3O8H
EthR from Mycobacterium tuberculosis in complex with compound BDM14950
Summary for 3O8H
Entry DOI | 10.2210/pdb3o8h/pdb |
Related | 1U9N 3O8G |
Descriptor | Transcriptional Regulatory Repressor protein (TETR-Family) EthR, 4-iodo-N-[(1-{2-oxo-2-[4-(3-thiophen-2-yl-1,2,4-oxadiazol-5-yl)piperidin-1-yl]ethyl}-1H-1,2,3-triazol-4-yl)methyl]benzenesulfonamide (3 entities in total) |
Functional Keywords | tetr-family, transcriptional regulatory repressor, dna, transcription |
Biological source | Mycobacterium tuberculosis |
Total number of polymer chains | 1 |
Total formula weight | 26592.57 |
Authors | Willand, N.,Desroses, M.,Toto, P.,Diri, B.,Lens, Z.,Villeret, V.,Rucktooa, P.,Locht, C.,Baulard, A.,Deprez, B. (deposition date: 2010-08-03, release date: 2010-09-01, Last modification date: 2024-02-21) |
Primary citation | Willand, N.,Desroses, M.,Toto, P.,Dirie, B.,Lens, Z.,Villeret, V.,Rucktooa, P.,Locht, C.,Baulard, A.,Deprez, B. Exploring drug target flexibility using in situ click chemistry: application to a mycobacterial transcriptional regulator. Acs Chem.Biol., 5:1007-1013, 2010 Cited by PubMed: 20704273DOI: 10.1021/cb100177g PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.9 Å) |
Structure validation
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