6EX0

Crystal structure of RelP (SAS2) from Staphylococcus aureus bound to pppGpp in the post-catalytic state

Summary for 6EX0

Entry DOI	10.2210/pdb6ex0/pdb
Descriptor	GTP pyrophosphokinase, guanosine 5'-(tetrahydrogen triphosphate) 3'-(trihydrogen diphosphate), FE (II) ION, ... (4 entities in total)
Functional Keywords	stringent response, (p)ppgpp, persistence, small alarmone synthetase, transferase
Biological source	Staphylococcus aureus
Total number of polymer chains	2
Total formula weight	57610.40
Authors	Manav, M.C.,Brodersen, D.E. (deposition date: 2017-11-07, release date: 2018-01-24, Last modification date: 2024-01-17)
Primary citation	Manav, M.C.,Beljantseva, J.,Bojer, M.S.,Tenson, T.,Ingmer, H.,Hauryliuk, V.,Brodersen, D.E. Structural basis for (p)ppGpp synthesis by theStaphylococcus aureussmall alarmone synthetase RelP. J. Biol. Chem., 293:3254-3264, 2018 Cited by PubMed: 29326162 DOI: 10.1074/jbc.RA117.001374 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.78 Å)

Structure validation