PDB: 47065 件ウェブページステータス検索Chemie searchBIRD

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5TTO	X-ray crystal structure of PPARgamma in complex with SR1643 分子名称: 4-bromo-N-{3,5-dichloro-4-[(quinolin-3-yl)oxy]phenyl}-2,5-difluorobenzene-1-sulfonamide, Peroxisome proliferator-activated receptor gamma 著者 Bruning, J.B, Frkic, R.L, Griffin, P, Kamenecka, T, Abell, A. 登録日 2016-11-04 公開日 2017-05-24 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.246 Å) 主引用文献 Structure-Activity Relationship of 2,4-Dichloro-N-(3,5-dichloro-4-(quinolin-3-yloxy)phenyl)benzenesulfonamide (INT131) Analogs for PPAR gamma-Targeted Antidiabetics. J. Med. Chem., 60, 2017
6AVM	STRUCTURE OF HIV-1 REVERSE TRANSCRIPTASE (RT) TERNARY COMPLEX WITH A DOUBLE STRANDED DNA AND AN INCOMING D4TTP AT PH 9.5 WITH CROSS-LINKING TO SECOND BASE TEMPLATE OVERHANG 分子名称: 2',3'-DEHYDRO-2',3'-DEOXY-THYMIDINE 5'-TRIPHOSPHATE, DNA (27-MER), DNA (5'-D(*A*CP*AP*GP*TP*CP*CP*CP*TP*GP*TP*TP*CP*GP*GP*GP*CP*GP*CP*CP*(DDG))-3'), ... 著者 Martinez, S.E, Das, K, Arnold, E. 登録日 2017-09-03 公開日 2018-08-15 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.502 Å) 主引用文献 Structure of HIV-1 reverse transcriptase/d4TTP complex: Novel DNA cross-linking site and pH-dependent conformational changes. Protein Sci., 28, 2019
6AX7	The crystal structure of a lysyl hydroxylase from Acanthamoeba polyphaga mimivirus 分子名称: FE (II) ION, Procollagen lysyl hydroxylase and glycosyltransferase 著者 Guo, H, Tsai, C, Miller, M.D, Alvarado, S, Tainer, J.A, Phillips Jr, G.N, Kurie, J.M. 登録日 2017-09-06 公開日 2018-02-21 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.002 Å) 主引用文献 Pro-metastatic collagen lysyl hydroxylase dimer assemblies stabilized by Fe2+-binding. Nat Commun, 9, 2018
4XY6	Crystal Structure of mutant (Thr68Ala) Hypothetical Thioesterase Protein SP_1851 from Streptococcus pneumoniae TIGR4 分子名称: Hypothetical Thioesterase Protein SP_1851 著者 Khandokar, Y.B, Srivastava, P, Forwood, J.K. 登録日 2015-02-02 公開日 2015-05-06 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Crystal Structure of mutant (Thr68Ala) Hypothetical Thioesterase Protein SP_1851 from Streptococcus pneumoniae TIGR4 To Be Published
5TW9	1.50 Angstrom Crystal Structure of C-terminal Fragment (residues 322-384) of Iron Uptake System Component EfeO from Yersinia pestis. 分子名称: 1,2-ETHANEDIOL, IODIDE ION, Iron uptake system component EfeO 著者 Minasov, G, Shuvalova, L, Flores, K, Dubrovska, I, Grimshaw, S, Kwon, K, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) 登録日 2016-11-11 公開日 2016-11-30 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 1.50 Angstrom Crystal Structure of C-terminal Fragment (residues 322-384) of Iron Uptake System Component EfeO from Yersinia pestis. To Be Published
4XZ2	Human platelet phosphofructokinase in an R-state in complex with ADP and F6P, crystal form I 分子名称: 1,6-di-O-phosphono-beta-D-fructofuranose, 6-O-phosphono-beta-D-fructofuranose, ADENOSINE-5'-DIPHOSPHATE, ... 著者 Kloos, M, Strater, N. 登録日 2015-02-03 公開日 2015-06-03 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.67 Å) 主引用文献 Crystal structure of human platelet phosphofructokinase-1 locked in an activated conformation. Biochem.J., 469, 2015
6AY0	Crystal structure of H108A peptidylglycine alpha-hydroxylating monooxygenase (PHM) soaked with peptide 分子名称: COPPER (II) ION, Peptidyl-glycine alpha-amidating monooxygenase 著者 Maheshwari, S, Rudzka, K, Gabelli, S.B, Amzel, L.M. 登録日 2017-09-07 公開日 2018-07-18 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Effects of copper occupancy on the conformational landscape of peptidylglycine alpha-hydroxylating monooxygenase. Commun Biol, 1, 2018
5TX1	Cryo-Electron microscopy structure of species-D human adenovirus 26 分子名称: Fiber, Hexon protein, PIIIa, ... 著者 Reddy, V, Yu, X, Veesler, D. 登録日 2016-11-15 公開日 2017-05-31 最終更新日 2024-03-13 実験手法 ELECTRON MICROSCOPY (3.7 Å) 主引用文献 Cryo-EM structure of human adenovirus D26 reveals the conservation of structural organization among human adenoviruses. Sci Adv, 3, 2017
4XXS	Crystal structure of BACE1 with a pyrazole-substituted tetrahydropyran thioamidine 分子名称: (4aR,6R,8aS)-8a-(2,4-difluorophenyl)-6-(1-methyl-1H-pyrazol-4-yl)-4,4a,5,6,8,8a-hexahydropyrano[3,4-d][1,3]thiazin-2-amine, Beta-secretase 1, DIMETHYL SULFOXIDE, ... 著者 Parris, K.D, Pandit, J. 登録日 2015-01-30 公開日 2015-04-01 最終更新日 2015-04-22 実験手法 X-RAY DIFFRACTION (1.86 Å) 主引用文献 Utilizing Structures of CYP2D6 and BACE1 Complexes To Reduce Risk of Drug-Drug Interactions with a Novel Series of Centrally Efficacious BACE1 Inhibitors. J.Med.Chem., 58, 2015
4XY8	Crystal Structure of the bromodomain of BRD9 in complex with a 2-amine-9H-purine ligand 分子名称: 6-(5-bromo-2-methoxyphenyl)-9H-purin-2-amine, BROMIDE ION, Bromodomain-containing protein 9 著者 Picaud, S, von Delft, F, Edwards, A.M, Arrowsmith, C.H, Bountra, C, Filippakopoulos, P, Structural Genomics Consortium (SGC) 登録日 2015-02-02 公開日 2015-03-11 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 9H-Purine Scaffold Reveals Induced-Fit Pocket Plasticity of the BRD9 Bromodomain. J.Med.Chem., 58, 2015
2N6M	Structural elucidation of the frog skin-derived peptide Esculentin-1a[Esc(1-21)NH2] inLipopolysaccharide and correlation with their function 分子名称: Esculentin-1A 著者 Ghosh, A, Bhunia, A. 登録日 2015-08-26 公開日 2016-03-02 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 NMR structure and binding of esculentin-1a (1-21)NH2 and its diastereomer to lipopolysaccharide: Correlation with biological functions Biochim.Biophys.Acta, 1858, 2015
2NCP	NMR solution structure for the C-terminal domain of Tetrahymena Tcb2 in the presence of calcium 分子名称: 25 kDa calcium-binding protein 著者 Fowler, A, Kilpatrick, A.M. 登録日 2016-04-11 公開日 2016-08-17 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 Solution NMR structures of the C-domain of Tetrahymena cytoskeletal protein Tcb2 reveal distinct calcium-induced structural rearrangements. Proteins, 84, 2016
2N70	Two-fold symmetric structure of the 18-60 construct of S31N M2 from Influenza A in lipid bilayers 分子名称: Matrix protein 2 著者 Andreas, L.B, Reese, M, Eddy, M.T, Gelev, V, Ni, Q, Miller, E.A, Emsley, L, Pintacuda, G, Chou, J.J, Griffin, R.G. 登録日 2015-09-01 公開日 2015-09-23 最終更新日 2024-05-15 実験手法 SOLID-STATE NMR 主引用文献 Structure and Mechanism of the Influenza A M218-60 Dimer of Dimers. J.Am.Chem.Soc., 137, 2015
4Y4Z	Endothiapepsin in complex with fragment 73 分子名称: (1Z)-N,N-diethylethanimidamide, 1,2-ETHANEDIOL, ACETATE ION, ... 著者 Schiebel, J, Heine, A, Klebe, G. 登録日 2015-02-11 公開日 2016-03-02 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.48 Å) 主引用文献 Crystallographic Fragment Screening of an Entire Library To Be Published
4Y58	Endothiapepsin in complex with fragment 260 分子名称: ACETATE ION, DI(HYDROXYETHYL)ETHER, DIMETHYL SULFOXIDE, ... 著者 Wang, X, Heine, A, Klebe, G. 登録日 2015-02-11 公開日 2016-03-02 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.17 Å) 主引用文献 Crystallographic Fragment Sreening of an Entire Library to be published
4Y5K	Endothiapepsin in complex with fragment 274 分子名称: (1S)-2-amino-1-(4-fluorophenyl)ethanol, ACETATE ION, DIMETHYL SULFOXIDE, ... 著者 Wang, X, Heine, A, Klebe, G. 登録日 2015-02-11 公開日 2016-03-02 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.439 Å) 主引用文献 Crystallographic Fragment Sreening of an Entire Library to be published
4Y5W	Transcription factor-DNA complex 分子名称: DNA (5'-D(P*AP*TP*GP*GP*AP*TP*TP*TP*CP*CP*TP*AP*GP*GP*AP*AP*GP*AP*CP*AP*A)-3'), DNA (5'-D(P*TP*TP*GP*TP*CP*TP*TP*CP*CP*TP*AP*GP*GP*AP*AP*AP*TP*CP*CP*AP*T)-3'), Signal transducer and activator of transcription 6 著者 Li, J, Niu, F, Ouyang, S, Liu, Z. 登録日 2015-02-12 公開日 2016-02-17 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (3.104 Å) 主引用文献 Structural basis for DNA recognition by STAT6 Proc.Natl.Acad.Sci.USA, 113, 2016
2NBW	Solution structure of the Rpn1 T1 site with the Rad23 UBL domain 分子名称: 26S proteasome regulatory subunit RPN1, UV excision repair protein RAD23 著者 Chen, X, Walters, K.J. 登録日 2016-03-14 公開日 2016-07-20 最終更新日 2024-05-01 実験手法 SOLUTION NMR 主引用文献 Structures of Rpn1 T1:Rad23 and hRpn13:hPLIC2 Reveal Distinct Binding Mechanisms between Substrate Receptors and Shuttle Factors of the Proteasome. Structure, 24, 2016
4Y6U	Mycobacterial protein 分子名称: 1,2-ETHANEDIOL, 3-PHOSPHOGLYCERIC ACID, CHLORIDE ION, ... 著者 Albesa-Jove, D, Rodrigo-Unzueta, A, Cifuente, J.O, Urresti, S, Comino, N, Sancho-Vaello, E, Guerin, M.E. 登録日 2015-02-13 公開日 2015-07-15 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.271 Å) 主引用文献 A Native Ternary Complex Trapped in a Crystal Reveals the Catalytic Mechanism of a Retaining Glycosyltransferase. Angew.Chem.Int.Ed.Engl., 54, 2015
2NAD	HIGH RESOLUTION STRUCTURES OF HOLO AND APO FORMATE DEHYDROGENASE 分子名称: AZIDE ION, NAD-DEPENDENT FORMATE DEHYDROGENASE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ... 著者 Lamzin, V.S, Dauter, Z, Popov, V.O, Harutyunyan, E.H, Wilson, K.S. 登録日 1994-07-06 公開日 1995-01-26 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 High resolution structures of holo and apo formate dehydrogenase. J.Mol.Biol., 236, 1994
6B0X	Capsid protein and C-terminal part of scaffolding protein in the Staphylococcus aureus phage 80alpha procapsid 分子名称: Major head protein, Scaffold protein 著者 Kizziah, J.L, Dearborn, A.D, Dokland, T. 登録日 2017-09-15 公開日 2017-10-18 最終更新日 2024-03-13 実験手法 ELECTRON MICROSCOPY (3.8 Å) 主引用文献 Competing scaffolding proteins determine capsid size during mobilization ofStaphylococcus aureuspathogenicity islands. Elife, 6, 2017
6ANI	Coltuximab Fab in complex with anti-Kappa VHH domain 分子名称: Anti-Kappa VHH domain, Coltuximab Fab heavy chain, Coltuximab Fab light chain, ... 著者 Ereno Orbea, J, Sicard, T, Julien, J.-P. 登録日 2017-08-13 公開日 2018-01-31 最終更新日 2019-10-16 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Structural Basis of Enhanced Crystallizability Induced by a Molecular Chaperone for Antibody Antigen-Binding Fragments. J. Mol. Biol., 430, 2018
6AP1	Vps4p-Vta1p complex with peptide binding to the central pore of Vps4p 分子名称: ACE-ASP-GLU-ILE-VAL-ASN-LYS-VAL-LEU-NH2, ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, ... 著者 Han, H, Monroe, N, Shen, P, Sundquist, W.I, Hill, C.P. 登録日 2017-08-16 公開日 2017-12-06 最終更新日 2018-07-18 実験手法 ELECTRON MICROSCOPY (3.2 Å) 主引用文献 The AAA ATPase Vps4 binds ESCRT-III substrates through a repeating array of dipeptide-binding pockets. Elife, 6, 2017
5U5W	CcP gateless cavity 分子名称: 3-methylquinolin-4-amine, PROTOPORPHYRIN IX CONTAINING FE, Peroxidase 著者 Fischer, M, Shoichet, B.K. 登録日 2016-12-07 公開日 2017-02-01 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (1.29 Å) 主引用文献 Testing inhomogeneous solvation theory in structure-based ligand discovery. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5UDO	Crystal structure of the coiled-coil domain from Listeria Innocua Phage Integrase (Tetragonal Form II) 分子名称: A118 serine integrase 著者 Gupta, K, Yuan, J.B, Sharp, R, Van Duyne, G.D. 登録日 2016-12-28 公開日 2017-06-07 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.541 Å) 主引用文献 Coiled-coil interactions mediate serine integrase directionality. Nucleic Acids Res., 45, 2017

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