1Q5K
crystal structure of Glycogen synthase kinase 3 in complexed with inhibitor
Summary for 1Q5K
| Entry DOI | 10.2210/pdb1q5k/pdb |
| Descriptor | Glycogen synthase kinase-3 beta, N-(4-METHOXYBENZYL)-N'-(5-NITRO-1,3-THIAZOL-2-YL)UREA (3 entities in total) |
| Functional Keywords | kinase-inhibitor complex, transferase |
| Biological source | Homo sapiens (human) |
| Cellular location | Cytoplasm: P49841 |
| Total number of polymer chains | 2 |
| Total formula weight | 92845.41 |
| Authors | Bhat, R.,Xue, Y.,Berg, S.,Hellberg, S.,Ormo, M.,Nilsson, Y.,Radesater, A.C.,Jerning, E.,Markgren, P.O.,Borgegard, T.,Nylof, M.,Gimenez-Cassina, A.,Hernandez, F.,Lucas, J.J.,Diaz-Mido, J.,Avila, J. (deposition date: 2003-08-08, release date: 2004-08-10, Last modification date: 2024-02-14) |
| Primary citation | Bhat, R.,Xue, Y.,Berg, S.,Hellberg, S.,Ormo, M.,Nilsson, Y.,Radesater, A.C.,Jerning, E.,Markgren, P.O.,Borgegard, T.,Nylof, M.,Gimenez-Cassina, A.,Hernandez, F.,Lucas, J.J.,Diaz-Nido, J.,Avila, J. Structural insights and biological effects of glycogen synthase kinase 3-specific inhibitor AR-A014418. J.Biol.Chem., 278:45937-45945, 2003 Cited by PubMed: 12928438DOI: 10.1074/jbc.M306268200 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.94 Å) |
Structure validation
Download full validation report
