PDB: 48062 件ウェブページステータス検索Chemie searchBIRD

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5K7U	Crystal structure of the catalytic domains of Mettl3/Mettl14 complex with SAM 分子名称: N6-adenosine-methyltransferase 70 kDa subunit, N6-adenosine-methyltransferase subunit METTL14, S-ADENOSYLMETHIONINE 著者 Wang, P, Doxtader, K.A, Nam, Y. 登録日 2016-05-26 公開日 2016-07-06 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Structural Basis for Cooperative Function of Mettl3 and Mettl14 Methyltransferases. Mol.Cell, 63, 2016
5K8O	Mn2+/5NSA-bound 5-nitroanthranilate aminohydrolase 分子名称: 5-nitroanthranilic acid aminohydrolase, 5-nitrosalicylic acid, MANGANESE (II) ION 著者 Kalyoncu, S. 登録日 2016-05-30 公開日 2016-10-05 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.893 Å) 主引用文献 Enzymatic hydrolysis by transition-metal-dependent nucleophilic aromatic substitution. Nat.Chem.Biol., 12, 2016
5JYX	Crystal structure of the covalent thioimide intermediate of the archaeosine synthase QueF-Like 分子名称: 2-amino-5-[(Z)-iminomethyl]-3,7-dihydro-4H-pyrrolo[2,3-d]pyrimidin-4-one, Archeaosine synthase QueF-Like, SODIUM ION 著者 Mei, X, Swairjo, M.A. 登録日 2016-05-15 公開日 2016-11-09 最終更新日 2020-01-29 実験手法 X-RAY DIFFRACTION (2.74 Å) 主引用文献 Crystal structure of the archaeosine synthase QueF-like-Insights into amidino transfer and tRNA recognition by the tunnel fold. Proteins, 85, 2017
5K02	Structure of human SOD1 with T2D mutation 分子名称: COPPER (II) ION, Superoxide dismutase [Cu-Zn], ZINC ION 著者 Fay, J.M, Zhu, C, Cui, W, Ke, H, Dokholyan, N.V. 登録日 2016-05-17 公開日 2016-11-23 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.99 Å) 主引用文献 A Phosphomimetic Mutation Stabilizes SOD1 and Rescues Cell Viability in the Context of an ALS-Associated Mutation. Structure, 24, 2016
5KBA	Computational Design of Self-Assembling Cyclic Protein Homooligomers 分子名称: Designed protein ANK1C2 著者 Sankaran, B, Zwart, P.H, Fallas, J.A, Pereira, J.H, Ueda, G, Baker, D. 登録日 2016-06-02 公開日 2017-04-12 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (2.601 Å) 主引用文献 Computational design of self-assembling cyclic protein homo-oligomers. Nat Chem, 9, 2017
5KBX	Co-crystal structure of the Saccharomyces cerevisiae histidine phosphotransfer signaling protein Ypd1 and the receiver domain of its downstream response regulator Ssk1 分子名称: GLYCEROL, Osmolarity two-component system protein SSK1, PHOSPHATE ION, ... 著者 Menon, S.K, West, A.H. 登録日 2016-06-03 公開日 2017-06-07 最終更新日 2019-11-27 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Insights revealed by the co-crystal structure of the Saccharomyces cerevisiae histidine phosphotransfer signaling protein Ypd1 and the receiver domain of its downstream response regulator Ssk1 To Be Published
5JQ9	Yersinia pestis DHPS with pterine-sulfa conjugate Compound 16 分子名称: 1,2-ETHANEDIOL, 4-{[(2-amino-4-oxo-3,4-dihydropteridin-6-yl)methyl]amino}-N-(3,4-dimethyl-1,2-oxazol-5-yl)benzene-1-sulfonamide, Dihydropteroate synthase 著者 Wu, Y, White, S.W. 登録日 2016-05-04 公開日 2016-08-10 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.101 Å) 主引用文献 Pterin-sulfa conjugates as dihydropteroate synthase inhibitors and antibacterial agents. Bioorg.Med.Chem.Lett., 26, 2016
5JTW	Crystal structure of complement C4b re-refined using iMDFF 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Complement C4-A 著者 Croll, T.I, Andersen, G.R. 登録日 2016-05-09 公開日 2016-08-10 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (3.5 Å) 主引用文献 Re-evaluation of low-resolution crystal structures via interactive molecular-dynamics flexible fitting (iMDFF): a case study in complement C4. Acta Crystallogr D Struct Biol, 72, 2016
5KN9	MutY N-terminal domain in complex with DNA containing an intrahelical oxoG:A base-pair 分子名称: Adenine DNA glycosylase, CALCIUM ION, DNA (5'-D(*AP*GP*CP*AP*CP*AP*GP*GP*AP*T)-3'), ... 著者 Wang, L, Chakravarthy, S, Verdine, G.L. 登録日 2016-06-27 公開日 2017-02-08 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.93 Å) 主引用文献 Structural Basis for the Lesion-scanning Mechanism of the MutY DNA Glycosylase. J. Biol. Chem., 292, 2017
5KP0	Recognition and targeting mechanisms by chaperones in flagella assembly and operation 分子名称: Flagellar protein FliT,Flagellum-specific ATP synthase 著者 Khanra, N.K, Rossi, P, Economou, A, Kalodimos, C.G. 登録日 2016-07-01 公開日 2016-08-17 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 Recognition and targeting mechanisms by chaperones in flagellum assembly and operation. Proc.Natl.Acad.Sci.USA, 113, 2016
5KSR	Stationary phase survival protein E (SurE) from Xylella fastidiosa - XFSurE-TB (Tetramer Bigger). 分子名称: 5'-nucleotidase SurE, CHLORIDE ION, IODIDE ION, ... 著者 Machado, A.T.P, Fonseca, E.M.B, Dos Reis, M.A, Saraiva, A.M, Dos Santos, C.A, De Toledo, M.A, Polikarpov, I, De Souza, A.P, De Aparicio, R, Iulek, J. 登録日 2016-07-09 公開日 2017-07-19 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.96 Å) 主引用文献 Conformational variability of the stationary phase survival protein E from Xylella fastidiosa revealed by X-ray crystallography, small-angle X-ray scattering studies, and normal mode analysis. Proteins, 85, 2017
5L1H	AMPA subtype ionotropic glutamate receptor GluA2 in complex with noncompetitive inhibitor GYKI53655 分子名称: (8R)-5-(4-aminophenyl)-N,8-dimethyl-8,9-dihydro-2H,7H-[1,3]dioxolo[4,5-h][2,3]benzodiazepine-7-carboxamide, 2-acetamido-2-deoxy-beta-D-glucopyranose, Glutamate receptor 2 著者 Yelshanskaya, M.V, Singh, A.K, Sampson, J.M, Sobolevsky, A.I. 登録日 2016-07-29 公開日 2016-10-19 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (3.801 Å) 主引用文献 Structural Bases of Noncompetitive Inhibition of AMPA-Subtype Ionotropic Glutamate Receptors by Antiepileptic Drugs. Neuron, 91, 2016
5KK2	Architecture of fully occupied GluA2 AMPA receptor - TARP complex elucidated by single particle cryo-electron microscopy 分子名称: Glutamate receptor 2, Voltage-dependent calcium channel gamma-2 subunit 著者 Zhao, Y, Chen, S, Yoshioka, C, Baconguis, I, Gouaux, E. 登録日 2016-06-20 公開日 2016-07-06 最終更新日 2018-07-18 実験手法 ELECTRON MICROSCOPY (7.3 Å) 主引用文献 Architecture of fully occupied GluA2 AMPA receptor-TARP complex elucidated by cryo-EM. Nature, 536, 2016
5KJ4	Crystal Structure of Mouse Protocadherin-15 EC9-10 分子名称: CALCIUM ION, Protocadherin-15 著者 Araya-Secchi, R, Sotomayor, M. 登録日 2016-06-17 公開日 2016-11-23 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (3.35 Å) 主引用文献 An elastic element in the protocadherin-15 tip link of the inner ear. Nat Commun, 7, 2016
5KN5	TGFalpha/Epiregulin complex with neutralizing antibody LY3016859 分子名称: Epiregulin Antibody LY3016859 Fab Heavy Chain, Epiregulin Antibody LY3016859 Fab Light Chain, Protransforming growth factor alpha, ... 著者 Atwell, S, Boyles, J.S, Clawson, D.K, Druzina, Z, Josef, G.H, Weichert, K, Witcher, D.R. 登録日 2016-06-27 公開日 2016-08-31 最終更新日 2016-11-02 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Structural basis of selectivity and neutralizing activity of a TGF alpha /epiregulin specific antibody. Protein Sci., 25, 2016
5KR7	KDM4C bound to pyrazolo-pyrimidine scaffold 分子名称: 6-ethyl-2,5-dimethyl-7-oxidanylidene-4~{H}-pyrazolo[1,5-a]pyrimidine-3-carbonitrile, CHLORIDE ION, FE (II) ION, ... 著者 Bellon, S.F, Poy, F, Setser, J.W. 登録日 2016-07-07 公開日 2016-08-17 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Identification of potent, selective KDM5 inhibitors. Bioorg.Med.Chem.Lett., 26, 2016
5KSQ	Stationary phase survival protein E (SurE) from Xylella fastidiosa 分子名称: 5'-nucleotidase SurE, IODIDE ION, MANGANESE (II) ION, ... 著者 Machado, A.T.P, Fonseca, E.M.B, Dos Reis, M.A, Saraiva, A.M, Dos Santos, C.A, De Toledo, M.A, Polikarpov, I, De Souza, A.P, Aparicio, R, Iulek, J. 登録日 2016-07-09 公開日 2017-07-19 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.63 Å) 主引用文献 Conformational variability of the stationary phase survival protein E from Xylella fastidiosa revealed by X-ray crystallography, small-angle X-ray scattering studies, and normal mode analysis. Proteins, 85, 2017
5L0F	Human metavinculin quadruple mutant (residues 959-1134) 分子名称: GLYCEROL, Vinculin 著者 Chinthalapudi, K, Izard, T. 登録日 2016-07-27 公開日 2016-08-31 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.76 Å) 主引用文献 Differential lipid binding of vinculin isoforms promotes quasi-equivalent dimerization. Proc.Natl.Acad.Sci.USA, 113, 2016
5LAS	HIF prolyl hydroxylase 2 (PHD2-R281C/P317C/R396T) cross-linked to HIF-1alpha NODD-L397C/D412C and N-oxalylglycine (NOG) (complex-3) 分子名称: Egl nine homolog 1, Hypoxia-inducible factor 1-alpha, MANGANESE (II) ION, ... 著者 Chowdhury, R, Schofield, C.J. 登録日 2016-06-14 公開日 2016-08-31 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Structural basis for oxygen degradation domain selectivity of the HIF prolyl hydroxylases. Nat Commun, 7, 2016
5L1P	X-ray Structure of Cytochrome P450 PntM with Pentalenolactone 分子名称: PROTOPORPHYRIN IX CONTAINING FE, Pentalenolactone synthase, pentalenolactone 著者 Duan, L, Jogl, G, Cane, D.E. 登録日 2016-07-29 公開日 2016-09-14 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.28 Å) 主引用文献 The Cytochrome P450-Catalyzed Oxidative Rearrangement in the Final Step of Pentalenolactone Biosynthesis: Substrate Structure Determines Mechanism. J.Am.Chem.Soc., 138, 2016
5KLM	Crystal structure of 2-hydroxymuconate-6-semialdehyde derived intermediate in NAD(+)-bound 2-aminomuconate 6-semialdehyde dehydrogenase N169D 分子名称: 2-aminomuconate 6-semialdehyde dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, SODIUM ION 著者 Yang, Y, Davis, I, Ha, U, Wang, Y, Shin, I, Liu, A. 登録日 2016-06-24 公開日 2016-11-09 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.102 Å) 主引用文献 A Pitcher-and-Catcher Mechanism Drives Endogenous Substrate Isomerization by a Dehydrogenase in Kynurenine Metabolism. J.Biol.Chem., 291, 2016
5KLF	Structure of CBM_E1, a novel carbohydrate-binding module found by sugar cane soil metagenome, complexed with cellopentaose and gadolinium ion 分子名称: Carbohydrate binding module E1, GADOLINIUM ATOM, beta-D-glucopyranose-(1-4)-beta-D-glucopyranose-(1-4)-beta-D-glucopyranose-(1-4)-beta-D-glucopyranose-(1-4)-beta-D-glucopyranose 著者 Liberato, M.V, Campos, B.M, Zeri, A.C.M, Squina, F.M. 登録日 2016-06-24 公開日 2016-09-21 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (1.801 Å) 主引用文献 A Novel Carbohydrate-binding Module from Sugar Cane Soil Metagenome Featuring Unique Structural and Carbohydrate Affinity Properties. J.Biol.Chem., 291, 2016
5KPF	Crystal structure of cytochrome c - Phenyl-trisulfonatocalix[4]arene complex 分子名称: Cytochrome c iso-1, HEME C, NITRATE ION, ... 著者 Doolan, A.M, Rennie, M.L, Crowley, P.B. 登録日 2016-07-04 公開日 2017-07-12 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.698 Å) 主引用文献 Protein Recognition by Functionalized Sulfonatocalix[4]arenes. Chemistry, 24, 2018
5L5G	Plexin A2 full extracellular region, domains 1 to 8 modeled, data to 10 angstrom 分子名称: Plexin-A2 著者 Janssen, B.J.C, Kong, Y, Malinauskas, T, Vangoor, V.R, Coles, C.H, Kaufmann, R, Ni, T, Gilbert, R.J.C, Padilla-Parra, S, Pasterkamp, R.J, Jones, E.Y. 登録日 2016-05-28 公開日 2016-07-06 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (10 Å) 主引用文献 Structural Basis for Plexin Activation and Regulation. Neuron, 91, 2016
5L8B	Crystal structure of Rhodospirillum rubrum Rru_A0973 mutant E62A 分子名称: CALCIUM ION, Uncharacterized protein 著者 He, D, Hughes, S, Vanden-Hehir, S, Georgiev, A, Altenbach, K, Tarrant, E, Mackay, C.L, Waldron, K.J, Clarke, D.J, Marles-Wright, J. 登録日 2016-06-07 公開日 2016-08-31 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.21 Å) 主引用文献 Structural characterization of encapsulated ferritin provides insight into iron storage in bacterial nanocompartments. Elife, 5, 2016

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