PDB: 222624 件ウェブページステータス検索Chemie searchBIRD

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4NQN	Crystal Structure of the bromodomain of human BRD9 in complex with a triazolo-phthalazine ligand 分子名称: 2-chloro-N-[5-(3-methyl[1,2,4]triazolo[3,4-a]phthalazin-6-yl)-2-(morpholin-4-yl)phenyl]benzenesulfonamide, Bromodomain-containing protein 9 著者 Filippakopoulos, P, Picaud, S, Felletar, I, Martin, S, Fedorov, O, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Knapp, S, Structural Genomics Consortium (SGC) 登録日 2013-11-25 公開日 2013-12-18 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.73 Å) 主引用文献 Crystal Structure of the bromodomain of human BRD9 in complex with a triazolo-phthalazine ligand To be Published
3RZK	Duplex Interrogation by a Direct DNA Repair Protein in the Search of Damage 分子名称: 2-OXOGLUTARIC ACID, 5'-D(*CP*TP*GP*TP*CP*TP*(EDA)P*AP*CP*TP*GP*CP*G)-3', 5'-D(*TP*CP*GP*CP*AP*GP*TP*TP*AP*GP*AP*CP*A)-3', ... 著者 Yi, C, Chen, B, Qi, B, Zhang, W, Jia, G, Zhang, L, Li, C, Dinner, A, Yang, C, He, C. 登録日 2011-05-11 公開日 2012-06-06 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.78 Å) 主引用文献 Duplex interrogation by a direct DNA repair protein in search of base damage Nat.Struct.Mol.Biol., 19, 2012
1Z1B	Crystal structure of a lambda integrase dimer bound to a COC' core site 分子名称: 26-MER DNA, 29-MER DNA, 5'-D(*CP*T*CP*GP*TP*TP*CP*AP*GP*CP*TP*TP*TP*TP*TP*T)-3', ... 著者 Biswas, T, Aihara, H, Radman-Livaja, M, Filman, D, Landy, A, Ellenberger, T. 登録日 2005-03-03 公開日 2005-06-28 最終更新日 2022-04-13 実験手法 X-RAY DIFFRACTION (3.8 Å) 主引用文献 A structural basis for allosteric control of DNA recombination by lambda integrase. Nature, 435, 2005
2BJS	Isopenicillin N synthase C-terminal truncation mutant 分子名称: FE (III) ION, ISOPENICILLIN N SYNTHETASE, L-D-(A-AMINOADIPOYL)-L-CYSTEINYL-D-VALINE, ... 著者 McNeill, L.A, Sami, M, Clifton, I.J, Burzlaff, N.I. 登録日 2005-02-07 公開日 2006-03-09 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.3 Å) 主引用文献 Terminally Truncated Isopenicillin N Synthase Generates a Dithioester Product: Evidence for a Thioaldehyde Intermediate during Catalysis and a New Mode of Reaction for Non-Heme Iron Oxidases. Chemistry, 23, 2017
3RZJ	Duplex Interrogation by a Direct DNA Repair Protein in the Search of Damage 分子名称: 2-OXOGLUTARIC ACID, 5'-D(*CP*TP*GP*TP*CP*TP*(ME6)P*AP*CP*TP*GP*CP*G)-3', 5'-D(*TP*CP*GP*CP*AP*GP*TP*GP*AP*GP*AP*CP*A)-3', ... 著者 Yi, C, Chen, B, Qi, B, Zhang, W, Jia, G, Zhang, L, Li, C, Dinner, A, Yang, C, He, C. 登録日 2011-05-11 公開日 2012-06-06 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Duplex interrogation by a direct DNA repair protein in search of base damage Nat.Struct.Mol.Biol., 19, 2012
1C0B	BOVINE PANCREATIC RIBONUCLEASE A DESICCATED FOR 2.5 DAYS 分子名称: RIBONUCLEASE A, SULFATE ION 著者 Bell, J.A. 登録日 1999-07-15 公開日 1999-10-14 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 X-ray crystal structures of a severely desiccated protein Protein Sci., 8, 1999
2P8O	Crystal Structure of a Benzohydroxamic Acid/Vanadate complex bound to chymotrypsin A 分子名称: Chymotrypsin A chain A, Chymotrypsin A chain B, Chymotrypsin A chain C, ... 著者 Moulin, A, Bell, J.H, Pratt, R.F, Ringe, D. 登録日 2007-03-22 公開日 2007-05-08 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Inhibition of chymotrypsin by a complex of ortho-vanadate and benzohydroxamic Acid: structure of the inert complex and its mechanistic interpretation. Biochemistry, 46, 2007
1CJ5	BOVINE BETA-LACTOGLOBULIN A 分子名称: BETA-LACTOGLOBULIN A 著者 Kuwata, K, Hoshino, M, Forge, V, Era, S, Batt, C.A, Goto, Y. 登録日 1999-04-22 公開日 2000-04-26 最終更新日 2023-12-27 実験手法 SOLUTION NMR 主引用文献 Solution structure and dynamics of bovine beta-lactoglobulin A. Protein Sci., 8, 1999
2KPE	Refined structure of Glycophorin A transmembrane segment dimer in DPC micelles 分子名称: Glycophorin-A 著者 Mineev, K.S, Bocharov, E.V, Goncharuk, M.V, Arseniev, A.S, Volynsky, P.E, Efremov, R.G. 登録日 2009-10-13 公開日 2010-09-22 最終更新日 2024-05-01 実験手法 SOLUTION NMR 主引用文献 Dimeric structure of the transmembrane domain of glycophorin a in lipidic and detergent environments. Acta Naturae, 3, 2011
2CKK	High resolution crystal structure of the human kin17 C-terminal domain containing a kow motif 分子名称: ACETATE ION, IODIDE ION, KIN17 著者 le Maire, A, Schiltz, M, Pinon-Lataillade, G, Stura, E, Couprie, J, Gondry, M, Angulo-Mora, J, Zinn-Justin, S. 登録日 2006-04-20 公開日 2006-10-04 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.45 Å) 主引用文献 A Tandem of SH3-Like Domains Participates in RNA Binding in Kin17, a Human Protein Activated in Response to Genotoxics. J.Mol.Biol., 364, 2006
2I8E	Structure of SSO1404, a predicted DNA repair-associated protein from Sulfolobus solfataricus P2 分子名称: Hypothetical protein, IODIDE ION 著者 Wang, S, Zimmerman, M.D, Kudritska, M, Chruszcz, M, Savchenko, A, Edwards, A, Joachimiak, A, Minor, W, Midwest Center for Structural Genomics (MCSG) 登録日 2006-09-01 公開日 2006-09-26 最終更新日 2022-04-13 実験手法 X-RAY DIFFRACTION (1.59 Å) 主引用文献 A novel family of sequence-specific endoribonucleases associated with the clustered regularly interspaced short palindromic repeats. J.Biol.Chem., 283, 2008
1A46	THROMBIN COMPLEXED WITH HIRUGEN AND A BETA-STRAND MIMETIC INHIBITOR 分子名称: (1S,7S)-7-amino-N-[(2R,3S)-7-amino-1-(cyclohexylamino)-2-hydroxy-1-oxoheptan-3-yl]-7-benzyl-8-oxohexahydro-1H-pyrazolo[1,2-a]pyridazine-1-carboxamide, ALPHA-THROMBIN (LARGE SUBUNIT), ALPHA-THROMBIN (SMALL SUBUNIT), ... 著者 St Charles, R, Matthews, J.H, Zhang, E, Tulinsky, A, Kahn, M. 登録日 1998-02-11 公開日 1998-05-27 最終更新日 2023-08-02 実験手法 X-RAY DIFFRACTION (2.12 Å) 主引用文献 Bound structures of novel P3-P1' beta-strand mimetic inhibitors of thrombin. J.Med.Chem., 42, 1999
1A61	THROMBIN COMPLEXED WITH A BETA-MIMETIC THIAZOLE-CONTAINING INHIBITOR 分子名称: (1S,7S)-7-amino-7-benzyl-N-{(1S)-4-carbamimidamido-1-[(S)-hydroxy(1,3-thiazol-2-yl)methyl]butyl}-8-oxohexahydro-1H-pyra zolo[1,2-a]pyridazine-1-carboxamide, ALPHA-THROMBIN (LARGE SUBUNIT), ALPHA-THROMBIN (SMALL SUBUNIT), ... 著者 St Charles, R, Matthews, J.H, Zhang, E, Tulinsky, A, Kahn, M. 登録日 1998-03-05 公開日 1998-06-17 最終更新日 2024-06-05 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Bound structures of novel P3-P1' beta-strand mimetic inhibitors of thrombin. J.Med.Chem., 42, 1999
1RAT	EFFECTS OF TEMPERATURE ON PROTEIN STRUCTURE AND DYNAMICS: X-RAY CRYSTALLOGRAPHIC STUDIES OF THE PROTEIN RIBONUCLEASE-A AT NINE DIFFERENT TEMPERATURES FROM 98 TO 320 K 分子名称: RIBONUCLEASE A 著者 Tiltonjunior, R.F, Dewan, J.C, Petsko, G.A. 登録日 1991-08-13 公開日 1993-07-15 最終更新日 2024-06-05 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Effects of temperature on protein structure and dynamics: X-ray crystallographic studies of the protein ribonuclease-A at nine different temperatures from 98 to 320 K. Biochemistry, 31, 1992
1D6H	CHALONE SYNTHASE (N336A MUTANT COMPLEXED WITH COA) 分子名称: CHALCONE SYNTHASE, COENZYME A, SULFATE ION 著者 Jez, J.M, Ferrer, J.L, Bowman, M.E, Dixon, R.A, Noel, J.P. 登録日 1999-10-13 公開日 2000-02-03 最終更新日 2021-11-03 実験手法 X-RAY DIFFRACTION (2.15 Å) 主引用文献 Dissection of malonyl-coenzyme A decarboxylation from polyketide formation in the reaction mechanism of a plant polyketide synthase. Biochemistry, 39, 2000
1UWF	1.7 A resolution structure of the receptor binding domain of the FimH adhesin from uropathogenic E. coli 分子名称: FIMH PROTEIN, GLYCEROL, butyl alpha-D-mannopyranoside 著者 Bouckaert, J, Berglund, J, Genst, E.D, Cools, L, Hung, C.-S, Wuhrer, M, Zavialov, A, Langermann, S, Hultgren, S, Wyns, L, Oscarson, S, Knight, S.D, De Greve, H. 登録日 2004-02-05 公開日 2005-02-16 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (1.69 Å) 主引用文献 Receptor Binding Studies Disclose a Novel Class of High-Affinity Inhibitors of the Escherichia Coli Fimh Adhesin. Mol.Microbiol., 55, 2005
2KPF	Spatial structure of the dimeric transmembrane domain of glycophorin A in bicelles soluton 分子名称: Glycophorin-A 著者 Mineev, K.S, Bocharov, E.V, Goncharuk, M.V, Arseniev, A.S, Volynsky, P.E, Efremov, R.G. 登録日 2009-10-13 公開日 2010-09-22 最終更新日 2024-05-01 実験手法 SOLUTION NMR 主引用文献 Dimeric structure of the transmembrane domain of glycophorin a in lipidic and detergent environments. Acta Naturae, 3, 2011
1YGC	Short Factor VIIa with a small molecule inhibitor 分子名称: (R)-4-[2-(3-AMINO-BENZENESULFONYLAMINO)-1-(3,5-DIETHOXY-2-FLUOROPHENYL)-2-OXO-ETHYLAMINO]-2-HYDROXY-BENZAMIDINE, CALCIUM ION, Coagulation factor VII, ... 著者 Olivero, A.G, Eigenbrot, C, Goldsmith, R, Robarge, K, Artis, D.R, Flygare, J, Rawson, T, Refino, C, Bunting, S, Kirchhofer, D. 登録日 2005-01-04 公開日 2005-01-18 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 A selective, slow binding inhibitor of factor VIIa binds to a nonstandard active site conformation and attenuates thrombus formation in vivo. J.Biol.Chem., 280, 2005
2OZU	Crystal structure of human MYST histone acetyltransferase 3 in complex with acetylcoenzyme A 分子名称: ACETAMIDE, ACETYL COENZYME *A, Histone acetyltransferase MYST3, ... 著者 Min, J, Wu, H, Dombrovski, L, Bernstein, G, Dong, A, Loppnau, P, Weigelt, J, Sundstrom, M, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Plotnikov, A.N, Structural Genomics Consortium (SGC) 登録日 2007-02-27 公開日 2007-03-13 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 The crystal structure of human MYST histone acetyltransferase 3 in complex with acetylcoenzyme A To be Published
2Q06	Crystal structure of Influenza A Virus H5N1 Nucleoprotein 分子名称: Nucleoprotein 著者 Ng, A.K.L, Zhang, H, Tan, K, Wang, J, Shaw, P.C. 登録日 2007-05-21 公開日 2008-05-27 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (3.3 Å) 主引用文献 Structure of the influenza virus A H5N1 nucleoprotein: implications for RNA binding, oligomerization, and vaccine design. Faseb J., 22, 2008
1C53	S-CLASS CYTOCHROMES C HAVE A VARIETY OF FOLDING PATTERNS: STRUCTURE OF CYTOCHROME C-553 FROM DESULFOVIBRIO VULGARIS DETERMINED BY THE MULTI-WAVELENGTH ANOMALOUS DISPERSION METHOD 分子名称: CYTOCHROME C553, PROTOPORPHYRIN IX CONTAINING FE 著者 Nakagawa, A, Higuchi, Y, Yasuoka, N, Katsube, Y, Yaga, T. 登録日 1991-08-26 公開日 1993-10-31 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 S-class cytochromes c have a variety of folding patterns: structure of cytochrome c-553 from Desulfovibrio vulgaris determined by the multi-wavelength anomalous dispersion method. J.Biochem.(Tokyo), 108, 1990
2B29	N-terminal domain of the RPA70 subunit of human replication protein A. 分子名称: Replication protein A 70 kDa DNA-binding subunit 著者 Bochkareva, E, Kaustov, L, Ayed, A, Okorokov, A, Milner, J, Arrowsmith, C.H, Bochkarev, A. 登録日 2005-09-18 公開日 2005-10-04 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Single-stranded DNA mimicry in the p53 transactivation domain interaction with replication protein A. Proc.Natl.Acad.Sci.Usa, 102, 2005
1SS1	STAPHYLOCOCCAL PROTEIN A, B-DOMAIN, Y15W MUTANT, NMR, 25 STRUCTURES 分子名称: Immunoglobulin G binding protein A 著者 Sato, S, Religa, T.L, Daggett, V, Fersht, A.R. 登録日 2004-03-23 公開日 2004-04-06 最終更新日 2024-05-22 実験手法 SOLUTION NMR 主引用文献 From The Cover: Testing protein-folding simulations by experiment: B domain of protein A. Proc.Natl.Acad.Sci.USA, 101, 2004
2C9W	CRYSTAL STRUCTURE OF SOCS-2 IN COMPLEX WITH ELONGIN-B AND ELONGIN-C AT 1.9A RESOLUTION 分子名称: NICKEL (II) ION, SULFATE ION, SUPPRESSOR OF CYTOKINE SIGNALING 2, ... 著者 Debreczeni, J.E, Bullock, A, Amos, A, Savitsky, P, Barr, A, Burgess, N, Sundstrom, M, Weigelt, J, Arrowsmith, C, Edwards, A, Knapp, S. 登録日 2005-12-14 公開日 2006-02-22 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Crystal structure of the SOCS2-elongin C-elongin B complex defines a prototypical SOCS box ubiquitin ligase. Proc. Natl. Acad. Sci. U.S.A., 103, 2006
2L0J	Solid State NMR structure of the M2 proton channel from Influenza A Virus in hydrated lipid bilayer 分子名称: Matrix protein 2 著者 Sharma, M, Yi, M, Dong, H, Qin, H, Peterson, E, Busath, D.D, Zhou, H.X, Cross, T.A. 登録日 2010-07-08 公開日 2010-11-03 最終更新日 2024-05-01 実験手法 SOLID-STATE NMR 主引用文献 Insight into the mechanism of the influenza a proton channel from a structure in a lipid bilayer. Science, 330, 2010

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