3HAD

BIOCHEMICAL CHARACTERIZATION AND STRUCTURE DETERMINATION OF HUMAN HEART SHORT CHAIN L-3-HYDROXYACYL COA DEHYDROGENASE PROVIDE INSIGHT INTO CATALYTIC MECHANISM

Summary for 3HAD

Entry DOI	10.2210/pdb3had/pdb
Descriptor	PROTEIN (L-3-HYDROXYACYL COA DEHYDROGENASE), NICOTINAMIDE-ADENINE-DINUCLEOTIDE (3 entities in total)
Functional Keywords	oxidoreductase, beta oxidation, schad, catalytic activity: l-3-hydroxyacyl-coa + nad(+) = 3-oxoacyl-coa + nadh
Biological source	Homo sapiens (human)
Cellular location	Mitochondrion matrix: Q16836
Total number of polymer chains	2
Total formula weight	68742.05
Authors	Barycki, J.J.,Bratt, J.M.,Banaszak, L.J. (deposition date: 1998-12-03, release date: 2000-01-12, Last modification date: 2022-12-21)
Primary citation	Barycki, J.J.,O'Brien, L.K.,Bratt, J.M.,Zhang, R.,Sanishvili, R.,Strauss, A.W.,Banaszak, L.J. Biochemical characterization and crystal structure determination of human heart short chain L-3-hydroxyacyl-CoA dehydrogenase provide insights into catalytic mechanism. Biochemistry, 38:5786-5798, 1999 Cited by PubMed: 10231530 DOI: 10.1021/bi9829027 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2 Å)

Structure validation