4YWU
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![BU of 4ywu by Molmil](/molmil-images/mine/4ywu) | Structural insight into the substrate inhibition mechanism of NADP+-dependent succinic semialdehyde dehydrogenase from Streptococcus pyogenes | 分子名称: | 4-oxobutanoic acid, SULFATE ION, Succinic semialdehyde dehydrogenase | 著者 | Jang, E.H, Park, S.A, Chi, Y.M, Lee, K.S. | 登録日 | 2015-03-21 | 公開日 | 2015-05-06 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Structural insight into the substrate inhibition mechanism of NADP(+)-dependent succinic semialdehyde dehydrogenase from Streptococcus pyogenes. Biochem.Biophys.Res.Commun., 461, 2015
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4Y8P
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3OUH
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![BU of 3ouh by Molmil](/molmil-images/mine/3ouh) | PHD2-R127 with JNJ41536014 | 分子名称: | 1-(5-chloro-6-fluoro-1H-benzimidazol-2-yl)-1H-pyrazole-4-carboxylic acid, Egl nine homolog 1, FE (II) ION, ... | 著者 | Kim, H, Clark, R. | 登録日 | 2010-09-14 | 公開日 | 2010-12-01 | 最終更新日 | 2018-04-18 | 実験手法 | X-RAY DIFFRACTION (2.51 Å) | 主引用文献 | Benzimidazole-2-pyrazole HIF Prolyl 4-Hydroxylase Inhibitors as Oral Erythropoietin Secretagogues. ACS Med Chem Lett, 1, 2010
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4Y9Y
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![BU of 4y9y by Molmil](/molmil-images/mine/4y9y) | Yeast 20S proteasome beta2-H116E mutant | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, MAGNESIUM ION, Proteasome subunit alpha type-1, ... | 著者 | Huber, E.M, Groll, M. | 登録日 | 2015-02-17 | 公開日 | 2015-06-17 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Systematic Analyses of Substrate Preferences of 20S Proteasomes Using Peptidic Epoxyketone Inhibitors. J.Am.Chem.Soc., 137, 2015
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1GN9
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![BU of 1gn9 by Molmil](/molmil-images/mine/1gn9) | Hybrid Cluster Protein from Desulfovibrio desulfuricans ATCC 27774 X-ray structure at 2.6A resolution using synchrotron radiation at a wavelength of 1.722A | 分子名称: | HYBRID CLUSTER PROTEIN, IRON/SULFUR CLUSTER, IRON/SULFUR/OXYGEN HYBRID CLUSTER | 著者 | Macedo, S, Mitchell, E.P, Romao, C.V, Cooper, S.J, Coelho, R, Liu, M.Y, Xavier, A.V, Legall, J, Bailey, S, Garner, D.C, Hagen, W.R, Teixeira, M, Carrondo, M.A, Lindley, P. | 登録日 | 2001-10-04 | 公開日 | 2002-04-11 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Hybrid Cluster Proteins (Hcps) from Desulfovibrio Desulfuricans Atcc 27774 and Desulfovibrio Vulgaris (Hildenborough): X-Ray Structures at 1.25 A Resolution Using Synchrotron Radiation. J.Biol.Inorg.Chem., 7, 2002
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4LHV
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![BU of 4lhv by Molmil](/molmil-images/mine/4lhv) | Crystal structure of Rab8 in its inactive GDP-bound form | 分子名称: | GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Ras-related protein Rab-8A | 著者 | Guo, Z, Hou, X.M, Goody, R.S, Itzen, A. | 登録日 | 2013-07-01 | 公開日 | 2013-10-09 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Intermediates in the Guanine Nucleotide Exchange Reaction of Rab8 Protein Catalyzed by Guanine Nucleotide Exchange Factors Rabin8 and GRAB. J.Biol.Chem., 288, 2013
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5IDD
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![BU of 5idd by Molmil](/molmil-images/mine/5idd) | Comment on S. W. M. Tanley and J. R. Helliwell Structural dynamics of cisplatin binding to histidine in a protein Struct. Dyn. 1, 034701 (2014) regarding the refinement of 4mwk, 4mwm, 4mwn and 4oxe and the method we have adopted. | 分子名称: | ACETATE ION, DIMETHYL SULFOXIDE, Lysozyme C, ... | 著者 | Tanley, S.W.M, Helliwell, J.R. | 登録日 | 2016-02-24 | 公開日 | 2016-05-18 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.13 Å) | 主引用文献 | Comment on "Structural dynamics of cisplatin binding to histidine in a protein" [Struct. Dyn. 1, 034701 (2014)]. Struct Dyn., 3, 2016
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1FWC
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5IEL
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![BU of 5iel by Molmil](/molmil-images/mine/5iel) | Structure of Lysozyme labeled with fluorescein isothiocyanate (FITC) at 1.15 Angstroms resolution | 分子名称: | 2-(6-hydroxy-3-oxo-3H-xanthen-9-yl)-5-[(E)-(sulfanylmethylidene)amino]benzoic acid, Lysozyme C | 著者 | Kachalova, G.S, Vlaskina, A.V, Popov, A.P, Simanovskaia, A.A, Krukova, M.V, Lipkin, A.V. | 登録日 | 2016-02-25 | 公開日 | 2017-03-08 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.15 Å) | 主引用文献 | Structure of Lysozyme labeled with fluorescein isothiocyanate (FITC) at 1.15 Angstroms resolution To Be Published
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1GEU
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1FWI
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5II3
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![BU of 5ii3 by Molmil](/molmil-images/mine/5ii3) | The X-ray structure of the adduct formed in the reaction between hen egg white lysozyme and compound 3, a platin(II) compound containing a O, S bidentate ligand | 分子名称: | CHLORIDE ION, DIMETHYL SULFOXIDE, Lysozyme C, ... | 著者 | Ferraro, G, Merlino, A. | 登録日 | 2016-03-01 | 公開日 | 2016-12-07 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.78 Å) | 主引用文献 | Platinum(ii) O,S complexes as potential metallodrugs against Cisplatin resistance. Dalton Trans, 45, 2016
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1SG5
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3P6M
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![BU of 3p6m by Molmil](/molmil-images/mine/3p6m) | Crystal Structure of Cytochrome P450cam crystallized in the presence of a tethered substrate analog AdaC1-C8-Dans | 分子名称: | ADAMANTANE-1-CARBOXYLIC ACID-5-DIMETHYLAMINO-NAPHTHALENE-1-SULFONYLAMINO-OCTYL-AMIDE, Camphor 5-monooxygenase, POTASSIUM ION, ... | 著者 | Lee, Y.-T, Wilson, R.F, Glazer, E.C, Goodin, D.B. | 登録日 | 2010-10-11 | 公開日 | 2010-11-17 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Crystal Structure of Cytochrome P450cam crystallized in the presence of a tethered substrate analog AdaC1-C8-Dans To be Published
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5IKH
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![BU of 5ikh by Molmil](/molmil-images/mine/5ikh) | Tobacco 5-epi-aristolochene synthase M4 mutant with (-)-premnaspirodiene | 分子名称: | (2R,5S,10R)-6,10-dimethyl-2-(prop-1-en-2-yl)spiro[4.5]dec-6-ene, 5-epi-aristolochene synthase, MAGNESIUM ION | 著者 | Koo, H.J, O'Maille, P.E, Louie, G.V, Bowman, M, Noel, J.P. | 登録日 | 2016-03-03 | 公開日 | 2016-10-05 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Biosynthetic potential of sesquiterpene synthases: product profiles of Egyptian Henbane premnaspirodiene synthase and related mutants. J.Antibiot., 69, 2016
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1RA5
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![BU of 1ra5 by Molmil](/molmil-images/mine/1ra5) | Bacterial cytosine deaminase D314A mutant bound to 5-fluoro-4-(S)-hydroxyl-3,4-dihydropyrimidine. | 分子名称: | (4S)-5-FLUORO-4-HYDROXY-3,4-DIHYDROPYRIMIDIN-2(1H)-ONE, Cytosine deaminase, FE (III) ION, ... | 著者 | Mahan, S.D, Ireton, G.C, Stoddard, B.L, Black, M.E. | 登録日 | 2003-10-31 | 公開日 | 2004-10-05 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | 主引用文献 | Random mutagenesis and selection of Escherichia coli cytosine deaminase for cancer gene therapy. Protein Eng.Des.Sel., 17, 2004
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1GD1
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1GL3
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![BU of 1gl3 by Molmil](/molmil-images/mine/1gl3) | ASPARTATE BETA-SEMIALDEHYDE DEHYDROGENASE IN COMPLEX WITH NADP AND SUBSTRATE ANALOGUE S-METHYL CYSTEINE SULFOXIDE | 分子名称: | ASPARTATE-SEMIALDEHYDE DEHYDROGENASE, CYSTEINE, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | 著者 | Hadfield, A.T, Kryger, G, Ouyang, J, Ringe, D, Petsko, G.A, Viola, R.E. | 登録日 | 2001-08-23 | 公開日 | 2001-11-01 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Active Site Analysis of the Potential Antimicrobial Target Aspartate Semialdehyde Dehydrogenase. Biochemistry, 40, 2001
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5INH
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![BU of 5inh by Molmil](/molmil-images/mine/5inh) | Crystal structure of Autotaxin/ENPP2 with a covalent fragment | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ACETATE ION, ... | 著者 | Klein, M.G, Tjhen, R. | 登録日 | 2016-03-07 | 公開日 | 2017-03-15 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (1.84 Å) | 主引用文献 | Repurposing Suzuki Coupling Reagents as a Directed Fragment Library Targeting Serine Hydrolases and Related Enzymes. J. Med. Chem., 60, 2017
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4YSF
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1GKQ
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4YSX
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![BU of 4ysx by Molmil](/molmil-images/mine/4ysx) | Crystal structure of Mitochondrial rhodoquinol-fumarate reductase from Ascaris suum with the specific inhibitor NN23 | 分子名称: | Cytochrome b-large subunit, FE2/S2 (INORGANIC) CLUSTER, FE3-S4 CLUSTER, ... | 著者 | Harada, S, Shiba, T, Sato, D, Yamamoto, A, Nagahama, M, Yone, A, Inaoka, D.K, Sakamoto, K, Inoue, M, Honma, T, Kita, K. | 登録日 | 2015-03-17 | 公開日 | 2015-08-05 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | 主引用文献 | Structural Insights into the Molecular Design of Flutolanil Derivatives Targeted for Fumarate Respiration of Parasite Mitochondria Int J Mol Sci, 16, 2015
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5IOV
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![BU of 5iov by Molmil](/molmil-images/mine/5iov) | Cryo-EM structure of GluN1/GluN2B NMDA receptor in the glutamate/glycine/Ro25-6981-bound conformation | 分子名称: | 4-[(1R,2S)-3-(4-benzylpiperidin-1-yl)-1-hydroxy-2-methylpropyl]phenol, GLUTAMIC ACID, GLYCINE, ... | 著者 | Zhu, S, Stein, A.R, Yoshioka, C, Lee, C.H, Goehring, A, Mchaourab, S.H, Gouaux, E. | 登録日 | 2016-03-09 | 公開日 | 2016-04-20 | 最終更新日 | 2024-03-06 | 実験手法 | ELECTRON MICROSCOPY (7.5 Å) | 主引用文献 | Mechanism of NMDA Receptor Inhibition and Activation. Cell, 165, 2016
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5IPV
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![BU of 5ipv by Molmil](/molmil-images/mine/5ipv) | Cryo-EM structure of GluN1/GluN2B NMDA receptor in the DCKA/D-APV-bound conformation, state 1 | 分子名称: | Ionotropic glutamate receptor subunit NR2B, N-methyl-D-aspartate receptor subunit NR1-8a | 著者 | Zhu, S, Stein, A.R, Yoshioka, C, Lee, C.H, Goehring, A, McHaourab, S.H, Gouaux, E. | 登録日 | 2016-03-10 | 公開日 | 2016-04-20 | 最終更新日 | 2024-03-06 | 実験手法 | ELECTRON MICROSCOPY (9.25 Å) | 主引用文献 | Mechanism of NMDA Receptor Inhibition and Activation. Cell, 165, 2016
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1R31
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![BU of 1r31 by Molmil](/molmil-images/mine/1r31) | HMG-CoA reductase from Pseudomonas mevalonii complexed with HMG-CoA | 分子名称: | (R)-MEVALONATE, 3-hydroxy-3-methylglutaryl-coenzyme A reductase, COENZYME A, ... | 著者 | Watson, J.M, Steussy, C.N, Burgner, J.W, Lawrence, C.M, Tabernero, L, Rodwell, V.W, Stauffacher, C.V. | 登録日 | 2003-09-30 | 公開日 | 2003-10-14 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Structural Investigations of the Basis for Stereoselectivity from the Binary Complex of HMG-CoA Reductase. To be Published
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