2PBG
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8V0N
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4H8E
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8V0R
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3I4B
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![BU of 3i4b by Molmil](/molmil-images/mine/3i4b) | Crystal structure of GSK3b in complex with a pyrimidylpyrrole inhibitor | 分子名称: | Glycogen synthase kinase-3 beta, N-[(1S)-2-hydroxy-1-phenylethyl]-4-[5-methyl-2-(phenylamino)pyrimidin-4-yl]-1H-pyrrole-2-carboxamide | 著者 | Ter Haar, E. | 登録日 | 2009-07-01 | 公開日 | 2010-01-12 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Structure-guided design of potent and selective pyrimidylpyrrole inhibitors of extracellular signal-regulated kinase (ERK) using conformational control. J.Med.Chem., 52, 2009
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3HNP
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![BU of 3hnp by Molmil](/molmil-images/mine/3hnp) | Crystal Structure of an Oxidoreductase from Bacillus cereus. Northeast Structural Genomics Consortium target id BcR251 | 分子名称: | Oxidoreductase | 著者 | Seetharaman, J, Su, M, Sahdev, S, Janjua, H, Xiao, R, Ciccosanti, C, Foote, E.L, Acton, T.B, Rost, B, Montelione, G.T, Tong, L, Hunt, J.F, Northeast Structural Genomics Consortium (NESG) | 登録日 | 2009-05-31 | 公開日 | 2009-06-30 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Crystal Structure of an Oxidoreductase from Bacillus cereus. Northeast Structural Genomics Consortium target id BcR251 TO BE PUBLISHED
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2B3V
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![BU of 2b3v by Molmil](/molmil-images/mine/2b3v) | Spermine spermidine acetyltransferase in complex with acetylcoa, K26R mutant | 分子名称: | ACETYL COENZYME *A, Diamine acetyltransferase 1 | 著者 | Bewley, M.C, Graziano, V, Jiang, J.S, Matz, E, Studier, F.W, Pegg, A.P, Coleman, C.S, Flanagan, J.M, Burley, S.K, New York SGX Research Center for Structural Genomics (NYSGXRC) | 登録日 | 2005-09-21 | 公開日 | 2006-01-17 | 最終更新日 | 2021-02-03 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Structures of wild-type and mutant human spermidine/spermine N1-acetyltransferase, a potential therapeutic drug target. Proc.Natl.Acad.Sci.USA, 103, 2006
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6JZI
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![BU of 6jzi by Molmil](/molmil-images/mine/6jzi) | Structure of hen egg-white lysozyme obtained from SFX experiments under atmospheric pressure | 分子名称: | CHLORIDE ION, Lysozyme C, SODIUM ION | 著者 | Nango, E, Sugahara, M, Nakane, T, Tanaka, T, Iwata, S. | 登録日 | 2019-05-02 | 公開日 | 2019-10-30 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | High-viscosity sample-injection device for serial femtosecond crystallography at atmospheric pressure. J.Appl.Crystallogr., 52, 2019
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6GU6
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![BU of 6gu6 by Molmil](/molmil-images/mine/6gu6) | CDK1/Cks2 in complex with Dinaciclib | 分子名称: | 3-[({3-ethyl-5-[(2S)-2-(2-hydroxyethyl)piperidin-1-yl]pyrazolo[1,5-a]pyrimidin-7-yl}amino)methyl]-1-hydroxypyridinium, Cyclin-dependent kinase 1, Cyclin-dependent kinases regulatory subunit 2 | 著者 | Wood, D.J, Korolchuk, S, Tatum, N.J, Wang, L.Z, Endicott, J.A, Noble, M.E.M, Martin, M.P. | 登録日 | 2018-06-19 | 公開日 | 2018-12-05 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.33 Å) | 主引用文献 | Differences in the Conformational Energy Landscape of CDK1 and CDK2 Suggest a Mechanism for Achieving Selective CDK Inhibition. Cell Chem Biol, 26, 2019
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2VDT
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![BU of 2vdt by Molmil](/molmil-images/mine/2vdt) | Crystallographic structure of Levansucrase from Bacillus subtilis mutant S164A | 分子名称: | CALCIUM ION, LEVANSUCRASE | 著者 | Ortiz-Soto, M.E, Rivera, M, Rudino-Pinera, E, Olvera, C, Lopez-Munguia, A. | 登録日 | 2007-10-11 | 公開日 | 2008-07-15 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | Selected Mutations in Bacillus Subtilis Levansucrase Semi-Conserved Regions Affecting its Biochemical Properties Protein Eng.Des.Sel., 21, 2008
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1GNH
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![BU of 1gnh by Molmil](/molmil-images/mine/1gnh) | HUMAN C-REACTIVE PROTEIN | 分子名称: | C-REACTIVE PROTEIN, CALCIUM ION | 著者 | Shrive, A.K, Cheetham, G.M.T, Holden, D, Myles, D.A, Turnell, W.G, Volanakis, J.E, Pepys, M.B, Bloomer, A.C, Greenhough, T.J. | 登録日 | 1996-03-01 | 公開日 | 1997-01-27 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Three dimensional structure of human C-reactive protein. Nat.Struct.Biol., 3, 1996
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8UKW
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8V0Q
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4I0X
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![BU of 4i0x by Molmil](/molmil-images/mine/4i0x) | Crystal structure of the Mycobacterum abscessus EsxEF (Mab_3112-Mab_3113) complex | 分子名称: | BETA-MERCAPTOETHANOL, ESAT-6-like protein MAB_3112, ESAT-6-like protein MAB_3113, ... | 著者 | Arbing, M.A, Chan, S, Lu, J, Kuo, E, Harris, L, Eisenberg, D, Integrated Center for Structure and Function Innovation (ISFI), TB Structural Genomics Consortium (TBSGC) | 登録日 | 2012-11-19 | 公開日 | 2013-01-16 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.956 Å) | 主引用文献 | Heterologous expression of mycobacterial Esx complexes in Escherichia coli for structural studies is facilitated by the use of maltose binding protein fusions. Plos One, 8, 2013
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3E1J
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![BU of 3e1j by Molmil](/molmil-images/mine/3e1j) | Crystal structure of E. coli Bacterioferritin (BFR) with an unoccupied ferroxidase centre (APO-BFR). | 分子名称: | Bacterioferritin, PROTOPORPHYRIN IX CONTAINING FE, SULFATE ION | 著者 | Crow, A, Lawson, T, Lewin, A, Moore, G.R, Le Brun, N. | 登録日 | 2008-08-04 | 公開日 | 2009-05-05 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Structural basis for iron mineralization by bacterioferritin J.Am.Chem.Soc., 131, 2009
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8V0U
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4R1T
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![BU of 4r1t by Molmil](/molmil-images/mine/4r1t) | Crystal structure of Petunia hydrida cinnamoyl-CoA reductase | 分子名称: | cinnamoyl CoA reductase, molecular iodine | 著者 | Noel, J.P, Louie, G.V, Bowman, M.E, Bomati, E.K. | 登録日 | 2014-08-07 | 公開日 | 2014-10-01 | 最終更新日 | 2014-11-12 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Structural Studies of Cinnamoyl-CoA Reductase and Cinnamyl-Alcohol Dehydrogenase, Key Enzymes of Monolignol Biosynthesis. Plant Cell, 26, 2014
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2YPQ
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![BU of 2ypq by Molmil](/molmil-images/mine/2ypq) | 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase with tryptophan and tyrosine bound | 分子名称: | CHLORIDE ION, GLYCEROL, MANGANESE (II) ION, ... | 著者 | Blackmore, N.J, Reichau, S, Jiao, W, Hutton, R.D, Baker, E.N, Jameson, G.B, Parker, E.J. | 登録日 | 2012-10-31 | 公開日 | 2013-01-09 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.76 Å) | 主引用文献 | Three Sites and You are Out: Ternary Synergistic Allostery Controls Aromatic Aminoacid Biosynthesis in Mycobacterium Tuberculosis. J.Mol.Biol., 425, 2013
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2WXV
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![BU of 2wxv by Molmil](/molmil-images/mine/2wxv) | Structure of CDK2-CYCLIN A with a Pyrazolo(4,3-h) quinazoline-3- carboxamide inhibitor | 分子名称: | CELL DIVISION PROTEIN KINASE 2, CYCLIN-A2, N,1-DIMETHYL-8-{[1-(METHYLSULFONYL)PIPERIDIN-4-YL]AMINO}-1H-PYRAZOLO[4,3-H]QUINAZOLINE-3-CARBOXAMIDE, ... | 著者 | Traquandi, G, Ciomei, M, Ballinari, D, Casale, E, Colombo, N, Croci, V, Fiorentini, F, Isacchi, A, Longo, A, Mercurio, C, Panzeri, A, Pastori, W, Pevarello, P, Volpi, D, Roussel, P, Vulpetti, A, Brasca, M.G. | 登録日 | 2009-11-10 | 公開日 | 2010-02-23 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Identification of Potent Pyrazolo[4,3-H]Quinazoline-3-Carboxamides as Multi-Cyclin-Dependent Kinase Inhibitors. J.Med.Chem., 53, 2010
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4A9X
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![BU of 4a9x by Molmil](/molmil-images/mine/4a9x) | Pseudomonas fluorescens PhoX in complex with the substrate analogue AppCp | 分子名称: | 1,2-ETHANEDIOL, CALCIUM ION, MU-OXO-DIIRON, ... | 著者 | Yong, S.C, Roversi, P, Lillington, J.E.D, Zeldin, O.B, Garman, E.F, Lea, S.M, Berks, B.C. | 登録日 | 2011-11-29 | 公開日 | 2012-12-05 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.79 Å) | 主引用文献 | A Complex Iron-Calcium Cofactor Catalyzing Phosphotransfer Chemistry Science, 345, 2014
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4HTK
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![BU of 4htk by Molmil](/molmil-images/mine/4htk) | Mitigation of X-ray damage in macromolecular crystallography by submicrometer line focusing; total dose 2.17 x 10e+12 X-ray photons | 分子名称: | 1,2-ETHANEDIOL, CHLORIDE ION, Lysozyme C, ... | 著者 | Duke, N.E.C, Finfrock, Y.Z, Stern, E.A, Alkire, R.W, Lazarski, K, Joachimiak, A. | 登録日 | 2012-11-01 | 公開日 | 2013-05-15 | 最終更新日 | 2013-08-28 | 実験手法 | X-RAY DIFFRACTION (1.2 Å) | 主引用文献 | Mitigation of X-ray damage in macromolecular crystallography by submicrometre line focusing. Acta Crystallogr.,Sect.D, 69, 2013
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4RTF
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![BU of 4rtf by Molmil](/molmil-images/mine/4rtf) | Crystal structure of molecular chaperone DnaK from Mycobacterium tuberculosis H37Rv | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, Chaperone protein DnaK, TETRAETHYLENE GLYCOL | 著者 | Filippova, E.V, Minasov, G, Kiryukhina, O, Endres, M, Babnigg, G, Rubin, E, Sacchettini, J, Joachimiak, A, Anderson, W.F, Midwest Center for Structural Genomics (MCSG), Structures of Mtb Proteins Conferring Susceptibility to Known Mtb Inhibitors (MTBI) | 登録日 | 2014-11-14 | 公開日 | 2014-12-10 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.77 Å) | 主引用文献 | Crystal structure of molecular chaperone DnaK from Mycobacterium tuberculosis H37Rv To be Published
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3HXU
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![BU of 3hxu by Molmil](/molmil-images/mine/3hxu) | Crystal Structure of catalytic fragment of E. coli AlaRS in complex with AlaSA | 分子名称: | '5'-O-(N-(L-ALANYL)-SULFAMOYL)ADENOSINE, 2-HYDROXYETHYL DISULFIDE, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ... | 著者 | Guo, M, Yang, X.-L, Schimmel, P. | 登録日 | 2009-06-22 | 公開日 | 2009-12-15 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Paradox of mistranslation of serine for alanine caused by AlaRS recognition dilemma. Nature, 462, 2009
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3HPA
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![BU of 3hpa by Molmil](/molmil-images/mine/3hpa) | Crystal structure of an amidohydrolase gi:44264246 from an evironmental sample of sargasso sea | 分子名称: | AMIDOHYDROLASE, ZINC ION | 著者 | Fedorov, A.A, Fedorov, E.V, Toro, R, Raushel, F.M, Burley, S.K, Almo, S.C, New York SGX Research Center for Structural Genomics (NYSGXRC) | 登録日 | 2009-06-03 | 公開日 | 2009-06-16 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | The hunt for 8-oxoguanine deaminase. J.Am.Chem.Soc., 132, 2010
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2X9O
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![BU of 2x9o by Molmil](/molmil-images/mine/2x9o) | STRUCTURE OF 15, 16- DIHYDROBILIVERDIN:FERREDOXIN OXIDOREDUCTASE (PebA) | 分子名称: | 15,16-DIHYDROBILIVERDIN-FERREDOXIN OXIDOREDUCTASE, BILIVERDINE IX ALPHA | 著者 | Busch, A.W.U, Frankenberg-Dinkel, N, Hofmann, E. | 登録日 | 2010-03-23 | 公開日 | 2011-03-30 | 最終更新日 | 2013-11-13 | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | 主引用文献 | Structural and Mechanistic Insight Into the Ferredoxin-Mediated Two-Electron Reduction of Bilins. Biochem.J., 439, 2011
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