PDB: 105044 件ウェブページステータス検索Chemie searchBIRD

---

4MB8	Evolutionary history and metabolic insights of ancient mammalian uricases 分子名称: ACETATE ION, Uricase 著者 Ortlund, E.O, Murphy, M.N. 登録日 2013-08-19 公開日 2014-02-05 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.4009 Å) 主引用文献 Evolutionary history and metabolic insights of ancient mammalian uricases. Proc.Natl.Acad.Sci.USA, 111, 2014
4MC8	Hedycaryol synthase in complex with HEPES 分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Putative sesquiterpene cyclase 著者 Baer, P, Rabe, P, Cirton, C, Oliveira Mann, C, Kaufmann, N, Groll, M, Dickschat, J. 登録日 2013-08-21 公開日 2014-01-29 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Hedycaryol synthase in complex with nerolidol reveals terpene cyclase mechanism. Chembiochem, 15, 2014
8CMV	Engineered PETase enzyme from LCC - C09 mutant 分子名称: GLYCEROL, ISOPROPYL ALCOHOL, Leaf-branch compost cutinase 著者 Bhattacharya, S, Estiri, H, Castagna, R, Parisini, E. 登録日 2023-02-21 公開日 2024-03-06 最終更新日 2024-11-13 実験手法 X-RAY DIFFRACTION (1.28 Å) 主引用文献 Development of a highly active engineered PETase enzyme for polyester degradation Biorxiv, 2024
1BZO	THREE-DIMENSIONAL STRUCTURE OF PROKARYOTIC CU,ZN SUPEROXIDE DISMUTASE FROM P.LEIOGNATHI, SOLVED BY X-RAY CRYSTALLOGRAPHY. 分子名称: COPPER (II) ION, PROTEIN (SUPEROXIDE DISMUTASE), URANYL (VI) ION, ... 著者 Bordo, D, Matak, D, Djinovic-Carugo, K, Rosano, C, Pesce, A, Bolognesi, M, Stroppolo, M.E, Falconi, M, Battistoni, A, Desideri, A. 登録日 1998-11-02 公開日 1999-04-09 最終更新日 2024-11-20 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Evolutionary constraints for dimer formation in prokaryotic Cu,Zn superoxide dismutase. J.Mol.Biol., 285, 1999
1TSH	TERTIARY STRUCTURES OF THREE AMYLOIDOGENIC TRANSTHYRETIN VARIANTS AND IMPLICATIONS FOR AMYLOID FIBRIL FORMATION 分子名称: TRANSTHYRETIN 著者 Schormann, N, Murrell, J.R, Benson, M.D. 登録日 1996-10-16 公開日 1997-04-21 最終更新日 2024-05-22 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Tertiary structures of amyloidogenic and non-amyloidogenic transthyretin variants: new model for amyloid fibril formation. Amyloid, 5, 1998
3IIV	Evolutionary optimization of computationally designed enzymes: Kemp eliminases of the KE07 series 分子名称: KE7 KE7_R7_1/3H, MAGNESIUM ION 著者 Khersonsky, O, Dym, O, Tawfik, D.S. 登録日 2009-08-03 公開日 2010-03-02 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Evolutionary Optimization of Computationally Designed Enzymes: Kemp Eliminases of the KE07 Series. J.Mol.Biol., 396, 2010
2FHK	Crystal structure of formylmethanofuran: tetrahydromethanopterin formyltransferase in complex with its coenzymes 分子名称: Formylmethanofuran--tetrahydromethanopterin formyltransferase, N-[4,5,7-TRICARBOXYHEPTANOYL]-L-GAMMA-GLUTAMYL-N-{2-[4-({5-[(FORMYLAMINO)METHYL]-3-FURYL}METHOXY)PHENYL]ETHYL}-D-GLUTAMINE, POTASSIUM ION 著者 Acharya, P, Warkentin, E, Thauer, R.K, Shima, S, Ermler, U. 登録日 2005-12-25 公開日 2006-03-07 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 The structure of formylmethanofuran: tetrahydromethanopterin formyltransferase in complex with its coenzymes J.Mol.Biol., 357, 2006
1ACJ	QUATERNARY LIGAND BINDING TO AROMATIC RESIDUES IN THE ACTIVE-SITE GORGE OF ACETYLCHOLINESTERASE 分子名称: ACETYLCHOLINESTERASE, TACRINE 著者 Sussman, J.L, Harel, M, Silman, I. 登録日 1993-08-18 公開日 1994-08-31 最終更新日 2024-11-13 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Quaternary ligand binding to aromatic residues in the active-site gorge of acetylcholinesterase. Proc.Natl.Acad.Sci.USA, 90, 1993
1ACL	QUATERNARY LIGAND BINDING TO AROMATIC RESIDUES IN THE ACTIVE-SITE GORGE OF ACETYLCHOLINESTERASE 分子名称: ACETYLCHOLINESTERASE, DECAMETHONIUM ION 著者 Sussman, J.L, Harel, M, Silman, I. 登録日 1993-08-18 公開日 1994-08-31 最終更新日 2024-11-13 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Quaternary ligand binding to aromatic residues in the active-site gorge of acetylcholinesterase. Proc.Natl.Acad.Sci.USA, 90, 1993
1W5R	X-ray crystallographic structure of a C70Q Mycobacterium smegmatis N- arylamine Acetyltransferase 分子名称: ARYLAMINE N-ACETYLTRANSFERASE 著者 Holton, S.J, Sandy, J, Rodrigues-Lima, F, Dupret, J.-M, Bhakta, S, Noble, M.E.M, Sim, E. 登録日 2004-08-09 公開日 2005-05-11 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.45 Å) 主引用文献 Investigation of the Catalytic Triad of Arylamine N-Acetyltransferases: Essential Residues Required for Acetyl Transfer to Arylamines. Biochem.J., 390, 2005
3IIO	Evolutionary optimization of computationally designed enzymes: Kemp eliminases of the KE07 series 分子名称: KE07 著者 Khersonsky, O, Dym, O, Tawfik, D.S. 登録日 2009-08-03 公開日 2010-03-02 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.25 Å) 主引用文献 Evolutionary Optimization of Computationally Designed Enzymes: Kemp Eliminases of the KE07 Series. J.Mol.Biol., 396, 2010
5WRE	Hepatitis B virus core protein Y132A mutant in complex with heteroaryldihydropyrimidine (HAP_R01) 分子名称: (2S)-1-[[(4R)-4-(2-chloranyl-4-fluoranyl-phenyl)-5-methoxycarbonyl-2-(1,3-thiazol-2-yl)-1,4-dihydropyrimidin-6-yl]methyl]-4,4-bis(fluoranyl)pyrrolidine-2-carboxylic acid, CHLORIDE ION, Core protein, ... 著者 Zhou, Z, Xu, Z.H. 登録日 2016-12-01 公開日 2017-02-22 最終更新日 2024-10-23 実験手法 X-RAY DIFFRACTION (1.946 Å) 主引用文献 Heteroaryldihydropyrimidine (HAP) and Sulfamoylbenzamide (SBA) Inhibit Hepatitis B Virus Replication by Different Molecular Mechanisms. Sci Rep, 7, 2017
2FHJ	Crystal structure of formylmethanofuran: tetrahydromethanopterin formyltransferase in complex with its coenzymes 分子名称: 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, 3,6,9,12,15,18,21,24,27,30,33,36,39-TRIDECAOXAHENTETRACONTANE-1,41-DIOL, 5-(4-{[1-(2-AMINO-5-FORMYL-7-METHYL-4-OXO-3,4,5,6,7,8-HEXAHYDROPTERIDIN-6-YL)ETHYL]AMINO}PHENYL)-5-DEOXY-1-O-{5-O-[(1,3-DICARBOXYPROPOXY)(HYDROXY)PHOSPHORYL]PENTOFURANOSYL}PENTITOL, ... 著者 Acharya, P, Warkentin, E, Thauer, R.K, Shima, S, Ermler, U. 登録日 2005-12-25 公開日 2006-03-07 最終更新日 2024-11-06 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 The structure of formylmethanofuran: tetrahydromethanopterin formyltransferase in complex with its coenzymes J.Mol.Biol., 357, 2006
3IIP	Evolutionary optimization of computationally designed enzymes: Kemp eliminases of the KE07 series 分子名称: KE7 R6 3/7F, POLYETHYLENE GLYCOL (N=34) 著者 Khersonsky, O, Dym, O, Tawfik, D.S. 登録日 2009-08-03 公開日 2010-03-02 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Evolutionary Optimization of Computationally Designed Enzymes: Kemp Eliminases of the KE07 Series. J.Mol.Biol., 396, 2010
1N95	Aryl Tetrahydrophyridine Inhbitors of Farnesyltranferase: Glycine, Phenylalanine and Histidine Derivatives 分子名称: 1-[2-(4-CYANO-BENZYLAMINO)-3-(3-METHYL-3H-IMIDAZOL-4-YL)-PROPIONYL]-5-NAPHTHALEN-1-YL-1,2,3,6-TETRAHYDRO-PYRIDINE-4-CARBONITRILE, ALPHA-HYDROXYFARNESYLPHOSPHONIC ACID, Protein farnesyltransferase alpha subunit, ... 著者 Gwaltney II, S.L, O'Conner, S.J, Nelson, L.T, Sullivan, G.M, Imade, H, Wang, W, Hasvold, L, Li, Q, Cohen, J, Gu, W.Z. 登録日 2002-11-22 公開日 2003-01-07 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Aryl tetrahydropyridine inhibitors of farnesyltransferase: glycine, phenylalanine and histidine derivatives. Bioorg.Med.Chem.Lett., 13, 2003
1N94	Aryl Tetrahydropyridine Inhbitors of Farnesyltransferase: Glycine, Phenylalanine and Histidine Derivates 分子名称: 2-{(5-{[BUTYL-(2-CYCLOHEXYL-ETHYL)-AMINO]-METHYL}-2'-METHYL-BIPHENYL-2-CARBONYL)-AMINO]-4-METHYLSULFANYL-BUTYRIC ACID, ALPHA-HYDROXYFARNESYLPHOSPHONIC ACID, Protein farnesyltransferase alpha subunit, ... 著者 Gwaltney II, S.L, O'Connor, S.J, Nelson, L.T, Sullivan, G.M, Imade, H, Wang, W, Hasvold, L, Li, Q, Cohen, J, Gu, W.Z. 登録日 2002-11-22 公開日 2003-01-07 最終更新日 2024-12-25 実験手法 X-RAY DIFFRACTION (3.5 Å) 主引用文献 Aryl tetrahydropyridine inhibitors of farnesyltransferase: glycine, phenylalanine and histidine derivatives. Bioorg.Med.Chem.Lett., 13, 2003
4MC0	Hedycaryol apo 分子名称: Putative sesquiterpene cyclase 著者 Baer, P, Rabe, P, Cirton, C, Oliveira Mann, C, Kaufmann, N, Groll, M, Dickschat, J. 登録日 2013-08-21 公開日 2014-01-29 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Hedycaryol synthase in complex with nerolidol reveals terpene cyclase mechanism. Chembiochem, 15, 2014
3HAD	BIOCHEMICAL CHARACTERIZATION AND STRUCTURE DETERMINATION OF HUMAN HEART SHORT CHAIN L-3-HYDROXYACYL COA DEHYDROGENASE PROVIDE INSIGHT INTO CATALYTIC MECHANISM 分子名称: NICOTINAMIDE-ADENINE-DINUCLEOTIDE, PROTEIN (L-3-HYDROXYACYL COA DEHYDROGENASE) 著者 Barycki, J.J, Bratt, J.M, Banaszak, L.J. 登録日 1998-12-03 公開日 2000-01-12 最終更新日 2024-05-22 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Biochemical characterization and crystal structure determination of human heart short chain L-3-hydroxyacyl-CoA dehydrogenase provide insights into catalytic mechanism. Biochemistry, 38, 1999
1STE	STAPHYLOCOCCAL ENTEROTOXIN C2 FROM STAPHYLOCOCCUS AUREUS 分子名称: STAPHYLOCOCCAL ENTEROTOXIN C2, ZINC ION 著者 Acharya, K.R, Papageorgiou, A.C. 登録日 1995-08-21 公開日 1996-12-23 最終更新日 2024-10-30 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Crystal structure of the superantigen enterotoxin C2 from Staphylococcus aureus reveals a zinc-binding site. Structure, 3, 1995
1A56	PRIMARY SEQUENCE AND SOLUTION CONFORMATION OF FERRICYTOCHROME C-552 FROM NITROSOMONAS EUROPAEA, NMR, MEAN STRUCTURE REFINED WITH EXPLICIT HYDROGEN BOND CONSTRAINTS 分子名称: FERRICYTOCHROME C-552, HEME C 著者 Timkovich, R, Bergmann, D, Arciero, D.M, Hooper, A.B. 登録日 1998-02-20 公開日 1998-10-21 最終更新日 2024-10-09 実験手法 SOLUTION NMR 主引用文献 Primary sequence and solution conformation of ferrocytochrome c-552 from Nitrosomonas europaea. Biophys.J., 75, 1998
1A8C	PRIMARY SEQUENCE AND SOLUTION CONFORMATION OF FERROCYTOCHROME C-552 FROM NITROSOMONAS EUROPAEA, NMR, MEAN STRUCTURE REFINED WITHOUT HYDROGEN BOND CONSTRAINTS 分子名称: FERROCYTOCHROME C-552, HEME C 著者 Timkovich, R, Bergmann, D, Arciero, D.M, Hooper, A.B. 登録日 1998-03-23 公開日 1998-10-21 最終更新日 2024-10-30 実験手法 SOLUTION NMR 主引用文献 Primary sequence and solution conformation of ferrocytochrome c-552 from Nitrosomonas europaea. Biophys.J., 75, 1998
4REK	Crystal structure and charge density studies of cholesterol oxidase from Brevibacterium sterolicum at 0.74 ultra-high resolution 分子名称: Cholesterol oxidase, FLAVIN-ADENINE DINUCLEOTIDE, PHOSPHATE ION 著者 Zarychta, B, Lyubimov, A, Ahmed, M, Munshi, P, Guillot, B, Vrielink, A. 登録日 2014-09-23 公開日 2015-04-15 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (0.74 Å) 主引用文献 Cholesterol oxidase: ultrahigh-resolution crystal structure and multipolar atom model-based analysis. Acta Crystallogr.,Sect.D, 71, 2015
4KM3	Discovery of a novel structural motif in methionine aminopeptidase from Streptococci with possible post-translational modification 分子名称: Methionine aminopeptidase 著者 Arya, T, Addlagatta, A. 登録日 2013-05-08 公開日 2014-01-15 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 Discovery of a new genetic variant of methionine aminopeptidase from streptococci with possible post-translational modifications: biochemical and structural characterization. Plos One, 8, 2013
1W6F	Arylamine N-acetyltransferase from Mycobacterium smegmatis with the anti-tubercular drug isoniazid bound in the active site. 分子名称: 4-(DIAZENYLCARBONYL)PYRIDINE, ARYLAMINE N-ACETYLTRANSFERASE 著者 Sandy, J, Holton, S, Fullham, E, Sim, E, Noble, M.E.M. 登録日 2004-08-17 公開日 2005-02-23 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Binding of the Anti-Tubercular Drug Isoniazid to the Arylamine N-Acetyltransferase Protein from Mycobacterium Smegmatis Protein Sci., 14, 2005
2QKS	Crystal structure of a Kir3.1-prokaryotic Kir channel chimera 分子名称: Kir3.1-prokaryotic Kir channel chimera, POTASSIUM ION, nonyl beta-D-glucopyranoside 著者 Nishida, M, MacKinnon, R. 登録日 2007-07-11 公開日 2007-08-28 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Crystal structure of a Kir3.1-prokaryotic Kir channel chimera. Embo J., 26, 2007

<234567891011121314151617>