2BJS

Isopenicillin N synthase C-terminal truncation mutant

Summary for 2BJS

Entry DOI	10.2210/pdb2bjs/pdb
Related	1BK0 1BLZ 1HB1 1HB2 1HB3 1HB4 1IPS 1OBN 1OC1 1ODM 1ODN 1QIQ 1QJE 1QJF 1UZW 1W03 1W04 1W05 1W06 1W3V 1W3X 2BU9
Descriptor	ISOPENICILLIN N SYNTHETASE, FE (III) ION, L-D-(A-AMINOADIPOYL)-L-CYSTEINYL-D-VALINE, ... (6 entities in total)
Functional Keywords	oxidoreductase, antibiotic biosynthesis, b-lactam antibiotic, iron, oxygenase, penicillin biosynthesis, vitamin c
Biological source	EMERICELLA NIDULANS
Total number of polymer chains	1
Total formula weight	37847.04
Authors	McNeill, L.A.,Sami, M.,Clifton, I.J.,Burzlaff, N.I. (deposition date: 2005-02-07, release date: 2006-03-09, Last modification date: 2023-12-13)
Primary citation	McNeill, L.A.,Brown, T.J.N.,Sami, M.,Clifton, I.J.,Burzlaff, N.I.,Claridge, T.D.W.,Adlington, R.M.,Baldwin, J.E.,Rutledge, P.J.,Schofield, C.J. Terminally Truncated Isopenicillin N Synthase Generates a Dithioester Product: Evidence for a Thioaldehyde Intermediate during Catalysis and a New Mode of Reaction for Non-Heme Iron Oxidases. Chemistry, 23:12815-12824, 2017 Cited by PubMed: 28703303 DOI: 10.1002/chem.201701592 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.3 Å)

Structure validation