1A09

C-src (SH2 domain) complexed with ace-formyl phosphotyr-glu-(n,n-dipentyl amine)

Summary for 1A09

DescriptorC-SRC TYROSINE KINASE, ACE-FORMYL PHOSPHOTYR-GLU-(N,N-DIPENTYL AMINE) (3 entities in total)
Functional Keywordscomplex (transferase-peptide), complex (transferase-peptide) complex, complex (transferase/peptide)
Biological sourceHomo sapiens (human)
Cellular locationCell membrane  P12931
Total number of polymer chains4
Total molecular weight25779.02
Authors
Shewchuk, L.,Jordan, S. (deposition date: 1997-12-10, release date: 1998-04-08, Last modification date: 2018-03-07)
Primary citation
Charifson, P.S.,Shewchuk, L.M.,Rocque, W.,Hummel, C.W.,Jordan, S.R.,Mohr, C.,Pacofsky, G.J.,Peel, M.R.,Rodriguez, M.,Sternbach, D.D.,Consler, T.G.
Peptide ligands of pp60(c-src) SH2 domains: a thermodynamic and structural study.
Biochemistry, 36:6283-6293, 1997
PubMed: 9174343 (PDB entries with the same primary citation)
DOI: 10.1021/bi970019n
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2 Å)
NMR Information
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Structure validation

ClashscoreRamachandran outliersSidechain outliersRSRZ outliers40.5%2.8%4.8%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution