PDB: 45797 件ウェブページステータス検索Chemie searchBIRD

---

1UTZ	Crystal Structure of MMP-12 complexed to (2R)-3-({[4-[(pyridin-4-yl)phenyl]-thien-2-yl}carboxamido)(phenyl)propanoic acid 分子名称: (2R)-3-({[4-[(PYRIDIN-4-YL)PHENYL]-THIEN-2-YL}CARBOXAMIDO)(PHENYL)PROPANOIC ACID, ACETOHYDROXAMIC ACID, CALCIUM ION, ... 著者 Morales, R, Perrier, S, Florent, J.M, Beltra, J, Dufour, S, De Mendez, I, Manceau, P, Tertre, A, Moreau, F, Compere, D, Dublanchet, A.C, O'Gara, M. 登録日 2003-12-12 公開日 2004-12-15 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Crystal Structures of Novel Non-Peptidic, Non-Zinc Chelating Inhibitors Bound to Mmp-12 J.Mol.Biol., 341, 2004
1USV	The Structure of the complex between Aha1 and HSP90 分子名称: AHA1, HEAT SHOCK PROTEIN HSP82 著者 Meyer, P, Roe, S.M, Pearl, L.H. 登録日 2003-12-01 公開日 2004-01-29 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Structural Basis for Recruitment of the ATPase Activator Aha1 to the Hsp90 Chaperone Machinery. Embo J., 23, 2004
1UVN	The structural basis for RNA specificity and Ca2 inhibition of an RNA-dependent RNA polymerase phi6p2 ca2+ inhibition complex 分子名称: 5'-R(*UP*UP*UP*UP*CP*CP)-3', CALCIUM ION, GUANOSINE-5'-TRIPHOSPHATE, ... 著者 Salgado, P.S, Makeyev, E.V, Butcher, S, Bamford, D, Stuart, D.I, Grimes, J.M. 登録日 2004-01-21 公開日 2004-02-26 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 The structural basis for RNA specificity and Ca2+ inhibition of an RNA-dependent RNA polymerase. Structure, 12, 2004
2AX7	Crystal Structure Of The Androgen Receptor Ligand Binding Domain T877A Mutant In Complex With S-1 分子名称: Androgen receptor, S-3-(4-FLUOROPHENOXY)-2-HYDROXY-2-METHYL-N-[4-NITRO-3-(TRIFLUOROMETHYL)PHENYL]PROPANAMIDE 著者 Bohl, C.E, Miller, D.D, Chen, J, Bell, C.E, Dalton, J.T. 登録日 2005-09-03 公開日 2005-09-20 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Structural Basis for Accommodation of Nonsteroidal Ligands in the Androgen Receptor J.Biol.Chem., 280, 2005
1UTT	Crystal Structure of MMP-12 complexed to 2-(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)ethyl-4-(4-ethoxy[1,1-biphenyl]-4-yl)-4-oxobutanoic acid 分子名称: 2-(1,3-DIOXO-1,3-DIHYDRO-2H-ISOINDOL-2-YL) ETHYL-4-(4'-ETHOXY [1,1'-BIPHENYL]-4-YL)-4-OXOBUTANOIC ACID, ACETOHYDROXAMIC ACID, CALCIUM ION, ... 著者 Morales, R, Perrier, S, Florent, J.M, Beltra, J, Dufour, S, De Mendez, I, Manceau, P, Tertre, A, Moreau, F, Compere, D, Dublanchet, A.C, O'Gara, M. 登録日 2003-12-10 公開日 2004-12-15 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Crystal structures of novel non-peptidic, non-zinc chelating inhibitors bound to MMP-12. J. Mol. Biol., 341, 2004
2AY2	AROMATIC AMINO ACID AMINOTRANSFERASE WITH CYCLOHEXANE PROPIONIC ACID 分子名称: AROMATIC AMINO ACID AMINOTRANSFERASE, CYCLOHEXANE PROPIONIC ACID, PYRIDOXAL-5'-PHOSPHATE 著者 Okamoto, A, Hirotsu, K, Kagamiyama, H. 登録日 1998-08-06 公開日 1999-02-02 最終更新日 2023-08-09 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 The active site of Paracoccus denitrificans aromatic amino acid aminotransferase has contrary properties: flexibility and rigidity. Biochemistry, 38, 1999
1CDL	TARGET ENZYME RECOGNITION BY CALMODULIN: 2.4 ANGSTROMS STRUCTURE OF A CALMODULIN-PEPTIDE COMPLEX 分子名称: CALCIUM ION, CALCIUM/CALMODULIN-DEPENDENT PROTEIN KINASE TYPE II ALPHA CHAIN, CALMODULIN 著者 Meador, W.E, Quiocho, F.A. 登録日 1993-10-08 公開日 1994-08-31 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Target enzyme recognition by calmodulin: 2.4 A structure of a calmodulin-peptide complex. Science, 257, 1992
2AYQ	3-ISOPROPYLMALATE DEHYDROGENASE FROM THE MODERATE FACULTATIVE THERMOPHILE, BACILLUS COAGULANS 分子名称: 3-ISOPROPYLMALATE DEHYDROGENASE 著者 Tsuchiya, D, Takenaka, A. 登録日 1998-02-20 公開日 1998-05-27 最終更新日 2024-05-22 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Crystal structure of 3-isopropylmalate dehydrogenase from the moderate facultative thermophile, Bacillus coagulans: two strategies for thermostabilization of protein structures. J.Biochem.(Tokyo), 122, 1997
1SVS	Structure of the K180P mutant of Gi alpha subunit bound to GppNHp. 分子名称: Guanine nucleotide-binding protein G(i), alpha-1 subunit, MAGNESIUM ION, ... 著者 Thomas, C.J, Du, X, Li, P, Wang, Y, Ross, E.M, Sprang, S.R. 登録日 2004-03-29 公開日 2004-06-01 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Uncoupling conformational change from GTP hydrolysis in a heterotrimeric G protein {alpha}-subunit. Proc.Natl.Acad.Sci.USA, 101, 2004
2AZ9	HIV-1 Protease NL4-3 1X mutant 分子名称: PROTEASE RETROPEPSIN, benzyl [(1S,4S,7S,8R,9R,10S,13S,16S)-7,10-dibenzyl-8,9-dihydroxy-1,16-dimethyl-4,13-bis(1-methylethyl)-2,5,12,15,18-pentaoxo-20-phenyl-19-oxa-3,6,11,14,17-pentaazaicos-1-yl]carbamate 著者 Heaslet, H, Kutilek, V, Morris, G.M, Lin, Y.-C, Elder, J.H, Torbett, B.E, Stout, C.D. 登録日 2005-09-09 公開日 2006-02-28 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Structural Insights into the Mechanisms of Drug Resistance in HIV-1 Protease NL4-3 J.Mol.Biol., 356, 2006
1TC6	Ligand Induced Conformational Shift in the N-terminal Domain of GRP94, Open Conformation ADP-Complex 分子名称: ADENOSINE-5'-DIPHOSPHATE, Endoplasmin, MAGNESIUM ION, ... 著者 Gewirth, D.T, Immormino, R.M, Dollins, D.E, Shaffer, P.L, Walker, M.A, Soldano, K.L. 登録日 2004-05-20 公開日 2004-08-24 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (1.87 Å) 主引用文献 Ligand-induced Conformational Shift in the N-terminal Domain of GRP94, an Hsp90 Chaperone. J.Biol.Chem., 279, 2004
1TCR	MURINE T-CELL ANTIGEN RECEPTOR 2C CLONE 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Garcia, K.C, Degano, M, Stanfield, R.L, Wilson, I.A. 登録日 1996-09-12 公開日 1997-03-12 最終更新日 2024-10-23 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 An alphabeta T cell receptor structure at 2.5 A and its orientation in the TCR-MHC complex. Science, 274, 1996
1YV2	Hepatitis C virus NS5B RNA-dependent RNA Polymerase genotype 2a 分子名称: GLYCEROL, RNA dependent RNA polymerase, SULFATE ION 著者 Biswal, B.K, Cherney, M.M, Wang, M, Chan, L, Yannopoulos, C.G, Bilimoria, D, Nicolas, O, Bedard, J, James, M.N.G. 登録日 2005-02-14 公開日 2005-03-22 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Crystal Structures of the RNA-dependent RNA Polymerase Genotype 2a of Hepatitis C Virus Reveal Two Conformations and Suggest Mechanisms of Inhibition by Non-nucleoside Inhibitors J.Biol.Chem., 280, 2005
1SXT	STAPHYLOCOCCAL ENTEROTOXIN TYPE A (SEA) CO-CRYSTALLISED WITH ZINC 分子名称: STAPHYLOCOCCAL ENTEROTOXIN TYPE A, ZINC ION 著者 Sundstrom, S.M. 登録日 1996-11-14 公開日 1997-11-19 最終更新日 2024-10-30 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 The Co-crystal structure of staphylococcal enterotoxin type A with Zn2+ at 2.7 A resolution. Implications for major histocompatibility complex class II binding. J.Biol.Chem., 271, 1996
2AK2	ADENYLATE KINASE ISOENZYME-2 分子名称: ADENYLATE KINASE ISOENZYME-2, SULFATE ION 著者 Schlauderer, G.J, Schulz, G.E. 登録日 1995-12-29 公開日 1996-06-10 最終更新日 2024-10-30 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 The structure of bovine mitochondrial adenylate kinase: comparison with isoenzymes in other compartments. Protein Sci., 5, 1996
1ZE1	Conformational Change of Pseudouridine 55 Synthase upon Its Association with RNA Substrate 分子名称: MAGNESIUM ION, tRNA pseudouridine synthase B 著者 Phannachet, K, Huang, R.H. 登録日 2005-04-16 公開日 2005-04-26 最終更新日 2024-10-30 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Conformational change of pseudouridine 55 synthase upon its association with RNA substrate Nucleic Acids Res., 32, 2004
1TF6	CO-CRYSTAL STRUCTURE OF XENOPUS TFIIIA ZINC FINGER DOMAIN BOUND TO THE 5S RIBOSOMAL RNA GENE INTERNAL CONTROL REGION 分子名称: DNA (5'-D(*AP*CP*GP*GP*GP*CP*CP*TP*GP*GP*TP*TP*AP*GP*TP*AP*C P*CP*TP*GP*GP*AP* TP*GP*GP*GP*AP*GP*AP*CP*C)-3'), DNA (5'-D(*TP*GP*GP*TP*CP*TP*CP*CP*CP*AP*TP*CP*CP*AP*GP*GP*T P*AP*CP*TP*AP*AP* CP*CP*AP*GP*GP*CP*CP*CP*G)-3'), PROTEIN (TRANSCRIPTION FACTOR IIIA), ... 著者 Nolte, R.T, Conlin, R.M, Harrison, S.C, Brown, R.S. 登録日 1998-03-02 公開日 1998-07-10 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 Differing roles for zinc fingers in DNA recognition: structure of a six-finger transcription factor IIIA complex. Proc.Natl.Acad.Sci.USA, 95, 1998
1YVN	THE YEAST ACTIN VAL 159 ASN MUTANT COMPLEX WITH HUMAN GELSOLIN SEGMENT 1. 分子名称: ADENOSINE-5'-TRIPHOSPHATE, CALCIUM ION, MAGNESIUM ION, ... 著者 Vorobiev, S.M, Belmont, L.D, Drubin, D.G, Almo, S.C. 登録日 1999-03-23 公開日 2000-03-23 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Crystal structure of yeast actin V159N mutant To be Published
1TFG	AN UNUSUAL FEATURE REVEALED BY THE CRYSTAL STRUCTURE AT 2.2 ANGSTROMS RESOLUTION OF HUMAN TRANSFORMING GROWTH FACTOR-BETA2 分子名称: TRANSFORMING GROWTH FACTOR, BETA 2 著者 Gruetter, M, Schlunegger, M. 登録日 1992-11-17 公開日 1993-10-31 最終更新日 2019-08-14 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 An unusual feature revealed by the crystal structure at 2.2 A resolution of human transforming growth factor-beta 2. Nature, 358, 1992
1YVZ	Hepatitis C Virus RNA Polymerase Genotype 2a In Complex With Non- Nucleoside Analogue Inhibitor 分子名称: 3-[(2,4-DICHLOROBENZOYL)(ISOPROPYL)AMINO]-5-PHENYLTHIOPHENE-2-CARBOXYLIC ACID, RNA dependent RNA polymerase, SULFATE ION 著者 Biswal, B.K, Cherney, M.M, Wang, M, Chan, L, Yannopoulos, C.G, Bilimoria, D, Nicolas, O, Bedard, J, James, M.N.G. 登録日 2005-02-16 公開日 2005-03-22 最終更新日 2024-10-30 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Crystal structures of the RNA dependent RNA polymerase genotype 2a of hepatitis C virus reveal two conformations and suggest mechanisms of inhibition by non-nucleoside inhibitors. J.Biol.Chem., 280, 2005
1THO	CRYSTAL STRUCTURE OF A MUTANT ESCHERICHIA COLI THIOREDOXIN WITH AN ARGININE INSERTION IN THE ACTIVE SITE 分子名称: COPPER (II) ION, THIOREDOXIN 著者 Nikkola, M, Langsetmo, K, Fuchs, J.A, Eklund, H. 登録日 1993-01-28 公開日 1993-10-31 最終更新日 2017-11-29 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Crystal Structure of a Mutant Escherichia Coli Thioredoxin with an Arginine Insertion in the Active Site To be Published
1ZGB	Crystal Structure of Torpedo Californica Acetylcholinesterase in Complex With an (R)-Tacrine(10)-Hupyridone Inhibitor. 分子名称: (5R)-5-{[10-(1,2,3,4-TETRAHYDROACRIDIN-9-YLAMINO)DECYL]AMINO}-5,6,7,8-TETRAHYDROQUINOLIN-2(1H)-ONE, 2-acetamido-2-deoxy-beta-D-glucopyranose, Acetylcholinesterase 著者 Haviv, H, Wong, D.M, Greenblatt, H.M, Carlier, P.R, Pang, Y.P, Silman, I, Sussman, J.L, Israel Structural Proteomics Center (ISPC) 登録日 2005-04-21 公開日 2005-08-16 最終更新日 2024-10-16 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Crystal Packing Mediates Enantioselective Ligand Recognition at the Peripheral Site of Acetylcholinesterase J.Am.Chem.Soc., 127, 2005
1ZGQ	Crystal Structure of the Discosoma Red Fluorescent Protein (DsRed) Variant Q66M 分子名称: DI(HYDROXYETHYL)ETHER, Red fluorescent protein drFP583 著者 Tubbs, J.L, Tainer, J.A, Getzoff, E.D. 登録日 2005-04-21 公開日 2005-08-02 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Crystallographic structures of discosoma red fluorescent protein with immature and mature chromophores: linking Peptide bond trans-cis isomerization and acylimine formation in chromophore maturation. Biochemistry, 44, 2005
2AY7	AROMATIC AMINO ACID AMINOTRANSFERASE WITH 4-PHENYLBUTYRIC ACID 分子名称: 4-PHENYL-BUTANOIC ACID, AROMATIC AMINO ACID AMINOTRANSFERASE, PYRIDOXAL-5'-PHOSPHATE 著者 Okamoto, A, Hirotsu, K, Kagamiyama, H. 登録日 1998-08-06 公開日 1999-02-02 最終更新日 2023-08-09 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 The active site of Paracoccus denitrificans aromatic amino acid aminotransferase has contrary properties: flexibility and rigidity. Biochemistry, 38, 1999
1ATK	CRYSTAL STRUCTURE OF THE CYSTEINE PROTEASE HUMAN CATHEPSIN K IN COMPLEX WITH THE COVALENT INHIBITOR E-64 分子名称: CATHEPSIN K, N-[N-[1-HYDROXYCARBOXYETHYL-CARBONYL]LEUCYLAMINO-BUTYL]-GUANIDINE 著者 Zhao, B, Smith, W.W, Janson, C.A, Abdel-Meguid, S.S. 登録日 1996-12-19 公開日 1998-02-04 最終更新日 2024-10-09 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Crystal structure of human osteoclast cathepsin K complex with E-64. Nat.Struct.Biol., 4, 1997

<890891892893894895896897898899900901902903904905>