PDB: 19129 件ウェブページステータス検索Chemie searchBIRD

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5LPM	Crystal structure of the bromodomain of human Ep300 bound to the inhibitor XDM3d 分子名称: ACETATE ION, Histone acetyltransferase p300, ~{N}-[(1~{S},2~{S})-7-chloranyl-2-oxidanyl-1,2,3,4-tetrahydronaphthalen-1-yl]-4-ethanoyl-3-ethyl-5-methyl-1~{H}-pyrrole -2-carboxamide 著者 Huegle, M, Wohlwend, D, Gerhardt, S. 登録日 2016-08-13 公開日 2017-08-16 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Beyond the BET Family: Targeting CBP/p300 with 4-Acyl Pyrroles. Angew. Chem. Int. Ed. Engl., 56, 2017
5LUK	Structure of a double variant of cutinase 2 from Thermobifida cellulosilytica 分子名称: CHLORIDE ION, Cutinase 2, MAGNESIUM ION 著者 Hromic, A, Lyskowski, A, Gruber, K. 登録日 2016-09-09 公開日 2017-07-12 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.45 Å) 主引用文献 Small cause, large effect: Structural characterization of cutinases from Thermobifida cellulosilytica. Biotechnol. Bioeng., 114, 2017
5LUJ	Structure of cutinase 2 from Thermobifida cellulosilytica 分子名称: CHLORIDE ION, Cutinase 2 著者 Hromic, A, Lyskowski, A, Gruber, K. 登録日 2016-09-08 公開日 2017-07-12 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Small cause, large effect: Structural characterization of cutinases from Thermobifida cellulosilytica. Biotechnol. Bioeng., 114, 2017
5LPK	Crystal structure of the bromodomain of human EP300 bound to the inhibitor XDM1 分子名称: 1,2-ETHANEDIOL, Histone acetyltransferase p300, SULFATE ION, ... 著者 Huegle, M, Wohlwend, D. 登録日 2016-08-13 公開日 2017-08-16 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Beyond the BET Family: Targeting CBP/p300 with 4-Acyl Pyrroles. Angew. Chem. Int. Ed. Engl., 56, 2017
5L3R	Structure of the GTPase heterodimer of chloroplast SRP54 and FtsY from Arabidopsis thaliana 分子名称: Cell division protein FtsY homolog, chloroplastic, GLYCEROL, ... 著者 Bange, G, Kribelbauer, J, Wild, K, Sinning, I. 登録日 2016-05-24 公開日 2016-06-08 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Structural Basis for Conserved Regulation and Adaptation of the Signal Recognition Particle Targeting Complex. J.Mol.Biol., 428, 2016
5L3Q	Structure of the GTPase heterodimer of human SRP54 and SRalpha 分子名称: ADENOSINE MONOPHOSPHATE, GLYCEROL, MAGNESIUM ION, ... 著者 Wild, K, Segnitz, B, Sinning, I. 登録日 2016-05-24 公開日 2016-06-08 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 Structural Basis for Conserved Regulation and Adaptation of the Signal Recognition Particle Targeting Complex. J.Mol.Biol., 428, 2016
5ZNX	Crystal structure of CM14-treated HlyU from Vibrio vulnificus 分子名称: Transcriptional activator 著者 Park, N, Kim, S, Jo, I, Ahn, J, Hong, S, Jeong, S, Baek, Y. 登録日 2018-04-11 公開日 2019-04-10 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.114 Å) 主引用文献 Small-molecule inhibitor of HlyU attenuates virulence of Vibrio species. Sci Rep, 9, 2019
5KSI	Crystal structure of deoxygenated hemoglobin in complex with sphingosine phosphate and 2,3-Bisphosphoglycerate 分子名称: (2R)-2,3-diphosphoglyceric acid, (2S,3R,4E)-2-amino-3-hydroxyoctadec-4-en-1-yl dihydrogen phosphate, Hemoglobin subunit alpha, ... 著者 Ahmed, M.H, Safo, M.K, Xia, Y. 登録日 2016-07-08 公開日 2017-07-26 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Structural and Functional Insight of Sphingosine 1-Phosphate-Mediated Pathogenic Metabolic Reprogramming in Sickle Cell Disease. Sci Rep, 7, 2017
5X90	Structure of DotL(656-783)-IcmS-IcmW-LvgA derived from Legionella pneumophila 分子名称: Hypothetical virulence protein, IcmO (DotL), IcmS, ... 著者 Kim, H, Kwak, M.J, Kim, J.D, Kim, Y.G, Oh, B.H. 登録日 2017-03-04 公開日 2017-06-14 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Architecture of the type IV coupling protein complex of Legionella pneumophila Nat Microbiol, 2, 2017
5XAH	Crystal structure of human Importin4 分子名称: Importin-4 著者 Song, J.J, Yoon, J. 登録日 2017-03-13 公開日 2018-02-14 最終更新日 2018-04-11 実験手法 X-RAY DIFFRACTION (3.004 Å) 主引用文献 Integrative Structural Investigation on the Architecture of Human Importin4_Histone H3/H4_Asf1a Complex and Its Histone H3 Tail Binding J. Mol. Biol., 430, 2018
5X5U	Crystal structure of alpha-ketoglutarate-semialdehyde dehydrogenase (KGSADH) complexed with NAD 分子名称: Alpha-ketoglutaric semialdehyde dehydrogenase, GLYCEROL, NICOTINAMIDE-ADENINE-DINUCLEOTIDE 著者 Son, H.-F, Kim, K.-J. 登録日 2017-02-17 公開日 2017-05-10 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Structural insights into the production of 3-hydroxypropionic acid by aldehyde dehydrogenase from Azospirillum brasilense. Sci Rep, 7, 2017
4BAE	Optimisation of pyrroleamides as mycobacterial GyrB ATPase inhibitors: Structure Activity Relationship and in vivo efficacy in the mouse model of tuberculosis 分子名称: 2-[(3S,4R)-4-[(3-bromanyl-4-chloranyl-5-methyl-1H-pyrrol-2-yl)carbonylamino]-3-methoxy-piperidin-1-yl]-4-(2-methyl-1,2,4-triazol-3-yl)-1,3-thiazole-5-carboxylic acid, CALCIUM ION, DNA GYRASE SUBUNIT B, ... 著者 Read, J.A, Gingell, H.G, Madhavapeddi, P. 登録日 2012-09-13 公開日 2013-10-30 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.35 Å) 主引用文献 Optimization of Pyrrolamides as Mycobacterial Gyrb ATPase Inhibitors: Structure Activity Relationship and in Vivo Efficacy in the Mouse Model of Tuberculosis. Antimicrob.Agents Chemother., 58, 2014
5HN0	Dengue serotype 3 RNA-dependent RNA polymerase bound to compound 4 分子名称: (6-hydroxybiphenyl-3-yl)acetic acid, RNA-directed RNA polymerase NS5, ZINC ION 著者 Noble, C.G. 登録日 2016-01-17 公開日 2016-03-30 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 Discovery of Potent Non-Nucleoside Inhibitors of Dengue Viral RNA-Dependent RNA Polymerase from a Fragment Hit Using Structure-Based Drug Design. J.Med.Chem., 59, 2016
5VTB	Crystal structure of RBBP4 bound to BCL11a peptide 分子名称: B-cell lymphoma/leukemia 11A, GLYCEROL, Histone-binding protein RBBP4 著者 Meagher, J.L, Stuckey, J.A. 登録日 2017-05-16 公開日 2017-12-27 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Probing the interaction between the histone methyltransferase/deacetylase subunit RBBP4/7 and the transcription factor BCL11A in epigenetic complexes. J. Biol. Chem., 293, 2018
5HX8	Jak1 complex with 4-[(4-aminocyclohexyl)amino]-3-(1H-benzimidazol-2-yl)-1H-pyridin-2-one 分子名称: 4-[(4-aminocyclohexyl)amino]-3-(1H-benzimidazol-2-yl)-1H-pyridin-2-one, Tyrosine-protein kinase JAK1 著者 Su, H.P. 登録日 2016-01-29 公開日 2016-03-16 最終更新日 2017-11-22 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Structure-based design and development of (benz)imidazole pyridones as JAK1-selective kinase inhibitors. Bioorg.Med.Chem.Lett., 26, 2016
5HWT	Crystal structure of apo-PAS1 分子名称: Sensor histidine kinase TodS 著者 Hwang, J, Koh, S. 登録日 2016-01-29 公開日 2016-03-02 最終更新日 2017-12-06 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Molecular Insights into Toluene Sensing in the TodS/TodT Signal Transduction System. J. Biol. Chem., 291, 2016
5XUY	Crystal structure of ATG101-ATG13HORMA 分子名称: Autophagy-related protein 101, Autophagy-related protein 13 著者 Kim, B.-W, Song, H.K. 登録日 2017-06-26 公開日 2018-07-04 最終更新日 2024-03-27 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 The C-terminal region of ATG101 bridges ULK1 and PtdIns3K complex in autophagy initiation. Autophagy, 14, 2018
5W5K	Crystal structure of Danio rerio histone deacetylase 6 catalytic domain 2 in complex with KV70 分子名称: 10-{[4-(hydroxycarbamoyl)phenyl]methyl}-5lambda~4~-pyrido[3,2-b][1,4]benzothiazin-10-ium, Histone deacetylase 6, POTASSIUM ION, ... 著者 Porter, N.J, Christianson, D.W. 登録日 2017-06-15 公開日 2018-06-27 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Synthesis and Biological Investigation of Phenothiazine-Based Benzhydroxamic Acids as Selective Histone Deacetylase 6 Inhibitors. J.Med.Chem., 62, 2019
1S6I	Ca2+-regulatory region (CLD) from soybean calcium-dependent protein kinase-alpha (CDPK) in the presence of Ca2+ and the junction domain (JD) 分子名称: CALCIUM ION, Calcium-dependent protein kinase SK5 著者 Weljie, A.M, Vogel, H.J. 登録日 2004-01-23 公開日 2004-06-15 最終更新日 2024-05-22 実験手法 SOLUTION NMR 主引用文献 Unexpected structure of the Ca2+-regulatory region from soybean calcium-dependent protein kinase-alpha J.Biol.Chem., 279, 2004
6AHC	Cryo-EM structure of aldehyde-alcohol dehydrogenase reveals a high-order helical architecture critical for its activity 分子名称: Aldehyde-alcohol dehydrogenase 著者 Kim, G, Song, J.J. 登録日 2018-08-17 公開日 2019-08-21 最終更新日 2024-03-27 実験手法 ELECTRON MICROSCOPY (3.45 Å) 主引用文献 Aldehyde-alcohol dehydrogenase forms a high-order spirosome architecture critical for its activity. Nat Commun, 10, 2019
4BYY	Apo GlxR 分子名称: GLYCEROL, PHOSPHATE ION, TRANSCRIPTIONAL REGULATOR, ... 著者 Pohl, E, Cann, M.J, Townsend, P.D, Money, V.A. 登録日 2013-07-21 公開日 2014-07-30 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.48 Å) 主引用文献 The Crystal Structures of Apo and Camp-Bound Glxr from Corynebacterium Glutamicum Reveal Structural and Dynamic Changes Upon Camp Binding in Crp/Fnr Family Transcription Factors. Plos One, 9, 2014
1QKN	RAT OESTROGEN RECEPTOR BETA LIGAND-BINDING DOMAIN IN COMPLEX WITH ANTAGONIST RALOXIFENE 分子名称: ACETATE ION, ESTROGEN RECEPTOR BETA, RALOXIFENE 著者 Pike, A.C.W, Brzozowski, A.M, Carlquist, M. 登録日 1999-07-27 公開日 2000-07-28 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.25 Å) 主引用文献 Structure of the Ligand-Binding Domain of Oestrogen Receptor Beta in the Presence of a Partial Agonist and a Full Antagonist Embo J., 18, 1999
1QKM	HUMAN OESTROGEN RECEPTOR BETA LIGAND-BINDING DOMAIN IN COMPLEX WITH PARTIAL AGONIST GENISTEIN 分子名称: ESTROGEN RECEPTOR BETA, GENISTEIN 著者 Pike, A.C.W, Brzozowski, A.M, Carlquist, M. 登録日 1999-07-27 公開日 2000-07-28 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Structure of the Ligand-Binding Domain of Oestrogen Receptor Beta in the Presence of a Partial Agonist and a Full Antagonist Embo J., 18, 1999
3V3C	Crystal Structure of Chloroplast ATP synthase c-ring from Pisum sativum 分子名称: ATP synthase subunit c, chloroplastic, DIGALACTOSYL DIACYL GLYCEROL (DGDG), ... 著者 Saroussi, S, Nelson, N. 登録日 2011-12-13 公開日 2012-10-03 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (3.402 Å) 主引用文献 Structure and flexibility of the C-ring in the electromotor of rotary F(o)F(1)-ATPase of pea chloroplasts. Plos One, 7, 2012
2D4Y	Crystal structure of a 49K fragment of HAP1 (FlgK) 分子名称: Flagellar hook-associated protein 1 著者 Imada, K, Matsunami, H, Samatey, A.F, Nagashima, S, Namba, K. 登録日 2005-10-25 公開日 2006-11-14 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Structure of the bacterial flagellar hook-filament junction To be Published

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