3A33
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3a33 by Molmil](/molmil-images/mine/3a33) | UbcH5b~Ubiquitin Conjugate | 分子名称: | GLYCEROL, Ubiquitin, Ubiquitin-conjugating enzyme E2 D2 | 著者 | Sakata, E, Satoh, T, Yamamoto, S, Yamaguchi, Y, Yagi-Utsumi, M, Kurimoto, E, Wakatsuki, S, Kato, K. | 登録日 | 2009-06-08 | 公開日 | 2009-11-24 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Crystal Structure of UbcH5b~Ubiquitin Intermediate: Insight into the Formation of the Self-Assembled E2~Ub Conjugates Structure, 18, 2010
|
|
1JYJ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1jyj by Molmil](/molmil-images/mine/1jyj) | Crystal Structure of a Double Variant (W67L/W91H) of Recombinant Human Serum Retinol-binding Protein at 2.0 A Resolution | 分子名称: | GLYCEROL, PLASMA RETINOL-BINDING PROTEIN | 著者 | Greene, L.H, Chrysina, E.D, Irons, L.I, Papageorgiou, A.C, Acharya, K.R, Brew, K. | 登録日 | 2001-09-12 | 公開日 | 2003-07-01 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Role of Conserved Residues in Structure and Stability: Tryptophans of Human Serum Retinol-Binding Protein, a Model for the Lipocalin Superfamily Protein Sci., 10, 2001
|
|
3FFX
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3ffx by Molmil](/molmil-images/mine/3ffx) | Crystal Structure of CheY triple mutant F14E, N59R, E89H complexed with BeF3- and Mn2+ | 分子名称: | BERYLLIUM TRIFLUORIDE ION, Chemotaxis protein cheY, GLYCEROL, ... | 著者 | Pazy, Y, Collins, E.J, Bourret, R.B. | 登録日 | 2008-12-04 | 公開日 | 2009-09-22 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2.01 Å) | 主引用文献 | Matching Biochemical Reaction Kinetics to the Timescales of Life: Structural Determinants That Influence the Autodephosphorylation Rate of Response Regulator Proteins. J.Mol.Biol., 392, 2009
|
|
1K05
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1k05 by Molmil](/molmil-images/mine/1k05) | |
2J7T
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2j7t by Molmil](/molmil-images/mine/2j7t) | Crystal structure of human serine threonine kinase-10 bound to SU11274 | 分子名称: | (3Z)-N-(3-CHLOROPHENYL)-3-({3,5-DIMETHYL-4-[(4-METHYLPIPERAZIN-1-YL)CARBONYL]-1H-PYRROL-2-YL}METHYLENE)-N-METHYL-2-OXOINDOLINE-5-SULFONAMIDE, ACETATE ION, CALCIUM ION, ... | 著者 | Pike, A.C.W, Rellos, P, Fedorov, O, Das, S, Debreczeni, J, Sobott, F, Watt, S, Savitsky, P, Eswaran, J, Turnbull, A.P, Papagrigoriou, E, Ugochukwa, E, Gorrec, F, Umeano, C.C, von Delft, F, Arrowsmith, C.H, Edwards, A, Weigelt, J, Sundstrom, M, Knapp, S. | 登録日 | 2006-10-17 | 公開日 | 2006-11-07 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Activation Segment Dimerization: A Mechanism for Kinase Autophosphorylation of Non-Consensus Sites. Embo J., 27, 2008
|
|
1DZZ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1dzz by Molmil](/molmil-images/mine/1dzz) | |
3O6W
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3o6w by Molmil](/molmil-images/mine/3o6w) | Crystal structure of monomeric KlHxk1 in crystal form VIII (open state) | 分子名称: | GLYCEROL, Hexokinase, PHOSPHATE ION | 著者 | Kuettner, E.B, Kettner, K, Keim, A, Kriegel, T.M, Strater, N. | 登録日 | 2010-07-29 | 公開日 | 2010-10-13 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.48 Å) | 主引用文献 | Crystal Structure of Hexokinase KlHxk1 of Kluyveromyces lactis: A MOLECULAR BASIS FOR UNDERSTANDING THE CONTROL OF YEAST HEXOKINASE FUNCTIONS VIA COVALENT MODIFICATION AND OLIGOMERIZATION. J.Biol.Chem., 285, 2010
|
|
3EZJ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3ezj by Molmil](/molmil-images/mine/3ezj) | Crystal structure of the N-terminal domain of the secretin GspD from ETEC determined with the assistance of a nanobody | 分子名称: | CHLORIDE ION, General secretion pathway protein GspD, NANOBODY NBGSPD_7, ... | 著者 | Korotkov, K.V, Pardon, E, Steyaert, J, Hol, W.G. | 登録日 | 2008-10-22 | 公開日 | 2009-02-17 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Crystal structure of the N-terminal domain of the secretin GspD from ETEC determined with the assistance of a nanobody. Structure, 17, 2009
|
|
2Y4L
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2y4l by Molmil](/molmil-images/mine/2y4l) | MANNOSYLGLYCERATE SYNTHASE IN COMPLEX WITH Manganese and GDP | 分子名称: | 1,2-ETHANEDIOL, GUANOSINE-5'-DIPHOSPHATE, MALONATE ION, ... | 著者 | Nielsen, M.M, Suits, M.D.L, Yang, M, Barry, C.S, Martinez-Fleites, C, Tailford, L.E, Flint, J.E, Davis, B.G, Davies, G.J, Gilbert, H.J. | 登録日 | 2011-01-07 | 公開日 | 2011-02-02 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Substrate and Metal Ion Promiscuity in Mannosylglycerate Synthase. J.Biol.Chem., 286, 2011
|
|
2XDU
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2xdu by Molmil](/molmil-images/mine/2xdu) | Structure of HSP90 with small molecule inhibitor bound | 分子名称: | 1-CHLORO-4-METHYLPHTHALAZINE, DIMETHYL SULFOXIDE, HEAT SHOCK PROTEIN HSP 90-ALPHA, ... | 著者 | Murray, C.W, Carr, M.G, Callaghan, O, Chessari, G, Congreve, M, Cowan, S, Coyle, J.E, Downham, R, Figueroa, E, Frederickson, M, Graham, B, McMenamin, R, OBrien, M.A, Patel, S, Phillips, T.R, Williams, G, Woodhead, A.J, Woolford, A.J.A. | 登録日 | 2010-05-07 | 公開日 | 2010-09-01 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (1.74 Å) | 主引用文献 | Fragment-Based Drug Discovery Applied to Hsp90. Discovery of Two Lead Series with High Ligand Efficiency. J.Med.Chem., 53, 2010
|
|
6F26
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6f26 by Molmil](/molmil-images/mine/6f26) | Crystal structure of human Casein Kinase I delta in complex with compound 31b | 分子名称: | (9~{S},10~{S},11~{R})-~{N}-[4-[3-(4-fluorophenyl)-5-propan-2-yl-1,2-oxazol-4-yl]pyridin-2-yl]-4-(4-methoxyphenyl)-10,11-bis(oxidanyl)-1,7-diazatricyclo[7.3.0.0^{3,7}]dodeca-3,5-diene-6-carboxamide, Casein kinase I isoform delta, SULFATE ION | 著者 | Pichlo, C, Brunstein, E, Baumann, U. | 登録日 | 2017-11-23 | 公開日 | 2019-03-13 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.83 Å) | 主引用文献 | Design, Synthesis and Biological Evaluation of Isoxazole-Based CK1 Inhibitors Modified with Chiral Pyrrolidine Scaffolds. Molecules, 24, 2019
|
|
2Y3E
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2y3e by Molmil](/molmil-images/mine/2y3e) | Traptavidin, apo-form | 分子名称: | GLYCEROL, STREPTAVIDIN | 著者 | Chivers, C.E, Koner, A.L, Lowe, E.D, Howarth, M. | 登録日 | 2010-12-20 | 公開日 | 2011-02-16 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.449 Å) | 主引用文献 | How the Biotin-Streptavidin Interaction Was Made Even Stronger: Investigation Via Crystallography and a Chimeric Tetramer. Biochem.J., 435, 2011
|
|
6F34
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6f34 by Molmil](/molmil-images/mine/6f34) | |
6EX0
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6ex0 by Molmil](/molmil-images/mine/6ex0) | |
6F3H
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6f3h by Molmil](/molmil-images/mine/6f3h) | Crystal structure of Dss1 exoribonuclease active site mutant D477N from Candida glabrata | 分子名称: | Exoribonuclease II, mitochondrial, MAGNESIUM ION, ... | 著者 | Razew, M, Nowak, E, Nowotny, M. | 登録日 | 2017-11-28 | 公開日 | 2018-01-17 | 実験手法 | X-RAY DIFFRACTION (2.703 Å) | 主引用文献 | Structural analysis of mtEXO mitochondrial RNA degradosome reveals tight coupling of nuclease and helicase components. Nat Commun, 9, 2018
|
|
4QH8
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4qh8 by Molmil](/molmil-images/mine/4qh8) | LC8 - Ana2 (237-246) Complex | 分子名称: | Anastral spindle 2, Dynein light chain 1, cytoplasmic | 著者 | Slevin, L.K, Romes, E.R, Dandulakis, M.G, Slep, K.C. | 登録日 | 2014-05-27 | 公開日 | 2014-06-11 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | The Mechanism of Dynein Light Chain LC8-mediated Oligomerization of the Ana2 Centriole Duplication Factor. J.Biol.Chem., 289, 2014
|
|
3IMT
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3imt by Molmil](/molmil-images/mine/3imt) | |
5BO4
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5bo4 by Molmil](/molmil-images/mine/5bo4) | Structure of SOCS2:Elongin C:Elongin B from DMSO-treated crystals | 分子名称: | Suppressor of cytokine signaling 2, Transcription elongation factor B polypeptide 1, Transcription elongation factor B polypeptide 2 | 著者 | Gadd, M.S, Bulatov, E, Ciulli, A. | 登録日 | 2015-05-27 | 公開日 | 2015-07-08 | 最終更新日 | 2017-10-18 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Serendipitous SAD Solution for DMSO-Soaked SOCS2-ElonginC-ElonginB Crystals Using Covalently Incorporated Dimethylarsenic: Insights into Substrate Receptor Conformational Flexibility in Cullin RING Ligases. Plos One, 10, 2015
|
|
3IB9
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3ib9 by Molmil](/molmil-images/mine/3ib9) | Propionyl-CoA Carboxylase Beta Subunit, D422L | 分子名称: | BIOTIN, Propionyl-CoA carboxylase complex B subunit, SULFATE ION | 著者 | Diacovich, L, Arabolaza, A, Shillito, E.M, Lin, T.-W, Mitchell, D.L, Pham, H, Melgar, M.M. | 登録日 | 2009-07-15 | 公開日 | 2010-06-02 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Crystal structures and mutational analyses of acyl-CoA carboxylase beta subunit of Streptomyces coelicolor. Biochemistry, 49, 2010
|
|
3F2I
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3f2i by Molmil](/molmil-images/mine/3f2i) | Crystal structure of the alr0221 protein from Nostoc, Northeast Structural Genomics Consortium Target NsR422. | 分子名称: | Alr0221 protein, CHLORIDE ION, PHOSPHATE ION | 著者 | Forouhar, F, Lew, S, Seetharaman, J, Sahdev, S, Xiao, R, Foote, E.L, Ciccosanti, C, Belote, R.L, Nair, R, Everett, J.K, Acton, T.B, Rost, B, Montelione, G.T, Tong, L, Hunt, J.F, Northeast Structural Genomics Consortium (NESG) | 登録日 | 2008-10-29 | 公開日 | 2008-11-18 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Crystal structure of the alr0221 protein from Nostoc, Northeast Structural Genomics Consortium Target NsR422. To be Published
|
|
4LG5
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4lg5 by Molmil](/molmil-images/mine/4lg5) | ABA-mimicking ligand QUINABACTIN in complex with ABA receptor PYL2 and PP2C HAB1 | 分子名称: | Abscisic acid receptor PYL2, MAGNESIUM ION, Protein phosphatase 2C 16, ... | 著者 | Zhou, X.E, Gao, M, Liu, X, Zhang, Y, Xue, X, Melcher, K, Gao, P, Wang, F, Zeng, L, Zhao, Y, Zhao, Y, Deng, P, Zhong, D, Zhu, J.-K, Xu, Y, Xu, H.E. | 登録日 | 2013-06-27 | 公開日 | 2013-08-14 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.88 Å) | 主引用文献 | An ABA-mimicking ligand that reduces water loss and promotes drought resistance in plants. Cell Res., 23, 2013
|
|
5BNE
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5bne by Molmil](/molmil-images/mine/5bne) | |
4LGA
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4lga by Molmil](/molmil-images/mine/4lga) | ABA-mimicking ligand N-(2-OXO-1-PROPYL-1,2,3,4-TETRAHYDROQUINOLIN-6-YL)-1-PHENYLMETHANESULFONAMIDE in complex with ABA receptor PYL2 and PP2C HAB1 | 分子名称: | Abscisic acid receptor PYL2, MAGNESIUM ION, N-(2-oxo-1-propyl-1,2,3,4-tetrahydroquinolin-6-yl)-1-phenylmethanesulfonamide, ... | 著者 | Zhou, X.E, Gao, M, Liu, X, Zhang, Y, Xue, X, Melcher, K, Gao, P, Wang, F, Zeng, L, Zhao, Y, Zhao, Y, Deng, P, Zhong, D, Zhu, J.-K, Xu, Y, Xu, H.E. | 登録日 | 2013-06-27 | 公開日 | 2013-08-14 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | An ABA-mimicking ligand that reduces water loss and promotes drought resistance in plants. Cell Res., 23, 2013
|
|
6F59
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6f59 by Molmil](/molmil-images/mine/6f59) | Crystal structure of human Brachyury (T) G177D variant in complex with DNA | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, Brachyury protein, DNA (26-MER), ... | 著者 | Newman, J.A, Gavard, A.E, Krojer, T, Shrestha, L, Burgess-Brown, N.A, von Delft, F, Arrowsmith, C.H, Edwards, A, Bountra, C, Gileadi, O. | 登録日 | 2017-12-01 | 公開日 | 2017-12-13 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.151 Å) | 主引用文献 | Crystal structure of human Brachyury (T) G177D variant in complex with DNA To Be Published
|
|
6H38
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6h38 by Molmil](/molmil-images/mine/6h38) | The crystal structure of human carbonic anhydrase VII in complex with 4-[(4-fluorophenyl)methyl]-1-piperazinyl]benzenesulfonamide. | 分子名称: | 4-[4-[(4-fluorophenyl)methyl]piperazin-1-yl]carbonylbenzenesulfonamide, Carbonic anhydrase 7, GLYCEROL, ... | 著者 | Buemi, M.R, Di Fiore, A, De Luca, L, Ferro, S, Mancuso, F, Monti, S.M, Buonanno, M, Angeli, A, Russo, E, De Sarro, G, Supuran, C.T, De Simone, G, Gitto, R. | 登録日 | 2018-07-17 | 公開日 | 2018-12-19 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Exploring structural properties of potent human carbonic anhydrase inhibitors bearing a 4-(cycloalkylamino-1-carbonyl)benzenesulfonamide moiety. Eur J Med Chem, 163, 2018
|
|