6F59
Crystal structure of human Brachyury (T) G177D variant in complex with DNA
Summary for 6F59
Entry DOI | 10.2210/pdb6f59/pdb |
Descriptor | DNA (26-MER), Brachyury protein, SODIUM ION, ... (5 entities in total) |
Functional Keywords | chordoma, brachyury, t-box, transcription |
Biological source | Homo sapiens (Human) More |
Cellular location | Nucleus : O15178 |
Total number of polymer chains | 4 |
Total formula weight | 60274.31 |
Authors | Newman, J.A.,Gavard, A.E.,Krojer, T.,Shrestha, L.,Burgess-Brown, N.A.,von Delft, F.,Arrowsmith, C.H.,Edwards, A.,Bountra, C.,Gileadi, O. (deposition date: 2017-12-01, release date: 2017-12-13, Last modification date: 2024-01-17) |
Primary citation | Newman, J.A.,Gavard, A.E.,Krojer, T.,Shrestha, L.,Burgess-Brown, N.A.,von Delft, F.,Arrowsmith, C.H.,Edwards, A.,Bountra, C.,Gileadi, O. Crystal structure of human Brachyury (T) G177D variant in complex with DNA To Be Published, |
Experimental method | X-RAY DIFFRACTION (2.151 Å) |
Structure validation
Download full validation report