6RRG

Human Carbonic Anhydrase II in complex with fluorinated benzenesulfonamide

Summary for 6RRG

Entry DOI	10.2210/pdb6rrg/pdb
Related	6RIT 6RJJ 6RKN 6RNP 6ROE 6RQI
Descriptor	Carbonic anhydrase 2, ZINC ION, MERCURY (II) ION, ... (8 entities in total)
Functional Keywords	inhibitor, complex, co2 conversion, lyase
Biological source	Homo sapiens (Human)
Total number of polymer chains	1
Total formula weight	31163.38
Authors	Gloeckner, S.,Heine, A.,Klebe, G. (deposition date: 2019-05-17, release date: 2020-04-15, Last modification date: 2024-01-24)
Primary citation	Glockner, S.,Ngo, K.,Wagner, B.,Heine, A.,Klebe, G. The Influence of Varying Fluorination Patterns on the Thermodynamics and Kinetics of Benzenesulfonamide Binding to Human Carbonic Anhydrase II. Biomolecules, 10:-, 2020 Cited by PubMed: 32230853 DOI: 10.3390/biom10040509 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.127 Å)

Structure validation