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2N7A

Solution structure of the human Siglec-8 lectin domain

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1ASialic acid-binding Ig-like lectin 8polymer14516665.51UniProt (Q9NYZ4)
Pfam (PF07686)
In PDB
Homo sapiens (human)Siglec-8, Sialoadhesin family member 2, SAF-2
Sequence modifications
A: 1 - 139 (UniProt: Q9NYZ4)
PDBExternal DatabaseDetails
Ser 26Cys 42engineered mutation
Gly 140-expression tag
Ser 141-expression tag
Leu 142-expression tag
Val 143-expression tag
Pro 144-expression tag
Arg 145-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight16665.5
All*Total formula weight16665.5
*Water molecules are not included.

223166

PDB entries from 2024-07-31

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