1PXU
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1POW
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1PYM
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1PKP
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1PL7
| Human Sorbitol Dehydrogenase (apo) | 分子名称: | Sorbitol dehydrogenase, ZINC ION | 著者 | Pauly, T.A, Ekstrom, J.L, Beebe, D.A, Chrunyk, B, Cunningham, D, Griffor, M, Kamath, A, Lee, S.E, Madura, R, Mcguire, D, Subashi, T, Wasilko, D, Watts, P, Mylari, B.L, Oates, P.J, Adams, P.D, Rath, V.L. | 登録日 | 2003-06-07 | 公開日 | 2004-02-17 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | X-ray crystallographic and kinetic studies of human sorbitol dehydrogenase. Structure, 11, 2003
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1Q3P
| Crystal structure of the Shank PDZ-ligand complex reveals a class I PDZ interaction and a novel PDZ-PDZ dimerization | 分子名称: | C-terminal hexapeptide from Guanylate kinase-associated protein, Shank1 | 著者 | Im, Y.J, Lee, J.H, Park, S.H, Park, S.J, Rho, S.-H, Kang, G.B, Kim, E, Eom, S.H. | 登録日 | 2003-07-31 | 公開日 | 2004-01-27 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | 主引用文献 | Crystal structure of the Shank PDZ-ligand complex reveals a class I PDZ interaction and a novel PDZ-PDZ dimerization J.Biol.Chem., 278, 2003
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1Q3Q
| Crystal structure of the chaperonin from Thermococcus strain KS-1 (two-point mutant complexed with AMP-PNP) | 分子名称: | MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, Thermosome alpha subunit | 著者 | Shomura, Y, Yoshida, T, Iizuka, R, Maruyama, T, Yohda, M, Miki, K. | 登録日 | 2003-07-31 | 公開日 | 2004-01-27 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Crystal Structures of the Group II Chaperonin from Thermococcus strain KS-1: Steric Hindrance by the Substituted Amino Acid, and Inter-subunit Rearrangement between Two Crystal Forms. J.Mol.Biol., 335, 2004
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1Q5K
| crystal structure of Glycogen synthase kinase 3 in complexed with inhibitor | 分子名称: | Glycogen synthase kinase-3 beta, N-(4-METHOXYBENZYL)-N'-(5-NITRO-1,3-THIAZOL-2-YL)UREA | 著者 | Bhat, R, Xue, Y, Berg, S, Hellberg, S, Ormo, M, Nilsson, Y, Radesater, A.C, Jerning, E, Markgren, P.O, Borgegard, T, Nylof, M, Gimenez-Cassina, A, Hernandez, F, Lucas, J.J, Diaz-Mido, J, Avila, J. | 登録日 | 2003-08-08 | 公開日 | 2004-08-10 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (1.94 Å) | 主引用文献 | Structural insights and biological effects of glycogen synthase kinase 3-specific inhibitor AR-A014418. J.Biol.Chem., 278, 2003
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1PRO
| HIV-1 PROTEASE DIMER COMPLEXED WITH A-98881 | 分子名称: | (5R,6R)-2,4-BIS-(4-HYDROXY-3-METHOXYBENZYL)-1,5-DIBENZYL-3-OXO-6-HYDROXY-1,2,4-TRIAZACYCLOHEPTANE, HIV-1 PROTEASE | 著者 | Park, C.H, Kong, X.P, Dealwis, C.G. | 登録日 | 1995-07-18 | 公開日 | 1996-08-17 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | A novel, picomolar inhibitor of human immunodeficiency virus type 1 protease. J.Med.Chem., 39, 1996
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1PNN
| PEPTIDE NUCLEIC ACID (PNA) COMPLEXED WITH DNA | 分子名称: | DNA (5'-D(GP*AP*AP*GP*AP*AP*GP*AP*G)-3'), PNA (NH2-P(*C*T*C*T*T*C*T*T*C-HIS-GLY-SER-SER-GLY-HIS-C*T*T*C*T*T*C*T*C)-COOH) | 著者 | Betts, L, Veal, J.M. | 登録日 | 1995-10-13 | 公開日 | 1996-03-08 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | A Nucleic Acid Triple Helix Formed by a Peptide Nucleic Acid-DNA Complex Science, 270, 1995
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1PNT
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1PO1
| POLIOVIRUS (TYPE 1, MAHONEY) IN COMPLEX WITH R80633, AN INHIBITOR OF VIRAL REPLICATION | 分子名称: | (METHYLPYRIDAZINE PIPERIDINE BUTYLOXYPHENYL)ETHYLACETATE, MYRISTIC ACID, POLIOVIRUS TYPE 1 MAHONEY | 著者 | Hiremath, C.N, Filman, D.J, Grant, R.A, Hogle, J.M. | 登録日 | 1997-01-08 | 公開日 | 1997-12-03 | 最終更新日 | 2023-08-09 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Ligand-induced conformational changes in poliovirus-antiviral drug complexes. Acta Crystallogr.,Sect.D, 53, 1997
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1POS
| CRYSTAL STRUCTURE OF A NOVEL DISULFIDE-LINKED "TREFOIL" MOTIF FOUND IN A LARGE FAMILY OF PUTATIVE GROWTH FACTORS | 分子名称: | PORCINE PANCREATIC SPASMOLYTIC POLYPEPTIDE | 著者 | De, A, Brown, D, Gorman, M, Carr, M, Sanderson, M.R, Freemont, P.S. | 登録日 | 1993-10-08 | 公開日 | 1994-01-31 | 最終更新日 | 2024-10-23 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Crystal structure of a disulfide-linked "trefoil" motif found in a large family of putative growth factors. Proc.Natl.Acad.Sci.USA, 91, 1994
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1PUF
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1PUP
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1PRG
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1PU2
| Crystal Structure of the K246R Mutant of Aspartate Semialdehyde Dehydrogenase from Haemophilus influenzae | 分子名称: | Aspartate-semialdehyde dehydrogenase | 著者 | Blanco, J, Moore, R.A, Faehnle, C.R, Coe, D.M, Viola, R.E. | 登録日 | 2003-06-23 | 公開日 | 2004-07-27 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (2.06 Å) | 主引用文献 | The role of substrate-binding groups in the mechanism of aspartate-beta-semialdehyde dehydrogenase. Acta Crystallogr.,Sect.D, 60, 2004
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1PTT
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1PUB
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1Q1S
| Mouse Importin alpha- phosphorylated SV40 CN peptide complex | 分子名称: | Importin alpha-2 subunit, Large T antigen | 著者 | Fontes, M.R.M, Teh, T, Toth, G, John, A, Pavo, I, Jans, D.A, Kobe, B. | 登録日 | 2003-07-22 | 公開日 | 2004-03-30 | 最終更新日 | 2024-10-30 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Role of flanking sequences and phosphorylation in the recognition of the simian-virus-40 large T-antigen nuclear localization sequences by importin-alpha Biochem.J., 375, 2003
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1MWE
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1MXH
| Crystal Structure of Substrate Complex of Putative Pteridine Reductase 2 (PTR2) from Trypanosoma cruzi | 分子名称: | DIHYDROFOLIC ACID, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, PTERIDINE REDUCTASE 2 | 著者 | Schormann, N, Pal, B, Senkovich, O, Carson, M, Howard, A, Smith, C, Delucas, L, Chattopadhyay, D. | 登録日 | 2002-10-02 | 公開日 | 2003-10-14 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Crystal structure of Trypanosoma cruzi pteridine reductase 2 in complex with a substrate and an inhibitor. J.Struct.Biol., 152, 2005
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1MRK
| STUDIES ON CRYSTAL STRUCTURES ACTIVE CENTER GEOMETRY AND DEPURINE MECHANISM OF TWO RIBOSOME-INACTIVATING PROTEINS | 分子名称: | (1S)-1-(7-amino-1H-pyrazolo[4,3-d]pyrimidin-3-yl)-1,4-anhydro-D-ribitol, ALPHA-TRICHOSANTHIN | 著者 | Huang, Q, Liu, S, Tang, Y, Jin, S, Wang, Y. | 登録日 | 1994-07-01 | 公開日 | 1995-02-07 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Studies on crystal structures, active-centre geometry and depurinating mechanism of two ribosome-inactivating proteins. Biochem.J., 309, 1995
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1MTO
| Crystal structure of a Phosphofructokinase mutant from Bacillus stearothermophilus bound with fructose-6-phosphate | 分子名称: | 6-O-phosphono-beta-D-fructofuranose, 6-phosphofructokinase | 著者 | Riley-Lovingshimer, M.R, Ronning, D.R, Sacchettini, J.C, Reinhart, G.D. | 登録日 | 2002-09-21 | 公開日 | 2002-12-31 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | Reversible Ligand-Induced Dissociation of a Tryptophan-Shift Mutant of Phosphofructokinase
from Bacillus stearothermophilus Biochemistry, 41, 2002
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1MZC
| Co-Crystal Structure Of Human Farnesyltransferase With Farnesyldiphosphate and Inhibitor Compound 33a | 分子名称: | 2-[3-(3-ETHYL-1-METHYL-2-OXO-AZEPAN-3-YL)-PHENOXY]-4-[1-AMINO-1-(1-METHYL-1H-IMIDIZOL-5-YL)-ETHYL]-BENZONITRILE, FARNESYL DIPHOSPHATE, Protein Farnesyltransferase alpha Subunit, ... | 著者 | deSolms, S.J, Ciccarone, T.M, MacTough, S.C, Shaw, A.W, Buser, C.A, Ellis-Hutchings, M, Fernandes, C, Hamilton, K.A, Huber, H.E, Kohl, N.E, Lobell, R.B, Robinson, R.G, Tsou, N.N, Walsh, E.S, Graham, S.L, Beese, L.S, Taylor, J.S. | 登録日 | 2002-10-07 | 公開日 | 2003-07-08 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Dual Protein Farnesyltransferase-Geranylgeranyltransferase-I Inhibitors as Potential Cancer Chemotherapeutic Agents. J.Med.Chem., 46, 2003
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