PDB: 46006 件ウェブページステータス検索Chemie searchBIRD

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4EZ7	CDK2 in complex with staurosporine and 2 molecules of 8-anilino-1-naphthalene sulfonic acid 分子名称: 1,2-ETHANEDIOL, 8-ANILINO-1-NAPHTHALENE SULFONATE, Cyclin-dependent kinase 2, ... 著者 Alam, R, Martin, M.P, Zhu, J.-Y, Schonbrunn, E. 登録日 2012-05-02 公開日 2012-08-22 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.49 Å) 主引用文献 A Novel Approach to the Discovery of Small-Molecule Ligands of CDK2. Chembiochem, 13, 2012
4WIA	Crystal structure of flagellar accessory protein FlaH from Methanocaldococcus jannaschii 分子名称: GLYCEROL, Putative flagella-related protein H, SULFATE ION 著者 Meshcheryakov, V.A, Wolf, M. 登録日 2014-09-25 公開日 2015-10-07 最終更新日 2020-02-05 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Crystal structure of the flagellar accessory protein FlaH of Methanocaldococcus jannaschii suggests a regulatory role in archaeal flagellum assembly. Protein Sci., 25, 2016
4WK1	Crystal structure of Staphylococcus aureus PstA in complex with c-di-AMP 分子名称: (2R,3R,3aS,5R,7aR,9R,10R,10aS,12R,14aR)-2,9-bis(6-amino-9H-purin-9-yl)octahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8 ]tetraoxadiphosphacyclododecine-3,5,10,12-tetrol 5,12-dioxide, CALCIUM ION, PstA 著者 Mueller, M, Hopfner, K.-P, Witte, G. 登録日 2014-10-01 公開日 2014-11-26 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.98 Å) 主引用文献 c-di-AMP recognition by Staphylococcus aureus PstA. Febs Lett., 589, 2015
4WK3	Structure of Staphyloccus aureus PstA 分子名称: CHLORIDE ION, PstA 著者 Mueller, M, Hopfner, K.-P, Witte, G. 登録日 2014-10-01 公開日 2014-11-26 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 c-di-AMP recognition by Staphylococcus aureus PstA. Febs Lett., 589, 2015
4WL9	Time Resolved Serial Femtosecond Crystallography Captures High Resolution Intermediates of PYP 分子名称: 4'-HYDROXYCINNAMIC ACID, Photoactive yellow protein 著者 Tenboer, J, Schmidt, M. 登録日 2014-10-06 公開日 2014-12-17 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Time-resolved serial crystallography captures high-resolution intermediates of photoactive yellow protein. Science, 346, 2014
4GCJ	CDK2 in complex with inhibitor RC-3-89 分子名称: 1,2-ETHANEDIOL, 4-{[4-amino-5-(2-nitrobenzoyl)-1,3-thiazol-2-yl]amino}benzenesulfonamide, Cyclin-dependent kinase 2 著者 Betzi, S, Alam, R, Han, H, Becker, A, Schonbrunn, E. 登録日 2012-07-30 公開日 2012-10-31 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.42 Å) 主引用文献 Development of highly potent and selective diaminothiazole inhibitors of cyclin-dependent kinases. J.Med.Chem., 56, 2013
4WFX	Coxsackievirus B3 Polymerase - F232L Mutant - NaCl Crystal Form 分子名称: RNA-directed RNA polymerase, SODIUM ION 著者 Peersen, O.B, McDonald, S.M. 登録日 2014-09-17 公開日 2014-10-22 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.808 Å) 主引用文献 Structure-Function Relationships Underlying the Replication Fidelity of Viral RNA-Dependent RNA Polymerases. J.Virol., 89, 2015
4WSB	Bat Influenza A polymerase with bound vRNA promoter 分子名称: Influenza A polymerase vRNA promoter 3' end, Influenza A polymerase vRNA promoter 5' end, PHOSPHATE ION, ... 著者 Cusack, S, Pflug, A, Guilligay, D, Reich, S. 登録日 2014-10-26 公開日 2014-11-19 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.65 Å) 主引用文献 Structural insight into cap-snatching and RNA synthesis by influenza polymerase. Nature, 516, 2014
8TWD	Structure of IraM-bound RssB 分子名称: ACETATE ION, Anti-adapter protein IraM, Regulator of RpoS 著者 Brugger, C, Deaconescu, A.M. 登録日 2023-08-20 公開日 2024-01-10 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (3.3 Å) 主引用文献 IraM remodels the RssB segmented helical linker to stabilize sigma s against degradation by ClpXP. J.Biol.Chem., 300, 2023
4FX3	Crystal Structure of the CDK2/Cyclin A complex with oxindole inhibitor 分子名称: (3Z)-2-oxo-3-[2-(4-sulfamoylphenyl)hydrazinylidene]-2,3-dihydro-1H-indole-5-carboxylic acid, 2,3-DIHYDROXY-1,4-DITHIOBUTANE, Cyclin-A2, ... 著者 Kang, Y.N, Stuckey, J.A. 登録日 2012-07-02 公開日 2013-05-15 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.75 Å) 主引用文献 Crystal Structure of the CDK2/Cyclin A complex with oxindole inhibitor To be Published
4WPB	Vascular endothelial growth factor in complex with alpha/beta-VEGF-1 分子名称: Vascular endothelial growth factor A, alpha/beta-VEGF-1 著者 Kreitler, D.F, Checco, J.W, Gellman, S.H, Forest, K.T. 登録日 2014-10-17 公開日 2015-04-15 最終更新日 2024-07-10 実験手法 X-RAY DIFFRACTION (3.11 Å) 主引用文献 Targeting diverse protein-protein interaction interfaces with alpha / beta-peptides derived from the Z-domain scaffold. Proc.Natl.Acad.Sci.USA, 112, 2015
4WRQ	Crystal Structure of 14-3-3 zeta with Chibby peptide 分子名称: 14-3-3 protein zeta/delta, Chibby 著者 Killoran, R.C, Shilton, B.H, Choy, W.Y. 登録日 2014-10-24 公開日 2015-05-06 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.409 Å) 主引用文献 Structural Analysis of the 14-3-3 zeta /Chibby Interaction Involved in Wnt/ beta-Catenin Signaling. Plos One, 10, 2015
7UYF	Human PRMT5:MEP50 structure with Fragment 4 and MTA Bound 分子名称: 4-methyl-1,5-naphthyridin-2-amine, 5'-DEOXY-5'-METHYLTHIOADENOSINE, CHLORIDE ION, ... 著者 Gunn, R.J, Lawson, J.D, Smith, C.R. 登録日 2022-05-06 公開日 2022-10-05 最終更新日 2024-05-22 実験手法 X-RAY DIFFRACTION (2.82 Å) 主引用文献 Fragment optimization and elaboration strategies - the discovery of two lead series of PRMT5/MTA inhibitors from five fragment hits. Rsc Med Chem, 13, 2022
4WRT	Crystal structure of Influenza B polymerase with bound vRNA promoter (form FluB2) 分子名称: Influenza virus polymerase vRNA promoter 3' end, Influenza virus polymerase vRNA promoter 5' end, PA, ... 著者 Reich, S, Guilligay, D, Pflug, A, Cusack, S. 登録日 2014-10-25 公開日 2014-11-19 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Structural insight into cap-snatching and RNA synthesis by influenza polymerase. Nature, 516, 2014
8DKD	Sliding clamp from M. thermoresistibile 分子名称: Beta sliding clamp 著者 Kapur, M.K, Gray, O.J, Honzatko, R.H, Nelson, S.N. 登録日 2022-07-05 公開日 2023-01-18 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 Interaction of sliding clamp with mycobacterial polymerases To Be Published
4X1D	Ytterbium-bound human serum transferrin 分子名称: GLYCEROL, MALONATE ION, Serotransferrin, ... 著者 Wang, M, Zhang, H, Sun, H. 登録日 2014-11-24 公開日 2015-04-08 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 "Anion clamp" allows flexible protein to impose coordination geometry on metal ions Chem.Commun.(Camb.), 51, 2015
7UY1	HUMAN PRMT5:MEP50 COMPLEX WITH MTA and Fragment 5 Bound 分子名称: 1,2-ETHANEDIOL, 3-methyl-1,5-naphthyridin-2-amine, 5'-DEOXY-5'-METHYLTHIOADENOSINE, ... 著者 Gunn, R.J. 登録日 2022-05-06 公開日 2022-10-05 最終更新日 2024-05-22 実験手法 X-RAY DIFFRACTION (2.66 Å) 主引用文献 Fragment optimization and elaboration strategies - the discovery of two lead series of PRMT5/MTA inhibitors from five fragment hits. Rsc Med Chem, 13, 2022
4X2B	K20A RNA dependent RNA polymerase mutant from Foot-and-Mouth disease Virus complexed with an RNA 分子名称: MAGNESIUM ION, RNA dependent RNA polymerase, RNA primer, ... 著者 Verdaguer, N, Ferrer-Orta, C. 登録日 2014-11-26 公開日 2015-05-06 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.94 Å) 主引用文献 Multifunctionality of a picornavirus polymerase domain: nuclear localization signal and nucleotide recognition. J.Virol., 89, 2015
4WYL	Mutant K18E of 3D polymerase from Foot-and-Moth Disease Virus 分子名称: ACETATE ION, GLYCEROL, MANGANESE (II) ION, ... 著者 Ferrer-Orta, C, Verdaguer, N, de la Higuera, I, Domingo, E. 登録日 2014-11-17 公開日 2015-05-06 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Multifunctionality of a picornavirus polymerase domain: nuclear localization signal and nucleotide recognition. J.Virol., 89, 2015
4WSA	Crystal structure of Influenza B polymerase bound to the vRNA promoter (FluB1 form) 分子名称: Influenza B vRNA promoter 3' end, Influenza B vRNA promoter 5' end, PA, ... 著者 Reich, S, Guilligay, D, Pflug, A, Cusack, S. 登録日 2014-10-26 公開日 2014-11-19 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (3.4 Å) 主引用文献 Structural insight into cap-snatching and RNA synthesis by influenza polymerase. Nature, 516, 2014
1HH2	Crystal structure of NusA from Thermotoga maritima 分子名称: N UTILIZATION SUBSTANCE PROTEIN A 著者 Worbs, M, Bourenkov, G.P, Bartunik, H.D, Huber, R, Wahl, M.C. 登録日 2000-12-18 公開日 2001-10-19 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 An Extended RNA Binding Surface Through Arrayed S1 and Kh Domains in Transcription Factor Nusa Mol.Cell, 7, 2001
7UOH	PRMT5/MEP50 crystal structure with MTA and an achiral, class 1, non-atropisomeric inhibitor bound 分子名称: (2M)-2-[(4M)-4-{4-(aminomethyl)-1-oxo-8-[(2R)-oxolan-2-yl]-1,2-dihydrophthalazin-6-yl}-1-methyl-1H-pyrazol-5-yl]-1-benzothiophene-3-carbonitrile, 5'-DEOXY-5'-METHYLTHIOADENOSINE, Methylosome protein 50, ... 著者 Gunn, R.J, Thomas, N.C, Lawson, J.D, Ivetac, A, Kulyk, S, Smith, C.R, Marx, M.A. 登録日 2022-04-12 公開日 2022-08-17 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Design and evaluation of achiral, non-atropisomeric 4-(aminomethyl)phthalazin-1(2H)-one derivatives as novel PRMT5/MTA inhibitors. Bioorg.Med.Chem., 71, 2022
8ARI	Cryo-EM structure of human CtBP1/RAI2(303-362) delta(331-341) filament 分子名称: C-terminal-binding protein 1, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, Retinoic acid-induced protein 2 著者 Mullapudi, E, Goradia, N, Wilmanns, M. 登録日 2022-08-16 公開日 2023-08-23 実験手法 ELECTRON MICROSCOPY (3 Å) 主引用文献 Cryo-EM structure of human CtBP1/RAI2(303-362) delta(331-341) filament To Be Published
7QWR	Structure of the ribosome-nascent chain containing an ER signal sequence in complex with NAC 分子名称: 28S rRNA, 5.8S ribosomal RNA, 5S ribosomal RNA, ... 著者 Jomaa, A, Gamerdinger, M, Hsieh, H, Wallisch, A, Chandrasekaran, V, Ulusoy, Z, Scaiola, A, Hegde, R, Shan, S, Ban, N, Deuerling, E. 登録日 2022-01-25 公開日 2022-03-09 最終更新日 2024-07-17 実験手法 ELECTRON MICROSCOPY (2.9 Å) 主引用文献 Mechanism of signal sequence handover from NAC to SRP on ribosomes during ER-protein targeting. Science, 375, 2022
3FZV	Crystal structure of PA01 protein, putative LysR family transcriptional regulator from Pseudomonas aeruginosa 分子名称: Probable transcriptional regulator, SULFATE ION 著者 Knapik, A.A, Tkaczuk, K.L, Chruszcz, M, Wang, S, Zimmerman, M.D, Cymborowski, M, Skarina, T, Kagan, O, Savchenko, A, Edwards, A.M, Joachimiak, A, Bujnicki, J.M, Minor, W, Midwest Center for Structural Genomics (MCSG) 登録日 2009-01-26 公開日 2009-03-10 最終更新日 2022-04-13 実験手法 X-RAY DIFFRACTION (2.71 Å) 主引用文献 Crystal structure of PA01 protein, putative LysR family transcriptional regulator from Pseudomonas aeruginosa To be Published

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