2N7A
Solution structure of the human Siglec-8 lectin domain
Summary for 2N7A
Entry DOI | 10.2210/pdb2n7a/pdb |
Related | 2N7B |
NMR Information | BMRB: 25798 |
Descriptor | Sialic acid-binding Ig-like lectin 8 (1 entity in total) |
Functional Keywords | sialic acid-binding immunoglobulin-like lectin 8, siglec8, saf-2, i-type lectin, carbohydrate-binding receptor, structural protein |
Biological source | Homo sapiens (human) |
Cellular location | Membrane; Single-pass type I membrane protein: Q9NYZ4 |
Total number of polymer chains | 1 |
Total formula weight | 16665.46 |
Authors | Proepster, J.M.,Yang, F.,Rabbani, S.,Ernst, B.,Allain, F.H.-T.,Schubert, M. (deposition date: 2015-09-07, release date: 2016-07-06, Last modification date: 2023-06-14) |
Primary citation | Propster, J.M.,Yang, F.,Rabbani, S.,Ernst, B.,Allain, F.H.,Schubert, M. Structural basis for sulfation-dependent self-glycan recognition by the human immune-inhibitory receptor Siglec-8. Proc.Natl.Acad.Sci.USA, 113:E4170-E4179, 2016 Cited by PubMed: 27357658DOI: 10.1073/pnas.1602214113 PDB entries with the same primary citation |
Experimental method | SOLUTION NMR |
Structure validation
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