PDB: 46200 件ウェブページステータス検索Chemie searchBIRD

---

7UG1	CDK2 liganded with para chloro ANS 分子名称: 1,2-ETHANEDIOL, 8-(4-chloroanilino)naphthalene-1-sulfonic acid, Cyclin-dependent kinase 2, ... 著者 Schonbrunn, E, Martin, M. 登録日 2022-03-23 公開日 2023-04-12 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.84 Å) 主引用文献 Allosteric inhibitors of CDK2 To Be Published
3JBV	Mechanisms of Ribosome Stalling by SecM at Multiple Elongation Steps 分子名称: 30S ribosomal protein S10, 30S ribosomal protein S11, 30S ribosomal protein S12, ... 著者 Zhang, J, Pan, X.J, Yan, K.G, Sun, S, Gao, N, Sui, S.F. 登録日 2015-10-16 公開日 2016-01-27 最終更新日 2023-12-27 実験手法 ELECTRON MICROSCOPY (3.32 Å) 主引用文献 Mechanisms of ribosome stalling by SecM at multiple elongation steps Elife, 4, 2015
2ZFZ	Crystal structure of the C-terminal domain hexamer of ArgR from Mycobacterium tuberculosis in complex with arginine 分子名称: ARGININE, Arginine repressor, GUANIDINE 著者 Cherney, L.T, Cherney, M.M, Garen, C.R, Lu, G.J, James, M.N.G, TB Structural Genomics Consortium (TBSGC) 登録日 2008-01-16 公開日 2008-02-12 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Structure of the C-terminal domain of the arginine repressor protein from Mycobacterium tuberculosis. Acta Crystallogr.,Sect.D, 64, 2008
3JCJ	Structures of ribosome-bound initiation factor 2 reveal the mechanism of subunit association 分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... 著者 Sprink, T, Ramrath, D.J.F, Yamamoto, H, Yamamoto, K, Loerke, J, Ismer, J, Hildebrand, P.W, Scheerer, P, Buerger, J, Mielke, T, Spahn, C.M.T. 登録日 2015-12-18 公開日 2016-03-09 最終更新日 2024-10-09 実験手法 ELECTRON MICROSCOPY (3.7 Å) 主引用文献 Structures of ribosome-bound initiation factor 2 reveal the mechanism of subunit association. Sci Adv, 2, 2016
7VDU	The structure of cyclin-dependent kinase 2 (CDK2) in complex with Compound 1 分子名称: Cyclin-dependent kinase 2, [1-[3-fluoranyl-4-[(2-piperidin-4-yloxy-1,6-naphthyridin-7-yl)amino]phenyl]pyrazol-3-yl]methanol 著者 Malojcic, G, Clugston, S.L, Daniels, M, Harmange, J.C, Ledeborer, M. 登録日 2021-09-07 公開日 2022-03-09 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.53 Å) 主引用文献 Discovery and Optimization of Highly Selective Inhibitors of CDK5. J.Med.Chem., 65, 2022
3O8H	EthR from Mycobacterium tuberculosis in complex with compound BDM14950 分子名称: 4-iodo-N-[(1-{2-oxo-2-[4-(3-thiophen-2-yl-1,2,4-oxadiazol-5-yl)piperidin-1-yl]ethyl}-1H-1,2,3-triazol-4-yl)methyl]benzenesulfonamide, Transcriptional Regulatory Repressor protein (TETR-Family) EthR 著者 Willand, N, Desroses, M, Toto, P, Diri, B, Lens, Z, Villeret, V, Rucktooa, P, Locht, C, Baulard, A, Deprez, B. 登録日 2010-08-03 公開日 2010-09-01 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Exploring drug target flexibility using in situ click chemistry: application to a mycobacterial transcriptional regulator. Acs Chem.Biol., 5, 2010
3JCN	Structures of ribosome-bound initiation factor 2 reveal the mechanism of subunit association: Initiation Complex I 分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... 著者 Sprink, T, Ramrath, D.J.F, Yamamoto, H, Yamamoto, K, Loerke, J, Ismer, J, Hildebrand, P.W, Scheerer, P, Buerger, J, Mielke, T, Spahn, C.M.T. 登録日 2016-01-04 公開日 2016-03-09 最終更新日 2018-07-18 実験手法 ELECTRON MICROSCOPY (4.6 Å) 主引用文献 Structures of ribosome-bound initiation factor 2 reveal the mechanism of subunit association. Sci Adv, 2, 2016
5UQ2	Crystal structure of human Cdk2-Spy1 complex 分子名称: Cyclin-dependent kinase 2, Speedy protein A 著者 McGrath, D.A, Tripathi, S.M, Rubin, S.M. 登録日 2017-02-06 公開日 2017-07-05 最終更新日 2017-08-09 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Structural basis of divergent cyclin-dependent kinase activation by Spy1/RINGO proteins. EMBO J., 36, 2017
3JA1	Activation of GTP Hydrolysis in mRNA-tRNA Translocation by Elongation Factor G 分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... 著者 Li, W, Liu, Z, Koripella, R.K, Langlois, R, Sanyal, S, Frank, J. 登録日 2015-03-30 公開日 2015-07-01 最終更新日 2024-02-21 実験手法 ELECTRON MICROSCOPY (3.6 Å) 主引用文献 Activation of GTP hydrolysis in mRNA-tRNA translocation by elongation factor G. Sci Adv, 1, 2015
4D7M	TetR(D) in complex with anhydrotetracycline and magnesium 分子名称: 5A,6-ANHYDROTETRACYCLINE, CHLORIDE ION, MAGNESIUM ION, ... 著者 Werten, S, Dalm, D, Palm, G.J, Hinrichs, W. 登録日 2014-11-25 公開日 2014-12-10 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (1.55 Å) 主引用文献 Tetracycline Repressor Allostery Does not Depend on Divalent Metal Recognition. Biochemistry, 53, 2014
5W3X	Crystal structure of PopP2 in complex with IP6, AcCoA and the WRKY domain of RRS1-R . 分子名称: ACETYL COENZYME *A, Disease resistance protein RRS1, GLYCEROL, ... 著者 Zhang, Z.M, Gao, L, Song, J. 登録日 2017-06-08 公開日 2017-08-09 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Mechanism of host substrate acetylation by a YopJ family effector. Nat Plants, 3, 2017
2KQS	Phosphorylation of SUMO-interacting motif by CK2 enhances Daxx SUMO binding activity 分子名称: Death domain-associated protein 6, Small ubiquitin-related modifier 1 著者 Naik, M.T, Huang, T.H, Shih, H. 登録日 2009-11-17 公開日 2010-12-01 最終更新日 2024-05-01 実験手法 SOLUTION NMR 主引用文献 Structural and functional roles of Daxx SIM phosphorylation in SUMO paralog-selective binding and apoptosis modulation. Mol.Cell, 42, 2011
1QVT	CRYSTAL STRUCTURE OF THE MULTIDRUG BINDING TRANSCRIPTIONAL REPRESSOR QACR BOUND TO THE DRUG PROFLAVINE 分子名称: PROFLAVIN, SULFATE ION, Transcriptional regulator qacR 著者 Schumacher, M.A, Miller, M.C, Brennan, R.G. 登録日 2003-08-28 公開日 2004-08-03 最終更新日 2023-08-16 実験手法 X-RAY DIFFRACTION (2.89 Å) 主引用文献 Structural mechanism of the simultaneous binding of two drugs to a multidrug-binding protein Embo J., 23, 2004
2BTO	Structure of BtubA from Prosthecobacter dejongeii 分子名称: GUANOSINE-5'-TRIPHOSPHATE, THIOREDOXIN 1, TUBULIN BTUBA 著者 Schlieper, D, Lowe, J. 登録日 2005-06-04 公開日 2005-06-23 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Structure of Bacterial Tubulin Btuba/B: Evidence for Horizontal Gene Transfer. Proc.Natl.Acad.Sci.USA, 102, 2005
2DCE	Solution structure of the SWIRM domain of human KIAA1915 protein 分子名称: KIAA1915 protein 著者 Yoneyama, M, Tochio, N, Umehara, T, Koshiba, S, Inoue, M, Tanaka, A, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) 登録日 2006-01-06 公開日 2006-07-06 最終更新日 2024-05-29 実験手法 SOLUTION NMR 主引用文献 Structural and Functional Differences of SWIRM Domain Subtypes J.Mol.Biol., 369, 2007
4OGF	Crystal Structure of Human DJ-1 with glyoxylate as substrate analog 分子名称: Protein DJ-1 著者 Choi, D, Kim, J, Ryu, K.-S, Park, C. 登録日 2014-01-16 公開日 2014-10-15 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Stereospecific mechanism of DJ-1 glyoxalases inferred from their hemithioacetal-containing crystal structures. Febs J., 281, 2014
7EGG	TFIID lobe B subcomplex 分子名称: Transcription initiation factor TFIID subunit 10, Transcription initiation factor TFIID subunit 12, Transcription initiation factor TFIID subunit 4, ... 著者 Chen, X, Wu, Z, Li, J, Zhao, D, Xu, Y. 登録日 2021-03-24 公開日 2021-05-05 最終更新日 2024-06-05 実験手法 ELECTRON MICROSCOPY (2.77 Å) 主引用文献 Structural insights into preinitiation complex assembly on core promoters. Science, 372, 2021
2DQL	Crystal structure of the circadian clock associated protein Pex from anabaena 分子名称: PHOSPHATE ION, Pex protein 著者 Kurosawa, S, Kouyama, T. 登録日 2006-05-29 公開日 2007-05-29 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Functionally important structural elements of the cyanobacterial clock-related protein Pex. Genes Cells, 14, 2009
8SCB	Terminating ribosome with SRI-41315 分子名称: (2S,4aS)-2-cyclobutyl-10-methyl-3-phenyl-2,10-dihydropyrimido[4,5-b]quinoline-4,5(3H,4aH)-dione, 18S_rRNA, 28S_rRNA, ... 著者 Yip, M.C.J, Coelho, J.P.L, Oltion, K, Tauton, J, Shao, S. 登録日 2023-04-05 公開日 2023-12-27 最終更新日 2024-10-09 実験手法 ELECTRON MICROSCOPY (2.5 Å) 主引用文献 The eRF1 degrader SRI-41315 acts as a molecular glue at the ribosomal decoding center. Nat.Chem.Biol., 20, 2024
7D80	Molecular model of the cryo-EM structure of 70S ribosome in complex with peptide deformylase, trigger factor, and methionine aminopeptidase 分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... 著者 Akbar, S, Bhakta, S, Sengupta, J. 登録日 2020-10-06 公開日 2021-04-07 最終更新日 2024-05-29 実験手法 ELECTRON MICROSCOPY (4.1 Å) 主引用文献 Structural insights into the interplay of protein biogenesis factors with the 70S ribosome. Structure, 29, 2021
7DVQ	Cryo-EM Structure of the Activated Human Minor Spliceosome (minor Bact Complex) 分子名称: 116 kDa U5 small nuclear ribonucleoprotein component, 5'-O-[(S)-hydroxy{[(R)-hydroxy{[(S)-hydroxy(methoxy)phosphoryl]oxy}phosphoryl]oxy}phosphoryl]guanosine, Armadillo repeat-containing protein 7, ... 著者 Bai, R, Wan, R, Wang, L, Xu, K, Zhang, Q, Lei, J, Shi, Y. 登録日 2021-01-14 公開日 2021-03-31 実験手法 ELECTRON MICROSCOPY (2.89 Å) 主引用文献 Structure of the activated human minor spliceosome. Science, 371, 2021
8CGV	Tiamulin bound to the 50S subunit 分子名称: 23S rRNA, 50S ribosomal protein L15, 50S ribosomal protein L25, ... 著者 Paternoga, H, Crowe-McAuliffe, C, Novacek, J, Wilson, D.N. 登録日 2023-02-06 公開日 2023-08-02 最終更新日 2023-11-15 実験手法 ELECTRON MICROSCOPY (1.66 Å) 主引用文献 Structural conservation of antibiotic interaction with ribosomes. Nat.Struct.Mol.Biol., 30, 2023
6XE0	Cryo-EM structure of NusG-CTD bound to 70S ribosome (30S: NusG-CTD fragment) 分子名称: 16s rRNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ... 著者 Washburn, R, Zuber, P, Sun, M, Hashem, Y, Shen, B, Li, W, Harvey, S, Acosta-Reyes, F.J, Knauer, S.H, Frank, J, Gottesman, M.E. 登録日 2020-06-11 公開日 2020-07-29 最終更新日 2024-03-06 実験手法 ELECTRON MICROSCOPY (6.8 Å) 主引用文献 Escherichia coli NusG Links the Lead Ribosome with the Transcription Elongation Complex. Iscience, 23, 2020
6NJT	Mouse endonuclease G mutant - H97A 分子名称: CHLORIDE ION, Endonuclease G, mitochondrial, ... 著者 Vander Zanden, C.M, Ho, E.N, Czarny, R.S, Robertson, A.B, Ho, P.S. 登録日 2019-01-04 公開日 2020-01-08 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.07 Å) 主引用文献 Structural adaptation of vertebrate endonuclease G for 5-hydroxymethylcytosine recognition and function. Nucleic Acids Res., 48, 2020
1BUH	CRYSTAL STRUCTURE OF THE HUMAN CDK2 KINASE COMPLEX WITH CELL CYCLE-REGULATORY PROTEIN CKSHS1 分子名称: PROTEIN (CDK2 HUMAN), PROTEIN (CKSHS1 HUMAN) 著者 Bourne, Y, Tainer, J.A. 登録日 1998-09-03 公開日 1998-09-09 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Crystal structure and mutational analysis of the human CDK2 kinase complex with cell cycle-regulatory protein CksHs1. Cell(Cambridge,Mass.), 84, 1996

<950951952953954955956957958959960961962963964965>