PDB: 2317 件ウェブページステータス検索Chemie searchBIRD

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1KV3	HUMAN TISSUE TRANSGLUTAMINASE IN GDP BOUND FORM 分子名称: GUANOSINE-5'-DIPHOSPHATE, Protein-glutamine gamma-glutamyltransferase 著者 Liu, S, Cerione, R.A, Clardy, J. 登録日 2002-01-24 公開日 2002-03-13 最終更新日 2023-08-16 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Structural basis for the guanine nucleotide-binding activity of tissue transglutaminase and its regulation of transamidation activity. Proc.Natl.Acad.Sci.USA, 99, 2002
4YT6	Factor VIIa in complex with the inhibitor 4-{[(R)-[5-ethoxy-2-fluoro-3-(propan-2-yloxy)phenyl](4-phenyl-1H-imidazol-2-yl)methyl]amino}benzenecarboximidamide 分子名称: 4-[[(R)-(5-ethoxy-2-fluoranyl-3-propan-2-yloxy-phenyl)-(4-phenyl-1H-imidazol-2-yl)methyl]amino]benzenecarboximidamide, CALCIUM ION, Coagulation factor VII (heavy chain), ... 著者 Wei, A. 登録日 2015-03-17 公開日 2015-04-29 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.07 Å) 主引用文献 Design and synthesis of potent, selective phenylimidazole-based FVIIa inhibitors. Bioorg.Med.Chem.Lett., 25, 2015
4YT7	Factor VIIa in complex with the inhibitor 2-(2-{(R)-[(4-carbamimidoylphenyl)amino][5-ethoxy-2-fluoro-3-(propan-2-yloxy)phenyl]methyl}-1H-imidazol-4-yl)benzamide 分子名称: 2-[2-[(R)-[(4-carbamimidoylphenyl)amino]-(5-ethoxy-2-fluoranyl-3-propan-2-yloxy-phenyl)methyl]-1H-imidazol-4-yl]benzamide, CALCIUM ION, Coagulation factor VII (heavy chain), ... 著者 Wei, A. 登録日 2015-03-17 公開日 2015-04-29 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Design and synthesis of potent, selective phenylimidazole-based FVIIa inhibitors. Bioorg.Med.Chem.Lett., 25, 2015
3OJM	Crystal Structure of FGF1 complexed with the ectodomain of FGFR2b harboring P253R Apert mutation 分子名称: Fibroblast growth factor receptor 2, Heparin-binding growth factor 1, SULFATE ION 著者 Beenken, A, Mohammadi, M. 登録日 2010-08-23 公開日 2011-08-31 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Plasticity in Interactions of Fibroblast Growth Factor 1 (FGF1) N Terminus with FGF Receptors Underlies Promiscuity of FGF1. J.Biol.Chem., 287, 2012
3OJ2	Crystal structure of FGF1 complexed with the ectodomain of FGFR2b harboring the A172F Pfeiffer syndrome mutation 分子名称: Fibroblast growth factor receptor 2, Heparin-binding growth factor 1, SULFATE ION 著者 Beenken, A, Mohammadi, M. 登録日 2010-08-20 公開日 2011-08-31 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Plasticity in Interactions of Fibroblast Growth Factor 1 (FGF1) N Terminus with FGF Receptors Underlies Promiscuity of FGF1. J.Biol.Chem., 287, 2012
3OJV	Crystal Structure of FGF1 complexed with the ectodomain of FGFR1c exhibiting an ordered ligand specificity-determining betaC'-betaE loop 分子名称: 4-deoxy-2-O-sulfo-alpha-L-threo-hex-4-enopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose, Basic fibroblast growth factor receptor 1, Heparin-binding growth factor 1 著者 Beenken, A, Mohammadi, M. 登録日 2010-08-23 公開日 2011-12-28 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Plasticity in Interactions of Fibroblast Growth Factor 1 (FGF1) N Terminus with FGF Receptors Underlies Promiscuity of FGF1. J.Biol.Chem., 287, 2012
4NG9	Factor viia in complex with the inhibitor (2R)-2-[(1-aminoisoquinolin-6-yl)amino]-2-[3-ethoxy-4-(propan-2-yloxy)phenyl]-n-(3-sulfamoylbenzyl)ethanamide 分子名称: (2R)-2-[(1-aminoisoquinolin-6-yl)amino]-2-[3-ethoxy-4-(propan-2-yloxy)phenyl]-N-(3-sulfamoylbenzyl)ethanamide, CALCIUM ION, Factor VIIa (Heavy Chain), ... 著者 Wei, A, Anumula, R. 登録日 2013-11-01 公開日 2014-01-08 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Design and Synthesis of Phenylpyrrolidine Phenylglycinamides As Highly Potent and Selective TF-FVIIa Inhibitors. ACS Med Chem Lett, 5, 2014
5ZXE	Structure of a consensus sequence derived from the FGF family 分子名称: CHLORIDE ION, Consensus sequence based basic form of fibroblast growth factor, GLYCEROL, ... 著者 Tripathi, S.K, Mandalaparthy, V, Ramaswamy, S, Gosavi, S. 登録日 2018-05-19 公開日 2019-07-24 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.3 Å) 主引用文献 Structure of a consensus sequence derived from the FGF family To be published
7S7M	Complex of tissue inhibitor of metalloproteinases-1 (TIMP-1) mutant (L34G/M66D/T98G/P131S/Q153N) with matrix metalloproteinase-3 catalytic domain (MMP-3cd) 分子名称: CALCIUM ION, Metalloproteinase inhibitor 1, Stromelysin-1, ... 著者 Coban, M, Raeeszadeh-Sarmazdeh, M, Sankaran, B, Hockla, A, Radisky, E.S. 登録日 2021-09-16 公開日 2022-03-16 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Engineering of tissue inhibitor of metalloproteinases TIMP-1 for fine discrimination between closely related stromelysins MMP-3 and MMP-10. J.Biol.Chem., 298, 2022
7S7L	Complex of tissue inhibitor of metalloproteinases-1 (TIMP-1) mutant (L34G/M66S/E67Y/L133N/S155L) with matrix metalloproteinase-3 catalytic domain (MMP-3cd) 分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ACETATE ION, CALCIUM ION, ... 著者 Coban, M, Raeeszadeh-Sarmazdeh, M, Hockla, A, Sankaran, B, Radisky, E.S. 登録日 2021-09-16 公開日 2022-03-16 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.34 Å) 主引用文献 Engineering of tissue inhibitor of metalloproteinases TIMP-1 for fine discrimination between closely related stromelysins MMP-3 and MMP-10. J.Biol.Chem., 298, 2022
5VQP	Crystal structure of human pro-TGF-beta1 分子名称: Transforming growth factor beta-1, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose 著者 Zhao, B, Xu, S, Dong, X, Lu, C, Springer, T.A. 登録日 2017-05-09 公開日 2017-11-15 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Prodomain-growth factor swapping in the structure of pro-TGF-beta 1. J. Biol. Chem., 293, 2018
2G7R	X-ray structure of the death domain of the human mucosa associated lymphoid tissue lymphoma translocation protein 1 分子名称: Mucosa-associated lymphoid tissue lymphoma translocation protein 1 著者 Walker, J.R, Wybenga-Groot, L, Newman, E.M, Finerty Jr, P.J, Butler-Cole, C, Weigelt, J, Sundstrom, M, Arrowsmith, C, Edwards, A, Bochkarev, A, Dhe-Paganon, S, Structural Genomics Consortium (SGC) 登録日 2006-02-28 公開日 2006-04-04 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 X-ray structure of the death domain of the human mucosa associated lymphoid tissue lymphoma translocation protein 1 To be Published
7U8D	FKBP12 mutant V55G bound to Rapa*-3Z 分子名称: (3S,5Z,6R,7E,9R,10R,12R,14S,15E,17E,19E,21S,23S,26R,27R,30R,34aS)-5-(ethoxyimino)-9,27-dihydroxy-3-{(2R)-1-[(1S,3R,4R)-4-hydroxy-3-methoxycyclohexyl]propan-2-yl}-10,21-dimethoxy-6,8,12,14,20,26-hexamethyl-5,6,9,10,12,13,14,21,22,23,24,25,26,27,32,33,34,34a-octadecahydro-3H-23,27-epoxypyrido[2,1-c][1,4]oxazacyclohentriacontine-1,11,28,29(4H,31H)-tetrone, GLYCEROL, Peptidyl-prolyl cis-trans isomerase FKBP1A 著者 Wassarman, D.R, Shokat, K.M. 登録日 2022-03-08 公開日 2022-09-21 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.39 Å) 主引用文献 Tissue-restricted inhibition of mTOR using chemical genetics. Proc.Natl.Acad.Sci.USA, 119, 2022
7AAO	Structural evolution of the tissue-specific U2AF2 paralog and alternative splicing factor LS2 分子名称: U2 snRNP auxiliary factor large subunit 著者 Kawale, A.A, Kang, H.S, Sattler, M. 登録日 2020-09-04 公開日 2021-10-06 最終更新日 2023-06-14 実験手法 SOLUTION NMR 主引用文献 Structural evolution of the tissue-specific U2AF2 paralog and alternative splicing factor LS2 To Be Published
7AAF	Structural evolution of the tissue-specific U2AF2 paralog and alternative splicing factor LS2 分子名称: U2 snRNP auxiliary factor large subunit 著者 Kawale, A.A, Kang, H.S, Sattler, M. 登録日 2020-09-04 公開日 2021-10-06 最終更新日 2023-06-14 実験手法 SOLUTION NMR 主引用文献 Structural evolution of the tissue-specific U2AF2 paralog and alternative splicing factor LS2 To Be Published
1WYR	Solution structure of the CH domain of human Rho guanine nucleotide exchange factor 6 分子名称: Rho guanine nucleotide exchange factor 6 著者 Tomizawa, T, Kigawa, T, Koshiba, S, Inoue, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) 登録日 2005-02-15 公開日 2005-08-15 最終更新日 2024-05-29 実験手法 SOLUTION NMR 主引用文献 Solution structure of the CH domain of human Rho guanine nucleotide exchange factor 6 To be Published
1TPG	F1-G MODULE PAIR RESIDUES 1-91 (C83S) OF TISSUE-TYPE PLASMINOGEN ACTIVATOR (T-PA) (NMR, 298K, PH2.95, REPRESENTATIVE STRUCTURE) 分子名称: T-PLASMINOGEN ACTIVATOR F1-G 著者 Smith, B.O, Downing, A.K, Driscoll, P.C, Dudgeon, T.J, Campbell, I.D. 登録日 1995-06-14 公開日 1995-09-15 最終更新日 2022-03-02 実験手法 SOLUTION NMR 主引用文献 The solution structure and backbone dynamics of the fibronectin type I and epidermal growth factor-like pair of modules of tissue-type plasminogen activator. Structure, 3, 1995
1WI8	Solution structure of the RNA binding domain of eukaryotic initiation factor 4B 分子名称: Eukaryotic translation initiation factor 4B 著者 Suzuki, S, Muto, Y, Nagata, T, Inoue, M, Kigawa, T, Terada, T, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) 登録日 2004-05-28 公開日 2004-11-28 最終更新日 2024-05-29 実験手法 SOLUTION NMR 主引用文献 Solution structure of the RNA binding domain of eukaryotic initiation factor 4B To be Published
3LGD	Crystal structure of human adenosine deaminase growth factor, adenosine deaminase type 2 (ADA2) 分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, Adenosine deaminase CECR1, ... 著者 Zavialov, A.V. 登録日 2010-01-20 公開日 2010-02-09 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structural basis for the growth factor activity of human adenosine deaminase ADA2. J.Biol.Chem., 285, 2010
2G97	Crystal Structure of Visfatin/Pre-B Cell Colony Enhancing Factor 1/Nicotinamide Phosphoribosyltransferase In Complex with the Specific Inhibitor FK-866 分子名称: (2E)-N-{4-[1-(benzenecarbonyl)piperidin-4-yl]butyl}-3-(pyridin-3-yl)prop-2-enamide, Nicotinamide phosphoribosyltransferase 著者 Kim, M.-K, Eom, S.H. 登録日 2006-03-05 公開日 2006-08-01 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Crystal Structure of Visfatin/Pre-B Cell Colony-enhancing Factor 1/Nicotinamide Phosphoribosyltransferase, Free and in Complex with the Anti-cancer Agent FK-866 J.Mol.Biol., 362, 2006
1F9P	CRYSTAL STRUCTURE OF CONNECTIVE TISSUE ACTIVATING PEPTIDE-III(CTAP-III) COMPLEXED WITH POLYVINYLSULFONIC ACID 分子名称: CONNECTIVE TISSUE ACTIVATING PEPTIDE-III, ETHANESULFONIC ACID 著者 Yang, J, Faulk, T, Aster, R, Visentin, G, Edwards, B, Castor, C. 登録日 2000-07-11 公開日 2003-08-26 最終更新日 2017-10-04 実験手法 X-RAY DIFFRACTION (1.93 Å) 主引用文献 Structure of the CXC Chemokine, Connective Tissue Activating Peptide-III, Complexed with the Heparin Analogue, Polyvinylsulfonic Acid To be Published
4RU2	Crystal structure of a RNA-binding protein 39 (RBM39) in complex with fragment of splicing factor (U2AF) from Mus musculus at 2.20 A resolution 分子名称: RNA-binding protein 39 (RBM39), Splicing factor U2AF 65 kDa subunit 著者 Joint Center for Structural Genomics (JCSG), Partnership for T-Cell Biology (TCELL) 登録日 2014-11-17 公開日 2015-02-04 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Crystal structure of a RNA-binding protein 39 (RBM39) in complex with fragment of splicing factor (U2AF) from Mus musculus at 2.20 A resolution To be published
5NTU	Crystal Structure of human Pro-myostatin Precursor at 2.6 A Resolution 分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, Growth/differentiation factor 8 著者 Cotton, T.R, Fischer, G, Hyvonen, M. 登録日 2017-04-28 公開日 2018-01-17 最終更新日 2018-02-21 実験手法 X-RAY DIFFRACTION (2.58 Å) 主引用文献 Structure of the human myostatin precursor and determinants of growth factor latency. EMBO J., 37, 2018
5NXS	Crystal Structure of Human Pro-myostatin Precursor at 4.2 A Resolution with Experimental Phases from SeMet labelling 分子名称: Growth/differentiation factor 8 著者 Cotton, T.R, Fischer, G, Hyvonen, M. 登録日 2017-05-10 公開日 2018-01-17 最終更新日 2018-02-21 実験手法 X-RAY DIFFRACTION (4.19 Å) 主引用文献 Structure of the human myostatin precursor and determinants of growth factor latency. EMBO J., 37, 2018
5VQF	Crystal Structure of pro-TGF-beta 1 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Transforming growth factor beta-1, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose 著者 Zhao, B, Xu, S, Dong, X, Lu, C, Springer, T.A. 登録日 2017-05-08 公開日 2017-11-15 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Prodomain-growth factor swapping in the structure of pro-TGF-beta 1. J. Biol. Chem., 293, 2018

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