2CI9
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![BU of 2ci9 by Molmil](/molmil-images/mine/2ci9) | Nck1 SH2-domain in complex with a dodecaphosphopeptide from EPEC protein Tir | 分子名称: | CYTOPLASMIC PROTEIN NCK1, TRANSLOCATED INTIMIN RECEPTOR | 著者 | Frese, S, Schubert, W.-D, Findeis, A.C, Marquardt, T, Roske, Y.S, Stradal, T.E.B, Heinz, D.W. | 登録日 | 2006-03-17 | 公開日 | 2006-04-24 | 最終更新日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | The Phosphotyrosine Peptide Binding Specificity of Nck1 and Nck2 Src Homology 2 Domains. J.Biol.Chem., 281, 2006
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2EKX
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![BU of 2ekx by Molmil](/molmil-images/mine/2ekx) | Solution structure of the human BMX SH2 domain | 分子名称: | Cytoplasmic tyrosine-protein kinase BMX | 著者 | Kasai, T, Koshiba, S, Watanabe, S, Harada, T, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | 登録日 | 2007-03-26 | 公開日 | 2007-10-02 | 最終更新日 | 2024-05-29 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution structure of the human BMX SH2 domain To be Published
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2CIA
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![BU of 2cia by Molmil](/molmil-images/mine/2cia) | human nck2 sh2-domain in complex with a decaphosphopeptide from translocated intimin receptor (tir) of epec | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, CYTOPLASMIC PROTEIN NCK2, ISOPROPYL ALCOHOL, ... | 著者 | Frese, S, Schubert, W.-D, Findeis, A.C, Marquardt, T, Roske, Y.S, Stradal, T.E.B, Heinz, D.W. | 登録日 | 2006-03-17 | 公開日 | 2006-04-24 | 最終更新日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | 主引用文献 | The Phosphotyrosine Peptide Binding Specificity of Nck1 and Nck2 Src Homology 2 Domains. J.Biol.Chem., 281, 2006
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2EO3
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![BU of 2eo3 by Molmil](/molmil-images/mine/2eo3) | |
2AOB
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![BU of 2aob by Molmil](/molmil-images/mine/2aob) | Crystal structures of a high-affinity macrocyclic peptide mimetic in complex with the Grb2 SH2 domain | 分子名称: | 2-(4-((9S,10S,14S,Z)-18-(2-AMINO-2-OXOETHYL)-9-(CARBOXYMETHYL)-14-(NAPHTHALEN-1-YLMETHYL)-8,17,20-TRIOXO-7,16,19-TRIAZASPIRO[5.14]ICOS-11-EN-10-YL)PHENYL)MALONIC ACID, Growth factor receptor-bound protein 2 | 著者 | Phan, J, Shi, Z.D, Burke, T.R, Waugh, D.S. | 登録日 | 2005-08-12 | 公開日 | 2005-10-04 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Crystal Structures of a High-affinity Macrocyclic Peptide Mimetic in Complex with the Grb2 SH2 Domain. J.Mol.Biol., 353, 2005
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2ECD
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![BU of 2ecd by Molmil](/molmil-images/mine/2ecd) | Solution structure of the human ABL2 SH2 domain | 分子名称: | Tyrosine-protein kinase ABL2 | 著者 | Kasai, T, Koshiba, S, Inoue, M, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | 登録日 | 2007-02-13 | 公開日 | 2008-02-19 | 最終更新日 | 2024-05-29 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution structure of the human ABL2 SH2 domain To be Published
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2EOB
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![BU of 2eob by Molmil](/molmil-images/mine/2eob) | Solution structure of the second SH2 domain from rat PLC gamma-2 | 分子名称: | 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma 2 | 著者 | Sano, R, Hayashi, F, Nagashima, T, Yoshida, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | 登録日 | 2007-03-29 | 公開日 | 2008-04-01 | 最終更新日 | 2024-05-29 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution structure of the second SH2 domain from rat PLC gamma-2 To be Published
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2EO6
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![BU of 2eo6 by Molmil](/molmil-images/mine/2eo6) | Solution structure of the SH2 domain from mouse B-cell linker protein BLNK | 分子名称: | B-cell linker protein | 著者 | Sano, R, Hayashi, F, Kurosaki, C, Yoshida, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | 登録日 | 2007-03-29 | 公開日 | 2008-04-01 | 最終更新日 | 2024-05-29 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution structure of the SH2 domain from mouse B-cell linker protein BLNK To be Published
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2BBU
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![BU of 2bbu by Molmil](/molmil-images/mine/2bbu) | |
2CS0
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![BU of 2cs0 by Molmil](/molmil-images/mine/2cs0) | |
2CRH
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![BU of 2crh by Molmil](/molmil-images/mine/2crh) | |
2EYV
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![BU of 2eyv by Molmil](/molmil-images/mine/2eyv) | |
2ETZ
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![BU of 2etz by Molmil](/molmil-images/mine/2etz) | The NMR minimized average structure of the Itk SH2 domain bound to a phosphopeptide | 分子名称: | Lymphocyte cytosolic protein 2 phosphopeptide fragment, Tyrosine-protein kinase ITK/TSK | 著者 | Sundd, M, Pletneva, E.V, Fulton, D.B, Andreotti, A.H. | 登録日 | 2005-10-27 | 公開日 | 2006-02-07 | 最終更新日 | 2022-03-09 | 実験手法 | SOLUTION NMR | 主引用文献 | Molecular Details of Itk Activation by Prolyl Isomerization and Phospholigand Binding: The NMR Structure of the Itk SH2 Domain Bound to a Phosphopeptide. J.Mol.Biol., 357, 2006
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2DCR
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![BU of 2dcr by Molmil](/molmil-images/mine/2dcr) | |
2EU0
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![BU of 2eu0 by Molmil](/molmil-images/mine/2eu0) | The NMR ensemble structure of the Itk SH2 domain bound to a phosphopeptide | 分子名称: | Lymphocyte cytosolic protein 2 phosphopeptide fragment, Tyrosine-protein kinase ITK/TSK | 著者 | Sundd, M, Pletneva, E.V, Fulton, D.B, Andreotti, A.H. | 登録日 | 2005-10-27 | 公開日 | 2006-02-07 | 最終更新日 | 2022-03-09 | 実験手法 | SOLUTION NMR | 主引用文献 | Molecular Details of Itk Activation by Prolyl Isomerization and Phospholigand Binding: The NMR Structure of the Itk SH2 Domain Bound to a Phosphopeptide. J.Mol.Biol., 357, 2006
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2DX0
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![BU of 2dx0 by Molmil](/molmil-images/mine/2dx0) | Crystal structure of the N-terminal SH2 domain of mouse phospholipase C-gamma 2 | 分子名称: | Phospholipase C, gamma 2, SULFATE ION | 著者 | Handa, N, Takagi, T, Murayama, K, Terada, T, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | 登録日 | 2006-08-22 | 公開日 | 2007-09-04 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Crystal structure of the N-terminal SH2 domain of mouse phospholipase C-gamma 2 To be Published
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2DM0
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![BU of 2dm0 by Molmil](/molmil-images/mine/2dm0) | |
2DLZ
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![BU of 2dlz by Molmil](/molmil-images/mine/2dlz) | |
2FCI
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![BU of 2fci by Molmil](/molmil-images/mine/2fci) | Structural basis for the requirement of two phosphotyrosines in signaling mediated by Syk tyrosine kinase | 分子名称: | C-termainl SH2 domain from phospholipase C-gamma-1 comprising residues 663-759, Doubly phosphorylated peptide derived from Syk kinase comprising residues 338-350 | 著者 | Groesch, T.D, Zhou, F, Mattila, S, Geahlen, R.L, Post, C.B. | 登録日 | 2005-12-12 | 公開日 | 2006-01-31 | 最終更新日 | 2023-11-15 | 実験手法 | SOLUTION NMR | 主引用文献 | Structural basis for the requirement of two phosphotyrosine residues in signaling mediated by syk tyrosine kinase J.Mol.Biol., 356, 2006
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2CR4
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![BU of 2cr4 by Molmil](/molmil-images/mine/2cr4) | Solution structure of the SH2 domain of human SH3BP2 protein | 分子名称: | SH3 domain-binding protein 2 | 著者 | Hatta, R, Tomizawa, T, Hayashi, F, Yoshida, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | 登録日 | 2005-05-20 | 公開日 | 2005-11-20 | 最終更新日 | 2024-05-29 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution structure of the SH2 domain of human SH3BP2 protein To be Published
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1A1A
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![BU of 1a1a by Molmil](/molmil-images/mine/1a1a) | |
1AB2
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![BU of 1ab2 by Molmil](/molmil-images/mine/1ab2) | THREE-DIMENSIONAL SOLUTION STRUCTURE OF THE SRC HOMOLOGY 2 DOMAIN OF C-ABL | 分子名称: | C-ABL TYROSINE KINASE SH2 DOMAIN | 著者 | Overduin, M, Rios, C.B, Mayer, B.J, Baltimore, D, Cowburn, D. | 登録日 | 1993-07-19 | 公開日 | 1994-01-31 | 最終更新日 | 2024-05-22 | 実験手法 | SOLUTION NMR | 主引用文献 | Three-dimensional solution structure of the src homology 2 domain of c-abl. Cell(Cambridge,Mass.), 70, 1992
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1AOU
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![BU of 1aou by Molmil](/molmil-images/mine/1aou) | NMR STRUCTURE OF THE FYN SH2 DOMAIN COMPLEXED WITH A PHOSPHOTYROSYL PEPTIDE, 22 STRUCTURES | 分子名称: | FYN PROTEIN-TYROSINE KINASE, PHOSPHOTYROSYL PEPTIDE | 著者 | Mulhern, T.D, Shaw, G.L, Morton, C.J, Day, A.J, Campbell, I.D. | 登録日 | 1997-07-10 | 公開日 | 1998-01-14 | 最終更新日 | 2021-11-03 | 実験手法 | SOLUTION NMR | 主引用文献 | The SH2 domain from the tyrosine kinase Fyn in complex with a phosphotyrosyl peptide reveals insights into domain stability and binding specificity. Structure, 5, 1997
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1BFI
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![BU of 1bfi by Molmil](/molmil-images/mine/1bfi) | SOLUTION STRUCTURE OF THE C-TERMINAL SH2 DOMAIN OF THE P85ALPHA REGULATORY SUBUNIT OF PHOSPHOINOSITIDE 3-KINASE, NMR, 30 STRUCTURES | 分子名称: | P85 ALPHA | 著者 | Siegal, G, Davis, B, Kristensen, S.M, Sankar, A, Linacre, J, Stein, R.C, Panayotou, G, Waterfield, M.D, Driscoll, P.C. | 登録日 | 1997-11-18 | 公開日 | 1998-02-25 | 最終更新日 | 2024-05-22 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution structure of the C-terminal SH2 domain of the p85 alpha regulatory subunit of phosphoinositide 3-kinase. J.Mol.Biol., 276, 1998
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1AYA
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![BU of 1aya by Molmil](/molmil-images/mine/1aya) | |