PDB: 95574 件ウェブページステータス検索Chemie searchBIRD

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6GAW	Unique features of mammalian mitochondrial translation initiation revealed by cryo-EM. This file contains the complete 55S ribosome. 分子名称: 12S ribosomal RNA, mitochondrial, 16S ribosomal RNA, ... 著者 Kummer, E, Leibundgut, M, Boehringer, D, Ban, N. 登録日 2018-04-13 公開日 2018-08-22 最終更新日 2019-12-11 実験手法 ELECTRON MICROSCOPY (3.2 Å) 主引用文献 Unique features of mammalian mitochondrial translation initiation revealed by cryo-EM. Nature, 560, 2018
6GAZ	Unique features of mammalian mitochondrial translation initiation revealed by cryo-EM. This file contains the 28S ribosomal subunit. 分子名称: 12S ribosomal RNA, mitochondrial, 28S ribosomal protein S18b, ... 著者 Kummer, E, Leibundgut, M, Boehringer, D, Ban, N. 登録日 2018-04-13 公開日 2018-08-08 最終更新日 2019-12-18 実験手法 ELECTRON MICROSCOPY (3.1 Å) 主引用文献 Unique features of mammalian mitochondrial translation initiation revealed by cryo-EM. Nature, 560, 2018
8AUP	Structure of hARG1 with a novel inhibitor. 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, 2-[(1~{R},3~{R},4~{S})-3-azanyl-3-carboxy-4-[(dimethylamino)methyl]cyclohexyl]ethyl-$l^{3}-oxidanyl-bis(oxidanyl)boron, Arginase-1, ... 著者 Napiorkowska-Gromadzka, A, Nowak, E, Nowotny, M. 登録日 2022-08-25 公開日 2023-03-29 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.17 Å) 主引用文献 Arginase 1/2 Inhibitor OATD-02: From Discovery to First-in-man Setup in Cancer Immunotherapy. Mol.Cancer Ther., 22, 2023
6T76	PII-like protein CutA from Nostoc sp. PCC 7120 in apo form 分子名称: Periplasmic divalent cation tolerance protein, SULFATE ION 著者 Selim, K.A, Albrecht, R, Forchhammer, K, Hartmann, M.D. 登録日 2019-10-21 公開日 2020-07-22 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Functional and structural characterization of PII-like protein CutA does not support involvement in heavy metal tolerance and hints at a small-molecule carrying/signaling role. Febs J., 288, 2021
6T7E	PII-like protein CutA from Nostoc sp. PCC7120 in complex with MES 分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Periplasmic divalent cation tolerance protein 著者 Selim, K.A, Albrecht, R, Forchhammer, K, Hartmann, M.D. 登録日 2019-10-21 公開日 2020-07-22 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.45 Å) 主引用文献 Functional and structural characterization of PII-like protein CutA does not support involvement in heavy metal tolerance and hints at a small-molecule carrying/signaling role. Febs J., 288, 2021
6GB2	Unique features of mammalian mitochondrial translation initiation revealed by cryo-EM. This file contains the 39S ribosomal subunit. 分子名称: 'Mitochondrial ribosomal protein L30, 'Mitochondrial ribosomal protein L55, 'Mitochondrial ribosomal protein L59, ... 著者 Kummer, E, Leibundgut, M, Boehringer, D, Ban, N. 登録日 2018-04-13 公開日 2018-08-08 最終更新日 2024-05-15 実験手法 ELECTRON MICROSCOPY (3.2 Å) 主引用文献 Unique features of mammalian mitochondrial translation initiation revealed by cryo-EM. Nature, 560, 2018
4I4C	Crystal structure of the protein frsA complexed with unknown ligand 分子名称: 2-(2-{2-[2-(2-METHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHANOL, GLYCEROL, HEXANOIC ACID, ... 著者 Fedorov, A.A, Fedorov, E.V, Desai, B, Gerlt, J.A, Richards, N, Almo, S.C. 登録日 2012-11-27 公開日 2013-10-09 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Computational, structural, and kinetic evidence that Vibrio vulnificus FrsA is not a cofactor-independent pyruvate decarboxylase. Biochemistry, 52, 2013
5M42	Structure of Thermus thermophilus L-proline dehydrogenase lacking alpha helices A, B and C 分子名称: FLAVIN MONONUCLEOTIDE, Proline dehydrogenase 著者 Martinez-Julvez, M, Huijbers, M.M.E, van Berkel, W.J.H, Medina, M. 登録日 2016-10-18 公開日 2017-03-15 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Proline dehydrogenase from Thermus thermophilus does not discriminate between FAD and FMN as cofactor. Sci Rep, 7, 2017
4QGB	Crystal structure of mutant ribosomal protein G219V TthL1 分子名称: 50S ribosomal protein L1, ACETATE ION, CHLORIDE ION 著者 Gabdulkhakov, A.G, Nevskaya, N.A, Nikonov, S.V. 登録日 2014-05-22 公開日 2015-02-11 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Protein-RNA affinity of ribosomal protein L1 mutants does not correlate with the number of intermolecular interactions. Acta Crystallogr.,Sect.D, 71, 2015
4QG3	Crystal structure of mutant ribosomal protein G219V TthL1 in complex with 80nt 23S RNA from Thermus thermophilus 分子名称: 50S ribosomal protein L1, BETA-MERCAPTOETHANOL, ISOPROPYL ALCOHOL, ... 著者 Gabdulkhakov, A.G, Nevskaya, N.A, Nikonov, S.V. 登録日 2014-05-22 公開日 2015-02-11 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Protein-RNA affinity of ribosomal protein L1 mutants does not correlate with the number of intermolecular interactions. Acta Crystallogr.,Sect.D, 71, 2015
6XZ2	Crystal structure of E. Coli purine nucleoside phosphorylase mutant Y160W with SO4 and Formycin A 分子名称: (1S)-1-(7-amino-1H-pyrazolo[4,3-d]pyrimidin-3-yl)-1,4-anhydro-D-ribitol, Purine nucleoside phosphorylase DeoD-type, SULFATE ION 著者 Narczyk, M, Bzowska, A. 登録日 2020-01-31 公開日 2021-02-10 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.65000308 Å) 主引用文献 Single tryptophan Y160W mutant of homooligomeric E. coli purine nucleoside phosphorylase implies that dimers forming the hexamer are functionally not equivalent. Sci Rep, 11, 2021
4QVI	Crystal structure of mutant ribosomal protein M218L TthL1 in complex with 80nt 23S RNA from Thermus thermophilus 分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 50S ribosomal protein L1, ACETATE ION, ... 著者 Gabdulkhakov, A.G, Nevskaya, N.A, NIkonov, S.V. 登録日 2014-07-15 公開日 2015-02-11 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Protein-RNA affinity of ribosomal protein L1 mutants does not correlate with the number of intermolecular interactions. Acta Crystallogr.,Sect.D, 71, 2015
4REO	Mutant ribosomal protein l1 from thermus thermophilus with threonine 217 replaced by valine 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, 50S ribosomal protein L1, GLYCINE, ... 著者 Gabdulkhakov, A.G, Nevskaya, N.A, Tishchenko, S.V, Nikonov, S.V. 登録日 2014-09-23 公開日 2015-03-18 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.35 Å) 主引用文献 Protein-RNA affinity of ribosomal protein L1 mutants does not correlate with the number of intermolecular interactions. Acta Crystallogr.,Sect.D, 71, 2015
3N3G	4-(3-Trifluoromethylphenyl)-pyrimidine-2-carbonitrile as cathepsin S inhibitors: N3, not N1 is critically important 分子名称: (E)-1-(6-{4-[3-(4-methylpiperazin-1-yl)propoxy]-3-(trifluoromethyl)phenyl}pyridin-2-yl)methanimine, 6-{4-[3-(4-methylpiperazin-1-yl)propoxy]-3-(trifluoromethyl)phenyl}pyridine-2-carbonitrile, Cathepsin S, ... 著者 Fradera, X, Uitdehaag, J.C.M, van Zeeland, M. 登録日 2010-05-20 公開日 2010-07-14 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 4-(3-Trifluoromethylphenyl)-pyrimidine-2-carbonitrile as cathepsin S inhibitors: N3, not N1 is critically important. Bioorg.Med.Chem.Lett., 20, 2010
5M5E	Crystal structure of a interleukin-2 variant in complex with interleukin-2 receptor 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Klein, C, Freimoser-Grundschober, A, Waldhauer, I, Stihle, M, Birk, M, Benz, J. 登録日 2016-10-21 公開日 2017-05-03 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Cergutuzumab amunaleukin (CEA-IL2v), a CEA-targeted IL-2 variant-based immunocytokine for combination cancer immunotherapy: Overcoming limitations of aldesleukin and conventional IL-2-based immunocytokines. Oncoimmunology, 6, 2017
6ZTW	Crystal Structure of catalase HPII from Escherichia coli (serendipitously crystallized) 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ... 著者 Grzechowiak, M, Sekula, B, Ruszkowski, M. 登録日 2020-07-20 公開日 2020-10-07 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.84 Å) 主引用文献 Serendipitous crystallization of E. coli HPII catalase, a sequel to "the tale usually not told". Acta Biochim.Pol., 68, 2021
8HNP	Archaeal transcription factor Mutant 分子名称: Archaeal transcription regulator 著者 Bae, D.W, Cha, S.S. 登録日 2022-12-08 公開日 2023-09-13 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (3.39 Å) 主引用文献 An archaeal transcription factor EnfR with a novel 'eighth note' fold controls hydrogen production of a hyperthermophilic archaeon Thermococcus onnurineus NA1. Nucleic Acids Res., 51, 2023
4CMM	Structure of human CD47 in complex with human Signal Regulatory Protein (SIRP) alpha v1 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, LEUKOCYTE SURFACE ANTIGEN CD47, TYROSINE-PROTEIN PHOSPHATASE NON-RECEPTOR TYPE SUBSTRATE 1 著者 Hatherley, D, Lea, S.M, Johnson, S, Barclay, A.N. 登録日 2014-01-16 公開日 2014-02-26 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (1.92 Å) 主引用文献 Polymorphisms in the Human Inhibitory Signal-Regulatory Protein Alpha Do not Affect Binding to its Ligand Cd47. J.Biol.Chem., 289, 2014
8HNO	Archaeal transcription factor Wild type 分子名称: Archaeal transcription regulator 著者 Bae, D.W, Cha, S.S. 登録日 2022-12-08 公開日 2023-09-13 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.84 Å) 主引用文献 An archaeal transcription factor EnfR with a novel 'eighth note' fold controls hydrogen production of a hyperthermophilic archaeon Thermococcus onnurineus NA1. Nucleic Acids Res., 51, 2023
6ZTX	Crystal Structure of catalase HPII from Escherichia coli (serendipitously crystallized) 分子名称: 1,2-ETHANEDIOL, CIS-HEME D HYDROXYCHLORIN GAMMA-SPIROLACTONE, Catalase HPII, ... 著者 Grzechowiak, M, Sekula, B, Ruszkowski, M. 登録日 2020-07-20 公開日 2020-10-07 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.3 Å) 主引用文献 Serendipitous crystallization of E. coli HPII catalase, a sequel to "the tale usually not told". Acta Biochim.Pol., 68, 2021
3OXQ	Crystal Structure of Ca2+/CaM-CaV1.2 pre-IQ/IQ domain complex 分子名称: CALCIUM ION, Calmodulin, Voltage-dependent L-type calcium channel subunit alpha-1C 著者 Kim, E.Y, Rumpf, C.H, Van Petegem, F, Arant, R, Findeisen, F, Cooley, E.S, Isacoff, E.Y, Minor, D.L. 登録日 2010-09-21 公開日 2010-11-03 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.55 Å) 主引用文献 Multiple C-terminal tail Ca(2+)/CaMs regulate Ca(V)1.2 function but do not mediate channel dimerization. Embo J., 29, 2010
6ZTV	Crystal Structure of catalase HPII from Escherichia coli (serendipitously crystallized) 分子名称: 1,2-ETHANEDIOL, CIS-HEME D HYDROXYCHLORIN GAMMA-SPIROLACTONE, Catalase HPII, ... 著者 Grzechowiak, M, Sekula, B, Ruszkowski, M. 登録日 2020-07-20 公開日 2020-10-07 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.78 Å) 主引用文献 Serendipitous crystallization of E. coli HPII catalase, a sequel to "the tale usually not told". Acta Biochim.Pol., 68, 2021
4FM4	Wild Type Fe-type Nitrile Hydratase from Comamonas testosteroni Ni1 分子名称: FE (III) ION, Nitrile hydratase alpha subunit, Nitrile hydratase beta subunit, ... 著者 Kuhn, M.L, Martinez, S, Gumataotao, N, Bornscheuer, U, Liu, D, Holz, R.C. 登録日 2012-06-15 公開日 2012-08-22 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.384 Å) 主引用文献 The Fe-type nitrile hydratase from Comamonas testosteroni Ni1 does not require an activator accessory protein for expression in Escherichia coli. Biochem.Biophys.Res.Commun., 424, 2012
6JQ3	Crystal Structure of H2-Kb in complex with a DPAGT1 mutant peptide 分子名称: Beta-2-microglobulin, DPAGT1 mutant antigen SIIVFNLL, H-2 class I histocompatibility antigen, ... 著者 Bai, P, Zhou, Q, Wei, P, Yin, L. 登録日 2019-03-28 公開日 2020-05-06 最終更新日 2021-02-17 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Immune-based mutation classification enables neoantigen prioritization and immune feature discovery in cancer immunotherapy. Oncoimmunology, 10, 2021
6JQ2	Crystal Structure of H2-Kb in complex with a DPAGT1 self-peptide 分子名称: Beta-2-microglobulin, DPATG1 antigen SIIVFNLV, H-2 class I histocompatibility antigen, ... 著者 Bai, P, Yin, L. 登録日 2019-03-28 公開日 2020-04-01 最終更新日 2021-02-17 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Immune-based mutation classification enables neoantigen prioritization and immune feature discovery in cancer immunotherapy. Oncoimmunology, 10, 2021

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