3HAD

BIOCHEMICAL CHARACTERIZATION AND STRUCTURE DETERMINATION OF HUMAN HEART SHORT CHAIN L-3-HYDROXYACYL COA DEHYDROGENASE PROVIDE INSIGHT INTO CATALYTIC MECHANISM

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	PROTEIN (L-3-HYDROXYACYL COA DEHYDROGENASE)	polymer	308	33707.6	2	UniProt (Q16836) Pfam (PF02737) Pfam (PF00725)	Homo sapiens (human)	SCHAD
2	C, D (A, B)	NICOTINAMIDE-ADENINE-DINUCLEOTIDE	non-polymer		663.4	2	Chemie (NAD)
3	E, F (A, B)	water	water		18.0	319	Chemie (HOH)

Sequence modifications

A, B: 1 - 302 (UniProt: Q16836)

PDB	External Database	Details
Arg 125	Phe 137	variant
Gln 140	His 152	variant
His 303	-	expression tag
His 304	-	expression tag
His 305	-	expression tag
His 306	-	expression tag
His 307	-	expression tag
His 308	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	67415.2
Non-Polymers*	Number of molecules	2
	Total formula weight	1326.8
All*	Total formula weight	68742.1

*Water molecules are not included.