6V90
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6v90 by Molmil](/molmil-images/mine/6v90) | |
6V9U
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6v9u by Molmil](/molmil-images/mine/6v9u) | Crystal structure of human TLR8 ectodomain bound to small molecule antagonist 14c | 分子名称: | 2-(3,4-dimethoxyphenyl)-5-(piperidin-4-yl)-3-(propan-2-yl)-1H-indole, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Critton, D.A. | 登録日 | 2019-12-16 | 公開日 | 2020-08-12 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.65 Å) | 主引用文献 | Discovery of Potent and Orally Bioavailable Small Molecule Antagonists of Toll-like Receptors 7/8/9 (TLR7/8/9). Acs Med.Chem.Lett., 11, 2020
|
|
7SML
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7sml by Molmil](/molmil-images/mine/7sml) | Crystal Structure of L-GALACTONO-1,4-LACTONE DEHYDROGENASE de Myrciaria dubia | 分子名称: | L-GALACTONO-1,4-LACTONE DEHYDROGENASE | 著者 | Santillan, J.A.V, Cabrejos, D.A.L, Pereira, H.M, Gomez, J.C.C, Garratt, R.C. | 登録日 | 2021-10-26 | 公開日 | 2022-11-02 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Structural insights into the Smirnoff-Wheeler pathway for vitamin C production in the Amazon fruit Camu-Camu. J.Exp.Bot., 2024
|
|
6P60
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6p60 by Molmil](/molmil-images/mine/6p60) | |
6YL4
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6yl4 by Molmil](/molmil-images/mine/6yl4) | Soluble epoxide hydrolase in complex with 3-((R)-3-(1-hydroxyureido)but-1-yn-1-yl)-N-((S)-3-phenyl-3-(4-trifluoromethoxy)phenyl)propyl)benzamide | 分子名称: | 3-[(3~{R})-3-[aminocarbonyl(oxidanyl)amino]but-1-ynyl]-~{N}-[(3~{S})-3-phenyl-3-[4-(trifluoromethyloxy)phenyl]propyl]benzamide, Bifunctional epoxide hydrolase 2 | 著者 | Kramer, J.S, Pogoryelov, D, Hiesinger, K, Proschak, E. | 登録日 | 2020-04-06 | 公開日 | 2020-10-21 | 最終更新日 | 2024-05-15 | 実験手法 | X-RAY DIFFRACTION (2.001 Å) | 主引用文献 | Design, Synthesis, and Structure-Activity Relationship Studies of Dual Inhibitors of Soluble Epoxide Hydrolase and 5-Lipoxygenase. J.Med.Chem., 63, 2020
|
|
6YPJ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6ypj by Molmil](/molmil-images/mine/6ypj) | |
6POP
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6pop by Molmil](/molmil-images/mine/6pop) | |
6PA3
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6pa3 by Molmil](/molmil-images/mine/6pa3) | |
7O15
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7o15 by Molmil](/molmil-images/mine/7o15) | ABC transporter NosDFY, nucleotide-free in lipid nanodisc, R-domain 2 | 分子名称: | MAGNESIUM ION, Probable ABC transporter ATP-binding protein NosF, Probable ABC transporter binding protein NosD, ... | 著者 | Mueller, C, Zhang, L, Lu, W, Einsle, O, Du, J. | 登録日 | 2021-03-28 | 公開日 | 2022-04-13 | 最終更新日 | 2024-07-10 | 実験手法 | ELECTRON MICROSCOPY | 主引用文献 | Molecular interplay of an assembly machinery for nitrous oxide reductase. Nature, 608, 2022
|
|
7O16
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7o16 by Molmil](/molmil-images/mine/7o16) | ABC transporter NosDFY, nucleotide-free in lipid nanodisc, R-domain 3 | 分子名称: | MAGNESIUM ION, Probable ABC transporter ATP-binding protein NosF, Probable ABC transporter binding protein NosD, ... | 著者 | Mueller, C, Zhang, L, Lu, W, Einsle, O, Du, J. | 登録日 | 2021-03-28 | 公開日 | 2022-04-13 | 最終更新日 | 2024-07-10 | 実験手法 | ELECTRON MICROSCOPY | 主引用文献 | Molecular interplay of an assembly machinery for nitrous oxide reductase. Nature, 608, 2022
|
|
7O12
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7o12 by Molmil](/molmil-images/mine/7o12) | ABC transporter NosDFY, AMPPNP-bound in GDN | 分子名称: | MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, Probable ABC transporter ATP-binding protein NosF, ... | 著者 | Mueller, C, Zhang, L, Lu, W, Einsle, O, Du, J. | 登録日 | 2021-03-28 | 公開日 | 2022-04-13 | 最終更新日 | 2024-07-10 | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | 主引用文献 | Molecular interplay of an assembly machinery for nitrous oxide reductase. Nature, 608, 2022
|
|
6YJ3
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6yj3 by Molmil](/molmil-images/mine/6yj3) | Metala-Carborane di-propyl-sulfonamide | 分子名称: | Carbonic anhydrase 2, Metala-Carborane di-propyl-sulfonamide, ZINC ION | 著者 | Brynda, J, Rezacova, P, Pospisilova, K, Kugler, M. | 登録日 | 2020-04-02 | 公開日 | 2020-09-09 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | 主引用文献 | Cobalt Bis(dicarbollide) Alkylsulfonamides: Potent and Highly Selective Inhibitors of Tumor Specific Carbonic Anhydrase IX. Chempluschem, 86, 2021
|
|
7O10
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7o10 by Molmil](/molmil-images/mine/7o10) | ABC transporter NosDFY, nucleotide-free in GDN, R-domain 2 | 分子名称: | MAGNESIUM ION, Probable ABC transporter ATP-binding protein NosF, Probable ABC transporter binding protein NosD, ... | 著者 | Mueller, C, Zhang, L, Lu, W, Einsle, O, Du, J. | 登録日 | 2021-03-28 | 公開日 | 2022-04-13 | 最終更新日 | 2024-07-10 | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | 主引用文献 | Molecular interplay of an assembly machinery for nitrous oxide reductase. Nature, 608, 2022
|
|
7O11
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7o11 by Molmil](/molmil-images/mine/7o11) | ABC transporter NosDFY, nucleotide-free in GDN, R-domain 1 | 分子名称: | MAGNESIUM ION, Probable ABC transporter ATP-binding protein NosF, Probable ABC transporter binding protein NosD, ... | 著者 | Mueller, C, Zhang, L, Lu, W, Einsle, O, Du, J. | 登録日 | 2021-03-28 | 公開日 | 2022-04-13 | 最終更新日 | 2024-07-10 | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | 主引用文献 | Molecular interplay of an assembly machinery for nitrous oxide reductase. Nature, 608, 2022
|
|
2MBM
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2mbm by Molmil](/molmil-images/mine/2mbm) | Solution NMR Structure of De novo designed Top7 Fold Protein Top7m13, Northeast Structural Genomics Consortium (NESG) Target OR33 | 分子名称: | Top7 Fold Protein Top7m13 | 著者 | Liu, G, Zanghellini, A.L, Chan, K, Xiao, R, Janjua, H, Kogan, S, Maglaqui, M, Ciccosanti, C, Acton, T.B, Kornhaber, G, Everett, J.K, Baker, D, Montelione, G.T, Northeast Structural Genomics Consortium (NESG) | 登録日 | 2013-08-02 | 公開日 | 2013-11-13 | 最終更新日 | 2023-06-14 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution NMR Structure of De novo designed Top7 Fold Protein Top7m13, Northeast Structural Genomics Consortium (NESG) Target OR33 To be Published
|
|
6Y14
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6y14 by Molmil](/molmil-images/mine/6y14) | |
6PA8
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6pa8 by Molmil](/molmil-images/mine/6pa8) | |
6PK6
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6pk6 by Molmil](/molmil-images/mine/6pk6) | Human PRPF4B bound to benzothiophene inhibitor 329 | 分子名称: | 4-(5-{[(2-aminophenyl)methyl]carbamoyl}thiophen-2-yl)-1-benzothiophene-2-carboxamide, SULFATE ION, Serine/threonine-protein kinase PRP4 homolog | 著者 | Godoi, P.H.C, Santiago, A.S, Fala, A.M, Ramos, P.Z, Sriranganadane, D, Mascarello, A, Segretti, N, Azevedo, H, Guimaraes, C.R.W, Arruda, P, Elkins, J.M, Counago, R.M, Structural Genomics Consortium (SGC) | 登録日 | 2019-06-28 | 公開日 | 2019-08-28 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | to be published To Be Published
|
|
6Y1S
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6y1s by Molmil](/molmil-images/mine/6y1s) | |
6P05
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6p05 by Molmil](/molmil-images/mine/6p05) | Bromodomain-containing protein 4 (BRD4) bromodomain 1 (BD1) complexed with compound 27 | 分子名称: | Bromodomain-containing protein 4, GLYCEROL, N-{1-[1,1-di(pyridin-2-yl)ethyl]-6-(1-methyl-7-oxo-6,7-dihydro-1H-pyrrolo[2,3-c]pyridin-3-yl)-1H-indol-4-yl}ethanesulfonamide | 著者 | Ratia, K.M, Xiong, R, Li, Y, Zhao, J, Gutgesell, L.M, Shen, Z, Dye, K, Dubrovyskyii, O, Zhao, H, Huang, F, Tonetti, D.A, Thatcher, G.R. | 登録日 | 2019-05-16 | 公開日 | 2020-05-20 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.54 Å) | 主引用文献 | Novel Pyrrolopyridone Bromodomain and Extra-Terminal Motif (BET) Inhibitors Effective in Endocrine-Resistant ER+ Breast Cancer with Acquired Resistance to Fulvestrant and Palbociclib. J.Med.Chem., 63, 2020
|
|
6PHV
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6phv by Molmil](/molmil-images/mine/6phv) | SpAga galactose product complex structure | 分子名称: | 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Alpha-galactosidase, ... | 著者 | Pluvinage, B, Boraston, A.B. | 登録日 | 2019-06-25 | 公開日 | 2019-10-02 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Molecular analysis of an enigmaticStreptococcus pneumoniaevirulence factor: The raffinose-family oligosaccharide utilization system. J.Biol.Chem., 294, 2019
|
|
7ODE
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7ode by Molmil](/molmil-images/mine/7ode) | |
6P1A
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6p1a by Molmil](/molmil-images/mine/6p1a) | |
6Y6R
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6y6r by Molmil](/molmil-images/mine/6y6r) | |
6Y99
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6y99 by Molmil](/molmil-images/mine/6y99) | hSTING mutant R232K in complex with 2',3'-cGAMP | 分子名称: | Stimulator of interferon genes protein, cGAMP | 著者 | Boura, E, Smola, M. | 登録日 | 2020-03-06 | 公開日 | 2021-03-31 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.984 Å) | 主引用文献 | Ligand Strain and Its Conformational Complexity Is a Major Factor in the Binding of Cyclic Dinucleotides to STING Protein. Angew.Chem.Int.Ed.Engl., 60, 2021
|
|