5TYI
 
 | | Grb7 SH2 with bicyclic peptide containing pY mimetic | | 分子名称: | Growth factor receptor-bound protein 7, Peptide inhibitor | | 著者 | Watson, G.M, Wilce, M.C.J, Wilce, J.A. | | 登録日 | 2016-11-20 | | 公開日 | 2017-11-15 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | | 主引用文献 | Discovery, Development, and Cellular Delivery of Potent and Selective Bicyclic Peptide Inhibitors of Grb7 Cancer Target.
J. Med. Chem., 60, 2017
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2BBU
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2CS0
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2EKX
 | | Solution structure of the human BMX SH2 domain | | 分子名称: | Cytoplasmic tyrosine-protein kinase BMX | | 著者 | Kasai, T, Koshiba, S, Watanabe, S, Harada, T, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | 登録日 | 2007-03-26 | | 公開日 | 2007-10-02 | | 最終更新日 | 2024-05-29 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structure of the human BMX SH2 domain
To be Published
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2CR4
 | | Solution structure of the SH2 domain of human SH3BP2 protein | | 分子名称: | SH3 domain-binding protein 2 | | 著者 | Hatta, R, Tomizawa, T, Hayashi, F, Yoshida, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | 登録日 | 2005-05-20 | | 公開日 | 2005-11-20 | | 最終更新日 | 2024-05-29 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structure of the SH2 domain of human SH3BP2 protein
To be Published
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2AOB
 | | Crystal structures of a high-affinity macrocyclic peptide mimetic in complex with the Grb2 SH2 domain | | 分子名称: | 2-(4-((9S,10S,14S,Z)-18-(2-AMINO-2-OXOETHYL)-9-(CARBOXYMETHYL)-14-(NAPHTHALEN-1-YLMETHYL)-8,17,20-TRIOXO-7,16,19-TRIAZASPIRO[5.14]ICOS-11-EN-10-YL)PHENYL)MALONIC ACID, Growth factor receptor-bound protein 2 | | 著者 | Phan, J, Shi, Z.D, Burke, T.R, Waugh, D.S. | | 登録日 | 2005-08-12 | | 公開日 | 2005-10-04 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Crystal Structures of a High-affinity Macrocyclic Peptide Mimetic in Complex with the Grb2 SH2 Domain.
J.Mol.Biol., 353, 2005
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5VKL
 | | SPT6 tSH2-RPB1 1476-1500 pS1493 | | 分子名称: | DNA-directed RNA polymerase II subunit RPB1, Transcription elongation factor SPT6 | | 著者 | Sdano, M.A, Whitby, F.G, Hill, C.P. | | 登録日 | 2017-04-21 | | 公開日 | 2017-10-25 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (2.198 Å) | | 主引用文献 | A novel SH2 recognition mechanism recruits Spt6 to the doubly phosphorylated RNA polymerase II linker at sites of transcription.
Elife, 6, 2017
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5TNW
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2EO3
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2AUG
 | | Crystal structure of the Grb14 SH2 domain | | 分子名称: | Growth factor receptor-bound protein 14 | | 著者 | Depetris, R.S, Hu, J, Gimpelevich, I, Holt, L.J, Daly, R.J, Hubbard, S.R. | | 登録日 | 2005-08-27 | | 公開日 | 2005-11-01 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Structural basis for inhibition of the insulin receptor by the adaptor protein grb14.
Mol.Cell, 20, 2005
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2ECD
 | | Solution structure of the human ABL2 SH2 domain | | 分子名称: | Tyrosine-protein kinase ABL2 | | 著者 | Kasai, T, Koshiba, S, Inoue, M, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | 登録日 | 2007-02-13 | | 公開日 | 2008-02-19 | | 最終更新日 | 2024-05-29 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structure of the human ABL2 SH2 domain
To be Published
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5W3R
 | | SH2B1 SH2 Domain | | 分子名称: | PHENOL, PHOSPHATE ION, SH2B adapter protein 1 | | 著者 | McKercher, M.A, Wuttke, D.S. | | 登録日 | 2017-06-08 | | 公開日 | 2017-11-22 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (1.386 Å) | | 主引用文献 | Diversity in peptide recognition by the SH2 domain of SH2B1.
Proteins, 86, 2018
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2EOB
 | | Solution structure of the second SH2 domain from rat PLC gamma-2 | | 分子名称: | 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma 2 | | 著者 | Sano, R, Hayashi, F, Nagashima, T, Yoshida, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | 登録日 | 2007-03-29 | | 公開日 | 2008-04-01 | | 最終更新日 | 2024-05-29 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structure of the second SH2 domain from rat PLC gamma-2
To be Published
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2EO6
 | | Solution structure of the SH2 domain from mouse B-cell linker protein BLNK | | 分子名称: | B-cell linker protein | | 著者 | Sano, R, Hayashi, F, Kurosaki, C, Yoshida, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | 登録日 | 2007-03-29 | | 公開日 | 2008-04-01 | | 最終更新日 | 2024-05-29 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structure of the SH2 domain from mouse B-cell linker protein BLNK
To be Published
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2CRH
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2DLY
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2DCR
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2EYV
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2ETZ
 | | The NMR minimized average structure of the Itk SH2 domain bound to a phosphopeptide | | 分子名称: | Lymphocyte cytosolic protein 2 phosphopeptide fragment, Tyrosine-protein kinase ITK/TSK | | 著者 | Sundd, M, Pletneva, E.V, Fulton, D.B, Andreotti, A.H. | | 登録日 | 2005-10-27 | | 公開日 | 2006-02-07 | | 最終更新日 | 2022-03-09 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Molecular Details of Itk Activation by Prolyl Isomerization and Phospholigand Binding: The NMR Structure of the Itk SH2 Domain Bound to a Phosphopeptide.
J.Mol.Biol., 357, 2006
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2EU0
 | | The NMR ensemble structure of the Itk SH2 domain bound to a phosphopeptide | | 分子名称: | Lymphocyte cytosolic protein 2 phosphopeptide fragment, Tyrosine-protein kinase ITK/TSK | | 著者 | Sundd, M, Pletneva, E.V, Fulton, D.B, Andreotti, A.H. | | 登録日 | 2005-10-27 | | 公開日 | 2006-02-07 | | 最終更新日 | 2022-03-09 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Molecular Details of Itk Activation by Prolyl Isomerization and Phospholigand Binding: The NMR Structure of the Itk SH2 Domain Bound to a Phosphopeptide.
J.Mol.Biol., 357, 2006
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1A1A
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1A09
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1A1E
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1AB2
 | | THREE-DIMENSIONAL SOLUTION STRUCTURE OF THE SRC HOMOLOGY 2 DOMAIN OF C-ABL | | 分子名称: | C-ABL TYROSINE KINASE SH2 DOMAIN | | 著者 | Overduin, M, Rios, C.B, Mayer, B.J, Baltimore, D, Cowburn, D. | | 登録日 | 1993-07-19 | | 公開日 | 1994-01-31 | | 最終更新日 | 2024-05-22 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Three-dimensional solution structure of the src homology 2 domain of c-abl.
Cell(Cambridge,Mass.), 70, 1992
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1AYD
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