PDB: 47065 件ウェブページステータス検索Chemie searchBIRD

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4YDF	Crystal structure of compound 9 in complex with HTLV-1 Protease 分子名称: HTLV-1 Protease, N-benzyl-N-[(3S,4S)-4-{benzyl[(4-nitrophenyl)sulfonyl]amino}pyrrolidin-3-yl]-3-nitrobenzenesulfonamide, SULFATE ION 著者 Kuhnert, M, Blum, A, Steuber, H, Diederich, W.E. 登録日 2015-02-22 公開日 2016-02-03 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.804 Å) 主引用文献 Privileged Structures Meet Human T-Cell Leukemia Virus-1 (HTLV-1): C2-Symmetric 3,4-Disubstituted Pyrrolidines as Nonpeptidic HTLV-1 Protease Inhibitors. J.Med.Chem., 58, 2015
4YLC	Crystal Structure of Del-C4 mutant of hsp14.1 from Sulfolobus solfatataricus P2 分子名称: CHLORIDE ION, Heat shock protein Hsp20 著者 Liu, L, Chen, J.Y, Yun, C.H. 登録日 2015-03-05 公開日 2015-11-04 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 Active-State Structures of a Small Heat-Shock Protein Revealed a Molecular Switch for Chaperone Function Structure, 23, 2015
2MOQ	Solution Structure and Molecular determinants of Hemoglobin Binding of the first NEAT Domain of IsdB in Staphylococcus aureus 分子名称: Iron-regulated surface determinant protein B 著者 Fonner, B.A, Tripet, B.P, Eilers, B.J, Stanisich, J, Sullivan-Springhetti, R.K, Moore, R, Lui, M, Lei, B, Copie, V. 登録日 2014-04-29 公開日 2014-07-02 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 Solution Structure and Molecular Determinants of Hemoglobin Binding of the First NEAT Domain of IsdB in Staphylococcus aureus. Biochemistry, 53, 2014
5UIF	Crystal Structure of Native Ps01740 分子名称: Ps01740 著者 LeVieux, J, Baas, B.J, Zhang, Y.J, Whitman, C.P. 登録日 2017-01-13 公開日 2017-11-22 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.57 Å) 主引用文献 Kinetic and structural characterization of a cis-3-Chloroacrylic acid dehalogenase homologue in Pseudomonas sp. UW4: A potential step between subgroups in the tautomerase superfamily. Arch. Biochem. Biophys., 636, 2017
4YMK	Crystal Structure of Stearoyl-Coenzyme A Desaturase 1 分子名称: Acyl-CoA desaturase 1, STEAROYL-COENZYME A, ZINC ION, ... 著者 Bai, Y, McCoy, J.G, Rajashankar, K.R, Zhou, M. 登録日 2015-03-06 公開日 2015-06-24 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.605 Å) 主引用文献 X-ray structure of a mammalian stearoyl-CoA desaturase. Nature, 524, 2015
2MQP	Structural Investigation of hnRNP L bound to RNA 分子名称: Protein Hnrnpl, RNA (5'-R(*AP*CP*AP*CP*AP*C)-3') 著者 Blatter, M, Allain, F. 登録日 2014-06-24 公開日 2015-12-23 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 Structural Investigation of hnRNP L bound to RNA To be Published
2MU7	Shortening and modifying the 1513 MSP-1 peptide's alpha-helical region induces protection against malaria 分子名称: 1513 MSP-1 peptide 著者 Espejo, F, Bermudez, A, Torres, E, Urquiza, M, Rodriguez, R, Lopez, Y, Patarroyo, M. 登録日 2014-09-04 公開日 2014-11-12 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 Shortening and modifying the 1513 MSP-1 peptide's alpha-helical region induces protection against malaria. Biochem.Biophys.Res.Commun., 315, 2004
5UKW	Crystal structure of human Glucose 6-phosphate Dehydrogenase mutant (A277C) complexed with G6P 分子名称: 6-O-phosphono-beta-D-glucopyranose, GLYCEROL, Glucose-6-phosphate 1-dehydrogenase 著者 Ranzani, A.T, Cordeiro, A.T. 登録日 2017-01-23 公開日 2017-04-19 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.65 Å) 主引用文献 Mutations in the tetramer interface of human glucose-6-phosphate dehydrogenase reveals kinetic differences between oligomeric states. FEBS Lett., 591, 2017
5UJ9	Cryo-EM structure of bovine multidrug resistance protein 1 (MRP1) 分子名称: bovine multidrug resistance protein 1 (MRP1),Multidrug resistance-associated protein 1 著者 Johnson, Z.L, Chen, J. 登録日 2017-01-17 公開日 2017-02-22 最終更新日 2024-03-13 実験手法 ELECTRON MICROSCOPY (3.49 Å) 主引用文献 Structural Basis of Substrate Recognition by the Multidrug Resistance Protein MRP1. Cell, 168, 2017
4YO1	Structure of Legionella pneumophila DegQ (delta PDZ2 variant) 分子名称: CADMIUM ION, DegQ 著者 Wrase, R, Hilgenfeld, R, Hansen, G. 登録日 2015-03-11 公開日 2015-06-24 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Structures of DegQ from Legionella pneumophila Define Distinct ON and OFF States. J.Mol.Biol., 427, 2015
5ULX	Structure of human DNA polymerase iota bound to template 1-methyl-deoxyadenosine crystallized in the presence of dCTP 分子名称: CHLORIDE ION, DNA (5'-D(*AP*GP*GP*AP*CP*CP*(DOC))-3'), DNA (5'-D(P*(MA7)P*GP*GP*GP*TP*CP*CP*T)-3'), ... 著者 Jain, R, Aggarwal, A.K. 登録日 2017-01-25 公開日 2017-04-19 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.96 Å) 主引用文献 Mechanism of error-free DNA synthesis across N1-methyl-deoxyadenosine by human DNA polymerase-iota. Sci Rep, 7, 2017
2MWG	Full-Length Solution Structure Of YtvA, a LOV-Photoreceptor Protein and Regulator of Bacterial Stress Response 分子名称: Blue-light photoreceptor, FLAVIN MONONUCLEOTIDE 著者 Jurk, M, Bardiaux, B, Schmieder, P. 登録日 2014-11-07 公開日 2016-05-25 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 Solution Structure of YtvA from Bacillus subtilis Provides Insight into Activation Mechanism and Regulation of Bacterial Stress Response. To be Published
4YIH	Crystal structure of human cytosolic 5'(3')-deoxyribonucleotidase in complex with the inhibitor PB-PVU 分子名称: 1-{2-deoxy-3,5-O-[phenyl(phosphono)methylidene]-beta-D-threo-pentofuranosyl}-5-[(E)-2-phosphonoethenyl]pyrimidine-2,4(1H,3H)-dione, 5'(3')-deoxyribonucleotidase, cytosolic type, ... 著者 Pachl, P, Rezacova, P, Brynda, J. 登録日 2015-03-02 公開日 2015-09-09 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.82 Å) 主引用文献 Structure-based design of a bisphosphonate 5'(3')-deoxyribonucleotidase inhibitor Medchemcomm, 6, 2015
6BFZ	Crystal structure of enolase from E. coli with a mixture of apo form, substrate, and product form 分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 2-PHOSPHOGLYCERIC ACID, Enolase, ... 著者 Erlandsen, H, Wright, D, Krucinska, J. 登録日 2017-10-27 公開日 2018-10-31 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.21 Å) 主引用文献 Structural and Functional Studies of Bacterial Enolase, a Potential Target against Gram-Negative Pathogens. Biochemistry, 58, 2019
4YIR	Crystal structure of Rad4-Rad23 crosslinked to an undamaged DNA 分子名称: DNA (5'-D(*AP*TP*TP*GP*TP*AP*GP*CP*G*GP*GP*GP*AP*TP*GP*TP*CP*GP*AP*GP*TP*CP*A)-3'), DNA (5'-D(*TP*TP*GP*AP*CP*TP*CP*(G47)P*AP*CP*AP*TP*CP*CP*CP*CP*CP*GP*CP*TP*AP*CP*AP*A)-3'), DNA repair protein RAD4, ... 著者 Min, J.-H, Chen, X, Kim, Y. 登録日 2015-03-02 公開日 2015-03-11 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (3.0501 Å) 主引用文献 Kinetic gating mechanism of DNA damage recognition by Rad4/XPC. Nat Commun, 6, 2015
5UKP	Structure of unliganded anti-gp120 CD4bs antibody DH522.1 Fab 分子名称: DH522.1 Fab fragment heavy chain, DH522.1 Fab fragment light chain 著者 Nicely, N.I. 登録日 2017-01-23 公開日 2017-12-06 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Initiation of HIV neutralizing B cell lineages with sequential envelope immunizations. Nat Commun, 8, 2017
5UKN	Structure of unliganded anti-gp120 CD4bs antibody DH522UCA Fab 分子名称: CHLORIDE ION, DH522UCA Fab fragment heavy chain, DH522UCA Fab fragment light chain 著者 Nicely, N.I. 登録日 2017-01-23 公開日 2017-12-06 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Initiation of HIV neutralizing B cell lineages with sequential envelope immunizations. Nat Commun, 8, 2017
4YQE	Crystal structure of E. coli WrbA in complex with benzoquinone 分子名称: 1,4-benzoquinone, FLAVIN MONONUCLEOTIDE, NAD(P)H dehydrogenase (quinone) 著者 Degtjarik, O, Brynda, J, Ettrichova, O, Carey, J, Kuta Smatanova, I, Ettrich, R. 登録日 2015-03-13 公開日 2016-05-25 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.33 Å) 主引用文献 Quantum Calculations Indicate Effective Electron Transfer between FMN and Benzoquinone in a New Crystal Structure of Escherichia coli WrbA. J.Phys.Chem.B, 120, 2016
5V18	Structure of PHD2 in complex with 1,2,4-Triazolo-[1,5-a]pyridine 分子名称: 4-([1,2,4]triazolo[1,5-a]pyridin-5-yl)benzonitrile, Egl nine homolog 1, FE (II) ION, ... 著者 Skene, R.J. 登録日 2017-03-01 公開日 2017-06-21 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (2.15 Å) 主引用文献 1,2,4-Triazolo-[1,5-a]pyridine HIF Prolylhydroxylase Domain-1 (PHD-1) Inhibitors With a Novel Monodentate Binding Interaction. J. Med. Chem., 60, 2017
5UOB	Structure of human endothelial nitric oxide synthase heme domain in complex with (R)-3-[(2-amino-4-methylquinolin-7-yl)methoxy]-5-(2-(methylamino)propyl)benzonitrile 分子名称: 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 3-[(2-amino-4-methylquinolin-7-yl)methoxy]-5-[(2R)-2-(methylamino)propyl]benzonitrile, CHLORIDE ION, ... 著者 Chreifi, G, Li, H, Poulos, T.L. 登録日 2017-01-31 公開日 2017-05-03 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.292 Å) 主引用文献 Nitrile in the Hole: Discovery of a Small Auxiliary Pocket in Neuronal Nitric Oxide Synthase Leading to the Development of Potent and Selective 2-Aminoquinoline Inhibitors. J. Med. Chem., 60, 2017
2NBZ	Solution structure of the K domain of EMCV IRES 分子名称: IRES RNA 40-MER 著者 Imai, S, D'Souza, V, Wagner, G. 登録日 2016-03-16 公開日 2016-08-10 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 An accurately preorganized IRES RNA structure enables eIF4G capture for initiation of viral translation. Nat. Struct. Mol. Biol., 23, 2016
6B7A	Crystal structure of E.coli Phosphopantetheine Adenylyltransferase (PPAT/CoaD) in complex with 2-methyl-1H-benzo[d]imidazol-4-ol 分子名称: 2-methyl-1H-benzimidazol-7-ol, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ... 著者 Proudfoot, A.W, Bussiere, D, Lingel, A. 登録日 2017-10-03 公開日 2017-12-27 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.991 Å) 主引用文献 High-Confidence Protein-Ligand Complex Modeling by NMR-Guided Docking Enables Early Hit Optimization. J. Am. Chem. Soc., 139, 2017
4Y3S	Endothiapepsin in complex with fragment 266 分子名称: 6-(dimethylamino)pyridine-3-carboxylic acid, ACETATE ION, Endothiapepsin, ... 著者 Krimmer, S.G, Heine, A, Klebe, G. 登録日 2015-02-10 公開日 2016-02-17 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.1 Å) 主引用文献 Crystallographic Fragment Screening of an Entire Library To Be Published
4Y47	Endothiapepsin in complex with fragment 162 分子名称: 4-oxo-N-[(1S)-1-(pyridin-3-yl)ethyl]-4-(thiophen-2-yl)butanamide, ACETATE ION, Endothiapepsin, ... 著者 Krimmer, S.G, Krug, M, Uehlein, M, Heine, A, Klebe, G. 登録日 2015-02-10 公開日 2016-02-17 実験手法 X-RAY DIFFRACTION (1.19 Å) 主引用文献 Crystallographic Fragment Screening of an Entire Library To Be Published
2N7A	Solution structure of the human Siglec-8 lectin domain 分子名称: Sialic acid-binding Ig-like lectin 8 著者 Proepster, J.M, Yang, F, Rabbani, S, Ernst, B, Allain, F.H.-T, Schubert, M. 登録日 2015-09-07 公開日 2016-07-06 最終更新日 2023-06-14 実験手法 SOLUTION NMR 主引用文献 Structural basis for sulfation-dependent self-glycan recognition by the human immune-inhibitory receptor Siglec-8. Proc.Natl.Acad.Sci.USA, 113, 2016

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