PDB: 42250 件ウェブページステータス検索Chemie searchBIRD

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3KX9	Engineering a closed form of the Archaeoglobus fulgidus ferritin by site directed mutagenesis 分子名称: Ferritin, GLYCEROL 著者 Johnson, E, Cascio, D, Sawaya, M.R. 登録日 2009-12-02 公開日 2010-12-15 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.101 Å) 主引用文献 The role of nonconserved residues of Archaeoglobus fulgidus ferritin on its unique structure and biophysical properties. J.Biol.Chem., 288, 2013
8DDJ	Open MscS in PC14.1 Nanodiscs 分子名称: Mechanosensitive channel MscS 著者 Reddy, B.G, Bavi, N, Perozo, E. 登録日 2022-06-18 公開日 2023-02-15 最終更新日 2025-05-21 実験手法 ELECTRON MICROSCOPY (3.1 Å) 主引用文献 State-specific morphological deformations of the lipid bilayer explain mechanosensitive gating of MscS ion channels. Elife, 12, 2023
9OMO	mGluR7 in native membrane vesicles 分子名称: Metabotropic glutamate receptor 7 著者 Mandala, V, Fu, Z, MacKinnon, R. 登録日 2025-05-14 公開日 2025-07-09 実験手法 ELECTRON MICROSCOPY (4.1 Å) 主引用文献 Molecular contacts in self-assembling clusters of membrane proteins. Proc.Natl.Acad.Sci.USA, 122, 2025
1R26	Crystal structure of thioredoxin from Trypanosoma brucei brucei 分子名称: Thioredoxin 著者 Friemann, R, Schmidt, H, Ramaswamy, S, Forstner, M, Krauth-Siegel, R.L, Eklund, H. 登録日 2003-09-26 公開日 2003-12-09 最終更新日 2024-11-06 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 Structure of thioredoxin from Trypanosoma brucei brucei FEBS Lett., 554, 2003
6RRG	Human Carbonic Anhydrase II in complex with fluorinated benzenesulfonamide 分子名称: (4-CARBOXYPHENYL)(CHLORO)MERCURY, 3,5-DIFLUOROBENZENESULFONAMIDE, Carbonic anhydrase 2, ... 著者 Gloeckner, S, Heine, A, Klebe, G. 登録日 2019-05-17 公開日 2020-04-15 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.127 Å) 主引用文献 The Influence of Varying Fluorination Patterns on the Thermodynamics and Kinetics of Benzenesulfonamide Binding to Human Carbonic Anhydrase II. Biomolecules, 10, 2020
9GJ4	Structure of the amyloid-forming peptide LYNleQNY 分子名称: Peptide LYNleQNY 著者 Durvanger, Z. 登録日 2024-08-21 公開日 2025-07-09 実験手法 X-RAY DIFFRACTION (1.55 Å) 主引用文献 Chemical Evolution of Early Macromolecules: From Prebiotic Oligopeptides to Self-Organizing Biosystems via Amyloid Formation. Chemistry, 31, 2025
9NIL	Structure of a Y1216F mutant of the acyltransferase domain of NcdE, a multi-domain NRPS protein from nocardichelin biosynthesis 分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, NcdE 著者 Fisk, M.B, Gulick, A.M, Barrera Ramirez, J. 登録日 2025-02-26 公開日 2025-07-09 実験手法 X-RAY DIFFRACTION (1.44 Å) 主引用文献 Identification and Characterization of the Biosynthesis of the Hybrid NRPS-NIS Siderophore Nocardichelin. Acs Chem.Biol., 20, 2025
6UOK	Y271G DNA polymerase beta substrate complex with templating cytosine and incoming r8-oxo-GTP 分子名称: 1,2-ETHANEDIOL, 8-OXO-GUANOSINE-5'-TRIPHOSPHATE, CHLORIDE ION, ... 著者 Smith, M.R, Freudenthal, B.D. 登録日 2019-10-15 公開日 2020-01-08 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.55 Å) 主引用文献 Molecular and structural characterization of oxidized ribonucleotide insertion into DNA by human DNA polymerase beta. J.Biol.Chem., 295, 2020
6RW1	Crystal structure of hCA II in complex with Urea, N-(1,3-dihydro-1-hydroxy-2,1-benzoxaborol-6-yl)-N'-(phenylmethyl)- 分子名称: 1-[7,7-bis(oxidanyl)-8-oxa-7-boranuidabicyclo[4.3.0]nona-1(6),2,4-trien-4-yl]-3-(phenylmethyl)thiourea, Carbonic anhydrase 2, ZINC ION 著者 Di Fiore, A, De Simone, G. 登録日 2019-06-03 公開日 2019-08-28 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Exploring benzoxaborole derivatives as carbonic anhydrase inhibitors: a structural and computational analysis reveals their conformational variability as a tool to increase enzyme selectivity. J Enzyme Inhib Med Chem, 34, 2019
6RS5	Human Carbonic Anhydrase II in complex with fluorinated benzenesulfonamide 分子名称: (4-CARBOXYPHENYL)(CHLORO)MERCURY, 2,3,5,6-tetrakis(fluoranyl)-4-methyl-benzenesulfonamide, Carbonic anhydrase 2, ... 著者 Gloeckner, S, Ngo, K, Heine, A, Klebe, G. 登録日 2019-05-21 公開日 2020-04-15 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.07 Å) 主引用文献 The Influence of Varying Fluorination Patterns on the Thermodynamics and Kinetics of Benzenesulfonamide Binding to Human Carbonic Anhydrase II. Biomolecules, 10, 2020
6UIQ	Crystal structure of wild-type human phosphoglucomutase 1 in complex with Glucose-6-Phosphate 分子名称: 6-O-phosphono-alpha-D-glucopyranose, MAGNESIUM ION, phosphoglucomutase-1 著者 Stiers, K.M, Beamer, L.J. 登録日 2019-10-01 公開日 2020-08-12 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 A Hotspot for Disease-Associated Variants of Human PGM1 Is Associated with Impaired Ligand Binding and Loop Dynamics. Structure, 26, 2018
9OMP	mGluR7 in native membrane vesicles 分子名称: Metabotropic glutamate receptor 7 著者 Mandala, V, Fu, Z, MacKinnon, R. 登録日 2025-05-14 公開日 2025-07-09 実験手法 ELECTRON MICROSCOPY (4.3 Å) 主引用文献 Molecular contacts in self-assembling clusters of membrane proteins. Proc.Natl.Acad.Sci.USA, 122, 2025
4EOZ	Crystal structure of the SPOP BTB domain complexed with the Cul3 N-terminal domain 分子名称: Cullin-3, Speckle-type POZ protein 著者 Prive, G.G, Errington, W.J. 登録日 2012-04-16 公開日 2012-05-30 最終更新日 2024-11-20 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Adaptor protein self-assembly drives the control of a cullin-RING ubiquitin ligase. Structure, 20, 2012
4ZO1	Crystal Structure of the T3-bound TR-beta Ligand-binding Domain in complex with RXR-alpha 分子名称: 3,5,3'TRIIODOTHYRONINE, Nuclear receptor coactivator 2, Retinoic acid receptor RXR-alpha, ... 著者 Bruning, J.B, Kojetin, D.J, Matta-Camacho, E, Hughes, T.S, Srinivasan, S, Nwachukwu, J.C, Cavett, V, Nowak, J, Chalmers, M.J, Marciano, D.P, Kamenecka, T.M, Rance, M, Shulman, A.I, Mangelsdorf, D.J, Griffin, P.R, Nettles, K.W. 登録日 2015-05-05 公開日 2015-09-02 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (3.221 Å) 主引用文献 Structural mechanism for signal transduction in RXR nuclear receptor heterodimers. Nat Commun, 6, 2015
6TVE	Unliganded human CD73 (5'-nucleotidase) in the open state 分子名称: 5'-nucleotidase, CALCIUM ION, DIMETHYL SULFOXIDE, ... 著者 Scaletti, E, Strater, N. 登録日 2020-01-09 公開日 2020-02-19 最終更新日 2024-10-09 実験手法 X-RAY DIFFRACTION (1.05 Å) 主引用文献 2-Substituted alpha , beta-Methylene-ADP Derivatives: Potent Competitive Ecto-5'-nucleotidase (CD73) Inhibitors with Variable Binding Modes. J.Med.Chem., 63, 2020
9FVK	Crystal structure of amyloidogenic light chain AL-55 in open conformation. 分子名称: 1,2-ETHANEDIOL, AL55, DI(HYDROXYETHYL)ETHER, ... 著者 Polsinelli, I, Puri, S, Broggini, L, Gadda, A, Petralia, U, Ricagno, S. 登録日 2024-06-27 公開日 2025-07-09 実験手法 X-RAY DIFFRACTION (2.64 Å) 主引用文献 To be published To Be Published
1GW6	STRUCTURE OF LEUKOTRIENE A4 HYDROLASE D375N MUTANT 分子名称: 2-(3-AMINO-2-HYDROXY-4-PHENYL-BUTYRYLAMINO)-4-METHYL-PENTANOIC ACID, ACETATE ION, IMIDAZOLE, ... 著者 Rudberg, P.C, Tholander, F, Thunnissen, M.M.G.M, Samuelsson, B, Haeggstrom, J.Z. 登録日 2002-03-07 公開日 2003-03-06 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Leukotriene A4 Hydrolase: Selective Abrogation of Leukotriene B4 Formation by Mutation of Aspartic Acid 375 Proc.Natl.Acad.Sci.USA, 99, 2002
3OYQ	Structure of Human Carbonic Anhydrase II complexed with 5,6-DIHYDRO-BENZO[H]CINNOLIN-3-YLAMINE 分子名称: (4S)-4-methyl-N-(4-sulfamoylphenyl)hexanamide, Carbonic anhydrase 2, DIMETHYL SULFOXIDE, ... 著者 Aggarwal, M, McKenna, R. 登録日 2010-09-23 公開日 2011-08-10 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (1.47 Å) 主引用文献 Anticonvulsant 4-aminobenzenesulfonamide derivatives with branched-alkylamide moieties: X-ray crystallography and inhibition studies of human carbonic anhydrase isoforms I, II, VII, and XIV. J.Med.Chem., 54, 2011
1RBP	CRYSTALLOGRAPHIC REFINEMENT OF HUMAN SERUM RETINOL BINDING PROTEIN AT 2 ANGSTROMS RESOLUTION 分子名称: PLASMA RETINOL-BINDING PROTEIN PRECURSOR, RETINOL 著者 Jones, T.A, Newcomer, M.E, Cowan, S.W. 登録日 1990-04-02 公開日 1991-07-15 最終更新日 2024-11-06 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Crystallographic refinement of human serum retinol binding protein at 2A resolution. Proteins, 8, 1990
9FUB	Wobbly CODH/ACS in the carbonylated state 分子名称: CO-methylating acetyl-CoA synthase, Carbon monoxide dehydrogenase, Fe(3)-Ni(1)-S(4) cluster, ... 著者 Ruickoldt, J, Wendler, P, Dobbek, H. 登録日 2024-06-26 公開日 2025-07-09 実験手法 ELECTRON MICROSCOPY (1.98 Å) 主引用文献 The CODH/ACS complex caught in action To Be Published
3I4M	8-oxoguanine containing RNA polymerase II elongation complex D 分子名称: DNA (5'-D(*AP*G*CP*TP*CP*AP*AP*GP*TP*AP*CP*TP*TP*AP*(8OG)P*GP*CP*CP*(BRU)P*GP*GP*TP*CP*AP*TP*T)-3'), DNA (5'-D(*AP*GP*TP*AP*CP*TP*TP*GP*AP*GP*CP*T)-3'), DNA-directed RNA polymerase II subunit RPB1, ... 著者 Damsma, G.E, Cramer, P. 登録日 2009-07-02 公開日 2009-09-08 最終更新日 2024-10-30 実験手法 X-RAY DIFFRACTION (3.7 Å) 主引用文献 Molecular basis of transcriptional mutagenesis at 8-oxoguanine J.Biol.Chem., 284, 2009
1GYQ	CRYSTAL STRUCTURE OF GLYCOSOMAL GLYCERALDEHYDE FROM LEISHMANIA MEXICANA IN COMPLEX WITH N6-BENZYL-NAD 分子名称: N6-BENZYL-NICOTINAMIDE-ADENINE-DINUCLEOTIDE, PROTEIN (GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE) 著者 Suresh, S, Hol, W. 登録日 1999-03-05 公開日 1999-03-16 最終更新日 2023-08-09 実験手法 X-RAY DIFFRACTION (3.4 Å) 主引用文献 Structure-based design of submicromolar, biologically active inhibitors of trypanosomatid glyceraldehyde-3-phosphate dehydrogenase. Proc.Natl.Acad.Sci.USA, 96, 1999
9FHT	Bacteroides ovatus polysaccharide lyase family 38 (BoPL38) wild type in complex hexaguluronic acid at pH 3.5 分子名称: Alginate lyase family protein, SULFATE ION, alpha-L-gulopyranuronic acid-(1-4)-alpha-L-gulopyranuronic acid-(1-4)-alpha-L-gulopyranuronic acid-(1-4)-alpha-L-gulopyranuronic acid 著者 Tandrup, T, Wilkens, C. 登録日 2024-05-28 公開日 2025-07-09 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 The Swiss Army Knife of Alginate Metabolism: Mechanistic Analysis of a Mixed-Function Polysaccharide Lyase/Epimerase of the Human Gut Microbiota. J.Am.Chem.Soc., 2025
9FU9	Wobbly CODH/ACS in the methylated state 分子名称: CO-methylating acetyl-CoA synthase, Carbon monoxide dehydrogenase, Fe(3)-Ni(1)-S(4) cluster, ... 著者 Ruickoldt, J, Wendler, P, Dobbek, H. 登録日 2024-06-26 公開日 2025-07-09 実験手法 ELECTRON MICROSCOPY (2.24 Å) 主引用文献 The CODH/ACS complex caught in action To Be Published
7C3O	Crystal structure of TT109 from CANDIDA ALBICANS 分子名称: ACETYL COENZYME *A, DI(HYDROXYETHYL)ETHER, GLYCEROL, ... 著者 Chen, Y.P, Lei, J.H, Lu, D.R, Su, D. 登録日 2020-05-13 公開日 2021-05-19 最終更新日 2024-10-09 実験手法 X-RAY DIFFRACTION (1.89 Å) 主引用文献 Crystal structure of TT109 from CANDIDA ALBICANS To Be Published

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