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2CI9
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Nck1 SH2-domain in complex with a dodecaphosphopeptide from EPEC protein Tir
分子名称: CYTOPLASMIC PROTEIN NCK1, TRANSLOCATED INTIMIN RECEPTOR
著者Frese, S, Schubert, W.-D, Findeis, A.C, Marquardt, T, Roske, Y.S, Stradal, T.E.B, Heinz, D.W.
登録日2006-03-17
公開日2006-04-24
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献The Phosphotyrosine Peptide Binding Specificity of Nck1 and Nck2 Src Homology 2 Domains.
J.Biol.Chem., 281, 2006
2EKX
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Solution structure of the human BMX SH2 domain
分子名称: Cytoplasmic tyrosine-protein kinase BMX
著者Kasai, T, Koshiba, S, Watanabe, S, Harada, T, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2007-03-26
公開日2007-10-02
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Solution structure of the human BMX SH2 domain
To be Published
2CIA
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human nck2 sh2-domain in complex with a decaphosphopeptide from translocated intimin receptor (tir) of epec
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, CYTOPLASMIC PROTEIN NCK2, ISOPROPYL ALCOHOL, ...
著者Frese, S, Schubert, W.-D, Findeis, A.C, Marquardt, T, Roske, Y.S, Stradal, T.E.B, Heinz, D.W.
登録日2006-03-17
公開日2006-04-24
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (1.45 Å)
主引用文献The Phosphotyrosine Peptide Binding Specificity of Nck1 and Nck2 Src Homology 2 Domains.
J.Biol.Chem., 281, 2006
2EO3
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Solution structure of the SH2 domain from human Crk-like protein
分子名称: Crk-like protein
著者Kurosaki, C, Yoshida, M, Hayashi, F, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2007-03-28
公開日2008-04-08
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Solution structure of the SH2 domain from human Crk-like protein
To be Published
2AOB
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Crystal structures of a high-affinity macrocyclic peptide mimetic in complex with the Grb2 SH2 domain
分子名称: 2-(4-((9S,10S,14S,Z)-18-(2-AMINO-2-OXOETHYL)-9-(CARBOXYMETHYL)-14-(NAPHTHALEN-1-YLMETHYL)-8,17,20-TRIOXO-7,16,19-TRIAZASPIRO[5.14]ICOS-11-EN-10-YL)PHENYL)MALONIC ACID, Growth factor receptor-bound protein 2
著者Phan, J, Shi, Z.D, Burke, T.R, Waugh, D.S.
登録日2005-08-12
公開日2005-10-04
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Crystal Structures of a High-affinity Macrocyclic Peptide Mimetic in Complex with the Grb2 SH2 Domain.
J.Mol.Biol., 353, 2005
2ECD
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Solution structure of the human ABL2 SH2 domain
分子名称: Tyrosine-protein kinase ABL2
著者Kasai, T, Koshiba, S, Inoue, M, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2007-02-13
公開日2008-02-19
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Solution structure of the human ABL2 SH2 domain
To be Published
2EOB
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Solution structure of the second SH2 domain from rat PLC gamma-2
分子名称: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma 2
著者Sano, R, Hayashi, F, Nagashima, T, Yoshida, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2007-03-29
公開日2008-04-01
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Solution structure of the second SH2 domain from rat PLC gamma-2
To be Published
2EO6
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Solution structure of the SH2 domain from mouse B-cell linker protein BLNK
分子名称: B-cell linker protein
著者Sano, R, Hayashi, F, Kurosaki, C, Yoshida, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2007-03-29
公開日2008-04-01
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Solution structure of the SH2 domain from mouse B-cell linker protein BLNK
To be Published
2BBU
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solution structure of mouse socs3 in complex with a phosphopeptide from the gp130 receptor
分子名称: GP130 PHOSPHOPEPTIDE, Suppressor of cytokine signaling 3
著者Babon, J.J, Yao, S, Norton, R.S.
登録日2005-10-17
公開日2006-05-02
最終更新日2022-03-09
実験手法SOLUTION NMR
主引用文献The Structure of SOCS3 Reveals the Basis of the Extended SH2 Domain Function and Identifies an Unstructured Insertion That Regulates Stability
Mol.Cell, 22, 2006
2CS0
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BU of 2cs0 by Molmil
Solution structure of the SH2 domain of human HSH2D protein
分子名称: Hematopoietic SH2 domain containing
著者Kurosaki, C, Hayashi, F, Yoshida, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2005-05-20
公開日2005-11-20
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Solution structure of the SH2 domain of human HSH2D protein
To be published
2CRH
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Solution structure of the SH2 domain of human proto-oncogene protein VAV1
分子名称: Vav proto-oncogene
著者Endo, H, Hayashi, F, Yoshida, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2005-05-20
公開日2005-11-20
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Solution structure of the SH2 domain of human proto-oncogene protein VAV1
to be published
2EYV
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SH2 domain of CT10-Regulated Kinase
分子名称: v-crk sarcoma virus CT10 oncogene homolog isoform a
著者Kobashigawa, Y, Tanaka, S, Inagaki, F.
登録日2005-11-10
公開日2006-11-10
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Structural basis for the transforming activity of human cancer-related signaling adaptor protein CRK.
Nat.Struct.Mol.Biol., 14, 2007
2ETZ
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The NMR minimized average structure of the Itk SH2 domain bound to a phosphopeptide
分子名称: Lymphocyte cytosolic protein 2 phosphopeptide fragment, Tyrosine-protein kinase ITK/TSK
著者Sundd, M, Pletneva, E.V, Fulton, D.B, Andreotti, A.H.
登録日2005-10-27
公開日2006-02-07
最終更新日2022-03-09
実験手法SOLUTION NMR
主引用文献Molecular Details of Itk Activation by Prolyl Isomerization and Phospholigand Binding: The NMR Structure of the Itk SH2 Domain Bound to a Phosphopeptide.
J.Mol.Biol., 357, 2006
2DCR
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Fully automated solution structure determination of the Fes SH2 domain
分子名称: Proto-oncogene tyrosine-protein kinase Fes/Fps
著者Lopez-Mendez, B, Guntert, P.
登録日2006-01-12
公開日2006-10-17
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Automated protein structure determination from NMR spectra
J.AM.CHEM.SOC., 128, 2006
2EU0
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The NMR ensemble structure of the Itk SH2 domain bound to a phosphopeptide
分子名称: Lymphocyte cytosolic protein 2 phosphopeptide fragment, Tyrosine-protein kinase ITK/TSK
著者Sundd, M, Pletneva, E.V, Fulton, D.B, Andreotti, A.H.
登録日2005-10-27
公開日2006-02-07
最終更新日2022-03-09
実験手法SOLUTION NMR
主引用文献Molecular Details of Itk Activation by Prolyl Isomerization and Phospholigand Binding: The NMR Structure of the Itk SH2 Domain Bound to a Phosphopeptide.
J.Mol.Biol., 357, 2006
2DX0
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BU of 2dx0 by Molmil
Crystal structure of the N-terminal SH2 domain of mouse phospholipase C-gamma 2
分子名称: Phospholipase C, gamma 2, SULFATE ION
著者Handa, N, Takagi, T, Murayama, K, Terada, T, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2006-08-22
公開日2007-09-04
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Crystal structure of the N-terminal SH2 domain of mouse phospholipase C-gamma 2
To be Published
2DM0
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Solution structure of the SH2 domain of human Tyrosine-protein kinase TXK
分子名称: Tyrosine-protein kinase TXK
著者Endo, H, Hayashi, F, Yoshida, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2006-04-20
公開日2006-10-20
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Solution structure of the SH2 domain of human Tyrosine-protein kinase TXK
To be Published
2DLZ
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Solution structure of the SH2 domain of human protein vav-2
分子名称: Protein vav-2
著者Endo, H, Hayashi, F, Yoshida, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2006-04-20
公開日2007-04-03
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Solution structure of the SH2 domain of human protein vav-2
To be Published
2FCI
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Structural basis for the requirement of two phosphotyrosines in signaling mediated by Syk tyrosine kinase
分子名称: C-termainl SH2 domain from phospholipase C-gamma-1 comprising residues 663-759, Doubly phosphorylated peptide derived from Syk kinase comprising residues 338-350
著者Groesch, T.D, Zhou, F, Mattila, S, Geahlen, R.L, Post, C.B.
登録日2005-12-12
公開日2006-01-31
最終更新日2023-11-15
実験手法SOLUTION NMR
主引用文献Structural basis for the requirement of two phosphotyrosine residues in signaling mediated by syk tyrosine kinase
J.Mol.Biol., 356, 2006
2CR4
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Solution structure of the SH2 domain of human SH3BP2 protein
分子名称: SH3 domain-binding protein 2
著者Hatta, R, Tomizawa, T, Hayashi, F, Yoshida, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2005-05-20
公開日2005-11-20
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Solution structure of the SH2 domain of human SH3BP2 protein
To be Published
1A1A
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C-SRC (SH2 DOMAIN WITH C188A MUTATION) COMPLEXED WITH ACE-FORMYL PHOSPHOTYR-GLU-(N,N-DIPENTYL AMINE)
分子名称: ACE-FORMYL PHOSPHOTYR-GLU-(N,N-DIPENTYL AMINE), C-SRC TYROSINE KINASE
著者Shewchuk, L, Jordan, S.
登録日1997-12-10
公開日1998-04-08
最終更新日2023-08-02
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Peptide ligands of pp60(c-src) SH2 domains: a thermodynamic and structural study.
Biochemistry, 36, 1997
1AB2
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THREE-DIMENSIONAL SOLUTION STRUCTURE OF THE SRC HOMOLOGY 2 DOMAIN OF C-ABL
分子名称: C-ABL TYROSINE KINASE SH2 DOMAIN
著者Overduin, M, Rios, C.B, Mayer, B.J, Baltimore, D, Cowburn, D.
登録日1993-07-19
公開日1994-01-31
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Three-dimensional solution structure of the src homology 2 domain of c-abl.
Cell(Cambridge,Mass.), 70, 1992
1AOU
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NMR STRUCTURE OF THE FYN SH2 DOMAIN COMPLEXED WITH A PHOSPHOTYROSYL PEPTIDE, 22 STRUCTURES
分子名称: FYN PROTEIN-TYROSINE KINASE, PHOSPHOTYROSYL PEPTIDE
著者Mulhern, T.D, Shaw, G.L, Morton, C.J, Day, A.J, Campbell, I.D.
登録日1997-07-10
公開日1998-01-14
最終更新日2021-11-03
実験手法SOLUTION NMR
主引用文献The SH2 domain from the tyrosine kinase Fyn in complex with a phosphotyrosyl peptide reveals insights into domain stability and binding specificity.
Structure, 5, 1997
1BFI
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SOLUTION STRUCTURE OF THE C-TERMINAL SH2 DOMAIN OF THE P85ALPHA REGULATORY SUBUNIT OF PHOSPHOINOSITIDE 3-KINASE, NMR, 30 STRUCTURES
分子名称: P85 ALPHA
著者Siegal, G, Davis, B, Kristensen, S.M, Sankar, A, Linacre, J, Stein, R.C, Panayotou, G, Waterfield, M.D, Driscoll, P.C.
登録日1997-11-18
公開日1998-02-25
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Solution structure of the C-terminal SH2 domain of the p85 alpha regulatory subunit of phosphoinositide 3-kinase.
J.Mol.Biol., 276, 1998
1AYA
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CRYSTAL STRUCTURES OF PEPTIDE COMPLEXES OF THE AMINO-TERMINAL SH2 DOMAIN OF THE SYP TYROSINE PHOSPHATASE
分子名称: PEPTIDE PDGFR-1009, PROTEIN-TYROSINE PHOSPHATASE SYP (N-TERMINAL SH2 DOMAIN)
著者Lee, C.-H, Kuriyan, J.
登録日1994-05-15
公開日1994-08-31
最終更新日2024-06-05
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Crystal structures of peptide complexes of the amino-terminal SH2 domain of the Syp tyrosine phosphatase.
Structure, 2, 1994

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