1W6F
Arylamine N-acetyltransferase from Mycobacterium smegmatis with the anti-tubercular drug isoniazid bound in the active site.
Summary for 1W6F
| Entry DOI | 10.2210/pdb1w6f/pdb |
| Related | 1GX3 1W5R |
| Descriptor | ARYLAMINE N-ACETYLTRANSFERASE, 4-(DIAZENYLCARBONYL)PYRIDINE (3 entities in total) |
| Functional Keywords | nat, tuberculosis, acetyltransferase, transferase |
| Biological source | MYCOBACTERIUM SMEGMATIS |
| Cellular location | Cytoplasm: O86309 |
| Total number of polymer chains | 4 |
| Total formula weight | 122805.79 |
| Authors | Sandy, J.,Holton, S.,Fullham, E.,Sim, E.,Noble, M.E.M. (deposition date: 2004-08-17, release date: 2005-02-23, Last modification date: 2023-12-13) |
| Primary citation | Sandy, J.,Holton, S.,Fullham, E.,Sim, E.,Noble, M.E.M. Binding of the Anti-Tubercular Drug Isoniazid to the Arylamine N-Acetyltransferase Protein from Mycobacterium Smegmatis Protein Sci., 14:775-, 2005 Cited by PubMed: 15722451DOI: 10.1110/PS.041163505 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.1 Å) |
Structure validation
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