 最終更新日 2024-10-23 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Characterization of two distinct neutrophil serine protease-binding modes within a Staphylococcus aureus innate immune evasion protein family. J.Biol.Chem., 299, 2023
6AE8	Structure insight into histone chaperone Chz1-mediated H2A.Z recognition and replacement 分子名称: BICINE, Histone H2A.Z-specific chaperone CHZ1, Histone H2B.1,Histone H2A.Z 著者 Wang, Y.Y, Shan, S, Zhou, Z. 登録日 2018-08-03 公開日 2019-04-17 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 Structural insights into histone chaperone Chz1-mediated H2A.Z recognition and histone replacement. Plos Biol., 17, 2019
5X8A	Crystal structure of ATP bound thymidylate kinase from thermus thermophilus HB8 分子名称: ADENOSINE-5'-TRIPHOSPHATE, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ... 著者 Chaudhary, S.K, Jeyakanthan, J, Sekar, K. 登録日 2017-03-01 公開日 2018-03-14 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.51 Å) 主引用文献 Structural and functional roles of dynamically correlated residues in thymidylate kinase. Acta Crystallogr D Struct Biol, 74, 2018
4Q6F	Crystal structure of human BAZ2A PHD zinc finger in complex with unmodified H3K4 histone peptide 分子名称: 1,2-ETHANEDIOL, Bromodomain adjacent to zinc finger domain protein 2A, ZINC ION, ... 著者 Tallant, C, Overvoorde, L, Krojer, T, Filippakopoulos, P, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Ciulli, A, Knapp, S, Structural Genomics Consortium (SGC) 登録日 2014-04-22 公開日 2014-05-21 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.91 Å) 主引用文献 Molecular basis of histone tail recognition by human TIP5 PHD finger and bromodomain of the chromatin remodeling complex NoRC. Structure, 23, 2015
4M6T	Structure of human Paf1 and Leo1 complex 分子名称: RNA polymerase II-associated factor 1 homolog, Linker, RNA polymerase-associated protein LEO1, ... 著者 Shen, Y, Qin, X. 登録日 2013-08-11 公開日 2013-10-02 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (2.498 Å) 主引用文献 Structural insights into Paf1 complex assembly and histone binding Nucleic Acids Res., 41, 2013
4M74	Mutant structure of methyltransferase from Streptomyces hygroscopicus 分子名称: (2R)-2-hydroxy-3-phenylpropanoic acid, (2S,3R)-2,3-dihydroxy-3-phenylpropanoic acid, CALCIUM ION, ... 著者 Liu, Y.C, Zou, X.W, Chan, H.C, Huang, C.J, Li, T.L. 登録日 2013-08-12 公開日 2014-06-25 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Structure and mechanism of a nonhaem-iron SAM-dependent C-methyltransferase and its engineering to a hydratase and an O-methyltransferase Acta Crystallogr.,Sect.D, 70, 2014
4HKP	Crystal structure of human orotidine 5'-monophosphate decarboxylase complexed with CMP-N3-oxide 分子名称: 5-hydroxycytidine 5'-(dihydrogen phosphate), GLYCEROL, N-hydroxycytidine 5'-(dihydrogen phosphate), ... 著者 To, T.K, Kotra, L.P, Pai, E.F. 登録日 2012-10-15 公開日 2012-11-14 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Novel cytidine-based orotidine-5'-monophosphate decarboxylase inhibitors with an unusual twist. J.Med.Chem., 55, 2012

<967968969970971972973974975976977978979980981982>