8WXU

Structure of WDR5 in complex with WIN motif containing MBD3C C44S/R45E/V46G

Summary for 8WXU

• Entry DOI: 10.2210/pdb8wxu/pdb
• Descriptor: WD repeat-containing protein 5, MBD3C (3 entities in total)
• Functional Keywords: wdr5, mbd3c, win motif, chromatin, nuclear protein
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 2
• Total formula weight: 35810.52

Authors

Xu, L.,Yang, Y. (deposition date: 2023-10-30, release date: 2024-06-26, Last modification date: 2024-07-17)

• Primary citation: Yang, Y.,Xu, L.,Zhang, S.,Yao, L.,Ding, Y.,Li, W.,Chen, X.; Structural studies of WDR5 in complex with MBD3C WIN motif reveal a unique binding mode.; J.Biol.Chem., 300:107468-107468, 2024; PubMed: 38876301; DOI: 10.1016/j.jbc.2024.107468

Experimental method

X-RAY DIFFRACTION (2.37 Å)