5KN9

MutY N-terminal domain in complex with DNA containing an intrahelical oxoG:A base-pair

Summary for 5KN9

• Entry DOI: 10.2210/pdb5kn9/pdb
• Related: 5KN8
• Descriptor: Adenine DNA glycosylase, DNA (5'-D(*AP*TP*CP*CP*(8OG)P*GP*TP*GP*CP*T)-3'), DNA (5'-D(*AP*GP*CP*AP*CP*AP*GP*GP*AP*T)-3'), ... (6 entities in total)
• Functional Keywords: adenine glycosylase, oxog, dna repair protein, intrahelical lesion recognition, hydrolase-dna complex, hydrolase/dna
• Biological source: Geobacillus stearothermophilus; More
• Total number of polymer chains: 3
• Total formula weight: 33256.32

Authors

Wang, L.,Chakravarthy, S.,Verdine, G.L. (deposition date: 2016-06-27, release date: 2017-02-08, Last modification date: 2023-09-27)

• Primary citation: Wang, L.,Chakravarthy, S.,Verdine, G.L.; Structural Basis for the Lesion-scanning Mechanism of the MutY DNA Glycosylase.; J. Biol. Chem., 292:5007-5017, 2017; PubMed: 28130451; DOI: 10.1074/jbc.M116.757039

Experimental method

X-RAY DIFFRACTION (1.93 Å)